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... Epigenetic biomarkers, such as DNA  methylation 
Epigenetic Biomarkers of Breast Cancer Risk: Across the Breast Cancer Prevention Continuum
Epigenetic Biomarkers of Breast Cancer Risk: Across the Breast Cancer Prevention Continuum
Terry, Mary Beth; McDonald, Jasmine A.; Wu, Hui Chen; Eng, Sybil; Santella, Regina M.
, can increase cancer risk through ...
... for a mechanistic link between DNA  methylation 
Methylation in Colorectal Cancer
Methylation in Colorectal Cancer
Mokarram, Pooneh; Estiar, Mehrdad Asghari; Ashktorab, Hassan
and histone deacetylation has also been ...
... of gene-specific and genomic DNA  methylation 
Blood-Derived DNA Methylation Markers of Cancer Risk
Blood-Derived DNA Methylation Markers of Cancer Risk
Marsit, Carmen; Christensen, Brock
has been extensively characterized in ...
... modifications, particularly DNA  methylation 
DNA methylation markers in colorectal cancer
DNA methylation markers in colorectal cancer
Kim, Myoung Sook; Lee, Juna; Sidransky, David
in selected gene promoters, are ...
... around CpG islands. It is unclear whether  methylation 
Characterization of human gastric carcinoma-related methylation of 9 miR CpG islands and repression of their expressions in vitro and in vivo
Characterization of human gastric carcinoma-related methylation of 9 miR CpG islands and repression of their expressions in vitro and in vivo
Du, Yantao; Liu, Zhaojun; Gu, Liankun; Zhou, Jing; Zhu, Bu-dong; Ji, Jiafu; Deng, Dajun
of these CpG islands represses miR ...
... Background Aberrant DNA  methylation 
DNA methylation analysis reveals distinct methylation signatures in pediatric germ cell tumors
DNA methylation analysis reveals distinct methylation signatures in pediatric germ cell tumors
Amatruda, James F; Ross, Julie A; Christensen, Brock; Fustino, Nicholas J; Chen, Kenneth S; Hooten, Anthony J; Nelson, Heather; Kuriger, Jacquelyn K; Rakheja, Dinesh; Frazier, A Lindsay; Poynter, Jenny N
is a prominent feature of many cancers, ...
... of multi-gene, locus-specific DNA  methylation 
Differential methylation relative to breast cancer subtype and matched normal tissue reveals distinct patterns
Differential methylation relative to breast cancer subtype and matched normal tissue reveals distinct patterns
Bardowell, Sabrina A.; Parker, Joel; Fan, Cheng; Crandell, Jamie; Perou, Charles M.; Swift-Scanlan, Theresa
patterns in relation to molecular subtype ...
... driver of tumorigenesis, and DNA  methylation 
DNA methylation in ductal carcinoma in situof the breast
DNA methylation in ductal carcinoma in situof the breast
Pang, Jia-Min B; Dobrovic, Alexander; Fox, Stephen B
of specific gene promoters provides ...
... global DNA hypomethylation. Aberrant DNA  methylation 
Hypermethylation of CDKN2A exon 2 in tumor, tumor-adjacent and tumor-distant tissues from breast cancer patients
Hypermethylation of CDKN2A exon 2 in tumor, tumor-adjacent and tumor-distant tissues from breast cancer patients
Spitzwieser, Melanie; Entfellner, Elisabeth; Werner, Bettina; Pulverer, Walter; Pfeiler, Georg; Hacker, Stefan; Cichna-Markl, Margit
levels have, however, not only been found ...
... poor patient’s prognosis. Beside promoter  methylation 
Epigenetic modulation of the drug resistance genes MGMT, ABCB1 and ABCG2 in glioblastoma multiforme
Epigenetic modulation of the drug resistance genes MGMT, ABCB1 and ABCG2 in glioblastoma multiforme
Oberstadt, Moritz C; Bien-Möller, Sandra; Weitmann, Kerstin; Herzog, Susann; Hentschel, Katharina; Rimmbach, Christian; Vogelgesang, Silke; Balz, Ellen; Fink, Matthias; Michael, Heike; Zeden, Jan-Philip; Bruckmüller, Henrike; Werk, Anneke N; Cascorbi, Ingolf; Hoffmann, Wolfgang; Rosskopf, Dieter; Schroeder, Henry WS; Kroemer, Heyo K
of the O 6 ...
... to investigate the applicability of the  methylation 
Applicability of HIN-1, MGMT and RASSF1A promoter methylation as biomarkers for detecting field cancerization in breast cancer
Applicability of HIN-1, MGMT and RASSF1A promoter methylation as biomarkers for detecting field cancerization in breast cancer
Spitzwieser, Melanie; Holzweber, Elisabeth; Pfeiler, Georg; Hacker, Stefan; Cichna-Markl, Margit
status of six tumor suppressor genes as ...
... a pattern of modification of DNA by DNA  methylation 
DNA Methylation in Breast Cancer
DNA Methylation in Breast Cancer
Szyf, Moshe
and a profile of expression of noncoding ...
... evidence on the prognostic utility of DNA  methylation 
Methylation markers for prostate cancer prognosis: a systematic review
Methylation markers for prostate cancer prognosis: a systematic review
Chao, Chun; Chi, Margaret; Preciado, Melissa; Black, Mary Helen
markers in prostate cancer and ascertain ...
... potential for the development of new DNA  methylation 
A panel of genes methylated with high frequency in colorectal cancer
A panel of genes methylated with high frequency in colorectal cancer
Mitchell, Susan M; Ross, Jason P; Drew, Horace R; Ho, Thu; Brown, Glenn S; Saunders, Neil FW; Duesing, Konsta R; Buckley, Michael J; Dunne, Rob; Beetson, Iain; Rand, Keith N; McEvoy, Aidan; Thomas, Melissa L; Baker, Rohan T; Wattchow, David A; Young, Graeme P; Lockett, Trevor J; Pedersen, Susanne K; LaPointe, Lawrence C; Molloy, Peter L
biomarkers or panels to improve the ...
... array-based analysis of genome-wide DNA  methylation 
Global, cancer-specific microRNA cluster hypomethylation was functionally associated with the development of non-B non-C hepatocellular carcinoma
Global, cancer-specific microRNA cluster hypomethylation was functionally associated with the development of non-B non-C hepatocellular carcinoma
Nojima, Masanori; Matsui, Takeshi; Tamori, Akihiro; Kubo, Shoji; Shirabe, Ken; Kimura, Koichi; Shimada, Mitsuo; Utsunomiya, Tohru; Kondo, Yasuteru; Iio, Etsuko; Naito, Yutaka; Ochiya, Takahiro; Tanaka, Yasuhito
(N = 43 pairs) and mRNA/miRNA expression ...
... DNA  methylation 
Lung cancer: From single-gene methylation to methylome profiling
Lung cancer: From single-gene methylation to methylome profiling
Heller, Gerwin; Zielinski, Christoph C.; Zöchbauer-Müller, Sabine
as part of the epigenetic gene-silencing ...
... DNA methylationEpigenetic therapy DNA  methylation 
Epigenetic Basis of Human Cancer
Epigenetic Basis of Human Cancer
Mikeska, Thomas; Dobrovic, Alexander
, histone modificationsEpigenetic therapy ...
... microarrays to compare genomewide  methylation 
Identification and characterization of locus-specific methylation patterns within novel loci undergoing hypermethylation during breast cancer pathogenesis
Identification and characterization of locus-specific methylation patterns within novel loci undergoing hypermethylation during breast cancer pathogenesis
Wojdacz, Tomasz K; Windeløv, Johanne A; Thestrup, Britta B; Damsgaard, Tine E; Overgaard, Jens; Hansen, Lise Lotte
patterns of breast carcinomas (n = 20) ...
... Background Aberrant DNA  methylation 
An integrated genomics analysis of epigenetic subtypes in human breast tumors links DNA methylation patterns to chromatin states in normal mammary cells
An integrated genomics analysis of epigenetic subtypes in human breast tumors links DNA methylation patterns to chromatin states in normal mammary cells
Holm, Karolina; Staaf, Johan; Lauss, Martin; Aine, Mattias; Lindgren, David; Bendahl, Pär-Ola; Vallon-Christersson, Johan; Barkardottir, Rosa Bjork; Höglund, Mattias; Borg, Åke; Jönsson, Göran; Ringnér, Markus
is frequently observed in breast cancer. ...
... the diagnostic value of BRCA1/2  methylation 
BRCA promoter methylation in sporadic versus BRCA germline mutation-related breast cancers
BRCA promoter methylation in sporadic versus BRCA germline mutation-related breast cancers
Vos, Shoko; Moelans, Cathy Beatrice; van Diest, Paul Joannes
in distinguishing breast carcinomas of ...
... sought to evaluate whether DNA promoter  methylation 
DNA methylation profiling of phyllodes and fibroadenoma tumours of the breast
DNA methylation profiling of phyllodes and fibroadenoma tumours of the breast
Huang, Katie T.; Dobrovic, Alexander; Yan, Max; Karim, Rooshdiya Z.; Lee, C. Soon; Lakhani, Sunil R.; Fox, Stephen B.
profiling using selected genes known to ...
... two decades. In particular, aberrant DNA  methylation 
Mechanisms for the induction of gastric cancer by Helicobacter pylori infection: aberrant DNA methylation pathway
Mechanisms for the induction of gastric cancer by Helicobacter pylori infection: aberrant DNA methylation pathway
Maeda, Masahiro; Moro, Hiroshi; Ushijima, Toshikazu
is induced in multiple driver genes, ...
... infection potently induces aberrant DNA  methylation 
Persistence of a component of DNA methylation in gastric mucosae after Helicobacter pylori eradication
Persistence of a component of DNA methylation in gastric mucosae after Helicobacter pylori eradication
Nakajima, Takeshi; Enomoto, Shotaro; Yamashita, Satoshi; Ando, Takayuki; Nakanishi, Yukihiro; Nakazawa, Kazuyuki; Oda, Ichiro; Gotoda, Takuji; Ushijima, Toshikazu
in gastric mucosae, and its accumulation ...
... as epigenetically silenced by promotor  methylation 
The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma
The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma
Djos, Anna; Martinsson, Tommy; Kogner, Per; Carén, Helena
in human cancers. ...
... hope for improved therapy. Aberrant  methylation 
Frequent but borderline methylation of p16INK4a and TIMP3 in medulloblastoma and sPNET revealed by quantitative analyses
Frequent but borderline methylation of p16INK4a and TIMP3 in medulloblastoma and sPNET revealed by quantitative analyses
Mühlisch, J.; Bajanowski, T.; Rickert, C. H.; Roggendorf, W.; Würthwein, G.; Jürgens, H.; Frühwald, M. C.
is common in malignant brain tumors of ...