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... thereby enhancing the pro-apoptotic activity of  p53 
Stem Cell Signaling Pathways in Colorectal Cancer
Stem Cell Signaling Pathways in Colorectal Cancer
Ramakrishna, B. S.; Kumar, Sam Vijay
[48]. ...
... [20] 2 0 NS NS NS TA and IESRCC One of the cases  p53 
HNPCC-associated synchronous early-stage signet-ring cell carcinomas of colonic origin. A comparative morphological and immunohistochemical study of an intramucosal and a submucosal example
HNPCC-associated synchronous early-stage signet-ring cell carcinomas of colonic origin. A comparative morphological and immunohistochemical study of an intramucosal and a submucosal example
Klarskov, Louise; Bernstein, Inge; Holck, Susanne
+ Shimaoka et al. ...
... of transcription 3 TP53INP1 Tumor protein  p53 
microRNA-155 and microRNA-196b in Hepatitis C Virus Infection
microRNA-155 and microRNA-196b in Hepatitis C Virus Infection
Kałużna, Ewelina
inducible nuclear protein 1 aAcquired from the ...
... readily form amorphous aggregates. For example,  p53 
Identifying Solubility-Promoting Buffers for Intrinsically Disordered Proteins Prior to Purification
Identifying Solubility-Promoting Buffers for Intrinsically Disordered Proteins Prior to Purification
Churion, Kelly A.; Bondos, Sarah E.
, a protein that participates in many protein ...
... insulin-like-growth factors) and oncogenes (  p53 
Clinical biomarkers for hypoxia targeting
Clinical biomarkers for hypoxia targeting
Le, Quynh-Thu; Courter, Don
, Vsrc, PTEN, etc) [70–73]. ...
... and 17, epidermal growth factor receptor (EGFR),  p53 
Endogenous NIS Expression in Triple-Negative Breast Cancers
Endogenous NIS Expression in Triple-Negative Breast Cancers
Renier, Corinne; Yao, Chen; Goris, Michael; Ghosh, Malavika; Katznelson, Laurence; Nowles, Kent; Gambhir, Sanjiv S.; Wapnir, Irene
and P-cadherin.4,9–13 To date, however, these ...
... Other molecules, such as EGF receptors (ERBs),  p53 
Interplay of Tumor Microenvironment Cell Types with Parenchymal Cells in Pancreatic Cancer Development and Therapeutic Implications
Interplay of Tumor Microenvironment Cell Types with Parenchymal Cells in Pancreatic Cancer Development and Therapeutic Implications
Guturu, Praveen; Shah, Vijay; Urrutia, Raul
, Smad4/DPC4, are disrupted and may critically ...
... in primary (EGFR/PTEN) or secondary GBM (PDGFR/  p53 
Section on Tumors Biennial Meeting April 13–14, 2007 Washington, DC
Section on Tumors Biennial Meeting April 13–14, 2007 Washington, DC
), no systematic genome-wide comparison of DNA ...
... pathways, e.g., calpain-caspase, nucleophosmin,  p53 
Conjecturable Role of Aluminum in Pathophysiology of Stroke
Conjecturable Role of Aluminum in Pathophysiology of Stroke
Nayak, Prasunpriya
, ROS, Bax, which can lead to mitochondrial ...
... about 50% of colorectal cancers globally [6] as  p53 
Whole genome sequencing reveals potential targets for therapy in patients with refractory KRASmutated metastatic colorectal cancer
Whole genome sequencing reveals potential targets for therapy in patients with refractory KRASmutated metastatic colorectal cancer
Shanmugam, Vijayalakshmi; Ramanathan, Ramesh K; Lavender, Nicole A; Sinari, Shripad; Chadha, Manpreet; Liang, Winnie S; Kurdoglu, Ahmet; Izatt, Tyler; Christoforides, Alexis; Benson, Hollie; Phillips, Lori; Baker, Angela; Murray, Christopher; Hostetter, Galen; Von Hoff, Daniel D; Craig, David W; Carpten, John D
plays key roles in cell regulation, apoptosis, ...
... apoptosis appears to be independent of  p53 
Betulinic acid induces cytochrome c release and apoptosis in a Bax/Bak-independent, permeability transition pore dependent fashion
Betulinic acid induces cytochrome c release and apoptosis in a Bax/Bak-independent, permeability transition pore dependent fashion
Mullauer, Franziska B.; Kessler, Jan H.; Medema, Jan Paul
[6–8], but does show remarkable selectivity for ...
... growth factor“)-Antikörper. ◯ Eine Mutation im  p53 
Aktuelle Behandlungsstrategien für das fortgeschrittene Ovarialkarzinom
Aktuelle Behandlungsstrategien für das fortgeschrittene Ovarialkarzinom
Seck, Katharina; Schmalfeldt, Barbara
-Gen ist Vorrausetzung für eine Therapie mit ...
... [42–44]. Ang also co-immunoprecipitates with  p53 
Novel angiogenin mutants with increased cytotoxicity enhance the depletion of pro-inflammatory macrophages and leukemia cells ex vivo
Novel angiogenin mutants with increased cytotoxicity enhance the depletion of pro-inflammatory macrophages and leukemia cells ex vivo
Cremer, Christian; Braun, Hanna; Mladenov, Radoslav; Schenke, Lea; Cong, Xiaojing; Jost, Edgar; Brümmendorf, Tim H.; Fischer, Rainer; Carloni, Paolo; Barth, Stefan; Nachreiner, Thomas
and Mdm2 and may affect their regulatory ...
... prognostischer Relevanz ist die Expression von  p53 
Endokrin aktive Tumoren des Ovars
Endokrin aktive Tumoren des Ovars
Stegner, H.-E.; Löning, Th.
[12]. ...
... of genes known to affect apoptosis (e.g., Bcl-2,  p53 
Nitric Oxide: A Rate-Limiting Factor for Metastases Development
Nitric Oxide: A Rate-Limiting Factor for Metastases Development
Ortega, Angel; Mena, Salvador; Estrela, José M.
, fas, NO synthetases) may affect tumor growth ...
... al. (2004) Measurement of in vitro AFB1-induced  p53 
Model Fungal Systems for Investigating Food Plant Mycotoxins
Model Fungal Systems for Investigating Food Plant Mycotoxins
Kim, Jong H.; Chan, Kathleen L.
mutations TP53 (Human tumor suppressor gene) ...
... was dependent on the tumor suppressing protein  p53 
Wnt Signaling: Role in Alzheimer Disease and Schizophrenia
Wnt Signaling: Role in Alzheimer Disease and Schizophrenia
Inestrosa, Nibaldo C.; Montecinos-Oliva, Carla; Fuenzalida, Marco
. ...
... pathogenesis-related protein 1) is a novel  p53 
Promoter- and cell-specific epigenetic regulation of CD44, Cyclin D2, GLIPR1 and PTEN by Methyl-CpG binding proteins and histone modifications
Promoter- and cell-specific epigenetic regulation of CD44, Cyclin D2, GLIPR1 and PTEN by Methyl-CpG binding proteins and histone modifications
Müller, Imke; Wischnewski, Frank; Pantel, Klaus; Schwarzenbach, Heidi
-target gene [21] cloned from human glioblastoma ...
... [42] or prevention of activation of the ATR/CHK1/  p53 
Prolyl-hydroxylase inhibition induces SDF-1 associated with increased CXCR4+/CD11b+ subpopulations and cardiac repair
Prolyl-hydroxylase inhibition induces SDF-1 associated with increased CXCR4+/CD11b+ subpopulations and cardiac repair
Ghadge, Santhosh Kumar; Messner, Moritz; Van Pham, Thi; Doppelhammer, Maximilian; Petry, Andreas; Görlach, Agnes; Husse, Britta; Franz, Wolfgang-Michael; Zaruba, Marc-Michael
pathway to decrease apoptosis might also play a ...
... signaling (Kisfalvi et al. 2009) and to induce  p53 
Contextual inhibition of fatty acid synthesis by metformin involves glucose-derived acetyl-CoA and cholesterol in pancreatic tumor cells
Contextual inhibition of fatty acid synthesis by metformin involves glucose-derived acetyl-CoA and cholesterol in pancreatic tumor cells
Cantoria, Mary Jo; Boros, László G.; Meuillet, Emmanuelle J.
-dependent cell cycle arrest and apoptosis (Ben ...
... mutation of other genes, such as K-Ras and  p53 
Colon cancer stem cells
Colon cancer stem cells
Ricci-Vitiani, Lucia; Fabrizi, Eros; Palio, Elisabetta; Maria, Ruggero
, in the context of a growing genomic ...
... cyclin D1, and MDM2, thus indirectly inhibiting  p53 
EGFR (ErbB) Signaling Pathways in Pancreatic Cancer Pathogenesis
EGFR (ErbB) Signaling Pathways in Pancreatic Cancer Pathogenesis
Williams, Monique; Lomberk, Gwen; Urrutia, Raul
AKT is negatively regulated by the tumor ...
... Receptor Type, E 1.548 TP53INP1 Tumor Protein  P53 
Human hematopoietic signal peptide-containing secreted 1 (hHSS1) modulates genes and pathways in glioma: implications for the regulation of tumorigenicity and angiogenesis
Human hematopoietic signal peptide-containing secreted 1 (hHSS1) modulates genes and pathways in glioma: implications for the regulation of tumorigenicity and angiogenesis
Junes-Gill, Katiana S; Lawrence, Chris E; Wheeler, Christopher J; Cordner, Ryan; Gill, Tristan G; Mar, Vernon; Shiri, Liron; Basile, Lena A
Inducible Nuclear Protein 1 1.543 DUSP10 Dual ...
... outcome associations including genes like ApoE,  p53 
ABCC8 Single Nucleotide Polymorphisms are Associated with Cerebral Edema in Severe TBI
ABCC8 Single Nucleotide Polymorphisms are Associated with Cerebral Edema in Severe TBI
Jha, Ruchira M.; Puccio, Ava M.; Okonkwo, David O.; Zusman, Benjamin E.; Park, Seo-Young; Wallisch, Jessica; Empey, Philip E.; Shutter, Lori A.; Clark, Robert S. B.; Kochanek, Patrick M.; Conley, Yvette P.
, and various ILs [2]. ...
... of miR-34c that is linked to the tumor suppressor  p53 
MicroRNA Functions in Osteogenesis and Dysfunctions in Osteoporosis
MicroRNA Functions in Osteogenesis and Dysfunctions in Osteoporosis
Wijnen, Andre J.; Peppel, Jeroen; Leeuwen, Johannes P.; Lian, Jane B.; Stein, Gary S.; Westendorf, Jennifer J.; Oursler, Merry-Jo; Im, Hee-Jeong; Taipaleenmäki, Hanna; Hesse, Eric; Riester, Scott; Kakar, Sanjeev
[50] and prior mouse studies showing a role for ...

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