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... section, a novel approach for identifying MDM2-  p53 
Development of a Mirror-Image Screening System for Chiral Natural Products
Development of a Mirror-Image Screening System for Chiral Natural Products
Noguchi, Taro
and MDMX- ...
... we focus on the regulatory module of the protein  p53 
Influence of the Stochasticity in Threshold Localization on Cell Fate in the PLDE-Model of the P53 Module
Influence of the Stochasticity in Threshold Localization on Cell Fate in the PLDE-Model of the P53 Module
Ochab, Magdalena; Swierniak, Andrzej; Klamka, Jerzy; Puszynski, Krzysztof
, which is responsible for cell responses to DNA ...
... CRE-mediated flox activity to render mice  p53 
Defining the Pathways of Urogenital Schistosomiasis-Associated Urothelial Carcinogenesis through Transgenic and Bladder Wall Egg Injection Models
Defining the Pathways of Urogenital Schistosomiasis-Associated Urothelial Carcinogenesis through Transgenic and Bladder Wall Egg Injection Models
Mbanefo, Evaristus C.; Hsieh, Michael H.
haploinsufficient before challenging them with ...
... role for G-quadruplex motifs has been found for  p53 
Targeting RNA G-Quadruplexes for Potential Therapeutic Applications
Targeting RNA G-Quadruplexes for Potential Therapeutic Applications
Pandey, Satyaprakash; Agarwala, Prachi; Maiti, Souvik
mRNA wherein G-quadruplex structure interacts ...
... with molecular disease targets of AD, namely,  P53 
Computational Nanotechnology: A Tool for Screening Therapeutic Nanomaterials Against Alzheimer’s Disease
Computational Nanotechnology: A Tool for Screening Therapeutic Nanomaterials Against Alzheimer’s Disease
Navanietha Krishnaraj, R.; Samanta, Dipayan; Sani, Rajesh K.
kinase recepto ...
... 2 (Chk2). Together, these kinases activate the  p53 
Simulation Analysis of the Homologous Recombination Repair Distribution over the Cell Cycle
Simulation Analysis of the Homologous Recombination Repair Distribution over the Cell Cycle
Kurpas, Monika; Puszynski, Krzysztof
transcription factor and have a suppressive ...
... neuroendocrine tumors. An animal model inducing  p53 
Precursor and Preinvasive Lesions
Precursor and Preinvasive Lesions
Borczuk, Alain C.
loss and RB loss in epithelial cells induced ...
... main downstream transducers are Chk1, Chk2, and  p53 
Noncoding RNAs in DNA Damage Response: Opportunities for Cancer Therapeutics
Noncoding RNAs in DNA Damage Response: Opportunities for Cancer Therapeutics
Arjumand, Wani; Asiaf, Asia; Ahmad, Shiekh Tanveer
, which regulate several substrate effectors and ...
... labeling of activated caspase 3 and activated  p53 
Human-Derived Neurons and Neural Progenitor Cells in High Content Imaging Applications
Human-Derived Neurons and Neural Progenitor Cells in High Content Imaging Applications
Harrill, Joshua A.
[43]. ...
... between high-grade and low-grade lymphoma.  p53 
Markers to Assist the Diagnosis of Dysplasia and Malignant Transformation
Markers to Assist the Diagnosis of Dysplasia and Malignant Transformation
Tuffaha, Muin S. A.; Guski, Hans; Kristiansen, Glen
: p53p53 is a nuclear phosphoprotein encoded by ...
... Cytokeratin profile, p63, CEA, PAX-8, PAX-2, p16,  p53 
Markers and Immunoprofile of Tumors of Female Reproductive Organs
Markers and Immunoprofile of Tumors of Female Reproductive Organs
Tuffaha, Muin S. A.; Guski, Hans; Kristiansen, Glen
, HPV, and steroid hormone receptors. ...
... displaying diffuse nuclear immunoreactivity for  P53 
Rare Papillary Thyroid Carcinomas
Rare Papillary Thyroid Carcinomas
Cameselle-Teijeiro, José M.; Eloy, Catarina; Amendoeira, Isabel; Soares, Paula; Caneiro-Gómez, Javier; Melo, Miguel; Sobrinho-Simões, Manuel
. ...
... presentation E6 Viral oncogene. Inactivates  p53 
Fundamental Biology of Human Papillomaviruses
Fundamental Biology of Human Papillomaviruses
Lambie, Meghan; Bratman, Scott V.
. ...
... pathways, the TGF $$\beta $$ β /SMAD and  p53 
Information Flow in a Mammalian Signal Transduction Pathway
Information Flow in a Mammalian Signal Transduction Pathway
Benary, Manuela; Nolis, Ilias; Blüthgen, Nils; Loewer, Alexander
networks. ...
... immunoreactivity for three of these markers (  p53 
Pancreas and Biliary Tract
Pancreas and Biliary Tract
Lin, Fan; Liu, Haiyan; Zhang, Jun
, CEA, IMP3 IMP3 (KOC) ) is usually not observed ...
... be checked by probing for the following proteins:  p53 
Identification of E6/E7-Dependent MicroRNAs in HPV-Positive Cancer Cells
Identification of E6/E7-Dependent MicroRNAs in HPV-Positive Cancer Cells
Honegger, Anja; Schilling, Daniela; Sültmann, Holger; Hoppe-Seyler, Karin; Hoppe-Seyler, Felix
and p21 Human papillomaviruses (HPVs) (E6 ...
... staining and a moderate-to-strong expression of  p53 
Uterine Sarcomas and Atypical Smooth-Muscle Tumors: Clinic, Diagnostics and Appropriate Surgical Therapy
Uterine Sarcomas and Atypical Smooth-Muscle Tumors: Clinic, Diagnostics and Appropriate Surgical Therapy
Köhler, Günter; Zygmunt, Marek T.
and p16 [50, 61, 213]. ...
... (SASP) [12]. It is well accepted that the  p53 
Diabetes and Adipocyte Dysfunction
Diabetes and Adipocyte Dysfunction
Yoshida, Yohko; Shimizu, Ippei; Minamino, Tohru
/p21 and p16/Rb signaling pathways have central ...
... positive regulators of autophagy. As shown here,  p53 
Cyclin D1, Metabolism, and the Autophagy-Senescence Balance
Cyclin D1, Metabolism, and the Autophagy-Senescence Balance
Valenzuela, Claudio; Brown, Nelson E.
can also regulate autophagy, a function that ...
... and cytokeratin (CAM5.2) staining is rare.  p53 
Histopathology of Primary Tumors of the Central Nervous System
Histopathology of Primary Tumors of the Central Nervous System
Adesina, Adekunle M.
immunoreactivity may be seen in about one-half of ...
... (CTNNB1) Up Up Un-change Up Myc (MYC) Up Up Up Up  P53 
Endogenous Molecular-Cellular Network Cancer Theory: A Systems Biology Approach
Endogenous Molecular-Cellular Network Cancer Theory: A Systems Biology Approach
Wang, Gaowei; Yuan, Ruoshi; Zhu, Xiaomei; Ao, Ping
(TP53) Up Down Up Down TGF-β (TGFB2) Up Up Up Up ...
... cyclin D1(T286A)-Cdk4 results in high levels of  p53 
D-Type Cyclins and Gene Transcription
D-Type Cyclins and Gene Transcription
Sante, Gabriele; Casimiro, Mathew C.; Li, Zhiping; Ertel, Adam; Tompa, Peter; Pestell, Richard G.
methylation and a reduction in ...
... ductal hyperplasia WHO World Health Organization   
Breast
Breast
Liu, Haiyan; Lin, Fan; Zhang, Jun
...
... for Example 7.3 Cancer Total No Yes Count Count  P53 
Multivariate Analysis
Multivariate Analysis
Momeni, Amir; Pincus, Matthew; Libien, Jenny
No PTEN No PIK3CA No 7 3 10 Yes 3 3 6 Yes PIK3CA ...
... influences. Using the TGF $$\beta $$ β and  p53 
Introduction
Introduction
Bossert, Martin
pathway as additional paradigms, we ...