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... the regulation of tumor-suppressor genes such as  p53 
DNA and RNA Electronic Properties for Molecular Modifications and Environmental State Diagnostics
DNA and RNA Electronic Properties for Molecular Modifications and Environmental State Diagnostics
Kratochvílová, Irena
can be controlled by charge transfer. ...
... cells are more resistant to 6-OHDA because of  P53 
Agmatine Protects Against 6-OHDA-Induced Apoptosis, and ERK and Akt/GSK Disruption in SH-SY5Y Cells
Agmatine Protects Against 6-OHDA-Induced Apoptosis, and ERK and Akt/GSK Disruption in SH-SY5Y Cells
Amiri, Esmat; Ghasemi, Rasoul; Moosavi, Maryam
decrement and Bcl2 increment, which both result ...
... with transcriptional inactivation of the  p53 
Ultraviolet-B induces ERCC6 repression in lens epithelium cells of age-related nuclear cataract through coordinated DNA hypermethylation and histone deacetylation
Ultraviolet-B induces ERCC6 repression in lens epithelium cells of age-related nuclear cataract through coordinated DNA hypermethylation and histone deacetylation
Wang, Yong; Li, Fei; Zhang, Guowei; Kang, Lihua; Guan, Huaijin
gene [44]. ...
... control (Joska et al. 2014). This is the case of  p53 
The Epigenetically Modulated Circadian System: Implications for Nutrition and Health. Nutritional Modulation of the Circadian Epigenome
The Epigenetically Modulated Circadian System: Implications for Nutrition and Health. Nutritional Modulation of the Circadian Epigenome
Daimiel, Lidia
, which is under circadian control and directly ...
... (REMARK), identified p16INK4, surviving, and  p53 
Melanoma: Diagnosis, Staging, and Treatment. Consensus group recommendations
Melanoma: Diagnosis, Staging, and Treatment. Consensus group recommendations
Berrocal, Alfonso; Cabañas, Luis; Espinosa, Enrique; Fernández-de-Misa, Ricardo; Martín-Algarra, Salvador; Martínez-Cedres, José Carlos; Ríos-Buceta, Luis; Rodríguez-Peralto, José Luis
as the most useful markers to determine outcome ...
... factors, including nuclear factor-κB,  p53 
Thioredoxin 1 as a serum marker for breast cancer and its use in combination with CEA or CA15-3 for improving the sensitivity of breast cancer diagnoses
Thioredoxin 1 as a serum marker for breast cancer and its use in combination with CEA or CA15-3 for improving the sensitivity of breast cancer diagnoses
Park, Byung-Joon; Cha, Mee-Kyung; Kim, Il-Han
, and glucocorticoid and estrogen receptors ...
... transcriptional regulation is affected by NFκB,  p53 
Metastasis Suppressors and the Tumor Microenvironment
Metastasis Suppressors and the Tumor Microenvironment
Bodenstine, Thomas M.; Welch, Danny R.
, β-catenin and other transcriptional factors ...
... that a number of tumor suppressors (e.g.,  p53 
The Expression and Prognosis of FOXO3a and Skp2 in Human Hepatocellular Carcinoma
The Expression and Prognosis of FOXO3a and Skp2 in Human Hepatocellular Carcinoma
Lu, Mudan; Ma, Jianbo; Xue, Wenqun; Cheng, Chun; Wang, You; Zhao, Yueming; Ke, Qing; Liu, Haiou; Liu, Yonghua; Li, Peng; Cui, Xiaopeng; He, Song; Shen, Aiguo
, RB, and p27KIP1) can be degraded by the ...
... [46]. Xiao et al.[47] reported that mutated  p53 
Meta-analysis: preoperative transcatheter arterial chemoembolization does not improve prognosis of patients with resectable hepatocellular carcinoma
Meta-analysis: preoperative transcatheter arterial chemoembolization does not improve prognosis of patients with resectable hepatocellular carcinoma
Zhou, Yanming; Zhang, Xiaofeng; Wu, Lupeng; Ye, Feng; Su, Xu; Shi, Lehua; Li, Bin
could enhance the proliferation of HCC cells and ...
... proteins to the DRPLA product and found IRS  p53 
Polyglutamine Diseases
Polyglutamine Diseases
Okazawa, H.
and DVL1 as candidate binding partners ...
... is well known to cause the alteration in the  p53 
Radiation-resistant extremophiles and their potential in biotechnology and therapeutics
Radiation-resistant extremophiles and their potential in biotechnology and therapeutics
Gabani, Prashant; Singh, Om V.
gene, disrupting the normal cell cycle and ...
... such as knocking down the autophagy inhibitor  p53 
Targeting tissue-specific metabolic signaling pathways in aging: the promise and limitations
Targeting tissue-specific metabolic signaling pathways in aging: the promise and limitations
Hu, Fang; Liu, Feng
, all have been shown to improve animal survival ...
... consequent inhibition and down-regulation of the  p53 
Functional Polymorphisms Associated with Disease-Free Survival in Resected Carcinoma of the Esophagus
Functional Polymorphisms Associated with Disease-Free Survival in Resected Carcinoma of the Esophagus
Boonstra, Jurjen J.; Marion, Ronald; Tilanus, Hugo W.; Dinjens, Winand N. M.
pathway. ...
... downstream of the IGF-1 receptor and modulates a  p53 
Longevity in mice: is stress resistance a common factor?
Longevity in mice: is stress resistance a common factor?
Brown-Borg, H. M.
-dependent oxidative stress response pathway that ...
... abwärts lokalisierte Signalmoleküle wie C-RAF,  p53 
KRAS und weitere Signalmoleküle für die Therapieentscheidung beim metastasierten Kolonkarzinom
KRAS und weitere Signalmoleküle für die Therapieentscheidung beim metastasierten Kolonkarzinom
Ettrich, T.J.
oder Mediatoren der Angiogenese wie TSP-2 sind ...
... upregulated by wild-type tumor suppressor protein  P53 
Association between p21 Ser31Arg polymorphism and the development of cervical lesion in women infected with high risk HPV
Association between p21 Ser31Arg polymorphism and the development of cervical lesion in women infected with high risk HPV
Lima, Géssica; Santos, Erinaldo; Angelo, Hildson; Oliveira, Micheline; Heráclio, Sandra; Leite, Fernanda; Melo, Celso; Crovella, Sergio; Maia, Maria; Souza, Paulo
, inhibits cyclin-CDK2 or cyclin-CDK4 complexes ...
... E2Fs can mediate both cell proliferation and  p53 
Mechanisms of Cardiomyocyte Proliferation and Differentiation in Development and Regeneration
Mechanisms of Cardiomyocyte Proliferation and Differentiation in Development and Regeneration
Yester, Jessie Wettig; Kühn, Bernhard
-dependent/independent apoptosis. ...
... to sTRAILwt or sTRAILDR4, because the drug caused  p53 
TRAIL-receptor preferences in pancreatic cancer cells revisited: Both TRAIL-R1 and TRAIL-R2 have a licence to kill
TRAIL-receptor preferences in pancreatic cancer cells revisited: Both TRAIL-R1 and TRAIL-R2 have a licence to kill
Mohr, Andrea; Yu, Rui; Zwacka, Ralf M.
-independent upregulation of TRAIL-R2 [31]. ...
... as well as controls tumor suppressor pathway (  p53 
Curcumin and tumor immune-editing: resurrecting the immune system
Curcumin and tumor immune-editing: resurrecting the immune system
Bose, Sayantan; Panda, Abir Kumar; Mukherjee, Shravanti; Sa, Gaurisankar
, p21) death receptor pathway (DR4, DR5), ...
... genes such as BRCA1 (breast/ ovarian cancer),  p53 
Dideoxyfingerprinting for Mutation Detection
Dideoxyfingerprinting for Mutation Detection
Bossis, Ioannis; Voutetakis, Antonios; Stratakis, Constantine A.
(follicular thyroid carcinoma and primary breast ...
... LSD1 are characterized to be able to demethylate  p53 
Novel Drugs Targeting the Epigenome
Novel Drugs Targeting the Epigenome
Chen, Zhuo; Li, Honglin
or serve as DNMT and E2F transcription factor 1. ...
... the expression of the tumour suppressor gene,  p53 
The Progression of Cardiomyopathy in the Mitochondrial Disease, Friedreich’s Ataxia
The Progression of Cardiomyopathy in the Mitochondrial Disease, Friedreich’s Ataxia
Ting, Samantha; Huang, Michael Li-Hsuan; Sivagurunathan, Sutharshani; Richardson, Des R.
, and it was also found to be dependent on HIFs ...
... deregulation of the RB/p16INK4a/cyclin D1 and  p53 
Identification of metastasis-associated breast cancer genes using a high-resolution whole genome profiling approach
Identification of metastasis-associated breast cancer genes using a high-resolution whole genome profiling approach
Desouki, Mohamed M.; Liao, Shaoxi; Huang, Huayi; Conroy, Jeffrey; Nowak, Norma J.; Shepherd, Lori; Gaile, Daniel P.; Geradts, Joseph
/p21WAF1/p14ARF/HDM2 pathways is very common ...
... of HIF-1β subunit of HIF-1 in response to  p53 
MicroRNAs and Tumor Vasculature Normalization: Impact on Anti-Tumor Immune Response
MicroRNAs and Tumor Vasculature Normalization: Impact on Anti-Tumor Immune Response
Matejuk, Agata; Collet, Guillaume; Nadim, Mahdi; Grillon, Catherine; Kieda, Claudine
(Yamakuchi et al. 2010). miR-199a was found to ...
... HSCs Inhibits HSCs apoptosis (downregulation of  p53 
Pathophysiology of Cirrhosis and Portal Hypertension
Pathophysiology of Cirrhosis and Portal Hypertension
Ismail, Bahaa Eldeen Senousy; Rivas, John M.; Zervos, Xaralambos B.
) [36] PDGF (mostly PDGF-B and PDGF-D) KCs [6] ...

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