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... Epigenetic biomarkers, such as DNA  methylation 
Epigenetic Biomarkers of Breast Cancer Risk: Across the Breast Cancer Prevention Continuum
Epigenetic Biomarkers of Breast Cancer Risk: Across the Breast Cancer Prevention Continuum
Terry, Mary Beth; McDonald, Jasmine A.; Wu, Hui Chen; Eng, Sybil; Santella, Regina M.
, can increase cancer risk through ...
... for a mechanistic link between DNA  methylation 
Methylation in Colorectal Cancer
Methylation in Colorectal Cancer
Mokarram, Pooneh; Estiar, Mehrdad Asghari; Ashktorab, Hassan
and histone deacetylation has also been ...
... of gene-specific and genomic DNA  methylation 
Blood-Derived DNA Methylation Markers of Cancer Risk
Blood-Derived DNA Methylation Markers of Cancer Risk
Marsit, Carmen; Christensen, Brock
has been extensively characterized in ...
... modifications, particularly DNA  methylation 
DNA methylation markers in colorectal cancer
DNA methylation markers in colorectal cancer
Kim, Myoung Sook; Lee, Juna; Sidransky, David
in selected gene promoters, are ...
... around CpG islands. It is unclear whether  methylation 
Characterization of human gastric carcinoma-related methylation of 9 miR CpG islands and repression of their expressions in vitro and in vivo
Characterization of human gastric carcinoma-related methylation of 9 miR CpG islands and repression of their expressions in vitro and in vivo
Du, Yantao; Liu, Zhaojun; Gu, Liankun; Zhou, Jing; Zhu, Bu-dong; Ji, Jiafu; Deng, Dajun
of these CpG islands represses miR ...
... Background Aberrant DNA  methylation 
DNA methylation analysis reveals distinct methylation signatures in pediatric germ cell tumors
DNA methylation analysis reveals distinct methylation signatures in pediatric germ cell tumors
Amatruda, James F; Ross, Julie A; Christensen, Brock; Fustino, Nicholas J; Chen, Kenneth S; Hooten, Anthony J; Nelson, Heather; Kuriger, Jacquelyn K; Rakheja, Dinesh; Frazier, A Lindsay; Poynter, Jenny N
is a prominent feature of many cancers, ...
... driver of tumorigenesis, and DNA  methylation 
DNA methylation in ductal carcinoma in situof the breast
DNA methylation in ductal carcinoma in situof the breast
Pang, Jia-Min B; Dobrovic, Alexander; Fox, Stephen B
of specific gene promoters provides ...
... present in the epigenome, in DNA  methylation 
Epigenetic Epidemiology for Cancer Risk: Harnessing Germline Epigenetic Variation
Epigenetic Epidemiology for Cancer Risk: Harnessing Germline Epigenetic Variation
Brennan, Kevin; Flanagan, James M.
as well as histone modifications, which ...
... global DNA hypomethylation. Aberrant DNA  methylation 
Hypermethylation of CDKN2A exon 2 in tumor, tumor-adjacent and tumor-distant tissues from breast cancer patients
Hypermethylation of CDKN2A exon 2 in tumor, tumor-adjacent and tumor-distant tissues from breast cancer patients
Spitzwieser, Melanie; Entfellner, Elisabeth; Werner, Bettina; Pulverer, Walter; Pfeiler, Georg; Hacker, Stefan; Cichna-Markl, Margit
levels have, however, not only been found ...
... DNA  methylation 
Integrative Analysis Identifies Transcription Factor–DNA Methylation Relationships and Introduces New Avenues for Translating Cancer Epigenetics into the Clinic
Integrative Analysis Identifies Transcription Factor–DNA Methylation Relationships and Introduces New Avenues for Translating Cancer Epigenetics into the Clinic
Ung, Matthew H.; Lou, Shaoke; Varn, Frederick S.; Cheng, Chao
is essential in the regulation of gene ...
... poor patient’s prognosis. Beside promoter  methylation 
Epigenetic modulation of the drug resistance genes MGMT, ABCB1 and ABCG2 in glioblastoma multiforme
Epigenetic modulation of the drug resistance genes MGMT, ABCB1 and ABCG2 in glioblastoma multiforme
Oberstadt, Moritz C; Bien-Möller, Sandra; Weitmann, Kerstin; Herzog, Susann; Hentschel, Katharina; Rimmbach, Christian; Vogelgesang, Silke; Balz, Ellen; Fink, Matthias; Michael, Heike; Zeden, Jan-Philip; Bruckmüller, Henrike; Werk, Anneke N; Cascorbi, Ingolf; Hoffmann, Wolfgang; Rosskopf, Dieter; Schroeder, Henry WS; Kroemer, Heyo K
of the O 6 ...
... to investigate the applicability of the  methylation 
Applicability of HIN-1, MGMT and RASSF1A promoter methylation as biomarkers for detecting field cancerization in breast cancer
Applicability of HIN-1, MGMT and RASSF1A promoter methylation as biomarkers for detecting field cancerization in breast cancer
Spitzwieser, Melanie; Holzweber, Elisabeth; Pfeiler, Georg; Hacker, Stefan; Cichna-Markl, Margit
status of six tumor suppressor genes as ...
... this sense, epigenetics, specifically DNA  methylation 
Epigenetics of Breast Cancer: DNA Methylome and Global Histone Modifications
Epigenetics of Breast Cancer: DNA Methylome and Global Histone Modifications
Mese, Gulistan; Yalcin-Ozuysal, Ozden
and histone modifications, have emerged ...
... evidence on the prognostic utility of DNA  methylation 
Methylation markers for prostate cancer prognosis: a systematic review
Methylation markers for prostate cancer prognosis: a systematic review
Chao, Chun; Chi, Margaret; Preciado, Melissa; Black, Mary Helen
markers in prostate cancer and ascertain ...
... potential for the development of new DNA  methylation 
A panel of genes methylated with high frequency in colorectal cancer
A panel of genes methylated with high frequency in colorectal cancer
Mitchell, Susan M; Ross, Jason P; Drew, Horace R; Ho, Thu; Brown, Glenn S; Saunders, Neil FW; Duesing, Konsta R; Buckley, Michael J; Dunne, Rob; Beetson, Iain; Rand, Keith N; McEvoy, Aidan; Thomas, Melissa L; Baker, Rohan T; Wattchow, David A; Young, Graeme P; Lockett, Trevor J; Pedersen, Susanne K; LaPointe, Lawrence C; Molloy, Peter L
biomarkers or panels to improve the ...
... array-based analysis of genome-wide DNA  methylation 
Global, cancer-specific microRNA cluster hypomethylation was functionally associated with the development of non-B non-C hepatocellular carcinoma
Global, cancer-specific microRNA cluster hypomethylation was functionally associated with the development of non-B non-C hepatocellular carcinoma
Nojima, Masanori; Matsui, Takeshi; Tamori, Akihiro; Kubo, Shoji; Shirabe, Ken; Kimura, Koichi; Shimada, Mitsuo; Utsunomiya, Tohru; Kondo, Yasuteru; Iio, Etsuko; Naito, Yutaka; Ochiya, Takahiro; Tanaka, Yasuhito
(N = 43 pairs) and mRNA/miRNA expression ...
... DNA  methylation 
Lung cancer: From single-gene methylation to methylome profiling
Lung cancer: From single-gene methylation to methylome profiling
Heller, Gerwin; Zielinski, Christoph C.; Zöchbauer-Müller, Sabine
as part of the epigenetic gene-silencing ...
... prostate cancer. In breast cancer, DNA  methylation 
Epigenetics in Breast and Prostate Cancer
Epigenetics in Breast and Prostate Cancer
Wu, Yanyuan; Sarkissyan, Marianna; Vadgama, Jaydutt V.
profiles have been linked to hormone ...
... microarrays to compare genomewide  methylation 
Identification and characterization of locus-specific methylation patterns within novel loci undergoing hypermethylation during breast cancer pathogenesis
Identification and characterization of locus-specific methylation patterns within novel loci undergoing hypermethylation during breast cancer pathogenesis
Wojdacz, Tomasz K; Windeløv, Johanne A; Thestrup, Britta B; Damsgaard, Tine E; Overgaard, Jens; Hansen, Lise Lotte
patterns of breast carcinomas (n = 20) ...
... Background Aberrant DNA  methylation 
An integrated genomics analysis of epigenetic subtypes in human breast tumors links DNA methylation patterns to chromatin states in normal mammary cells
An integrated genomics analysis of epigenetic subtypes in human breast tumors links DNA methylation patterns to chromatin states in normal mammary cells
Holm, Karolina; Staaf, Johan; Lauss, Martin; Aine, Mattias; Lindgren, David; Bendahl, Pär-Ola; Vallon-Christersson, Johan; Barkardottir, Rosa Bjork; Höglund, Mattias; Borg, Åke; Jönsson, Göran; Ringnér, Markus
is frequently observed in breast cancer. ...
... two decades. In particular, aberrant DNA  methylation 
Mechanisms for the induction of gastric cancer by Helicobacter pylori infection: aberrant DNA methylation pathway
Mechanisms for the induction of gastric cancer by Helicobacter pylori infection: aberrant DNA methylation pathway
Maeda, Masahiro; Moro, Hiroshi; Ushijima, Toshikazu
is induced in multiple driver genes, ...
... as epigenetically silenced by promotor  methylation 
The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma
The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma
Djos, Anna; Martinsson, Tommy; Kogner, Per; Carén, Helena
in human cancers. ...
... has been shown to occur in cancer; DNA  methylation 
IGF-II promoter methylation and ovarian cancer prognosis
IGF-II promoter methylation and ovarian cancer prognosis
Beeghly, A. C.; Katsaros, D.; Wiley, A. L.; Rigault de la Longrais, I. A.; Prescott, A. T.; Chen, H.; Puopolo, M.; Rutherford, T. J.; Yu, H.
regulates promoter use. ...
... cancer, we attempted to identify the  methylation 
Methylation in promoter regions of PITX2 and RASSF1A genes in association with clinicopathological features in breast cancer patients
Methylation in promoter regions of PITX2 and RASSF1A genes in association with clinicopathological features in breast cancer patients
Jezkova, Eva; Kajo, Karol; Zubor, Pavol; Grendar, Marian; Malicherova, Bibiana; Mendelova, Andrea; Dokus, Karol; Lasabova, Zora; Plank, Lukas; Danko, Jan
status of key tumour suppressor gene Ras ...
... of epigenetic alterations (mainly DNA  methylation 
Epigenetics and Three Main Clinical Aspects of Breast Cancer Management
Epigenetics and Three Main Clinical Aspects of Breast Cancer Management
Izadi, Pantea; Noruzinia, Mehrdad
) in these three clinical problems of ...

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