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... can achieve remissions in refractory patients.  p53 
Continuous Infusion of Antisense Phosphorothioate Therapeutics
Continuous Infusion of Antisense Phosphorothioate Therapeutics
Iversen, Patrick L.; Copple, Bryan L.; Tewary, Hemant K.; Bayever, Eliel; Bishop, Michael R.
Background ...
... Summary Conclusion Anti-  p53 
The role of anti-p53-autoantibodies in pancreatic disorders
The role of anti-p53-autoantibodies in pancreatic disorders
Gansauge, Susanne; Gansauge, Frank; Negri, Giovanni; Galle, Peter; Müller, Jörg; Nüssler, Andreas K.; Poch, Bertram; Beger, Hans G.
-autoantibodies (a- ...
... adenocarcinomas for mutations in exons 5,6,7,8 of  p53 
The significance of P53 gene mutations and expressions in human colorectal tumors
The significance of P53 gene mutations and expressions in human colorectal tumors
Hua, Qian; Baoming, Yu; Xigeng, Zhou; Ruinian, Wang; Wei, Huang; Saijuan, Chen; Zhu, Chen
gene. ...
... The  p53 
A polymorphism but no mutations in the GADD45 gene in breast cancers
A polymorphism but no mutations in the GADD45 gene in breast cancers
Blaszyk, H.; Hartmann, A.; Sommer, S. S.; Kovach, J. S.
gene product is part of a pathway regulating ...
... cancer had 30 Gy radiation prior to surgery.  p53 
Thep53 gene is a potent determinant of chemosensitivity and radiosensitivity in gastric and colorectal cancers
Thep53 gene is a potent determinant of chemosensitivity and radiosensitivity in gastric and colorectal cancers
Hamada, Madoka; Fujiwara, Toshiyoshi; Hizuta, Akio; Gochi, Akira; Naomoto, Yoshio; Takakura, Norihisa; Takahashi, Kenji; Roth, Jack A.; Tanaka, Noriaki; Orita, Kunzo
mutations were detected in 4 cases of gastric ...
... growth inhibition is observed when the human  p53 
A mutation in a thioredoxin reductase homolog suppresses p53-induced growth inhibition in the fission yeastSchizosaccharomyces pombe
A mutation in a thioredoxin reductase homolog suppresses p53-induced growth inhibition in the fission yeastSchizosaccharomyces pombe
Casso, D.; Beach, D.Casso, D.; Beach, D.
tumor suppressor gene product is expressed in the ...
... was to evaluate the presence and distribution of  p53 
Comparison of benign and malignant endometrial lesions for their p53 state, using immunohistochemistry and temperature-gradient gel electrophoresis
Comparison of benign and malignant endometrial lesions for their p53 state, using immunohistochemistry and temperature-gradient gel electrophoresis
Riethdorf, L.; Begemann, C.; Riethdorf, S.; Milde-Langosch, K.; Löning, T.
alterations in pure endometrioid adenocarcinomas ...
... cancers. As a transcriptional regulator,  p53 
MDR1 expression correlates with mutantp53 expression in colorectal cancer metastases
MDR1 expression correlates with mutantp53 expression in colorectal cancer metastases
Kant, Eric; Heide, Immo; Thiede, Christian; Herrmann, Richard; Rochlitz, Christoph F.
might be involved in regulation ofMDR1 expression ...
... Zusammenfassung Mutationen des  p53 
Das Tumorsuppressorgen p53 Die theoretischen Grundlagen und ihre Bedeutung für die Pathologie
Das Tumorsuppressorgen p53 Die theoretischen Grundlagen und ihre Bedeutung für die Pathologie
Poremba, C.; Bankfalvi, A.; Dockhorn-Dworniczak, B.
-Tumorsuppressorgens lassen sich in etwa 50 % ...
... The humoral immune response to  p53 
Characterisation and clinicopathological correlates of serum anti-p53 antibodies in breast and colon cancer
Characterisation and clinicopathological correlates of serum anti-p53 antibodies in breast and colon cancer
Coomber, David; Hawkins, Nicholas J.; Clark, Michelle; Meagher, Alan; Ward, Robyn L.
was determined in 54 individuals with colon or ...
... Summary At present,  p53 
Study on the p53 protein expression in gastric cancer and precancerous lesions by flow cytometry
Study on the p53 protein expression in gastric cancer and precancerous lesions by flow cytometry
Ying, Hao; Jinkun, Zhang; Cuiqiong, Yi
gene and its product ...
... were used to study the seventh exon of the  p53 
Analysis of the cellular origin of hepatocellular carcinoma by p53 genotype
Analysis of the cellular origin of hepatocellular carcinoma by p53 genotype
He, Bin; Tang, Zhao-You; Liu, Kang-Da; Zhou, Ge
gene in 29 primary and recurrent hepatomas in ...
...  p53 
p53 Expression in four human medulloblastoma-derived cell lines
p53 Expression in four human medulloblastoma-derived cell lines
Srinivasan, Jayashree; Berger, Mitchel S.; Silber, John R.
is a tumor suppressor gene found on the short arm ...
... PURPOSE: Mutation of the  p53 
Detection of circulating anti-p53 antibodies in patients with colorectal carcinoma and the antibody's relation to clinical factors
Detection of circulating anti-p53 antibodies in patients with colorectal carcinoma and the antibody's relation to clinical factors
Shibata, Yutaka; Kotanagi, Hitoshi; Andoh, Hideaki; Koyama, Kenji; Itoh, Hideaki; Kudo, Shin -Ei
tumor suppressor gene is the most common genetic ...
... c-jun: TGCAGTCATAGAAC;jun-B: AGTTTGTAGTCGTG;  p53 
Antisense-Mediated Inhibition of Protein Synthesis
Antisense-Mediated Inhibition of Protein Synthesis
Brysch, Wolfgang; Rifai, Abdalla; Tischmeyer, Wolfgang; Schlingensiepen, Karl-Hermann
: CAACAGTGAGGGAC; erbB-2: CATGGTGC TCACTG; ...
... eines primären Bronchuskarzinoms gewählt. Nachdem  p53 
Anwendung von P53-Gen-Analysen in der thoraxchirurgischen Onkologie am Beispiel des solitären pulmonalen Rundherdes
Anwendung von P53-Gen-Analysen in der thoraxchirurgischen Onkologie am Beispiel des solitären pulmonalen Rundherdes
Kandioler, Daniela; Dekan, G.; Pasching, Eva; Langmann, F.; Mannhalter, Christine; Wolner, E.; Eckersberger, F.
-Mutationen die häufigsten tumorassoziierten ...
... prognostic significance of overexpression of  p53 
Flow cytometric examination of p53 protein in primary tumors and metastases to the liver and lymph nodes of colorectal cancer
Flow cytometric examination of p53 protein in primary tumors and metastases to the liver and lymph nodes of colorectal cancer
Kimura, Osamu; Sugamura, Kenji; Kijima, Tosihisa; Makino, Masato; Shirai, Hiroyuki; Tatebe, Shigeru; Ito, Hisao; Kaibara, Nobuaki
in cases of colorectal cancer, expression of ...
... using a panel of four different anti-  p53 
Proliferative (mib1, mdm2) versus anti-proliferative (p53) markers in head and neck cancer. An Immunohistochemical study
Proliferative (mib1, mdm2) versus anti-proliferative (p53) markers in head and neck cancer. An Immunohistochemical study
Piffkó, József; Bánkfalvi, Ágnes; Öpfner, Dietmar; Tötsch, Martin; Berens, Axel; Joos, Ulrich; Böcker, Werner; Schmid, Kurt Werner
antibodies (CM1, PAbl801, D07, PAb240), a ...
... the incidence of immunohistochemically detectable  p53 
Immunostaining of p53 protein in ovarian carcinoma: correlation with histopathological data and clinical outcome
Immunostaining of p53 protein in ovarian carcinoma: correlation with histopathological data and clinical outcome
Reles, Angela; Schmider, Annette; Press, Michael F.; Schönborn, Ines; Friedmann, Wolfgang; Huber-Schumacher, S.; Strohmeyer, Torsten; Lichtenegger, Werner
protein accumulation in epithelial ovarian ...
... of theMDM2 oncogene may lead to increasedMDM2-  p53 
Alterations of thep53, Rb andMDM2 genes in osteosarcoms
Alterations of thep53, Rb andMDM2 genes in osteosarcoms
Miller, Carl W.; Aslo, Abdulkarim; Won, Alvina; Tan, Michael; Lampkin, Beatrice; Koefflar, H. Phillip
binding resulting in inactivation ofp53 ...
... Mutations in the  p53 
The role of p53 in malignancy
The role of p53 in malignancy
Keith, F. J.; Russell, N. H.
gene are currently the most common genetic lesion ...
... been extensively characterized genetically. The  p53 
Infrequency of p53 gene mutations in ependymomas
Infrequency of p53 gene mutations in ependymomas
Fink, Karen L.; Rushing, Elisabeth J.; Schold, S. Clifford, Jr.; Nisen, Perry D.
tumor suppressor gene is frequently mutated in ...
... the cells show an increase in accumulation of  p53 
Cell-cycle arrests and p53 accumulation induced by geldanamycin in human ovarian tumour cells
Cell-cycle arrests and p53 accumulation induced by geldanamycin in human ovarian tumour cells
McIlwrath, A. J.; Brunton, V. G.; Brown, R.
protein that is maximal at 24 h after drug ...
... we analyzed genetic instability and  p53 
Microsatellite instability and mutations of p53 and TGF-RII genes in gastric cancer
Microsatellite instability and mutations of p53 and TGF-RII genes in gastric cancer
Renault, B.; Calistri, Daniele; Buonsanti, Giovanni; Nanni, Oriana; Amadori, Dino; Ranzani, Guglielmina N.
gene mutations in 40 primary gastric carcinomas. ...
... sequence for a 2-base deletion in exon 6 of the  p53 
Fluorescent Sequencing Protocols in Diagnosis
Fluorescent Sequencing Protocols in Diagnosis
Graham, Colin A.; Hill, Alison J. M.
gene (1214 de1 TT) (C) A 3-base deletion in exon ...