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... [14]. NOTCH1 mutation in conjunction with loss of  P53 
Phase I trial of weekly MK-0752 in children with refractory central nervous system malignancies: a pediatric brain tumor consortium study
Phase I trial of weekly MK-0752 in children with refractory central nervous system malignancies: a pediatric brain tumor consortium study
Hoffman, Lindsey M.; Fouladi, Maryam; Olson, James; Daryani, Vinay M.; Stewart, Clinton F.; Wetmore, Cynthia; Kocak, Mehmet; Onar-Thomas, Arzu; Wagner, Lars; Gururangan, Sridharan; Packer, Roger J.; Blaney, Susan M.; Gajjar, Amar; Kun, Larry E.; Boyett, James M.; Gilbertson, Richard J.
appears sufficient to induce formation of ...
... activation of the transcriptional regulator  p53 
Heterochromatin: A Critical Part of the Genome
Heterochromatin: A Critical Part of the Genome
Wallrath, Lori L.; Vitalini, Michael W.; Elgin, Sarah C. R.
, which leads to increased expression of a ...
... A well-known IDP protein is the tumor suppressor  p53 
Temperature and solvent dependence of the dynamical landscape of tau protein conformations
Temperature and solvent dependence of the dynamical landscape of tau protein conformations
Bianconi, Antonio; Ciasca, Gabriele; Tenenbaum, Alexander; Battisti, Anna; Campi, Gaetano
[22], a hub in the multiple signaling networks ...
... genes involved in regulation of the cell cycle (  p53 
The role of genetic factor in etiopathogenesis of squamous cell carcinoma of the head and neck in young adults
The role of genetic factor in etiopathogenesis of squamous cell carcinoma of the head and neck in young adults
Gawęcki, Wojciech; Kostrzewska-Poczekaj, Magdalena; Gajęcka, Marzena; Milecki, Piotr; Szyfter, Krzysztof; Szyfter, Witold
, p21, Rb, MDM2) [2, 27, 39, 48], but the results ...
... [15–17]. In these malignant neoplasms,  P53 
Genetically Modified Mouse Models of Adamantinomatous Craniopharyngioma
Genetically Modified Mouse Models of Adamantinomatous Craniopharyngioma
Lilian Andoniadou, Cynthia; Martinez-Barbera, Juan Pedro
is over-expressed [18], alluding to the ...
... zum Stellenwert weiterer Biomarker wie, HER2,  p53 
Behandlung des duktalen Carcinoma in situ
Behandlung des duktalen Carcinoma in situ
Thill, M.; Kapsimalakou, S.; Diedrich, K.; Baumann, K.
, VEGF oder MMP2 laufen. ...
... those of the well-known tumor suppressor genes  p53 
Inactivation of the tumor suppressor gene von Hippel-Lindau (VHL) in granulocytes contributes to development of liver hemangiomas in a mouse model
Inactivation of the tumor suppressor gene von Hippel-Lindau (VHL) in granulocytes contributes to development of liver hemangiomas in a mouse model
Bader, Hannah L.; Hsu, Tien
and PTEN, have been documented that contribute to ...
... 2 Gβ1 CPNE1 Copine I 7 Gβ1 TP53I11 Tumor protein  p53 
Tandem Affinity Purification to Identify Cytosolic and Nuclear Gβγ-Interacting Proteins
Tandem Affinity Purification to Identify Cytosolic and Nuclear Gβγ-Interacting Proteins
Campden, Rhiannon; Pétrin, Darlaine; Robitaille, Mélanie; Audet, Nicolas; Gora, Sarah; Angers, Stéphane; Hébert, Terence E.
inducible protein 11 7 Gβ1 MYL6 Myosin, light ...
... kinases/phosphatases, transcription factors like  p53 
Epigenetics and Its Role in Human Cancer
Epigenetics and Its Role in Human Cancer
Raj, Utkarsh; Varadwaj, Pritish Kumar
, Nrf2, NFkB, and peroxiredoxins by redox ...
... the loss of SMAD4, and/or deletions in  p53 
Promoter methylation status of hMLH1, hMSH2, and MGMT genes in colorectal cancer associated with adenoma–carcinoma sequence
Promoter methylation status of hMLH1, hMSH2, and MGMT genes in colorectal cancer associated with adenoma–carcinoma sequence
Lee, Kyung-Hwa; Lee, Ji-Shin; Nam, Jong-Hee; Choi, Chan; Lee, Min-Cheol; Park, Chang-Soo; Juhng, Sang-Woo; Lee, Jae-Hyuk
[3, 4]. ...
... antisense RNAs activated tumor suppressor  p53 
HIV-1 functional cure: will the dream come true?
HIV-1 functional cure: will the dream come true?
Liu, Chao; Ma, Xiancai; Liu, Bingfeng; Chen, Cancan; Zhang, Hui
. ...
... immunoreactivity of keratin, estrogen receptor,  p53 
Quality control in molecular immunohistochemistry
Quality control in molecular immunohistochemistry
True, Lawrence D.
and Ki-67 was lost within 3 months (DiVito et al. ...
... HCC cell growth through reducing Mdm2-mediated  p53 
Down-regulation of sirtuin 3 is associated with poor prognosis in hepatocellular carcinoma after resection
Down-regulation of sirtuin 3 is associated with poor prognosis in hepatocellular carcinoma after resection
Wang, Jia-Xing; Yi, Yong; Li, Yi-Wei; Cai, Xiao-Yan; He, Hong-Wei; Ni, Xiao-Chun; Zhou, Jian; Cheng, Yun-Feng; Jin, Jian-Jun; Fan, Jia; Qiu, Shuang-Jian
degradation [19]. ...
... polymers onto acceptor proteins, including  p53 
Plasma and cerebrospinal fluid pharmacokinetics of ABT-888 after oral administration in non-human primates
Plasma and cerebrospinal fluid pharmacokinetics of ABT-888 after oral administration in non-human primates
Muscal, Jodi A.; Thompson, Patrick A.; Giranda, Vincent L.; Dayton, Brian D.; Bauch, Joy; Horton, Terzah; McGuffey, Leticia; Nuchtern, Jed G.; Dauser, Robert C.; Gibson, Brian W.; Blaney, Susan M.; Su, Jack M.
, histones, and DNA repair proteins [27]. ...
... concentration [12]. DNA fragmentation causes  p53 
Hepatoprotective activity of Sonchus asper against carbon tetrachloride-induced injuries in male rats: a randomized controlled trial
Hepatoprotective activity of Sonchus asper against carbon tetrachloride-induced injuries in male rats: a randomized controlled trial
Khan, Rahmat A; Khan, Muhammad R; Sahreen, Sumaira; Shah, Naseer Ali
gene expression, blocks the cell cycle, and gives ...
... independent, and is associated with mutations in  p53 
Endometrial regeneration and endometrial stem/progenitor cells
Endometrial regeneration and endometrial stem/progenitor cells
Gargett, Caroline E.; Nguyen, Hong P. T.; Ye, Louie
and HER-2/neu [120]. ...
... inflammation, and suppressing colitis through  p53 
Panax Quinquefolius (American Ginseng) and Panax Notoginseng (Notoginseng) in Cancer Chemoprevention
Panax Quinquefolius (American Ginseng) and Panax Notoginseng (Notoginseng) in Cancer Chemoprevention
Wang, Chong-Zhi; Yuan, Chun-Su
-mediated apoptosis of inflammatory cells ...
... (Ref-1), activator protein-1 (AP-1), NF-κB,  p53 
Low level laser therapy/photobiomodulation in the management of side effects of chemoradiation therapy in head and neck cancer: part 1: mechanisms of action, dosimetric, and safety considerations
Low level laser therapy/photobiomodulation in the management of side effects of chemoradiation therapy in head and neck cancer: part 1: mechanisms of action, dosimetric, and safety considerations
Zecha, Judith A. E. M.; Raber-Durlacher, Judith E.; Nair, Raj G.; Epstein, Joel B.; Sonis, Stephen T.; Elad, Sharon; Hamblin, Michael R.; Barasch, Andrei; Migliorati, Cesar A.; Milstein, Dan M. J.; Genot, Marie-Thérèse; Lansaat, Liset; Brink, Ron; Arnabat-Dominguez, Josep; Molen, Lisette; Jacobi, Irene; Diessen, Judi; Lange, Jan; Smeele, Ludi E.; Schubert, Mark M.; Bensadoun, René-Jean
, activating transcription factor/cAMP-response ...
... that overexpressed IL-6 influences the cdk5/  p53 
Inflammatory Cytokines and Alzheimer’s Disease: A Review from the Perspective of Genetic Polymorphisms
Inflammatory Cytokines and Alzheimer’s Disease: A Review from the Perspective of Genetic Polymorphisms
Su, Fan; Bai, Feng; Zhang, Zhijun
pathway to induce the phosphorylation of tau, ...
... low levels of HER2 overexpression, high levels of  p53 
Small Bowel Neoplasms and Polyps
Small Bowel Neoplasms and Polyps
Pourmand, Kamron; Itzkowitz, Steven H.
overexpression, and high frequencies of KRAS ...
... target toxicity may be ameliorated by concomitant  p53 
Animal Models for Retinal Degeneration
Animal Models for Retinal Degeneration
Samardzija, Marijana; Neuhauss, Stephan C. F.; Joly, Sandrine; Kurz-Levin, Malaika; Grimm, Christian
downregulation (90). ...
... of similar efficacy (i.e. autologous HSCT) or  p53 
Blood
Blood
Schmitt, Michael; Freund, Mathias
deletion/mutation (del17p13) requiring ...
... apoptosis in lung cancer cells regardless of  p53 
Genome-Wide Expression Changes in Saccharomyces cerevisiae in Response to High-LET Ionizing Radiation
Genome-Wide Expression Changes in Saccharomyces cerevisiae in Response to High-LET Ionizing Radiation
Mizukami-Murata, Satomi; Iwahashi, Hitoshi; Kimura, Shinzou; Nojima, Kumie; Sakurai, Yoshinori; Saitou, Takeshi; Fujii, Noriko; Murata, Yoshinori; Suga, Shinzi; Kitagawa, Kazuhide; Tanaka, Kenichi; Endo, Satoru; Hoshi, Masaharu
status [12]. ...
... ATM serine/threonine kinase; TP53- tumor protein  p53 
Genetic polymorphisms and gene-dosage effect in ovarian cancer risk and response to paclitaxel/cisplatin chemotherapy
Genetic polymorphisms and gene-dosage effect in ovarian cancer risk and response to paclitaxel/cisplatin chemotherapy
Tecza, Karolina; Pamula-Pilat, Jolanta; Kolosza, Zofia; Radlak, Natalia; Grzybowska, Ewa
). ...
... rate results in nucleolar stress activation of  p53 
The Role of Matrix Metalloproteinase-2 and Metalloproteinase-9 in Embryonic Neural Crest Cells and Their Derivatives
The Role of Matrix Metalloproteinase-2 and Metalloproteinase-9 in Embryonic Neural Crest Cells and Their Derivatives
Kalev-Altman, Rotem; Monsonego-Ornan, Efrat; Sela-Donenfeld, Dalit
which in turn transcriptionally activates ...

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