Snippet Search

Searching 12,329,257 documents.
Discover how a particular term or phrase is used in scientific literature

Showing 1 to 25 of 3702 matching articles

Results per page:

... tumor suppressor in multicellular organisms,  p53 
p53
p53
Alexieva-Botcheva, Krassimira; Anderson, Carl W.
arguably is one of the most intensively studied ...
... of ING proteins is their cooperation with  p53 
Regulation of p53 by ING family members in suppression of tumor initiation and progression
Regulation of p53 by ING family members in suppression of tumor initiation and progression
Jafarnejad, Seyed Mehdi; Li, Gang
tumor suppressor protein in tumor suppression. ...
... caused by the expression of BCR-ABL. Loss of  p53 
Increased acetylation of lysine 317/320 of p53 caused by BCR-ABL protects from cytoplasmic translocation of p53 and mitochondria-dependent apoptosis in response to DNA damage
Increased acetylation of lysine 317/320 of p53 caused by BCR-ABL protects from cytoplasmic translocation of p53 and mitochondria-dependent apoptosis in response to DNA damage
Kusio-Kobialka, Monika; Wolanin, Kamila; Podszywalow-Bartnicka, Paulina; Sikora, Ewa; Skowronek, Krzysztof; McKenna, Sharon L.; Ghizzoni, Massimo; Dekker, Frank J.; Piwocka, Katarzyna
has not been implicated as important for the ...
... been shown to inactivate tumor suppressor protein  p53 
Mortalin-p53 Interaction as a Target for Liver Cancer Therapy
Mortalin-p53 Interaction as a Target for Liver Cancer Therapy
Lu, Wen-Jing; Lee, Nikki P.; Wadhwa, Renu; Luk, John M.
. ...
... in breast cancer, we identified IBP was a novel  p53 
Interferon regulatory factor 4 binding protein is a novel p53 target gene and suppresses cisplatin-induced apoptosis of breast cancer cells
Interferon regulatory factor 4 binding protein is a novel p53 target gene and suppresses cisplatin-induced apoptosis of breast cancer cells
Yang, Mingzhen; Yuan, Fang; Li, Peng; Chen, Zhongjiao; Chen, An; Li, Shuhui; Hu, Chuanmin
target gene. ...
... oxygen species during wound repair responses.  p53 
SPRR2A enhances p53 deacetylation through HDAC1 and down regulates p21 promoter activity
SPRR2A enhances p53 deacetylation through HDAC1 and down regulates p21 promoter activity
Mizuguchi, Yoshiaki; Specht, Susan; Lunz, John G, III; Isse, Kumiko; Corbitt, Natasha; Takizawa, Toshihiro; Demetris, Anthony J
is also widely recognized as the node in cellular ...
... The tumor suppressor  p53 
PDCD5 interacts with p53 and functions as a positive regulator in the p53 pathway
PDCD5 interacts with p53 and functions as a positive regulator in the p53 pathway
Xu, Lanjun; Hu, Jing; Zhao, Yuanbo; Hu, Jia; Xiao, Juan; Wang, Yanming; Ma, Dalong; Chen, Yingyu
is at the hub of cellular signaling networks that ...
... (CD71, CARM1, PI3KCA&TK1), P-cadherin,  p53 
ESP Abstracts 2012
ESP Abstracts 2012
and with lower levels of ER expression and ...
... The  p53 
Targeting the MDM2-p53 Protein-Protein Interaction for New Cancer Therapeutics
Targeting the MDM2-p53 Protein-Protein Interaction for New Cancer Therapeutics
Wang, Shaomeng; Zhao, Yujun; Bernard, Denzil; Aguilar, Angelo; Kumar, Sanjeev
tumor suppressor protein is a transcriptional ...
... Lymphomas frequently retain wild-type (wt)  p53 
HDM2 antagonist MI-219 (spiro-oxindole), but not Nutlin-3 (cis-imidazoline), regulates p53 through enhanced HDM2 autoubiquitination and degradation in human malignant B-cell lymphomas
HDM2 antagonist MI-219 (spiro-oxindole), but not Nutlin-3 (cis-imidazoline), regulates p53 through enhanced HDM2 autoubiquitination and degradation in human malignant B-cell lymphomas
Sosin, Angela M; Burger, Angelika M; Siddiqi, Aisha; Abrams, Judith; Mohammad, Ramzi M; Al-Katib, Ayad M
function but overexpress HDM2, thereby ...
... Background In HPV infected cells  p53 
Human papillomavirus 18 E6 inhibits phosphorylation of p53 expressed in HeLa cells
Human papillomavirus 18 E6 inhibits phosphorylation of p53 expressed in HeLa cells
Ajay, Amrendra K; Meena, Avtar S; Bhat, Manoj K
function is abrogated by E6 and even ectopically ...
... All ATLL cases are believed to have reduced  p53 
Wip1 and p53 contribute to HTLV-1 Tax-induced tumorigenesis
Wip1 and p53 contribute to HTLV-1 Tax-induced tumorigenesis
Zane, Linda; Yasunaga, Junichiro; Mitagami, Yu; Yedavalli, Venkat; Tang, Sai-Wen; Chen, Chia-Yen; Ratner, Lee; Lu, Xiongbin; Jeang, Kuan-Teh
activity although only a minority of ATLLs have ...
... a phase I clinical trial. Enhancement of  p53 
Novel histone deacetylase inhibitor CG200745 induces clonogenic cell death by modulating acetylation of p53 in cancer cells
Novel histone deacetylase inhibitor CG200745 induces clonogenic cell death by modulating acetylation of p53 in cancer cells
Oh, Eun-Taex; Park, Moon-Taek; Choi, Bo-Hwa; Ro, Seonggu; Choi, Eun-Kyung; Jeong, Seong-Yun; Park, Heon Joo
acetylation by HDAC inhibitors induces cell cycle ...
... In this study, we identified eight mouse  p53 
Splicing of mouse p53 pre-mRNA does not always follow the “first come, first served” principle and may be influenced by cisplatin treatment and serum starvation
Splicing of mouse p53 pre-mRNA does not always follow the “first come, first served” principle and may be influenced by cisplatin treatment and serum starvation
Yang, Min; Wu, Jack; Wu, Si-hung; Bi, An-ding; Liao, D. Joshua
transcripts that retained one or more of introns ...
... Two such pathways are those involving Hes1 and  p53 
Influence of the Nuclear Membrane, Active Transport, and Cell Shape on the Hes1 and p53–Mdm2 Pathways: Insights from Spatio-temporal Modelling
Influence of the Nuclear Membrane, Active Transport, and Cell Shape on the Hes1 and p53–Mdm2 Pathways: Insights from Spatio-temporal Modelling
Sturrock, Marc; Terry, Alan J.; Xirodimas, Dimitris P.; Thompson, Alastair M.; Chaplain, Mark A. J.
–Mdm2, both of which are implicated in cancer. ...
... The tumor suppressor  p53 
p53-dependent pathways in neurite outgrowth and axonal regeneration
p53-dependent pathways in neurite outgrowth and axonal regeneration
Giovanni, Simone; Rathore, Khizr
is a multifunctional sensor of a number of ...
... Introduction Pre-clinical data suggest  p53 
Prognostic and predictive value of TP53mutations in node-positive breast cancer patients treated with anthracycline- or anthracycline/taxane-based adjuvant therapy: results from the BIG 02-98 phase III trial
Prognostic and predictive value of TP53mutations in node-positive breast cancer patients treated with anthracycline- or anthracycline/taxane-based adjuvant therapy: results from the BIG 02-98 phase III trial
Fernández-Cuesta, Lynnette; Oakman, Catherine; Falagan-Lotsch, Priscila; Smoth, Ke-seay; Quinaux, Emmanuel; Buyse, Marc; Dolci, M Stella; Azambuja, Evandro De; Hainaut, Pierre; Dell'Orto, Patrizia; Larsimont, Denis; Francis, Prudence A; Crown, John; Piccart-Gebhart, Martine; Viale, Giuseppe; Leo, Angelo Di; Olivier, Magali
-dependent anthracycline-induced apoptosis and ...
... relationship between mitochondrial dysfunction,  p53 
The globular heads of the C1q receptor regulate apoptosis in human cervical squamous carcinoma cells via a p53-dependent pathway
The globular heads of the C1q receptor regulate apoptosis in human cervical squamous carcinoma cells via a p53-dependent pathway
Chen, Zheng-lin; Gu, Ping-qing; Liu, Kangsheng; Su, Ya-juan; Gao, Ling-juan
status and gC1qR expression and the regulation of ...
... Tumor suppressor protein  p53 
General Introduction
General Introduction
Kamada, Rui
plays a central role in maintaining genomic ...
... in pancreatic cancer cells with different  p53 
Mesothelin regulates growth and apoptosis in pancreatic cancer cells through p53-dependent and -independent signal pathway
Mesothelin regulates growth and apoptosis in pancreatic cancer cells through p53-dependent and -independent signal pathway
Zheng, Chunning; Jia, Wei; Tang, Yong; Zhao, HuiLiang; Jiang, Yingsheng; Sun, Shaochuan
status and to explore its signal pathway. ...
... The retinoblastoma (RB) and  p53 
Roles of p53 and pRB Tumor Suppressor Networks in Human Cancer: Insight from Studies in the Engineered Mouse
Roles of p53 and pRB Tumor Suppressor Networks in Human Cancer: Insight from Studies in the Engineered Mouse
Sage, Julien; Attardi, Laura; Dyke, Terry
tumor suppressor genes were identified more than ...
... induces signaling pathways mediated by the ATM,  p53 
ATM mediates interdependent activation of p53 and ERK through formation of a ternary complex with p-p53 and p-ERK in response to DNA damage
ATM mediates interdependent activation of p53 and ERK through formation of a ternary complex with p-p53 and p-ERK in response to DNA damage
Heo, Jee-In; Oh, Soo-Jin; Kho, Yoon-Jung; Kim, Jeong-Hyeon; Kang, Hong-Joon; Park, Seong-Hoon; Kim, Hyun-Seok; Shin, Jong-Yeon; Kim, Min-Ju; Kim, Minju; Kim, Sung Chan; Park, Jae-Bong; Kim, Jaebong; Lee, Jae-Yong
and ERK proteins, but the interactions between ...
... Roles of  p53 
Characterization of the tilapia p53 gene and its role in chemical-induced apoptosis
Characterization of the tilapia p53 gene and its role in chemical-induced apoptosis
Mai, Wei-jun; Liu, Peng; Wang, Weina
in mammals have been extensively studied but ...
... underlying the non-apoptotic function of  p53 
Driving Apoptosis-relevant Proteins Toward Neural Differentiation
Driving Apoptosis-relevant Proteins Toward Neural Differentiation
Solá, Susana; Aranha, Márcia M.; Rodrigues, Cecília M. P.
, caspases, and Bcl-2 family members during ...
... Purpose The human tumour suppressor protein  p53 
Therapeutic reactivation of mutant p53 protein by quinazoline derivatives
Therapeutic reactivation of mutant p53 protein by quinazoline derivatives
Sutherland, Hamish S.; Hwang, In Young; Marshall, Elaine S.; Lindsay, Brent S.; Denny, William A.; Gilchrist, Catherine; Joseph, Wayne R.; Greenhalgh, Debra; Richardson, Emma; Kestell, Philip; Ding, Angela; Baguley, Bruce C.
is mutated in nearly half of human tumours and ...

Subject

(see all 336)

Country

(see all 92)

Publication Type


Publisher