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... of wild type BRCA1 expression, and a wild type  p53 
Transactivation of the estrogen receptor promoter by BRCA1
Transactivation of the estrogen receptor promoter by BRCA1
Archey, William B.; Arrick, Bradley A.
status [20, 21]. ...
... enhancer factor 2), NF-κβ, the tumor suppressor  p53 
Neurovascular Mechanisms of Ischemia Tolerance Against Brain Injury
Neurovascular Mechanisms of Ischemia Tolerance Against Brain Injury
Dave, Kunjan R.; Thompson, John W.; Neumann, Jake T.; Perez-Pinzon, Miguel A.; Lin, Hung W.
, members of the FOXO transcription factor ...
... a nonmutated but functionally deficient form of  p53 
The role of cancer-associated fibroblasts, solid stress and other microenvironmental factors in tumor progression and therapy resistance
The role of cancer-associated fibroblasts, solid stress and other microenvironmental factors in tumor progression and therapy resistance
Kharaishvili, Gvantsa; Simkova, Dana; Bouchalova, Katerina; Gachechiladze, Mariam; Narsia, Nato; Bouchal, Jan
and TP53 mutation status may be a predictor of ...
... during the cultivation process and developed a  p53 
SNP microarray analyses reveal copy number alterations and progressive genome reorganization during tumor development in SVT/t driven mice breast cancer
SNP microarray analyses reveal copy number alterations and progressive genome reorganization during tumor development in SVT/t driven mice breast cancer
Standfuß, Christoph; Pospisil, Heike; Klein, Andreas
hotspot mutation (G242). ...
... interacting with some client proteins such as  p53 
Cloning of cytoplasmic heat shock protein 90 (FcHSP90) from Fenneropenaeus chinensis and its expression response to heat shock and hypoxia
Cloning of cytoplasmic heat shock protein 90 (FcHSP90) from Fenneropenaeus chinensis and its expression response to heat shock and hypoxia
Li, Fuhua; Luan, Wei; Zhang, Chengsong; Zhang, Jiquan; Wang, Bing; Xie, Yusu; Li, Shihao; Xiang, Jianhai
(Muller et al. 2004), and the C-terminal domain ...
... and YY2 were previously reported to activate the  p53 
Yin-Yang 1 and Yin-Yang 2 exert opposing effects on the promoter activity of interleukin 4
Yin-Yang 1 and Yin-Yang 2 exert opposing effects on the promoter activity of interleukin 4
Lee, Sung Ho; Cho, Young-Chang; Jeong, Hyung Min; Kim, Kyung Hee; Choi, Hyun Jin; Lee, Kwang Youl; Kang, Bok Yun
promoter (Nguyen et al. 2004; Gronroos et al. ...
... in hypoxia by activating anticancer responses (  p53 
Hypoxic conditions increases H2S-induced ER stress in A2870 cells
Hypoxic conditions increases H2S-induced ER stress in A2870 cells
Lencesova, Lubomira; Vlcek, Miroslav; Krizanova, Olga; Hudecova, Sona
, ARE, IRF1, Pax6, and XRE) and suppressing ...
... stress-induced NF-κB pathway by recruiting ATM,  p53 
Imaging of nuclear factor κB activation induced by ionizing radiation in human embryonic kidney (HEK) cells
Imaging of nuclear factor κB activation induced by ionizing radiation in human embryonic kidney (HEK) cells
Chishti, Arif Ali; Baumstark-Khan, Christa; Hellweg, Christine E.; Reitz, Günther
-inducible death domain-containing protein (PIDD) ...
... 1,2-2,4 mutaties in andere hoog penetrante genen:  p53 
Mammatumoren
Mammatumoren
Velde, C. J. H.; Elkhuizen, P. H. M.; Nortier, J. W. R.; Diest, P. J.; Zonderland, H. M.
, PTEN 1-6 eerstegraadsverwant met mammacarcinoom ...
... family members, and inhibit the degradation of  p53 
Sorafenib enhances proteasome inhibitor-induced cell death via inactivation of Akt and stress-activated protein kinases
Sorafenib enhances proteasome inhibitor-induced cell death via inactivation of Akt and stress-activated protein kinases
Honma, Yuichi; Shimizu, Satoshi; Takehara, Tetsuo; Harada, Masaru
and p27 [10]. ...
... (Niculescu et al. 1998; Jiang et al. 2000). Using  p53 
Endoreplication and polyploidy in primary culture of rat hepatic stellate cells
Endoreplication and polyploidy in primary culture of rat hepatic stellate cells
Dudas, Jozsef; Saile, Bernhard; El-Armouche, Hamudi; Aprigliano, Isabella; Ramadori, Giuliano
- and pRb-negative cell lines, they described G2 ...
... p21 promoter, promoting p21 transcription in a  p53 
CG0006, a novel histone deacetylase inhibitor, induces breast cancer cell death via histone-acetylation and chaperone-disrupting pathways independent of ER status
CG0006, a novel histone deacetylase inhibitor, induces breast cancer cell death via histone-acetylation and chaperone-disrupting pathways independent of ER status
Kim, Hyun Mi; Kim, Choung-Soo; Lee, Je-Hwan; Jang, Se Jin; Hwang, Jung Jin; Ro, Seonggu; Hyun, Young-Lan; Choi, Jene
-independent manner [18, 19]. ...
... proteins, such as BRCA1 and tumor suppressor  P53 
Association of the ATM gene polymorphisms with papillary thyroid cancer
Association of the ATM gene polymorphisms with papillary thyroid cancer
Gu, Yulu; Yu, Yaqin; Ai, Lizhe; Shi, Jieping; Liu, Xiaoli; Sun, Hui; Liu, Yawen
[13, 16, 19]. ...
... to increase the ventricular expression of  p53 
Slow conduction and gap junction remodeling in murine ventricle after chronic alcohol ingestion
Slow conduction and gap junction remodeling in murine ventricle after chronic alcohol ingestion
Lai, Yu-Jun; Hung, Chung-Lieh; Hong, Ray-Ching; Tseng, Ya-Ming; Lin, Cheng-I; Ko, Yu-Shien; Tsai, Cheng-Ho; Yeh, Hung-I
[23], which is known to inhibit angiogenesis ...
... engineered to sequentially disrupt expression of  p53 
Cancer Stem Cells and Glioblastoma Multiforme: Pathophysiological and Clinical Aspects
Cancer Stem Cells and Glioblastoma Multiforme: Pathophysiological and Clinical Aspects
Soeda, Akio; Shaffrey, Mark E.; Park, Deric M.
and NF1, tumor formation was restricted to the ...
... phase accompanied with increased levels of p21,  p53 
Cytokine functions of TIMP-1
Cytokine functions of TIMP-1
Ries, Christian
and p57 [40]. ...
... migration and polarity [2–5], the  p53 
Gene Expression Analysis: Applications
Gene Expression Analysis: Applications
Savas, Peter; Teo, Zhi Ling; Loi, Sherene
signalling pathways involved in genomic ...
... transcription factors, including AP-1, AP-2,  p53 
Mechanisms of matrix metalloproteinase-2 (mmp-2) transcriptional repression by progesterone in jar choriocarcinoma cells
Mechanisms of matrix metalloproteinase-2 (mmp-2) transcriptional repression by progesterone in jar choriocarcinoma cells
Goldman, Shlomit; Lovett, David H; Shalev, Eliezer
, nm-23β, and SP1/3 have been reported [14–19]. ...
... including a fluorogenic acetylated Lys382  p53 
Carboxyamidotriazole alleviates muscle atrophy in tumor-bearing mice by inhibiting NF-κB and activating SIRT1
Carboxyamidotriazole alleviates muscle atrophy in tumor-bearing mice by inhibiting NF-κB and activating SIRT1
Chen, Chen; Ju, Rui; Zhu, Lei; Li, Juan; Chen, Wei; Zhang, De-chang; Ye, Cai-ying; Guo, Lei
peptide (50 μM) and NAD (100 μM) at 37 °C for ...
... are generally lacking, but data suggests that  p53 
The role of PAPP-A in the IGF system: location, location, location
The role of PAPP-A in the IGF system: location, location, location
Oxvig, Claus
can be involved in oncogenic regulation of PAPP-A ...
... found in type II ovarian cancers but BRAC1/2 and  p53 
Ovarian cancer microenvironment: implications for cancer dissemination and chemoresistance acquisition
Ovarian cancer microenvironment: implications for cancer dissemination and chemoresistance acquisition
Thibault, Benoît; Castells, Magali; Delord, Jean-Pierre; Couderc, Bettina
mutations are frequent. ...
... (12/35) by patulin. Among them, the tumor protein  p53 
Patulin transformation products and last intermediates in its biosynthetic pathway, E- and Z-ascladiol, are not toxic to human cells
Patulin transformation products and last intermediates in its biosynthetic pathway, E- and Z-ascladiol, are not toxic to human cells
Tannous, Joanna; Snini, Selma P.; Khoury, Rhoda; Canlet, Cécile; Pinton, Philippe; Lippi, Yannick; Alassane-Kpembi, Imourana; Gauthier, Thierry; Khoury, André; Atoui, Ali; Zhou, Ting; Lteif, Roger; Oswald, Isabelle P.; Puel, Olivier
and the CTNNB1 transcription factor were ...
... BH3 family (Allagnat et al. 2011). In contrast,  p53 
Endoplasmic Reticulum Stress and Obesity
Endoplasmic Reticulum Stress and Obesity
Yilmaz, Erkan
upregulated modulator of apoptosis (PUMA) and ...
... response/cell cycle Prp19 (DDR), Magea2 (inhibits  p53 
Distinct gene-expression profiles characterize mammary tumors developed in transgenic mice expressing constitutively active and C-terminally truncated variants of STAT5
Distinct gene-expression profiles characterize mammary tumors developed in transgenic mice expressing constitutively active and C-terminally truncated variants of STAT5
Eilon, Tali; Barash, Itamar
activation) Apoptosis inhibition Cflar Tight ...
... GFP-tag plasmid. H1299 cells showed the lack of  p53 
PCAF-mediated acetylation of Lin28B increases let-7 biogenesis in lung adenocarcinoma H1299 cells
PCAF-mediated acetylation of Lin28B increases let-7 biogenesis in lung adenocarcinoma H1299 cells
Qu, Ting-ting; Chen, Fei; Wang, Jing; Zhang, Yan-jun; Cheng, Mo-bin; Sun, Wen-zheng; Shen, Yu-fei; Zhang, Ye
protein expression by western blot assay. ...

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