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... cancer, we attempted to identify the  methylation 
Methylation in promoter regions of PITX2 and RASSF1A genes in association with clinicopathological features in breast cancer patients
Methylation in promoter regions of PITX2 and RASSF1A genes in association with clinicopathological features in breast cancer patients
Jezkova, Eva; Kajo, Karol; Zubor, Pavol; Grendar, Marian; Malicherova, Bibiana; Mendelova, Andrea; Dokus, Karol; Lasabova, Zora; Plank, Lukas; Danko, Jan
status of key tumour suppressor gene Ras ...
... Aberrant DNA  methylation 
The specific methylation characteristics of cancer related genes in Chinese colorectal cancer patients
The specific methylation characteristics of cancer related genes in Chinese colorectal cancer patients
Yang, WenJie; Wang, XiaoFeng; Li, XiaoWei; Wang, Min; Chen, XiaoFeng; Wu, XiaoMei; Wang, YaPing; Fan, YiMei; Jin, HeiYing
at CpG islands has been implicated as a ...
... the evaluation of the profile of promoter  methylation 
The methylation of a panel of genes differentiates low-grade from high-grade gliomas
The methylation of a panel of genes differentiates low-grade from high-grade gliomas
Majchrzak-Celińska, Aleksandra; Paluszczak, Jarosław; Szalata, Marlena; Barciszewska, Anna-Maria; Nowak, Stanisław; Kleszcz, Robert; Sherba, Adam; Baer-Dubowska, Wanda
of 13 genes selected based on their ...
... squamous cell carcinoma (ESCC). The  methylation 
PTEN gene is infrequently hypermethylated in human esophageal squamous cell carcinoma
PTEN gene is infrequently hypermethylated in human esophageal squamous cell carcinoma
Sun, Zhenguo; Ji, Na; Bi, Mingming; Wang, Shuai; Liu, Xiangyan; Wang, Zhou
status of PTEN gene was evaluated in 74 ...
... samples. We further proceeded to promoter  methylation 
Epigenetic regulation of human hedgehog interacting protein in glioma cell lines and primary tumor samples
Epigenetic regulation of human hedgehog interacting protein in glioma cell lines and primary tumor samples
Shahi, Mehdi H.; Zazpe, Idoya; Afzal, Mohammad; Sinha, Subrata; Rebhun, Robert B.; Meléndez, Bárbara; Rey, Juan A.; Castresana, Javier S.
study of this gene in the same cell lines ...
... (MGMT)  methylation 
Prognostic value of MGMT methylation in colorectal cancer: a meta-analysis and literature review
Prognostic value of MGMT methylation in colorectal cancer: a meta-analysis and literature review
Li, Yanliang; Lyu, Zhongchuan; Zhao, Lixin; Cheng, Hong; Zhu, Dongyuan; Gao, Yongsheng; Shang, Xiuwan; Shi, Huaijie
as a potential prognostic factor in CRC, ...
... methylator phenotype (CIMP) involves  methylation 
CpG island methylator phenotype of multigene in serum of sporadic breast carcinoma
CpG island methylator phenotype of multigene in serum of sporadic breast carcinoma
Jing, Feng; Yuping, Wang; Yong, Chen; Jie, Luo; Jun, Lu; Xuanbing, Tang; Lihua, Hu
targeted toward the promoters of multiple ...
... Both hepatitis B virus (HBV) and gene  methylation 
Promoter hypermethylation of p14ARF, RB, and INK4 gene family in hepatocellular carcinoma with hepatitis B virus infection
Promoter hypermethylation of p14ARF, RB, and INK4 gene family in hepatocellular carcinoma with hepatitis B virus infection
Zhang, Ji-Cai; Gao, Bo; Yu, Zong-Tao; Liu, Xiao-Bo; Lu, Jun; Xie, Fei; Luo, Hai-Jun; Li, Hai-Ping
play important roles in ...
... of p16 and hMLH1 genes simultaneous  methylation 
Combined methylation of p16 and hMLH1 (CMETH2) discriminates a subpopulation with better prognosis in colorectal cancer patients with microsatellite instability tumors
Combined methylation of p16 and hMLH1 (CMETH2) discriminates a subpopulation with better prognosis in colorectal cancer patients with microsatellite instability tumors
Veganzones, S.; Maestro, M. L.; Rafael, S.; Orden, V.; Vidaurreta, M.; Mediero, B.; Espantaleón, M.; Cerdán, J.; Díaz-Rubio, E.
in colorectal cancer patients with ...
... and clinical behavior. In terms of DNA  methylation 
Hypermethylation in bladder cancer: biological pathways and translational applications
Hypermethylation in bladder cancer: biological pathways and translational applications
Sánchez-Carbayo, Marta
, cancer cells show genome-wide ...
... chain reaction to examine RASSF10  methylation 
The value of serum RASSF10 hypermethylation as a diagnostic and prognostic tool for gastric cancer
The value of serum RASSF10 hypermethylation as a diagnostic and prognostic tool for gastric cancer
Xue, Wan-Jiang; Feng, Ying; Wang, Fei; Li, Peng; Liu, Yi-Fei; Guo, Yi-Bing; Wang, Zhi-Wei; Mao, Qin-Sheng
levels in serum and/or tumor samples from ...
... the association between RASSF1A promoter  methylation 
Association of RASSF1A promoter methylation with gastric cancer risk: a meta-analysis
Association of RASSF1A promoter methylation with gastric cancer risk: a meta-analysis
Shi, Dong-Tao; Han, Mei; Gao, Nan; Tian, Wenyan; Chen, Weichang
and gastric cancer risk remains ...
... the relationship between DLC-1  methylation 
DLC-1 is a candidate biomarker methylated and down-regulated in pancreatic ductal adenocarcinoma
DLC-1 is a candidate biomarker methylated and down-regulated in pancreatic ductal adenocarcinoma
Xue, Yu-Zheng; Wu, Tie-Long; Wu, Yan-Min; Sheng, Ying-Yue; Wei, Zhe-Qiang; Lu, Yu-Feng; Yu, Li-Hua; Li, Jian-Ping; Li, Zhao-Shen
status and clinicopathological ...
... that tazarotene-induced gene 1 (TIG1)  methylation 
Aberrant TIG1 methylation associated with its decreased expression and clinicopathological significance in hepatocellular carcinoma
Aberrant TIG1 methylation associated with its decreased expression and clinicopathological significance in hepatocellular carcinoma
Chen, Xi-Hua; Wu, Wen-Guang; Ding, Jian
was frequently detected in a variety of ...
... p15 INK4b and p16 INK4a aberrant promoter  methylation 
Aberrant promoter methylation of p15INK4b and p16INK4a genes may contribute to the pathogenesis of multiple myeloma: a meta-analysis
Aberrant promoter methylation of p15INK4b and p16INK4a genes may contribute to the pathogenesis of multiple myeloma: a meta-analysis
Wang, Xuan; Zhu, Yan-Bin; Cui, Hai-Peng; Yu, Ting-Ting
in the pathogenesis of multiple myeloma ...
... reaction and Western blot analysis, DNA  methylation 
Promoter methylation-mediated downregulation of PRDM5 contributes to the development of lung squamous cell carcinoma
Promoter methylation-mediated downregulation of PRDM5 contributes to the development of lung squamous cell carcinoma
Tan, Shuang-Xiang; Hu, Rui-Cheng; Tan, Yong-Li; Liu, Jing-Jing; Liu, Wen-En
of PRDM5 promoter was analyzed by ...
... clear. In this study, we investigated DNA  methylation 
Aberrant DNA methylation of integrin α4 in human breast cancer
Aberrant DNA methylation of integrin α4 in human breast cancer
Do, Sung-Im; Ko, Eunkyung; Kang, So Young; Lee, Jeong Eon; Nam, Seok Jin; Cho, Eun Yoon; Kim, Duk-Hwan
of integrin α4 in breast cancer. ...
... polymerase chain reaction (qRT-PCR).  Methylation 
Abnormal hypermethylation and clinicopathological significance of FBLN1 gene in cutaneous melanoma
Abnormal hypermethylation and clinicopathological significance of FBLN1 gene in cutaneous melanoma
Wu, Bao-Jin; Zhou, Zhao-Ping; Li, Wen-Peng; Ding, Wei; Wu, Ying-Zhi; Zhou, Zhong-Wen; Zhang, Rong-Qing; Liu, Qing-Feng; Jiang, Hua
-specific polymerase chain reaction was ...
... to be associated with tumorigenesis.  Methylation 
Promoter methylation and expression of CDH1 and susceptibility and prognosis of eyelid squamous cell carcinoma
Promoter methylation and expression of CDH1 and susceptibility and prognosis of eyelid squamous cell carcinoma
Wang, Yong-Qiang; Yuan, Ye; Jiang, Shan; Jiang, Hua
of CDH1 promotors can alter the ...
... studies to evaluate whether promoter  methylation 
Aberrant promoter methylation of HIN-1 gene may contribute to the pathogenesis of breast cancer: a meta-analysis
Aberrant promoter methylation of HIN-1 gene may contribute to the pathogenesis of breast cancer: a meta-analysis
Dai, Di; Dong, Xi-Hua; Cheng, Shi-Tong; Zhu, Ge; Guo, Xiao-Lin
of the high in normal-1 (HIN-1) gene ...
... conducted to evaluate whether promoter  methylation 
Aberrant promoter methylation of the SFRP1 gene may contribute to colorectal carcinogenesis: a meta-analysis
Aberrant promoter methylation of the SFRP1 gene may contribute to colorectal carcinogenesis: a meta-analysis
Chen, Yan-Zhi; Liu, Dan; Zhao, Yu-Xia; Wang, He-Tong; Gao, Ya; Chen, Ying
of the secreted frizzled-related protein ...
... the occurrence and relevance of promoter  methylation 
Methylation of the APAF-1 and DAPK-1 promoter region correlates with progression of renal cell carcinoma in North Indian population
Methylation of the APAF-1 and DAPK-1 promoter region correlates with progression of renal cell carcinoma in North Indian population
Ahmad, Shiekh Tanveer; Arjumand, Wani; Seth, Amlesh; Saini, Ashish Kumar; Sultana, Sarwat
of the tumor suppressor DAPK-1, APAF-1 () ...
... cancer detection. To evaluate the  methylation 
Methylation analysis of plasma cell-free DNA for breast cancer early detection using bisulfite next-generation sequencing
Methylation analysis of plasma cell-free DNA for breast cancer early detection using bisulfite next-generation sequencing
Li, Zibo; Guo, Xinwu; Tang, Lili; Peng, Limin; Chen, Ming; Luo, Xipeng; Wang, Shouman; Xiao, Zhi; Deng, Zhongping; Dai, Lizhong; Xia, Kun; Wang, Jun
levels of six candidate genes (EGFR, ...
... The protein expression and promoter  methylation 
Promoter methylation and immunohistochemical expression of hMLH1 and hMSH2 in sporadic colorectal cancer: a study from India
Promoter methylation and immunohistochemical expression of hMLH1 and hMSH2 in sporadic colorectal cancer: a study from India
Malhotra, Pooja; Anwar, Mumtaz; Kochhar, Rakesh; Ahmad, Shabeer; Vaiphei, Kim; Mahmood, Safrun
of hMLH1 and hMSH2; Mismatch Repair genes ...
... demethylating agents. In this study, the  methylation 
Methylation of the p73 gene in patients with myelodysplastic syndromes: correlations with apoptosis and prognosis
Methylation of the p73 gene in patients with myelodysplastic syndromes: correlations with apoptosis and prognosis
Zhao, Youshan; Fei, Chengming; Zhang, Xi; Zhang, Yao; Guo, Juan; Gu, Shucheng; Li, Xiao; Chang, Chunkang
status of the p73 gene promoter was ...