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... 17, wat weer resulteert in verlies van het gen  p53 
17 Ziekten van maag, darm en pancreas
17 Ziekten van maag, darm en pancreas
Smout, A.J.P.M.; Siersema, P.D.
, dat codeert voor een eiwit met ...
... USA) at 4°C overnight. Irrelevant antibodies (  p53 
Apoptotic adipose-derived mesenchymal stem cell therapy protects against lung and kidney injury in sepsis syndrome caused by cecal ligation puncture in rats
Apoptotic adipose-derived mesenchymal stem cell therapy protects against lung and kidney injury in sepsis syndrome caused by cecal ligation puncture in rats
Sung, Pei-Hsun; Chang, Chia-Lo; Tsai, Tzu-Hsien; Chang, Li-Teh; Leu, Steve; Chen, Yung-Lung; Yang, Chic-Chao; Chua, Sarah; Yeh, Kuo-Ho; Chai, Han-Tan; Chang, Hsueh-Wen; Chen, Hong-Hwa; Yip, Hon-Kan
(1:500, Abcam, Cambridge, MA, USA) and mouse ...
... arsenite exposure. Quite surprisingly, total  p53 
Sodium arsenite exposure inhibits AKT and Stat3 activation, suppresses self-renewal and induces apoptotic death of embryonic stem cells
Sodium arsenite exposure inhibits AKT and Stat3 activation, suppresses self-renewal and induces apoptotic death of embryonic stem cells
Ivanov, Vladimir N.; Wen, Gengyun; Hei, Tom K.
levels were relatively stable after sodium ...
... arrest and DNA damage inducible proteins) and  p53 
The biology of radioresistance: similarities, differences and interactions with drug resistance
The biology of radioresistance: similarities, differences and interactions with drug resistance
Powell, Simon N.; Abraham, Edward H.
; growth factors such as FGF, PDGF; and other ...
... evidence that disrupting the nucleolus activates  p53 
The Structure of rDNA Chromatin
The Structure of rDNA Chromatin
Shaw, Peter J.; McKeown, Peter C.
DNA damage pathways in human culture cells (Rubbi ...
... c-Kit, PDGFR-alpha, and S6 kinase as well as  p53 
Variant Renal Carcinoma Histologies: Therapeutic Considerations
Variant Renal Carcinoma Histologies: Therapeutic Considerations
Geynisman, Daniel M.; Stadler, Walter M.
mutations and is associated with poor prognosis ...
... interact with actin, nonmuscle tropomyosin, and  p53 
Nonmuscle myosin-2: mix and match
Nonmuscle myosin-2: mix and match
Heissler, Sarah M.; Manstein, Dietmar J.
, suggesting a role for MstI in cell motility and ...
... as well as identical mutations of K-ras and  p53 
HER2 Expression Beyond Breast Cancer: Therapeutic Implications for Gynecologic Malignancies
HER2 Expression Beyond Breast Cancer: Therapeutic Implications for Gynecologic Malignancies
English, Diana P.; Roque, Dana M.; Santin, Alessandro D.
in the two components [63]. ...
... increased expression of senescence markers  p53 
Cardiovascular Disease and Aging
Cardiovascular Disease and Aging
Chiao, Ying Ann; Lakatta, Edward; Ungvari, Zoltan; Dai, Dao-Fu; Rabinovitch, Peter
and p16INK4a, and an increase in apoptosis. ...
... by downregulating the expression of p16, p21, and  p53 
Protective Effects of Ginseng Leaf Extract Using Enzymatic Extraction Against Oxidative Damage of UVA-Irradiated Human Keratinocytes
Protective Effects of Ginseng Leaf Extract Using Enzymatic Extraction Against Oxidative Damage of UVA-Irradiated Human Keratinocytes
Kim, Mi-Ryung; Lee, Hyun-Sun; Choi, Hyeon-Son; Kim, Sun Young; Park, Yooheon; Suh, Hyung Joo
[34]. ...
... inhibits phosphorylation and transactivation of  p53 
Expression pattern of Notch intracellular domain (NICD) and Hes-1 in preneoplastic and neoplastic human oral squamous epithelium: their correlation with c-Myc, clinicopathological factors and prognosis in Oral cancer
Expression pattern of Notch intracellular domain (NICD) and Hes-1 in preneoplastic and neoplastic human oral squamous epithelium: their correlation with c-Myc, clinicopathological factors and prognosis in Oral cancer
Gokulan, Ravindran; Halagowder, Devaraj
[11]. ...
... is closely linked to the loss of tumor suppressor  p53 
Breast Cancer Therapy–Classical Therapy, Drug Targets, and Targeted Therapy
Breast Cancer Therapy–Classical Therapy, Drug Targets, and Targeted Therapy
Yiannakopoulou, Eugenia Ch
and the amplification of oncogene HER2. ...
... genes, while type II tumors frequently have  p53 
Gynecologic Cancer
Gynecologic Cancer
Altintas, Sevilay; Schrijvers, Dirk L. A. L.; Vermorken, Jan B.
mutations and overexpression or amplification of ...
... to be involved in apoptosis are Bax [7], Bid [8],  p53 
Activation of calpain-1 in human carotid artery atherosclerotic lesions
Activation of calpain-1 in human carotid artery atherosclerotic lesions
Gonçalves, Isabel; Nitulescu, Mihaela; Saido, Takaomi C; Dias, Nuno; Pedro, Luis M; e Fernandes, José Fernandes; Ares, Mikko PS; Pörn-Ares, Isabella
[9], and procaspase-3, -7, -8, and -9 [10, 11]. ...
... kinase, human keratin, Myoglobin, p21, p27,  p53 
Abstracts of the 8th international geminivirus symposium and the 6th international ssDNA comparative virology workshop, 7–10th November 2016, New Delhi
Abstracts of the 8th international geminivirus symposium and the 6th international ssDNA comparative virology workshop, 7–10th November 2016, New Delhi
Roy, Anirban
) and 4 maize streak virus protein structures ...
... H3K4Me3, H3K27Ac, and H3K4Me1. H3K4Me3 enhances  p53 
Computational prediction of transcription factor binding sites based on an integrative approach incorporating genomic and epigenomic features
Computational prediction of transcription factor binding sites based on an integrative approach incorporating genomic and epigenomic features
Seok, Ho-Sik; Kim, Jaebum
-dependent activation and promotes transcription ...
... both plasmids. All control interactions (  p53 
Purification of Protein Complexes and Characterization of Protein-Protein Interactions
Purification of Protein Complexes and Characterization of Protein-Protein Interactions
Swatek, Kirby N.; Lee, Chris B.; Thelen, Jay J.
 + Sv40 positive control, bait + Sv40 negative ...
... It induces apoptosis through the induction of  p53 
Integrated Approach to Oncological Supportive Medicine
Integrated Approach to Oncological Supportive Medicine
Pironi, Bruno; Bonucci, Massimo; Roccia, Maria Grazia; Fioranelli, Massimo
phosphorylation and also suppresses AP1 and ...
... of certain tumor suppressor genes and oncogenes (  p53 
Hematopoietic Tumors
Hematopoietic Tumors
Henrich, Manfred
, Rb, N-ras, and p16), and telomerase activity. ...
... of DDR1 activity in cells containing wild-type  p53 
Downregulation of discoidin domain receptor 2 decreases tumor growth of hepatocellular carcinoma
Downregulation of discoidin domain receptor 2 decreases tumor growth of hepatocellular carcinoma
Park, Joong-Won; Lee, Yeon-Su; Kim, Jin Sook; Lee, Sook-Kyung; Kim, Bo Hyun; Lee, Jung Ahn; Lee, Nam Oak; Kim, Seong Hoon; Hong, Eun Kyung
was reported to result in increased apoptosis ...
... breast cancer antigens such as tumor protein  p53 
Early Detection of Breast Cancer
Early Detection of Breast Cancer
Jotwani, Aparna C.; Gralow, Julie R.
(TP53), HER2, and MUC1.[37,38] TP53 is a nuclear ...
... a nuclear protein homolog of the tumor suppressor  p53 
Microscopy image analysis of p63 immunohistochemically stained laryngeal cancer lesions for predicting patient 5-year survival
Microscopy image analysis of p63 immunohistochemically stained laryngeal cancer lesions for predicting patient 5-year survival
Ninos, Konstantinos; Kostopoulos, Spiros; Kalatzis, Ioannis; Sidiropoulos, Konstantinos; Ravazoula, Panagiota; Sakellaropoulos, George; Panayiotakis, George; Economou, George; Cavouras, Dionisis
, involved in embryonic development, and is a ...
... as cytokine GM-CSF, the tumor suppressor gene  p53 
Development of Chimeric Gene Regulators for Cancer-specific Gene Therapy with both Transcriptional and Translational Targeting
Development of Chimeric Gene Regulators for Cancer-specific Gene Therapy with both Transcriptional and Translational Targeting
Fang, Yu Xiang; Zhang, Xiao Bo; Wei, Wei; Liu, Yi Wen; Chen, Jin Zhong; Xue, Jing Lun; Tian, Ling
, and others. ...
... 15 years, immunohistochemical staining for  p53 
What is low-risk prostate cancer and what is its natural history?
What is low-risk prostate cancer and what is its natural history?
O’Donnell, Helen; Parker, Chris
, Ki-67 and Bcl-2 were associated with ...
... pathway: Zeng et al. showed that HDAC3-mediated  p53 
On the epigenetics of vascular regulation and disease
On the epigenetics of vascular regulation and disease
Schleithoff, Christina; Voelter-Mahlknecht, Susanne; Dahmke, Indra Navina; Mahlknecht, Ulrich
deacetylation and p21 activation caused by shear ...

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