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... devastating neurologic diseases. Tumor Suppressor  p53 
p53 Induction Is a Marker of Neuronal Apoptosis in the Central Nervous System
p53 Induction Is a Marker of Neuronal Apoptosis in the Central Nervous System
Sakhi, Shahin; Schreiber, Steven S.
: Cell Cycle Arrest vs Cell Death Several lines ...
... recombinant protein from the column. Recombinant  p53 
Detection and Isolation of Recombinant Proteins from Mammalian Cells by Immunoaffinity Chromatography: p53
Detection and Isolation of Recombinant Proteins from Mammalian Cells by Immunoaffinity Chromatography: p53
Momand, Jamil; Sepehrnia, Bahman
is used to illustrate this methodology. ...
... and cloning of the retinoblastoma (Rb) and  p53 
Methods for Cancer Gene Therapy Using Tumor Suppressor Genes
Methods for Cancer Gene Therapy Using Tumor Suppressor Genes
Zhang, Wei-Wei; Roth, Jack A.
genes, the study of what are now called tumor ...
...  p53 
p53 nuclear immunoreactivity as a predictor of response and outcome following chemotherapy for metastatic bladder cancer
p53 nuclear immunoreactivity as a predictor of response and outcome following chemotherapy for metastatic bladder cancer
Sengeløv, L.; Horn, T.; Steven, K.
nuclear immunoreactivity was determined in ...
... show immunohistochemical positivity for  p53 
Accumulation of wild-type p53 in astrocytomas is associated with increased p21 expression
Accumulation of wild-type p53 in astrocytomas is associated with increased p21 expression
Ono, Yasuhiro; Tamiya, T.; Ichikawa, Tomotsugu; Matsumoto, Kengo; Furuta, Tomohisa; Ohmoto, Takashi; Akiyama, Kosuke; Seki, Shuji; Ueki, Keisuke; Louis, David N.
protein but lack ...
...  Mutations of the  p53 
Molecular and immunohistochemical analysis of p53 mutations in scrapings and tissue from preinvasive and invasive breast cancer
Molecular and immunohistochemical analysis of p53 mutations in scrapings and tissue from preinvasive and invasive breast cancer
Lisboa, B. W.; Vogtländer, Sabine; Gilster, Tobias; Riethdorf, Lutz; Milde-Langosch, Karin; Löning, Thomas
gene appear to be one of the most common ...
... for alterations of the tumour suppressor gene  p53 
p53 Alterations in thymic epithelial tumours
p53 Alterations in thymic epithelial tumours
Weirich, G.; Schneider, P.; Fellbaum, C.; Brauch, H.; Nathrath, W.; Scholz, M.; Präuer, H.; Höfler, H.
using immunohistochemistry (antibodies D0-1 and ...
... in thymic epithelial tumors the tumor suppressor  p53 
p53-Alterations in Thymic Epithelial Tumors
p53-Alterations in Thymic Epithelial Tumors
Weirich, G.; Schneider, P.; Fellbaum, C.; Brauch, H.; Nathrath, W.; Scholz, M.; Präuer, H.; Höfler, H.
was analysed whose alterations are known to be a ...
... analyzep53 gene mutations and the expression of  p53 
p53 gene mutations and expression of p53 and mdm2 proteins in invasive breast carcinoma
p53 gene mutations and expression of p53 and mdm2 proteins in invasive breast carcinoma
Günther, T.; Schneider-Stock, R.; Ryš, J.; Niezabitowski, A.; Roessner, A.
and mdm2 proteins in 31 randomly selected ...
... Zusammenfassung Veränderungen des  p53 
Immunhistochemische Expression des p53-Proteins in Plattenepithelkarzinomen und normalem und dysplastischem Epithel der Mundhöhle
Immunhistochemische Expression des p53-Proteins in Plattenepithelkarzinomen und normalem und dysplastischem Epithel der Mundhöhle
Piffkó, J.; Bánkfalvi, Á.
-Tumor-suppressorsystems sind sowohl auf ...
... Summary Overexpression of the  p53 
p53 Overexpression and Thymoma Prognosis
p53 Overexpression and Thymoma Prognosis
Pich, Achille; Chiarle, Roberto; Chiusa, Luigi; Motta, Manuela; Palestro, Giorgio
protein has been retrospectively investigated in ...
...  p53 
p53 serum antibodies as prognostic indicator in head and neck cancer
p53 serum antibodies as prognostic indicator in head and neck cancer
Werner, J. A.; Gottschlich, Stefan; Folz, Benedikt J.; Goeroegh, Tibor; Lippert, Burkard M.; Maass, J.-D.; Rudert, Heinrich
antibodies are a new serological parameter of ...
... (RCC) is highly variable. Overexpression of the  p53 
p53 protein expression but not mdm-2 protein expression is associated with rapid tumor cell proliferation and prognosis in renal cell carcinoma
p53 protein expression but not mdm-2 protein expression is associated with rapid tumor cell proliferation and prognosis in renal cell carcinoma
Moch, H.; Sauter, G.; Gasser, T. C.; Buchholz, N.; Bubendorf, L.; Richter, J.; Jiang, F.; Dellas, A.; Mihatsch, M. J.
protein has been suggested as a possible ...
... (HCC) cell line, HLF, expresses only mutant-type  p53 
Wild-typep53 gene-induced morphological changes and growth suppression in hepatoma cells
Wild-typep53 gene-induced morphological changes and growth suppression in hepatoma cells
Terai, Shuji; Noma, Takafumi; Kimura, Teruaki; Nakazawa, Atsushi; Kurokawa, Fumie; Okita, Kiwamu
(mt- ...
...  Inactivation of the  p53 
DNA Aneuploidy, S-phase fraction, nuclear p53 positivity, and survival in non-small-cell lung carcinoma
DNA Aneuploidy, S-phase fraction, nuclear p53 positivity, and survival in non-small-cell lung carcinoma
Dalquen, P.; Moch, Holger; Feichter, Georg; Lehmann, M.; Solèr, Markus; Stulz, Peter; Jordan, Paul; Torhorst, Joachim; Mihatsch, Michael J.; Sauter, Guido
gene plays a key role in tumour biology, probably ...
... Our knowledges and opinions on  p53 
Nuclear Reactivity Relationship Among p53 and Some of its Downstream Proteins is Predictive of p53 Functional State
Nuclear Reactivity Relationship Among p53 and Some of its Downstream Proteins is Predictive of p53 Functional State
Tomasini, D.; Cerri, A.; Decleva, I.; Venegoni, L.; Felli, A.; Berti, E.
have radically changed since its identification. ...
... Overexpression of  p53 
Immunohistochemical determination of p53 overexpression
Immunohistochemical determination of p53 overexpression
Burkhard, F. C.; Markwalder, R.; Thalmann, G. N.; Studer, U. E.
, as determined by immunohistochemical staining ...
...  P53 
Prognostic markers for colorectal cancer: Expression of P53 and BCL2
Prognostic markers for colorectal cancer: Expression of P53 and BCL2
Pereira, Hermínia; Silva, Salete; Julião, Rui; Garcia, Palla; Perpétua, Fátima
is a tumor suppressor gene that has been ...
... common genetic alterations, K-ras mutation and  p53 
Prevalence and clinical significance of combined K-ras mutation and p53 aberration in pancreatic adenocarcinoma
Prevalence and clinical significance of combined K-ras mutation and p53 aberration in pancreatic adenocarcinoma
Dergham, Sanaa T.; Dugan, Michael C.; Kucway, Roger; Du, Wei; Kamarauskiene, Dalia S.; Vaitkevicius, Vainutis K.; Crissman, John D.; Sarkar, Fazlul H.
overexpression in pancreatic adenocarcinoma ...
... to tumour development and tumour progression.  p53 
p53 Abnormalities are rare events in neuroendocrine (Merkel cell) carcinoma of the skin
p53 Abnormalities are rare events in neuroendocrine (Merkel cell) carcinoma of the skin
Schmid, Monika; Janβen, Katharina; Dockhorn-Dworniczak, Barbara; Metze, Dieter; Zelger, Bernhard W.; Luger, Thomas A.; Schmid, Kurt W.
was investigated in a series of routinely ...
... injury. We investigated the hypothesis that the  p53 
Expression of p53 protein and p53 gene transcripts in rabbit carotid arteries after balloon denudation
Expression of p53 protein and p53 gene transcripts in rabbit carotid arteries after balloon denudation
Aoyagi, Masaru; Yamamoto, Mari; Azuma, Hiroshi; Nagashima, Goro; Niimi, Yasunari; Hirakawa, Kimiyoshi; Yamamoto, Kiyotaka
protein may play a role in regulating SMC ...
...  Immunocytochemically detectable MT and  p53 
Immunoreactive p53 and metallothionein expression in duct carcinoma in situ of the breast
Immunoreactive p53 and metallothionein expression in duct carcinoma in situ of the breast
Douglas-Jones, A. G.; Navabi, H.; Morgan, J. M.; Jasani, B.
have been found more commonly in comedo DCIS of ...
... many studies addressing astrocytomas in adults.  p53 
p53 protein in pediatric malignant astrocytomas: A study of 21 patients
p53 protein in pediatric malignant astrocytomas: A study of 21 patients
Bhattacharjee, Meena B.; Bruner, Janet M.
immunoreactivity has been usedto screen tissues ...
... have documented mutations in the tumor suppressor  p53 
Immunohistochemical localization of p53 in human thyroid neoplasms: Correlation with biological behavior
Immunohistochemical localization of p53 in human thyroid neoplasms: Correlation with biological behavior
Hosal, Sefik A.; Apel, Robyn L.; Freeman, Jeremy L.; Azadian, Abbas; Rosen, Irving B.; LiVolsi, Virginia A.; Asa, Sylvia L.
gene almost exclusively in anaplastic ...
... negative expression of P-glycoprotein and mutant  p53 
Relationship of P-glycoprotein and p53 protein to chemosensitivity in colorectal cancer
Relationship of P-glycoprotein and p53 protein to chemosensitivity in colorectal cancer
Yagi, Keiko; Kunitomo, Kazufumi; Ii, Kunio; Tashiro, Seiki
protein by immunohistochemistry on 101 human ...