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... with relatively high levels of CpG island  methylation 
Methylation kinetics and CpG-island methylator phenotyope status in colorectal cancer cell lines
Methylation kinetics and CpG-island methylator phenotyope status in colorectal cancer cell lines
Wodarz, Dominik; Boland, C Richard; Goel, Ajay; Komarova, Natalia L
are considered CpG island methylator ...
... Background Gene body  methylation 
Proximal methylation features associated with nonrandom changes in gene body methylation
Proximal methylation features associated with nonrandom changes in gene body methylation
Picard, Colette L.; Gehring, Mary
at CG dinucleotides is a widely conserved ...
... Epigenetic biomarkers, such as DNA  methylation 
Epigenetic Biomarkers of Breast Cancer Risk: Across the Breast Cancer Prevention Continuum
Epigenetic Biomarkers of Breast Cancer Risk: Across the Breast Cancer Prevention Continuum
Terry, Mary Beth; McDonald, Jasmine A.; Wu, Hui Chen; Eng, Sybil; Santella, Regina M.
, can increase cancer risk through ...
... Background Aberrant DNA  methylation 
DNA methylation analysis reveals distinct methylation signatures in pediatric germ cell tumors
DNA methylation analysis reveals distinct methylation signatures in pediatric germ cell tumors
Amatruda, James F; Ross, Julie A; Christensen, Brock; Fustino, Nicholas J; Chen, Kenneth S; Hooten, Anthony J; Nelson, Heather; Kuriger, Jacquelyn K; Rakheja, Dinesh; Frazier, A Lindsay; Poynter, Jenny N
is a prominent feature of many cancers, ...
... exposures are associated with DNA-  methylation 
Environmental chemicals and DNA methylation in adults: a systematic review of the epidemiologic evidence
Environmental chemicals and DNA methylation in adults: a systematic review of the epidemiologic evidence
Ruiz-Hernandez, Adrian; Kuo, Chin-Chi; Rentero-Garrido, Pilar; Tang, Wan-Yee; Redon, Josep; Ordovas, Jose M; Navas-Acien, Ana; Tellez-Plaza, Maria
and expression changes that can impact ...
... Background DNA cytosine  methylation 
Dynamic DNA cytosine methylation in the Populus trichocarpa genome: tissue-level variation and relationship to gene expression
Dynamic DNA cytosine methylation in the Populus trichocarpa genome: tissue-level variation and relationship to gene expression
Vining, Kelly J; Pomraning, Kyle R; Wilhelm, Larry J; Priest, Henry D; Pellegrini, Matteo; Mockler, Todd C; Freitag, Michael; Strauss, Steven H
is an epigenetic modification that has ...
... Background DNA  methylation 
Widespread natural variation of DNA methylation within angiosperms
Widespread natural variation of DNA methylation within angiosperms
Niederhuth, Chad E.; Bewick, Adam J.; Ji, Lexiang; Alabady, Magdy S.; Kim, Kyung Do; Li, Qing; Rohr, Nicholas A.; Rambani, Aditi; Burke, John M.; Udall, Joshua A.; Egesi, Chiedozie; Schmutz, Jeremy; Grimwood, Jane; Jackson, Scott A.; Springer, Nathan M.; Schmitz, Robert J.
is an important feature of plant ...
... Background DNA  methylation 
Tissue-specific variation in DNA methylation levels along human chromosome 1
Tissue-specific variation in DNA methylation levels along human chromosome 1
De Bustos, Cecilia; Ramos, Edward; Young, Janet M; Tran, Robert K; Menzel, Uwe; Langford, Cordelia F; Eichler, Evan E; Hsu, Li; Henikoff, Steve; Dumanski, Jan P; Trask, Barbara J
is a major epigenetic modification ...
... Background  Methylation 
Hypomethylation coordinates antagonistically with hypermethylation in cancer development: a case study of leukemia
Hypomethylation coordinates antagonistically with hypermethylation in cancer development: a case study of leukemia
Kushwaha, Garima; Dozmorov, Mikhail; Wren, Jonathan D.; Qiu, Jing; Shi, Huidong; Xu, Dong
changes are frequent in cancers, but ...
... and persistence of sex differences in DNA  methylation 
The effects of perinatal testosterone exposure on the DNA methylome of the mouse brain are late-emerging
The effects of perinatal testosterone exposure on the DNA methylome of the mouse brain are late-emerging
Ghahramani, Negar M; Ngun, Tuck C; Chen, Pao-Yang; Tian, Yuan; Krishnan, Sangitha; Muir, Stephanie; Rubbi, Liudmilla; Arnold, Arthur P; de Vries, Geert J; Forger, Nancy G; Pellegrini, Matteo; Vilain, Eric
, we performed genome-wide surveys in ...
... Background DNA  methylation 
Distinct roles of DNMT1-dependent and DNMT1-independent methylation patterns in the genome of mouse embryonic stem cells
Distinct roles of DNMT1-dependent and DNMT1-independent methylation patterns in the genome of mouse embryonic stem cells
Li, Zhiguang; Dai, Hongzheng; Martos, Suzanne N.; Xu, Beisi; Gao, Yang; Li, Teng; Zhu, Guangjing; Schones, Dustin E.; Wang, Zhibin
patterns are initiated by de novo DNA ...
... regulation of gene expression through DNA  methylation 
Genetic analysis of DNA methylation and gene expression levels in whole blood of healthy human subjects
Genetic analysis of DNA methylation and gene expression levels in whole blood of healthy human subjects
van Eijk, Kristel R; de Jong, Simone; Boks, Marco PM; Langeveld, Terry; Colas, Fabrice; Veldink, Jan H; de Kovel, Carolien GF; Janson, Esther; Strengman, Eric; Langfelder, Peter; Kahn, René S; van den Berg, Leonard H; Horvath, Steve; Ophoff, Roel A
is an inverse association in which ...
... analysis of the genome-wide DNA  methylation 
A comparative analysis of DNA methylation across human embryonic stem cell lines
A comparative analysis of DNA methylation across human embryonic stem cell lines
Chen, Pao-Yang; Feng, Suhua; Joo, Jong Wha Joanne; Jacobsen, Steve E; Pellegrini, Matteo
profiles from three human embryonic stem ...
... where the epigenetic marks of DNA  methylation 
Placental methylome analysis from a prospective autism study
Placental methylome analysis from a prospective autism study
Schroeder, Diane I.; Schmidt, Rebecca J.; Crary-Dooley, Florence K.; Walker, Cheryl K.; Ozonoff, Sally; Tancredi, Daniel J.; Hertz-Picciotto, Irva; LaSalle, Janine M.
may be useful as risk biomarkers. ...
... nucleotides across an organism’s genome (  methylation 
DNA methylation and gene expression in Mimulus guttatus
DNA methylation and gene expression in Mimulus guttatus
Colicchio, Jack M.; Miura, Fumihito; Kelly, John K.; Ito, Takashi; Hileman, Lena C.
) is a major regulator of genome ...
... for a mechanistic link between DNA  methylation 
Methylation in Colorectal Cancer
Methylation in Colorectal Cancer
Mokarram, Pooneh; Estiar, Mehrdad Asghari; Ashktorab, Hassan
and histone deacetylation has also been ...
... Identifying genetic loci where DNA  methylation 
DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases
DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases
Ligthart, Symen; Marzi, Carola; Aslibekyan, Stella; Mendelson, Michael M.; Conneely, Karen N.; Tanaka, Toshiko; Colicino, Elena; Waite, Lindsay L.; Joehanes, Roby; Guan, Weihua; Brody, Jennifer A.; Elks, Cathy; Marioni, Riccardo; Jhun, Min A.; Agha, Golareh; Bressler, Jan; Ward-Caviness, Cavin K.; Chen, Brian H.; Huan, Tianxiao; Bakulski, Kelly; Salfati, Elias L.; Fiorito, Giovanni; Wahl, Simone; Schramm, Katharina; Sha, Jin; Hernandez, Dena G.; Just, Allan C.; Smith, Jennifer A.; Sotoodehnia, Nona; Pilling, Luke C.; Pankow, James S.; Tsao, Phil S.; Liu, Chunyu; Zhao, Wei; Guarrera, Simonetta; Michopoulos, Vasiliki J.; Smith, Alicia K.; Peters, Marjolein J.; Melzer, David; Vokonas, Pantel; Fornage, Myriam; Prokisch, Holger; Bis, Joshua C.; Chu, Audrey Y.; Herder, Christian; Grallert, Harald; Yao, Chen; Shah, Sonia; McRae, Allan F.; Lin, Honghuang; Horvath, Steve; Fallin, Daniele; Hofman, Albert; Wareham, Nicholas J.; Wiggins, Kerri L.; Feinberg, Andrew P.; Starr, John M.; Visscher, Peter M.; Murabito, Joanne M.; Kardia, Sharon L. R.; Absher, Devin M.; Binder, Elisabeth B.; Singleton, Andrew B.; Bandinelli, Stefania; Peters, Annette; Waldenberger, Melanie; Matullo, Giuseppe; Schwartz, Joel D.; Demerath, Ellen W.; Uitterlinden, André G.; van Meurs, Joyce B. J.; Franco, Oscar H.; Chen, Yii-Der Ida; Levy, Daniel; Turner, Stephen T.; Deary, Ian J.; Ressler, Kerry J.; Dupuis, Josée; Ferrucci, Luigi; Ong, Ken K.; Assimes, Themistocles L.; Boerwinkle, Eric; Koenig, Wolfgang; Arnett, Donna K.; Baccarelli, Andrea A.; Benjamin, Emelia J.; Dehghan, Abbas; WHI-EMPC Investigators; CHARGE epigenetics of Coronary Heart Disease
is associated with chronic low-grade ...
... of gene-specific and genomic DNA  methylation 
Blood-Derived DNA Methylation Markers of Cancer Risk
Blood-Derived DNA Methylation Markers of Cancer Risk
Marsit, Carmen; Christensen, Brock
has been extensively characterized in ...
... Background DNA  methylation 
DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines
DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines
Bell, Jordana T; Pai, Athma A; Pickrell, Joseph K; Gaffney, Daniel J; Pique-Regi, Roger; Degner, Jacob F; Gilad, Yoav; Pritchard, Jonathan K
is an essential epigenetic mechanism ...
... for individual-specific genome-wide DNA  methylation 
Predicting genome-wide DNA methylation using methylation marks, genomic position, and DNA regulatory elements
Predicting genome-wide DNA methylation using methylation marks, genomic position, and DNA regulatory elements
Zhang, Weiwei; Spector, Tim D; Deloukas, Panos; Bell, Jordana T; Engelhardt, Barbara E
profiles have enabled epigenome-wide ...
... Background Changes in DNA  methylation 
Genome-wide survey reveals dynamic widespread tissue-specific changes in DNA methylation during development
Genome-wide survey reveals dynamic widespread tissue-specific changes in DNA methylation during development
Liang, Ping; Song, Fei; Ghosh, Srimoyee; Morien, Evan; Qin, Maochun; Mahmood, Saleh; Fujiwara, Kyoko; Igarashi, Jun; Nagase, Hiroki; Held, William A
in the mammalian genome during ...
... and the importance of aberrant DNA  methylation 
Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer
Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer
Heyn, Holger; Vidal, Enrique; Ferreira, Humberto J.; Vizoso, Miguel; Sayols, Sergi; Gomez, Antonio; Moran, Sebastian; Boque-Sastre, Raquel; Guil, Sonia; Martinez-Cardus, Anna; Lin, Charles Y.; Royo, Romina; Sanchez-Mut, Jose V.; Martinez, Ramon; Gut, Marta; Torrents, David; Orozco, Modesto; Gut, Ivo; Young, Richard A.; Esteller, Manel
profiles is increasingly recognized. ...
... that individual differences in SLC6A4 DNA  methylation 
Influence of life stress, 5-HTTLPR genotype, and SLC6A4 methylation on gene expression and stress response in healthy Caucasian males
Influence of life stress, 5-HTTLPR genotype, and SLC6A4 methylation on gene expression and stress response in healthy Caucasian males
Duman, Elif A; Canli, Turhan
could be one underlying mechanism by ...
... understood. Results Here, we profile CpG  methylation 
Trans effects of chromosome aneuploidies on DNA methylation patterns in human Down syndrome and mouse models
Trans effects of chromosome aneuploidies on DNA methylation patterns in human Down syndrome and mouse models
Mendioroz, Maite; Do, Catherine; Jiang, Xiaoling; Liu, Chunhong; Darbary, Huferesh K.; Lang, Charles F.; Lin, John; Thomas, Anna; Abu-Amero, Sayeda; Stanier, Philip; Temkin, Alexis; Yale, Alexander; Liu, Meng-Min; Li, Yang; Salas, Martha; Kerkel, Kristi; Capone, George; Silverman, Wayne; Yu, Y. Eugene; Moore, Gudrun; Wegiel, Jerzy; Tycko, Benjamin
in DS and control cerebral and cerebellar ...
... we investigated buccal cell DNA  methylation 
Physical activity, black carbon exposure, and DNA methylation in the FOXP3 promoter
Physical activity, black carbon exposure, and DNA methylation in the FOXP3 promoter
Lovinsky-Desir, Stephanie; Jung, Kyung Hwa; Jezioro, Jacqueline R.; Torrone, David Z.; de Planell-Saguer, Mariangels; Yan, Beizhan; Perera, Frederica P.; Rundle, Andrew G.; Perzanowski, Matthew S.; Chillrud, Steven N.; Miller, Rachel L.
of the forkhead box p3 (FOXP3) gene ...