Snippet Search

Searching 12,329,257 documents.
Discover how a particular term or phrase is used in scientific literature

Showing 1 to 25 of 13898 matching articles

Results per page:

... findings suggesting a pro-oncogenic role for  p53 
Cooperation of p53 Mutations with Other Oncogenic Alterations in Cancer
Cooperation of p53 Mutations with Other Oncogenic Alterations in Cancer
Girardini, Javier E.; Walerych, Dawid; Sal, Giannino
point mutants, more than 30 years of research ...
... The presence of a functional  p53 
The p53-Mdm2 Loop: A Critical Juncture of Stress Response
The p53-Mdm2 Loop: A Critical Juncture of Stress Response
Levav-Cohen, Yaara; Goldberg, Zehavit; Tan, Kah Hin; Alsheich-Bartok, Osnat; Zuckerman, Valentina; Haupt, Sue; Haupt, Ygal
protein is a key factor for the proper ...
... in the genesis and progression of cancer, mutant  p53 
Mutant p53 and the Response to Chemotherapy and Radiation
Mutant p53 and the Response to Chemotherapy and Radiation
Tchelebi, Leila; Ashamalla, Hani; Graves, Paul R.
also appears to play a significant role in the ...
... The tumor suppressor  p53 
Targeting p53-MDM2-MDMX Loop for Cancer Therapy
Targeting p53-MDM2-MDMX Loop for Cancer Therapy
Zhang, Qi; Zeng, Shelya X.; Lu, Hua
plays a central role in anti-tumorigenesis and ...
... Reinstatement of the  p53 
p53-Reactivating Molecules as Research Tools and Anticancer Drugs
p53-Reactivating Molecules as Research Tools and Anticancer Drugs
Grinkevich, Vera V.; Warnecke, Andreas; Selivanova, Galina
tumor suppressor function in cancers by small ...
... point mutation of TP53 or through disruption of  p53 
p53 in Head and Neck Cancer
p53 in Head and Neck Cancer
Roh, Jong-Lyel; Koch, Wayne M.
protein function as a consequence of oncogenic ...
... tumor suppressor in multicellular organisms,  p53 
p53
p53
Menendez, Daniel; Nguyen, Thuy-Ai; Resnick, Michael A.; Anderson, Carl W.
is one of the most intensively studied human ...
... The  p53 
p53 at the Crossroads Between Stress Response Signaling and Tumorigenesis: From Molecular Mechanisms to Therapeutic Opportunities
p53 at the Crossroads Between Stress Response Signaling and Tumorigenesis: From Molecular Mechanisms to Therapeutic Opportunities
Giono, Luciana E.; Ladelfa, M. Fátima; Monte, Martín
tumor suppressor is a transcription factor that ...
... Most tumors inactivate the  p53 
Mutant p53-Driven Tumorigenesis
Mutant p53-Driven Tumorigenesis
Terzian, Tamara; Lozano, Guillermina
tumor suppressor pathway via single nucleotide ...
... of the Forkhead box (Fox; Sect. 10.9.3) and  P53 
Other Major Types of Signaling Mediators
Other Major Types of Signaling Mediators
Thiriet, Marc
families (Sect. 10.9.4; Table 10.1). Other ...
... tumor suppressor in multicellular organisms,  p53 
p53
p53
Alexieva-Botcheva, Krassimira; Anderson, Carl W.
arguably is one of the most intensively studied ...
... Mutations in the TP53 gene or the  p53 
p53 Pathway Alterations in Brain Tumors
p53 Pathway Alterations in Brain Tumors
Yin, Shaoman; Van Meir, Erwin G.
pathway are required for the formation of many ...
...  p53 
Activation of the p53 Tumor Suppressor and its Multiple Roles in Cell Cycle and Apoptosis
Activation of the p53 Tumor Suppressor and its Multiple Roles in Cell Cycle and Apoptosis
Giono, Luciana E.; Manfredi, James J.
is a widely conserved tumor suppressor protein ...
... mediate and regulate tumor suppression exerted by  p53 
The p53/microRNA Network in Cancer: Experimental and Bioinformatics Approaches
The p53/microRNA Network in Cancer: Experimental and Bioinformatics Approaches
Hünten, Sabine; Siemens, Helge; Kaller, Markus; Hermeking, Heiko
. ...
... pathways or cell cycle arrest. High frequency of  p53 
Sentinel Gene Within Cell Territory and Molecular Platforms in Cancer: Methylation Diversity of p53 Gene in Brain Tumors
Sentinel Gene Within Cell Territory and Molecular Platforms in Cancer: Methylation Diversity of p53 Gene in Brain Tumors
Mehdipour, Parvin; Karami, Fatemeh
gene aberrations in various types of cancer has ...
... The  p53 
p53
p53
Tsai, Wen-Wei; Barton, Michelle Craig
tumor suppressor is well known as the major ...
... Tumor suppressor  p53 
The Role of Tumor Suppressor p53 in the Antioxidant Defense and Metabolism
The Role of Tumor Suppressor p53 in the Antioxidant Defense and Metabolism
Budanov, Andrei V.
is inactivated in most cancers and the critical ...
... are redundant and deeply interconnected. The  p53 
TP53: Coordinator of the Processes That Underlie the Hallmarks of Cancer
TP53: Coordinator of the Processes That Underlie the Hallmarks of Cancer
Hainaut, Pierre
protein, encoded by the TP53 tumor suppressor ...
...  p53 
Senescence Regulation by the p53 Protein Family
Senescence Regulation by the p53 Protein Family
Qian, Yingjuan; Chen, Xinbin
, a guardian of the genome, exerts its tumor ...
... of mutant forms of the tumour suppressor  p53 
Upstream Targets in the p53 Pathway
Upstream Targets in the p53 Pathway
McCarthy, Anna R.; Lain, Sonia
or wild-type ...
... recent evidence suggests that tumour suppressor  p53 
Crosstalk Between p53 and Mitochondrial Metabolism
Crosstalk Between p53 and Mitochondrial Metabolism
Itahana, Koji; Pervaiz, Shazib
actively participates in these communications. ...
... been shown to inactivate tumor suppressor protein  p53 
Mortalin-p53 Interaction as a Target for Liver Cancer Therapy
Mortalin-p53 Interaction as a Target for Liver Cancer Therapy
Lu, Wen-Jing; Lee, Nikki P.; Wadhwa, Renu; Luk, John M.
. ...
... The  p53 
p53: Guardian of the Metabolome
p53: Guardian of the Metabolome
Poyurovsky, Masha V.; Prives, Carol
tumor suppressor protein is critically important ...
...  p53 
Noncoding RNAs Regulating p53 and c-Myc Signaling
Noncoding RNAs Regulating p53 and c-Myc Signaling
Mei, Yide; Wu, Mian
is one of the most important tumor suppressors ...
...  p53 
Mechanisms of Mutant p53 Stabilization in Cancer
Mechanisms of Mutant p53 Stabilization in Cancer
Frum, Rebecca A.; Grossman, Steven R.
transactivates cell cycle inhibitory, apoptosis ...