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... Mutational changes in the  p53 
Significance of P53 in human thyroid tumors
Significance of P53 in human thyroid tumors
Simon, Dietmar; Goretzki, Peter E.; Goreley, Victor; Ebling, Birgit; Reishaus, Ellen; Lyons, John; Haubruck, Hans; Röher, Hans D.
tumor suppressor gene are the most frequent ...
... cell nuclear antigen (PCNA) and the mutant  p53 
Association of immunohistochemical p53 tumor suppressor gene protein overexpression with prognosis in highly proliferative human mammary adenocarcinomas
Association of immunohistochemical p53 tumor suppressor gene protein overexpression with prognosis in highly proliferative human mammary adenocarcinomas
Schimmelpenning, Hendrik; Eriksson, Elina T.; Zetterberg, Anders; Auer, Gert U.
protein in routinely paraffin-embedded surgical ...
... have demonstrated alterations of the  p53 
P53 accumulation in precursor lesions and early stages of bladder cancer
P53 accumulation in precursor lesions and early stages of bladder cancer
Schmitz-Dräger, B. J.; Roeyen, C. R. C.; Grimm, M. O.; Gerharz, C. -D.; Decken, K.; Schulz, W. A.; Bültel, H.; Makri, D.; Ebert, T.; Ackermann, R.
tumor-suppressor gene in a considerable number of ...
... a study to determine whether increases in  p53 
Relationship amongp53, stage, and prognosis of large bowel cancer
Relationship amongp53, stage, and prognosis of large bowel cancer
Nathanson, S. David; Linden, Michael D.; Tender, Paul; Zarbo, Richard J.; Jacobsen, Gordon; Nelson, Lisa T.
protein in primary carcinomas of the colon or ...
... of cancers from humans contain mutations at the  p53 
The Two Amino Terminal Transforming Functions of the SV40 Large T-Antigen are Required to Overcome P53 Mediated Growth Arrest
The Two Amino Terminal Transforming Functions of the SV40 Large T-Antigen are Required to Overcome P53 Mediated Growth Arrest
Quartin, Robin S.; Levine, Arnold J.
locus1,2. ...
... Zusammenfassung. Das Produkt des  p53 
Das Tumorsuppressor-Gen p53 und seine Bedeutung für die Dermatologie
Das Tumorsuppressor-Gen p53 und seine Bedeutung für die Dermatologie
Lübbe, Jann; Kleihues, Paul; Burg, Günter
-Tumorsuppressor-Gens reguliert als ...
... such as breast cancer and cancer of the prostate,  p53 
Detection of p53 tumor-suppressor-gene protein in bladder tumors and prostate cancer: possible clinical implications
Detection of p53 tumor-suppressor-gene protein in bladder tumors and prostate cancer: possible clinical implications
Kuczyk, M. A.; Serth, J.; Hervatin, C.; Arndt, H.; Derendorf, L.; Thon, W. F.; Jonas, U.
oncoprotein overexpression indicating an ...
... mediates promotion-related changes. As altered  p53 
Effect of Specific Fatty Acids on p53 Expression in Rat Mammary Tumor Cells
Effect of Specific Fatty Acids on p53 Expression in Rat Mammary Tumor Cells
Tillotson, J. K.; Cohen, L. A.; Ronai, Z.
expression has been described in 45–55% of human ...
... The  p53 
p53 expression in human soft tissue sarcomas. Correlation with biological aggressiveness
p53 expression in human soft tissue sarcomas. Correlation with biological aggressiveness
Toffoli, G.; Perin, T.; Doglioni, C.; Frustaci, S.; Buonadonna, A.; Paoli, A.; Cernigoi, C.; Tumiotto, L.; Dall’Arche, M. G.; Boiocchi, M.
gene located at chromosome 17 p13 encodes a MW ...
... Immunohistochemical staining of  p53 
Correlation of p53 with the clinicopathologic features and prognosis of colorectal adenocarcinoma
Correlation of p53 with the clinicopathologic features and prognosis of colorectal adenocarcinoma
Suzuki, Hiroshi; Matsumoto, Koichi; Koide, Akira; Tada, Toyoji; Fujino, Ippei; Okuda, Akiko; Shigemori, Chika
was performed using an anti- ...
... from potentially oncogenic HPV types degrade  p53 
Immunohistochemical detection of p53 protein in cutaneous lesions from transplant recipients harbouring human papillomavirus DNA
Immunohistochemical detection of p53 protein in cutaneous lesions from transplant recipients harbouring human papillomavirus DNA
Pélisson, I.; Chardonnet, Y.; Euvrard, S.; Schmitt, D.
tumour suppressor gene product in vitro, we ...
... To clarify whether  p53 
Expression of p53 protein in benign epithelial hyperplasia, atypical ductal hyperplasia, non-invasive and invasive mammary carcinoma: an immunohistochemical study
Expression of p53 protein in benign epithelial hyperplasia, atypical ductal hyperplasia, non-invasive and invasive mammary carcinoma: an immunohistochemical study
Umekita, Y.; Takasaki, T.; Yoshida, H.
protein expression is involved in multistep ...
... The  p53 
Type and Frequency of p53 Mutations in Tumors of the Nervous System and Its Coverings
Type and Frequency of p53 Mutations in Tumors of the Nervous System and Its Coverings
Kleihues, P.; Ohgaki, H.; Eibl, R. H.; Reichel, M. B.; Mariani, L.; Gehring, M.; Petersen, I.; Höll, T.; Deimling, A.; Wiestler, O. D.; Schwab, M.
tumor suppressor gene encodes a nuclear ...
...  P53 
Mutations of the P53 Gene in Acute Leukemias: A Report on 207 Cases
Mutations of the P53 Gene in Acute Leukemias: A Report on 207 Cases
Preudhomme, C.; Quiquandon, I.; Jonveaux, P.; Laï, J. L.; Vanrumbeke, M.; Loucheux-Lefebvre, M. H.; Kerckaert, J. P.; Fenaux, P.
is a nuclear phosphoprotein encoded by a gene ...
... In order to evaluate the expression of  p53 
Expression of p53 protein in laryngeal squamous cell carcinoma and dysplasia: possible correlation with human papillomavirus infection and clinicopathological findings
Expression of p53 protein in laryngeal squamous cell carcinoma and dysplasia: possible correlation with human papillomavirus infection and clinicopathological findings
Gorgoulis, V.; Rassidakis, G.; Kittas, C.; Giatromanolaki, A.; Barbatis, C.; Karameris, A.
protein in 28 premalignant and 40 malignant ...
... to see whether they express wild type (wt)-  p53 
Negative effects of wild-type p53 and s-Myc on cellular growth and tumorigenicity of glioma cells
Negative effects of wild-type p53 and s-Myc on cellular growth and tumorigenicity of glioma cells
Asai, Akio; Miyagi, Yohei; Sugiyama, Akinori; Gamanuma, Michiko; Hong, Seok Il; Takamoto, Shigeru; Nomura, Kazuhiro; Matsutani, Masao; Takakura, Kintomo; Kuchino, Yoshiyuki
or mutated form (mut)- ...
... MDM2 protein is thought to bind to  p53 
Low grade amplification of MDM2 gene in a subset of human breast cancers without p53 alterations
Low grade amplification of MDM2 gene in a subset of human breast cancers without p53 alterations
Takami, Koji; Inui, Hiroki; Nagayama, Koichi; Watatani, Masahiro; Yasutomi, Masayuki; Kurahashi, Hiroki; Mori, Takesada; Takai, Shin-Ichiro; Nishisho, Isamu
tumor suppressor protein leading to inhibition ...
... To test the hypothesis that mutations in the  p53 
p53 mutations in gastric and colorectal cancers in Texas Hispanics versus Anglos
p53 mutations in gastric and colorectal cancers in Texas Hispanics versus Anglos
Schneider, B. G.; Pekkel, V.; Shelton, C. H.; Pulitzer, D. R.; Allred, D. C.; Hilsenbeck, S. G.; Hensel, C. H.; Rodríguez-Martínez, H. A.; Gutiérrez-Díaz C., M. E.
tumour suppressor gene are involved in these ...
... Accumulation of  p53 
p53 accumulation in polynuclear-giant-cells
p53 accumulation in polynuclear-giant-cells
Wiethege, T.; Müller, K. M.; Voss, B.
has been reported in nearly all malignant human ...
... of human cancers seems to be inactivation of the  p53 
p53Val135 temperature sensitive mutant suppresses growth of human breast cancer cells
p53Val135 temperature sensitive mutant suppresses growth of human breast cancer cells
Eliyahu, Daniel; Evans, Steve; Rosen, Neal; Eliyahu, Siona; Zwiebel, James; Paik, Soonmyoung; Lippman, Marc
gene, via point mutation or deletion or both; or ...
... leukemia was investigated for alterations of the  p53 
Preliminary research on the p53 gene rearrangements in the evolution of chronic myelogenous leukemia to blast crisis
Preliminary research on the p53 gene rearrangements in the evolution of chronic myelogenous leukemia to blast crisis
Jing-chun, Chen; Shu-mao, Liu; Hong-bao, Fei; Wei-long, Gong
gene by Southern blot analysis. ...
... immunohistochemical analyses, mutations in the  p53 
Analysis of p53 gene mutations in low- and high-grade astrocytomas by polymerase chain reaction-assisted single-strand conformation polymorphism and immunohistochemistry
Analysis of p53 gene mutations in low- and high-grade astrocytomas by polymerase chain reaction-assisted single-strand conformation polymorphism and immunohistochemistry
Koga, Hisashi; Zhang, Shujing; Kumanishi, Toshiro; Washiyama, Kazuo; Ichikawa, Tomio; Tanaka, Ryuichi; Mukawa, Jiro
tumor suppressor gene were examined in 19 low-and ...
... We analysed  p53 
Immunohistochemical analysis of p53 protein overexpression in liver cell dysplasia and in hepatocellular carcinoma
Immunohistochemical analysis of p53 protein overexpression in liver cell dysplasia and in hepatocellular carcinoma
Zhao, M.; Laissue, J. A.; Zimmermann, A.; Zhang, N -X.
protein immunoreactivity in hepatocellular ...
... isothiocyanate-labelled DNA probes, and for  p53 
Search for accumulation of p53 protein and detection of human papillomavirus genomes in sebaceous gland carcinoma of the eyelid
Search for accumulation of p53 protein and detection of human papillomavirus genomes in sebaceous gland carcinoma of the eyelid
Hayashi, N.; Ueno, H.; Furihata, M.; Ohtsuki, Y.
protein accumulation by immunohistochemical ...
... Zusammenfassung Mutationen und Deletionen des  p53 
p53-Antionkogenpeptide als potentielle Tumorvakzine
p53-Antionkogenpeptide als potentielle Tumorvakzine
Leder, G. H.; Storkus, W. J.; Stuber, G.; Modrow, S.; Lotzke, M. T.
Tumorsuppressorgens sind die häufigsten ...