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... altering the genetic sequence itself. DNA  methylation 
The DNA Methylome: An Interface Between the Environment, Immunity, and Ageing
The DNA Methylome: An Interface Between the Environment, Immunity, and Ageing
McEwen, Lisa M.; Goodman, Sarah J.; Kobor, Michael S.; Jones, Meaghan J.
is arguably the most well-characterized ...
... rates of T2D and metabolic syndrome, with  methylation 
Tissue-specific methylation profile in obese patients with type 2 diabetes before and after Roux-en-Y gastric bypass
Tissue-specific methylation profile in obese patients with type 2 diabetes before and after Roux-en-Y gastric bypass
Sala, Priscila; Miranda Torrinhas, Raquel Susana Matos; Fonseca, Danielle Cristina; Ravacci, Graziela Rosa; Waitzberg, Dan Linetzky; Giannella-Neto, Daniel
profiles in promoter regions of genes in ...
... of multi-gene, locus-specific DNA  methylation 
Differential methylation relative to breast cancer subtype and matched normal tissue reveals distinct patterns
Differential methylation relative to breast cancer subtype and matched normal tissue reveals distinct patterns
Bardowell, Sabrina A.; Parker, Joel; Fan, Cheng; Crandell, Jamie; Perou, Charles M.; Swift-Scanlan, Theresa
patterns in relation to molecular subtype ...
... Epigenetic events such as DNA-  methylation 
The Role of Epigenetics
The Role of Epigenetics
Kwabi-Addo, Bernard
changes have increasingly been found to ...
... a pattern of modification of DNA by DNA  methylation 
DNA Methylation in Breast Cancer
DNA Methylation in Breast Cancer
Szyf, Moshe
and a profile of expression of noncoding ...
... genome-wide studies found that DNA  methylation 
Whole DNA methylome profiling in lung cancer cells before and after epithelial-to-mesenchymal transition
Whole DNA methylome profiling in lung cancer cells before and after epithelial-to-mesenchymal transition
Liu, Fatao; Zhou, Yi; Zhou, Daizhan; Kan, Mengyuan; Niu, Xiaomin; Zhang, Zhou; Zhang, Di; Tao, Liming; He, Lin; Zhan, Lixing; Liu, Yun
was unchanged during EMT induced by TGF-β ...
... where the epigenetic marks of DNA  methylation 
Placental methylome analysis from a prospective autism study
Placental methylome analysis from a prospective autism study
Schroeder, Diane I.; Schmidt, Rebecca J.; Crary-Dooley, Florence K.; Walker, Cheryl K.; Ozonoff, Sally; Tancredi, Daniel J.; Hertz-Picciotto, Irva; LaSalle, Janine M.
may be useful as risk biomarkers. ...
... DNA methylationEpigenetic therapy DNA  methylation 
Epigenetic Basis of Human Cancer
Epigenetic Basis of Human Cancer
Mikeska, Thomas; Dobrovic, Alexander
, histone modificationsEpigenetic therapy ...
... as mother, father, and teacher reports.  Methylation 
Epigenetic regulation of the DRD4 gene and dimensions of attention-deficit/hyperactivity disorder in children
Epigenetic regulation of the DRD4 gene and dimensions of attention-deficit/hyperactivity disorder in children
Dadds, Mark R.; Schollar-Root, Olivia; Lenroot, Rhoshel; Moul, Caroline; Hawes, David J.
levels were assayed for the island of 18 ...
... sought to evaluate whether DNA promoter  methylation 
DNA methylation profiling of phyllodes and fibroadenoma tumours of the breast
DNA methylation profiling of phyllodes and fibroadenoma tumours of the breast
Huang, Katie T.; Dobrovic, Alexander; Yan, Max; Karim, Rooshdiya Z.; Lee, C. Soon; Lakhani, Sunil R.; Fox, Stephen B.
profiling using selected genes known to ...
... two decades. In particular, aberrant DNA  methylation 
Mechanisms for the induction of gastric cancer by Helicobacter pylori infection: aberrant DNA methylation pathway
Mechanisms for the induction of gastric cancer by Helicobacter pylori infection: aberrant DNA methylation pathway
Maeda, Masahiro; Moro, Hiroshi; Ushijima, Toshikazu
is induced in multiple driver genes, ...
...  Methylation 
Peripheral blood leukocyte distribution and body mass index are associated with the methylation pattern of the androgen receptor promoter
Peripheral blood leukocyte distribution and body mass index are associated with the methylation pattern of the androgen receptor promoter
Movérare-Skrtic, Sofia; Mellström, Dan; Vandenput, Liesbeth; Ehrich, Mathias; Ohlsson, Claes
of CpG sites in the promoter region can ...
... infection potently induces aberrant DNA  methylation 
Persistence of a component of DNA methylation in gastric mucosae after Helicobacter pylori eradication
Persistence of a component of DNA methylation in gastric mucosae after Helicobacter pylori eradication
Nakajima, Takeshi; Enomoto, Shotaro; Yamashita, Satoshi; Ando, Takayuki; Nakanishi, Yukihiro; Nakazawa, Kazuyuki; Oda, Ichiro; Gotoda, Takuji; Ushijima, Toshikazu
in gastric mucosae, and its accumulation ...
... this association are unclear, but DNA  methylation 
Physical Activity and Differential Methylation of Breast Cancer Genes Assayed from Saliva: A Preliminary Investigation
Physical Activity and Differential Methylation of Breast Cancer Genes Assayed from Saliva: A Preliminary Investigation
Bryan, Angela D.; Magnan, Renee E.; Hooper, Ann E. Caldwell; Harlaar, Nicole; Hutchison, Kent E.
has been suggested. ...
... hope for improved therapy. Aberrant  methylation 
Frequent but borderline methylation of p16INK4a and TIMP3 in medulloblastoma and sPNET revealed by quantitative analyses
Frequent but borderline methylation of p16INK4a and TIMP3 in medulloblastoma and sPNET revealed by quantitative analyses
Mühlisch, J.; Bajanowski, T.; Rickert, C. H.; Roggendorf, W.; Würthwein, G.; Jürgens, H.; Frühwald, M. C.
is common in malignant brain tumors of ...
... has been shown to occur in cancer; DNA  methylation 
IGF-II promoter methylation and ovarian cancer prognosis
IGF-II promoter methylation and ovarian cancer prognosis
Beeghly, A. C.; Katsaros, D.; Wiley, A. L.; Rigault de la Longrais, I. A.; Prescott, A. T.; Chen, H.; Puopolo, M.; Rutherford, T. J.; Yu, H.
regulates promoter use. ...
... shared gene expression and a lack of  methylation 
Variable methylation of the imprinted gene, SNRPN, supports a relationship between intracranial germ cell tumours and neural stem cells
Variable methylation of the imprinted gene, SNRPN, supports a relationship between intracranial germ cell tumours and neural stem cells
Lee, Shih-Han; Appleby, Vanessa; Jeyapalan, Jennie N.; Palmer, Roger D.; Nicholson, James C.; Sottile, Virginie; Gao, Erning; Coleman, Nicholas; Scotting, Paul J.
of imprinted genes, including SNRPN. ...
... of various subtypes by genome-wide DNA  methylation 
Genome-wide methylation profiles in primary intracranial germ cell tumors indicate a primordial germ cell origin for germinomas
Genome-wide methylation profiles in primary intracranial germ cell tumors indicate a primordial germ cell origin for germinomas
Fukushima, Shintaro; Yamashita, Satoshi; Kobayashi, Hisato; Takami, Hirokazu; Fukuoka, Kohei; Nakamura, Taishi; Yamasaki, Kai; Matsushita, Yuko; Nakamura, Hiromi; Totoki, Yasushi; Kato, Mamoru; Suzuki, Tomonari; Mishima, Kazuhiko; Yanagisawa, Takaaki; Mukasa, Akitake; Saito, Nobuhito; Kanamori, Masayuki; Kumabe, Toshihiro; Tominaga, Teiji; Nagane, Motoo; Iuchi, Toshihiko; Yoshimoto, Koji; Mizoguchi, Masahiro; Tamura, Kaoru; Sakai, Keiichi; Sugiyama, Kazuhiko; Nakada, Mitsutoshi; Yokogami, Kiyotaka; Takeshima, Hideo; Kanemura, Yonehiro; Matsuda, Masahide; Matsumura, Akira; Kurozumi, Kazuhiko; Ueki, Keisuke; Nonaka, Masahiro; Asai, Akio; Kawahara, Nobutaka; Hirose, Yuichi; Takayama, Tatusya; Nakazato, Yoichi; Narita, Yoshitaka; Shibata, Tatsuhiro; Matsutani, Masao; Ushijima, Toshikazu; Nishikawa, Ryo; Ichimura, Koichi; On behalf of The Intracranial Germ Cell Tumor Genome Analysis Consortium (The iGCTConsortium)
profiling. ...
... DNA  methylation 
The Role of DNA Methylation in Hypertension
The Role of DNA Methylation in Hypertension
Demura, Masashi; Saijoh, Kiyofumi
is the covalent modification of DNA that ...
... Gene-specific  methylation 
Methylation profiling of 48 candidate genes in tumor and matched normal tissues from breast cancer patients
Methylation profiling of 48 candidate genes in tumor and matched normal tissues from breast cancer patients
Li, Zibo; Guo, Xinwu; Wu, Yepeng; Li, Shengyun; Yan, Jinhua; Peng, Limin; Xiao, Zhi; Wang, Shouman; Deng, Zhongping; Dai, Lizhong; Yi, Wenjun; Xia, Kun; Tang, Lili; Wang, Jun
alterations in breast cancer have been ...
... study was to investigate MGMT promoter  methylation 
MGMT promoter methylation and immunoexpression in aggressive pituitary adenomas and carcinomas
MGMT promoter methylation and immunoexpression in aggressive pituitary adenomas and carcinomas
Salehi, Fateme; Scheithauer, Bernd W.; Kros, Johann M.; Lau, Queenie; Fealey, Michael; Erickson, Dana; Kovacs, Kalman; Horvath, Eva; Lloyd, Ricardo V.
and immunoexpression in an aggressive ...
... We performed MethyLight analysis for the  methylation 
Promoter CpG island hypermethylation during breast cancer progression
Promoter CpG island hypermethylation during breast cancer progression
Park, So Yeon; Kwon, Hyeong Ju; Lee, Hee Eun; Ryu, Han Suk; Kim, Sung-Won; Kim, Jee Hyun; Kim, In Ah; Jung, Namhee; Cho, Nam-Yun; Kang, Gyeong Hoon
status of 57 promoter CpG island loci in ...
... Background DNA  methylation 
DNA Methylation in the Rectal Mucosa Is Associated with Crypt Proliferation and Fecal Short-Chain Fatty Acids
DNA Methylation in the Rectal Mucosa Is Associated with Crypt Proliferation and Fecal Short-Chain Fatty Acids
Worthley, Daniel L.; Whitehall, Vicki L. J.; Leu, Richard K.; Irahara, Natsumi; Buttenshaw, Ronald L.; Mallitt, Kylie-Ann; Greco, Sonia A.; Ramsnes, Ingunn; Winter, Jean; Hu, Ying; Ogino, Shuji; Young, Graeme P.; Leggett, Barbara A.
varies throughout the normal colorectal ...
... Purpose To explore differential  methylation 
Methylation of PITX2, HOXD3, RASSF1 and TDRD1 predicts biochemical recurrence in high-risk prostate cancer
Methylation of PITX2, HOXD3, RASSF1 and TDRD1 predicts biochemical recurrence in high-risk prostate cancer
Litovkin, Kirill; Joniau, Steven; Lerut, Evelyne; Laenen, Annouschka; Gevaert, Olivier; Spahn, Martin; Kneitz, Burkhard; Isebaert, Sofie; Haustermans, Karin; Beullens, Monique; Eynde, Aleyde; Bollen, Mathieu
of HAAO, HOXD3, LGALS3, PITX2, RASSF1 and ...
... Reportedly, the pyrosequencing  methylation 
Methylation status of long interspersed element-1 in advanced gastric cancer and its prognostic implication
Methylation status of long interspersed element-1 in advanced gastric cancer and its prognostic implication
Song, Young Seok; Kim, Younghoon; Cho, Nam Yun; Yang, Han Kwang; Kim, Woo Ho; Kang, Gyeong Hoon
assay can produce inconsistent results ...