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... was also associated with a higher incidence of  p53 
Stress, Oxidative Injury and Disease
Stress, Oxidative Injury and Disease
Srivastava, Kaushal K.; Kumar, Ratan
mutations [32]. ...
... For example, an adenovirus vector containing the  p53 
Intratumoral injection of inactivated Sendai virus particles elicits strong antitumor activity by enhancing local CXCL10 expression and systemic NK cell activation
Intratumoral injection of inactivated Sendai virus particles elicits strong antitumor activity by enhancing local CXCL10 expression and systemic NK cell activation
Fujihara, Atsuko; Kurooka, Masayuki; Miki, Tsuneharu; Kaneda, Yasufumi
gene has been clinically tested against various ...
... mechanisms of VCP in them: VCP directly regulated  p53 
VCP gene variation predicts outcome of advanced non-small-cell lung cancer platinum-based chemotherapy
VCP gene variation predicts outcome of advanced non-small-cell lung cancer platinum-based chemotherapy
Peng, J.; Yang, L. X.; Zhao, X. Y.; Gao, Z. Q.; Yang, J.; Wu, W. T.; Wang, H. J.; Wang, J. C.; Qian, J.; Chen, H. Y.; Jin, L.; Bai, C. X.; Han, B. H.; Wang, W. M.; Lu, D. R.
and NF-κB protein levels, by proteasomal ...
... hit Accession Characteristics Ref DEK BC055451  p53 
Serum from mice immunized in the context of Treg inhibition identifies DEK as a neuroblastoma tumor antigen
Serum from mice immunized in the context of Treg inhibition identifies DEK as a neuroblastoma tumor antigen
Zheng, Jin; Kohler, M Eric; Chen, Qingrong; Weber, James; Khan, Javed; Johnson, Bryon D; Orentas, Rimas J
interaction, blocks apoptosis DNA ...
... C-myc and β-catenin cooperate with the loss of  p53 
Wnt activation affects proliferation, invasiveness and radiosensitivity in medulloblastoma
Wnt activation affects proliferation, invasiveness and radiosensitivity in medulloblastoma
Salaroli, Roberta; Ronchi, Alice; Buttarelli, Francesca Romana; Cortesi, Filippo; Marchese, Valeria; Della Bella, Elena; Renna, Cristiano; Baldi, Caterina; Giangaspero, Felice; Cenacchi, Giovanna
to generate multiple members of the primitive ...
... of genes or function of the proteins such as  p53 
Susceptibility to oral cancers with CD95 and CD95L promoter SNPs may vary with the site and gender
Susceptibility to oral cancers with CD95 and CD95L promoter SNPs may vary with the site and gender
Daripally, Sarika; Nallapalle, Sateesh Reddy; Katta, Saritha; Prasad, Vidudala V. T. S.
, c-MYC, and survivin that play important role in ...
... Upon DNA damage, p21 is actively expressed in a  p53 
Regulation of the DNA replication fork: a way to fight genomic instability
Regulation of the DNA replication fork: a way to fight genomic instability
Toueille, Magali; Hübscher, Ulrich
dependent or independent pathway, leading to a ...
... of diverse transcription factors, such as  p53 
Intracellular signaling pathways involved in the release of IL-4 and VEGF from human keratinocytes by activation of kinin B1 receptor: functional relevance to angiogenesis
Intracellular signaling pathways involved in the release of IL-4 and VEGF from human keratinocytes by activation of kinin B1 receptor: functional relevance to angiogenesis
Mejia, Astrid J.; Matus, Carola E.; Pavicic, Francisca; Concha, Miguel; Ehrenfeld, Pamela; Figueroa, Carlos D.
, STAT3, c-Myc, and JunB [11]. ...
... a common mechanism with tumorigenesis, such as  p53 
Identification of functional modules that correlate with phenotypic difference: the influence of network topology
Identification of functional modules that correlate with phenotypic difference: the influence of network topology
Hung, Jui-Hung; Whitfield, Troy W; Yang, Tun-Hsiang; Hu, Zhenjun; Weng, Zhiping; DeLisi, Charles
-dependent apoptosis [24, 25]. ...
... synthase, metallothionein-III, heme oxygenase-1,  p53 
Targeting Nanoparticles to Brain: Impact of N-Methyl d-Aspartate Receptors
Targeting Nanoparticles to Brain: Impact of N-Methyl d-Aspartate Receptors
Engin, Ayse Basak
, and caspase-3, and levels of nitrite and ...
... cystadenomas [12, 17, 19–21]. Mutations in the  p53 
Mucinous Carcinoma of the Ovary
Mucinous Carcinoma of the Ovary
Brown, Jubilee; Frumovitz, Michael
tumor suppressor gene occur less frequently than ...
... HCC, including inactivation of tumor suppressor  p53 
Overexpressed HDGF as an independent prognostic factor is involved in poor prognosis in Chinese patients with liver cancer
Overexpressed HDGF as an independent prognostic factor is involved in poor prognosis in Chinese patients with liver cancer
Zhou, Yanyan; Zhou, Nanxiang; Fang, Weiyi; Huo, Jirong
and epigenetic targeting of cancer-related genes ...
... that were observed in HCC: (a) mutations in  p53 
Macrolide antibiotics differentially influence human HepG2 cytotoxicity and modulate intrinsic/extrinsic apoptotic pathways in rat hepatocellular carcinoma model
Macrolide antibiotics differentially influence human HepG2 cytotoxicity and modulate intrinsic/extrinsic apoptotic pathways in rat hepatocellular carcinoma model
Abdel-Hamid, Nagwa I.; El-Azab, Mona F.; Moustafa, Yasser M.
tumor suppressor gene (Hussain et al. 2007) (b) ...
... in the vast majority of FL with a t(14;18), and  p53 
Idiotype Gene Rescue in Follicular Lymphoma
Idiotype Gene Rescue in Follicular Lymphoma
McCann, Katy; Sahota, Surinder S.; Stevenson, Freda K.; H., Christian
mutations commonly are observed. ...
... stresses induce MIC-1/GDF15 expression via either  p53 
Increased serum levels of GDF-15 associated with mortality and subclinical atherosclerosis in patients on maintenance hemodialysis
Increased serum levels of GDF-15 associated with mortality and subclinical atherosclerosis in patients on maintenance hemodialysis
Yilmaz, H.; Çelik, H.T.; Gurel, O.M.; Bilgic, M.A.; Namuslu, M.; Bozkurt, H.; Ayyildiz, A.; Inan, O.; Bavbek, N.; Akcay, A.
or egr-1 [36]. ...
... target MYC mRNA in lymphoma and interfere with  p53 
MicroRNA-34a inhibits human trophoblast cell invasion by targeting MYC
MicroRNA-34a inhibits human trophoblast cell invasion by targeting MYC
Sun, Manni; Chen, Haiying; Liu, Jing; Tong, Chunxiao; Meng, Tao
-dependent apoptotic pathway [24]. ...
... et al. 1988). The majority of CGs express  p53 
Adenocarcinoma of the Gallbladder (Classical Gallbladder Cancer)
Adenocarcinoma of the Gallbladder (Classical Gallbladder Cancer)
Zimmermann, Arthur
protein in the nuclei (The et al. 1994; Doval et ...
... status as their tumors were smaller, lacked  p53 
Promoter methylation of BRCA1 in the prognosis of breast cancer: a meta-analysis
Promoter methylation of BRCA1 in the prognosis of breast cancer: a meta-analysis
Wu, Liang; Wang, Fengliang; Xu, Ruobing; Zhang, Simin; Peng, Xianzhen; Feng, Yan; Wang, Jianming; Lu, Cheng
mutations, and were of lobular type [37]. ...
... instability and overexpression of the  p53 
Cronkhite–Canada Syndrome
Cronkhite–Canada Syndrome
Cotter, Thomas G.; Al Bawardy, Badr F.; Sweetser, Seth
protein [72]. ...
... (review: Bustaffa et al. 2014) and suppression of  P53 
High exposure to inorganic arsenic by food: the need for risk reduction
High exposure to inorganic arsenic by food: the need for risk reduction
Gundert-Remy, Ursula; Damm, Georg; Foth, Heidi; Freyberger, Alexius; Gebel, Thomas; Golka, Klaus; Röhl, Claudia; Schupp, Thomas; Wollin, Klaus-Michael; Hengstler, Jan Georg
. ...
... line (established from the thoracic aorta of a  p53 
Cytocompatibility of magnesium and AZ31 alloy with three types of cell lines using a direct in vitro method
Cytocompatibility of magnesium and AZ31 alloy with three types of cell lines using a direct in vitro method
Mochizuki, Akira; Yahata, Chie; Takai, Hung
-knockout mouse) was obtained from the Japanese ...
... [115]. From a clinical perspective, the loss of  P53 
Synthetic Genetic Approaches in Colorectal Cancer: Exploiting and Targeting Genome Instability
Synthetic Genetic Approaches in Colorectal Cancer: Exploiting and Targeting Genome Instability
Sajesh, Babu V.; Cisyk, Amy L.; McManus, Kirk J.
function is associated with poor prognosis and ...
... acetylation of nuclear proteins, including  p53 
S-Nitrosylation Regulates Cell Survival and Death in the Central Nervous System
S-Nitrosylation Regulates Cell Survival and Death in the Central Nervous System
Koriyama, Yoshiki; Furukawa, Ayako
, which regulates cell death [51]. ...
... NE carcinomas of the lung [11]. The original Rb/  p53 
Ectopic expression of a small cell lung cancer transcription factor, INSM1 impairs alveologenesis in lung development
Ectopic expression of a small cell lung cancer transcription factor, INSM1 impairs alveologenesis in lung development
Chen, Chiachen; Breslin, Mary B.; Lan, Michael S.
double knockout [12] or triple knockout (double ...
... to the “Acute Phase Response Signaling” and “  p53 
Transcription networks responsible for early regulation of Salmonella-induced inflammation in the jejunum of pigs
Transcription networks responsible for early regulation of Salmonella-induced inflammation in the jejunum of pigs
Hulst, Marcel; Smits, Mari; Vastenhouw, Stéphanie; de Wit, Agnes; Niewold, Theo; van der Meulen, Jan
signaling” pathway. ...

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