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...  p53 
Isolation of p53 Inhibitors by Screening Chemical Libraries in Cell-Based Readout System
Isolation of p53 Inhibitors by Screening Chemical Libraries in Cell-Based Readout System
Gudkov, Andrei; Komarova, Elena
is a key mediator of cell response to a variety ...
...  p53 
In Vivo Footprinting and DNA Affinity Chromatography for Analysis of p53 DNA Binding Ability
In Vivo Footprinting and DNA Affinity Chromatography for Analysis of p53 DNA Binding Ability
Molina, Maria Patricia; Cain, Christine; Bargonetti, Jill
is a sequence-specific DNA binding protein. ...
... The  p53 
Clinical Implications of p53 Mutations in Lung Cancer
Clinical Implications of p53 Mutations in Lung Cancer
Campling, Barbara G.; El-Deiry, Wafik S.
tumor-suppressor gene plays a crucial role in the ...
... technology has been recently adopted to study  p53 
Signaling to p53
Signaling to p53
Craig, Ashley L.; Bray, Susan E.; Finlan, Lee E.; Kernohan, Neil M.; Hupp, Ted R.
phosphorylation both in vivo and in vitro. ...
... human cancers, which can occur independent of  p53 
Status of p53 phosphorylation and function in sensitive and resistant human cancer models exposed to platinum-based DNA damaging agents
Status of p53 phosphorylation and function in sensitive and resistant human cancer models exposed to platinum-based DNA damaging agents
Mujoo, Kalpana; Watanabe, Masayuki; Nakamura, Junichi; Khokhar, Abdul R.; Siddik, Zahid H.
gene status; however, the presence of wild-type ...
... Background The  p53 
Tobacco, alcohol, and p53 overexpression in early colorectal neoplasia
Tobacco, alcohol, and p53 overexpression in early colorectal neoplasia
Terry, Mary Beth; Neugut, Alfred I; Mansukhani, Mahesh; Waye, Jerome; Harpaz, Noam; Hibshoosh, Hanina
tumor suppressor gene is commonly mutated in ...
... studies that the absence in cancer cells of the  p53 
Radiation induces p53-dependent cell apoptosis in bladder cancer cells with wild-type-p53 but not in p53-mutated bladder cancer cells
Radiation induces p53-dependent cell apoptosis in bladder cancer cells with wild-type-p53 but not in p53-mutated bladder cancer cells
Hinata, Nobuyuki; Shirakawa, Toshiro; Zhang, Zhujun; Matsumoto, Akira; Fujisawa, Masato; Okada, Hiroshi; Kamidono, Sadao; Gotoh, Akinobu
tumor suppressor gene, mutations of which are ...
... type 5 targets the tumor suppressor protein  p53 
Interaction of p53 with the Adenovirus E1B-55 kDa Protein
Interaction of p53 with the Adenovirus E1B-55 kDa Protein
Roth, Judith; Dobbelstein, Matthias
. ...
... The  p53 
Lung-Specific Expression of Mutant p53 as Mouse Model for Lung Cancer
Lung-Specific Expression of Mutant p53 as Mouse Model for Lung Cancer
Tchou-Wong, Kam-Meng; Rom, William N.
tumor suppressor gene is the most commonly ...
... The  p53 
Modulation of multidrug resistance-associated protein 1 (MRP1) by p53 mutant in Saos-2 cells
Modulation of multidrug resistance-associated protein 1 (MRP1) by p53 mutant in Saos-2 cells
Tsang, Wing-Pui; Chau, Sophia P. Y.; Fung, Kwok-Pui; Kong, Siu-Kai; Kwok, Tim-Tak
tumor suppressor gene is one of the most ...
... ester transfer of ubiquitin molecules. Wild-type  p53 
Stability and Ubiquitination of the Tumor Suppressor Protein p53
Stability and Ubiquitination of the Tumor Suppressor Protein p53
Jardine, Lesley J.; Maki, Carl G.
is a tumor suppressor protein and potent ...
... cancer mutants of the transcription factor  p53 
Genetic Strategies in Saccharomyces cerevisiae to Study Human Tumor Suppressor Genes
Genetic Strategies in Saccharomyces cerevisiae to Study Human Tumor Suppressor Genes
Kobayashi, Takahiko; Wang, Ting; Qian, Hua; Brachmann, Rainer K.
with numerous binding sites of downstream target ...
... is involved in studying the function of the  p53 
Induction of p53 Expression and Function by Estrogen in Osteoblasts
Induction of p53 Expression and Function by Estrogen in Osteoblasts
Bovenkerk, S.; Lanciloti, N.; Chandar, N.
tumor suppressor gene in osteoblast ...
... The  p53 
Flow Cytometric Analysis of p53-Induced Apoptosis
Flow Cytometric Analysis of p53-Induced Apoptosis
Berger, Michael; Haupt, Ygal
protein is a key player in the cellular response ...
... HIF-1α protein accumulation is associated with  p53 
Tumor Deprivation of Oxygen and Tumor Suppressor Gene Function
Tumor Deprivation of Oxygen and Tumor Suppressor Gene Function
Yun, Zhong; Giaccia, Amato J.
mutation and increased proliferation (15). ...
... growth of various malignant tumors. The Bcl-2 and  p53 
Prognostic significance of Bcl-2 and p53 expression in gastric cancer
Prognostic significance of Bcl-2 and p53 expression in gastric cancer
Lee, Hyeon Kook; Lee, Hye Seung; Yang, Han-Kwang; Kim, Woo Ho; Lee, Kuhn Uk; Choe, Kuk Jin; Kim, Jin-Pok
are closely linked in the regulation of ...
... many controversial reports about the effect of  p53 
p21WAF1/CIP1 is more effective than p53 in growth suppression of mouse renal carcinoma cell line Renca in vitro and in vivo
p21WAF1/CIP1 is more effective than p53 in growth suppression of mouse renal carcinoma cell line Renca in vitro and in vivo
Kralj, Marijeta; Pavelić, Jasminka
and p21WAF1/CIP1 overexpression in different ...
... the usefulness of determination of HER2,  p53 
Coexistence of HER2 over-expression and p53 protein accumulation is a strong prognostic molecular marker in breast cancer
Coexistence of HER2 over-expression and p53 protein accumulation is a strong prognostic molecular marker in breast cancer
Yamashita, Hiroko; Nishio, Mariko; Toyama, Tatsuya; Sugiura, Hiroshi; Zhang, Zhenhuan; Kobayashi, Shunzo; Iwase, Hirotaka
, and Ki67 proliferation indices using ...
... involved in human cancers is the tumor suppressor  p53 
Identification of p53 Target Genes by Fluorescent Differential Display
Identification of p53 Target Genes by Fluorescent Differential Display
Stein, Susanne; Cho, Yong-Jig; Jackson, Roger S., II; Liang, Peng
. ...
... transactivation and transrepression properties of  p53 
Transactivation and Transrepression Studies with p53
Transactivation and Transrepression Studies with p53
Scian, Mariano J.; Frum, Rebecca; Deb, Swati Palit; Deb, Sumitra
(as well as p63 and p73). ...
... We describe a method for purifying recombinant  p53 
Purification of Recombinant p53 from Sf9 Insect Cells
Purification of Recombinant p53 from Sf9 Insect Cells
Sun, Xiu Zhu; Nguyen, John; Momand, Jamil
from baculovirus infected cells in one step by ...
... the FISH method with locus-specific probes for  p53 
Investigation of c-myc and p53 Gene Alterations in the Tumor and Surgical Borderline Tissues of NSCLC and Effects on Clinicopathologic Behavior: By the FISH Technique
Investigation of c-myc and p53 Gene Alterations in the Tumor and Surgical Borderline Tissues of NSCLC and Effects on Clinicopathologic Behavior: By the FISH Technique
Yakut, T.; Egeli, U.; Gebitekin, C.
tumor suppressor gene and c-myc oncogene and ...
... examples, we describe results obtained on the  p53 
Functional Analysis of Tumor Suppressor Genes in Mice
Functional Analysis of Tumor Suppressor Genes in Mice
Jones, Stephen N.; Donehower, Lawrence A.
-deficient mouse, in part because of its ...
... of the use of differential display to identify  p53 
Differential Display Techniques to Identify Tumor Suppressor Gene Pathways
Differential Display Techniques to Identify Tumor Suppressor Gene Pathways
Biade, Siham; Murphy, Maureen E.
target genes, as well as secondary tumor ...
... Purpose The susceptibility of male  p53 
High susceptibility of nullizygous p53 knockout mice to colorectal tumor induction by 1,2-dimethylhydrazine
High susceptibility of nullizygous p53 knockout mice to colorectal tumor induction by 1,2-dimethylhydrazine
Sakai, Hiroki; Tsukamoto, Tetsuya; Yamamoto, Masami; Shirai, Norimitsu; Iidaka, Takeshi; Hirata, Akihiro; Yanai, Tokuma; Masegi, Toshiaki; Donehower, Lawrence A.; Tatematsu, Masae
nullizygote (-/-), heterozygote (+/-), and ...