|... with relatively high levels of CpG island
|Methylation kinetics and CpG-island methylator phenotyope status in colorectal cancer cell lines
Methylation kinetics and CpG-island methylator phenotyope status in colorectal cancer cell lines
Wodarz, Dominik; Boland, C Richard; Goel, Ajay; Komarova, Natalia L
|are considered CpG island methylator ...
|... Epigenetic biomarkers, such as DNA
|Epigenetic Biomarkers of Breast Cancer Risk: Across the Breast Cancer Prevention Continuum
Epigenetic Biomarkers of Breast Cancer Risk: Across the Breast Cancer Prevention Continuum
Terry, Mary Beth; McDonald, Jasmine A.; Wu, Hui Chen; Eng, Sybil; Santella, Regina M.
|, can increase cancer risk through ...
|... Background Aberrant DNA
|DNA methylation analysis reveals distinct methylation signatures in pediatric germ cell tumors
DNA methylation analysis reveals distinct methylation signatures in pediatric germ cell tumors
Amatruda, James F; Ross, Julie A; Christensen, Brock; Fustino, Nicholas J; Chen, Kenneth S; Hooten, Anthony J; Nelson, Heather; Kuriger, Jacquelyn K; Rakheja, Dinesh; Frazier, A Lindsay; Poynter, Jenny N
|is a prominent feature of many cancers, ...
|... exposures are associated with DNA-
|Environmental chemicals and DNA methylation in adults: a systematic review of the epidemiologic evidence
Environmental chemicals and DNA methylation in adults: a systematic review of the epidemiologic evidence
Ruiz-Hernandez, Adrian; Kuo, Chin-Chi; Rentero-Garrido, Pilar; Tang, Wan-Yee; Redon, Josep; Ordovas, Jose M; Navas-Acien, Ana; Tellez-Plaza, Maria
|and expression changes that can impact ...
|... Background DNA cytosine
|Dynamic DNA cytosine methylation in the Populus trichocarpa genome: tissue-level variation and relationship to gene expression
Dynamic DNA cytosine methylation in the Populus trichocarpa genome: tissue-level variation and relationship to gene expression
Vining, Kelly J; Pomraning, Kyle R; Wilhelm, Larry J; Priest, Henry D; Pellegrini, Matteo; Mockler, Todd C; Freitag, Michael; Strauss, Steven H
|is an epigenetic modification that has ...
|... Background DNA
|Widespread natural variation of DNA methylation within angiosperms
Widespread natural variation of DNA methylation within angiosperms
Niederhuth, Chad E.; Bewick, Adam J.; Ji, Lexiang; Alabady, Magdy S.; Kim, Kyung Do; Li, Qing; Rohr, Nicholas A.; Rambani, Aditi; Burke, John M.; Udall, Joshua A.; Egesi, Chiedozie; Schmutz, Jeremy; Grimwood, Jane; Jackson, Scott A.; Springer, Nathan M.; Schmitz, Robert J.
|is an important feature of plant ...
|... Background DNA
|Tissue-specific variation in DNA methylation levels along human chromosome 1
Tissue-specific variation in DNA methylation levels along human chromosome 1
De Bustos, Cecilia; Ramos, Edward; Young, Janet M; Tran, Robert K; Menzel, Uwe; Langford, Cordelia F; Eichler, Evan E; Hsu, Li; Henikoff, Steve; Dumanski, Jan P; Trask, Barbara J
|is a major epigenetic modification ...
|Hypomethylation coordinates antagonistically with hypermethylation in cancer development: a case study of leukemia
Hypomethylation coordinates antagonistically with hypermethylation in cancer development: a case study of leukemia
Kushwaha, Garima; Dozmorov, Mikhail; Wren, Jonathan D.; Qiu, Jing; Shi, Huidong; Xu, Dong
|changes are frequent in cancers, but ...
|... and persistence of sex differences in DNA
|The effects of perinatal testosterone exposure on the DNA methylome of the mouse brain are late-emerging
The effects of perinatal testosterone exposure on the DNA methylome of the mouse brain are late-emerging
Ghahramani, Negar M; Ngun, Tuck C; Chen, Pao-Yang; Tian, Yuan; Krishnan, Sangitha; Muir, Stephanie; Rubbi, Liudmilla; Arnold, Arthur P; de Vries, Geert J; Forger, Nancy G; Pellegrini, Matteo; Vilain, Eric
|, we performed genome-wide surveys in ...
|... Background DNA
|Distinct roles of DNMT1-dependent and DNMT1-independent methylation patterns in the genome of mouse embryonic stem cells
Distinct roles of DNMT1-dependent and DNMT1-independent methylation patterns in the genome of mouse embryonic stem cells
Li, Zhiguang; Dai, Hongzheng; Martos, Suzanne N.; Xu, Beisi; Gao, Yang; Li, Teng; Zhu, Guangjing; Schones, Dustin E.; Wang, Zhibin
|patterns are initiated by de novo DNA ...
|... regulation of gene expression through DNA
|Genetic analysis of DNA methylation and gene expression levels in whole blood of healthy human subjects
Genetic analysis of DNA methylation and gene expression levels in whole blood of healthy human subjects
van Eijk, Kristel R; de Jong, Simone; Boks, Marco PM; Langeveld, Terry; Colas, Fabrice; Veldink, Jan H; de Kovel, Carolien GF; Janson, Esther; Strengman, Eric; Langfelder, Peter; Kahn, René S; van den Berg, Leonard H; Horvath, Steve; Ophoff, Roel A
|is an inverse association in which ...
|... analysis of the genome-wide DNA
|A comparative analysis of DNA methylation across human embryonic stem cell lines
A comparative analysis of DNA methylation across human embryonic stem cell lines
Chen, Pao-Yang; Feng, Suhua; Joo, Jong Wha Joanne; Jacobsen, Steve E; Pellegrini, Matteo
|profiles from three human embryonic stem ...
|... where the epigenetic marks of DNA
|Placental methylome analysis from a prospective autism study
Placental methylome analysis from a prospective autism study
Schroeder, Diane I.; Schmidt, Rebecca J.; Crary-Dooley, Florence K.; Walker, Cheryl K.; Ozonoff, Sally; Tancredi, Daniel J.; Hertz-Picciotto, Irva; LaSalle, Janine M.
|may be useful as risk biomarkers. ...
|... nucleotides across an organism’s genome (
|DNA methylation and gene expression in Mimulus guttatus
DNA methylation and gene expression in Mimulus guttatus
Colicchio, Jack M.; Miura, Fumihito; Kelly, John K.; Ito, Takashi; Hileman, Lena C.
|) is a major regulator of genome ...
|... for a mechanistic link between DNA
|Methylation in Colorectal Cancer
Methylation in Colorectal Cancer
Mokarram, Pooneh; Estiar, Mehrdad Asghari; Ashktorab, Hassan
|and histone deacetylation has also been ...
|... Identifying genetic loci where DNA
|DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases
DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases
Ligthart, Symen; Marzi, Carola; Aslibekyan, Stella; Mendelson, Michael M.; Conneely, Karen N.; Tanaka, Toshiko; Colicino, Elena; Waite, Lindsay L.; Joehanes, Roby; Guan, Weihua; Brody, Jennifer A.; Elks, Cathy; Marioni, Riccardo; Jhun, Min A.; Agha, Golareh; Bressler, Jan; Ward-Caviness, Cavin K.; Chen, Brian H.; Huan, Tianxiao; Bakulski, Kelly; Salfati, Elias L.; Fiorito, Giovanni; Wahl, Simone; Schramm, Katharina; Sha, Jin; Hernandez, Dena G.; Just, Allan C.; Smith, Jennifer A.; Sotoodehnia, Nona; Pilling, Luke C.; Pankow, James S.; Tsao, Phil S.; Liu, Chunyu; Zhao, Wei; Guarrera, Simonetta; Michopoulos, Vasiliki J.; Smith, Alicia K.; Peters, Marjolein J.; Melzer, David; Vokonas, Pantel; Fornage, Myriam; Prokisch, Holger; Bis, Joshua C.; Chu, Audrey Y.; Herder, Christian; Grallert, Harald; Yao, Chen; Shah, Sonia; McRae, Allan F.; Lin, Honghuang; Horvath, Steve; Fallin, Daniele; Hofman, Albert; Wareham, Nicholas J.; Wiggins, Kerri L.; Feinberg, Andrew P.; Starr, John M.; Visscher, Peter M.; Murabito, Joanne M.; Kardia, Sharon L. R.; Absher, Devin M.; Binder, Elisabeth B.; Singleton, Andrew B.; Bandinelli, Stefania; Peters, Annette; Waldenberger, Melanie; Matullo, Giuseppe; Schwartz, Joel D.; Demerath, Ellen W.; Uitterlinden, André G.; van Meurs, Joyce B. J.; Franco, Oscar H.; Chen, Yii-Der Ida; Levy, Daniel; Turner, Stephen T.; Deary, Ian J.; Ressler, Kerry J.; Dupuis, Josée; Ferrucci, Luigi; Ong, Ken K.; Assimes, Themistocles L.; Boerwinkle, Eric; Koenig, Wolfgang; Arnett, Donna K.; Baccarelli, Andrea A.; Benjamin, Emelia J.; Dehghan, Abbas; WHI-EMPC Investigators; CHARGE epigenetics of Coronary Heart Disease
|is associated with chronic low-grade ...
|... of gene-specific and genomic DNA
|Blood-Derived DNA Methylation Markers of Cancer Risk
Blood-Derived DNA Methylation Markers of Cancer Risk
Marsit, Carmen; Christensen, Brock
|has been extensively characterized in ...
|... Background DNA
|DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines
DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines
Bell, Jordana T; Pai, Athma A; Pickrell, Joseph K; Gaffney, Daniel J; Pique-Regi, Roger; Degner, Jacob F; Gilad, Yoav; Pritchard, Jonathan K
|is an essential epigenetic mechanism ...
|... for individual-specific genome-wide DNA
|Predicting genome-wide DNA methylation using methylation marks, genomic position, and DNA regulatory elements
Predicting genome-wide DNA methylation using methylation marks, genomic position, and DNA regulatory elements
Zhang, Weiwei; Spector, Tim D; Deloukas, Panos; Bell, Jordana T; Engelhardt, Barbara E
|profiles have enabled epigenome-wide ...
|... Background Changes in DNA
|Genome-wide survey reveals dynamic widespread tissue-specific changes in DNA methylation during development
Genome-wide survey reveals dynamic widespread tissue-specific changes in DNA methylation during development
Liang, Ping; Song, Fei; Ghosh, Srimoyee; Morien, Evan; Qin, Maochun; Mahmood, Saleh; Fujiwara, Kyoko; Igarashi, Jun; Nagase, Hiroki; Held, William A
|in the mammalian genome during ...
|... and the importance of aberrant DNA
|Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer
Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer
Heyn, Holger; Vidal, Enrique; Ferreira, Humberto J.; Vizoso, Miguel; Sayols, Sergi; Gomez, Antonio; Moran, Sebastian; Boque-Sastre, Raquel; Guil, Sonia; Martinez-Cardus, Anna; Lin, Charles Y.; Royo, Romina; Sanchez-Mut, Jose V.; Martinez, Ramon; Gut, Marta; Torrents, David; Orozco, Modesto; Gut, Ivo; Young, Richard A.; Esteller, Manel
|profiles is increasingly recognized. ...
|... that individual differences in SLC6A4 DNA
|Influence of life stress, 5-HTTLPR genotype, and SLC6A4 methylation on gene expression and stress response in healthy Caucasian males
Influence of life stress, 5-HTTLPR genotype, and SLC6A4 methylation on gene expression and stress response in healthy Caucasian males
Duman, Elif A; Canli, Turhan
|could be one underlying mechanism by ...
|... understood. Results Here, we profile CpG
|Trans effects of chromosome aneuploidies on DNA methylation patterns in human Down syndrome and mouse models
Trans effects of chromosome aneuploidies on DNA methylation patterns in human Down syndrome and mouse models
Mendioroz, Maite; Do, Catherine; Jiang, Xiaoling; Liu, Chunhong; Darbary, Huferesh K.; Lang, Charles F.; Lin, John; Thomas, Anna; Abu-Amero, Sayeda; Stanier, Philip; Temkin, Alexis; Yale, Alexander; Liu, Meng-Min; Li, Yang; Salas, Martha; Kerkel, Kristi; Capone, George; Silverman, Wayne; Yu, Y. Eugene; Moore, Gudrun; Wegiel, Jerzy; Tycko, Benjamin
|in DS and control cerebral and cerebellar ...
|... Background DNA
|Postnatal epigenetic regulation of intestinal stem cells requires DNA methylation and is guided by the microbiome
Postnatal epigenetic regulation of intestinal stem cells requires DNA methylation and is guided by the microbiome
Yu, Da-Hai; Gadkari, Manasi; Zhou, Quan; Yu, Shiyan; Gao, Nan; Guan, Yongtao; Schady, Deborah; Roshan, Tony N.; Chen, Miao-Hsueh; Laritsky, Eleonora; Ge, Zhongqi; Wang, Hui; Chen, Rui; Westwater, Caroline; Bry, Lynn; Waterland, Robert A.; Moriarty, Chelsea; Hwang, Cindy; Swennes, Alton G.; Moore, Sean R.; Shen, Lanlan
|is an epigenetic mechanism central to ...
|... decisions remain clinical challenges. DNA
|DNA methylation in ductal carcinoma in situ related with future development of invasive breast cancer
DNA methylation in ductal carcinoma in situ related with future development of invasive breast cancer
Johnson, Kevin C.; Koestler, Devin C.; Fleischer, Thomas; Chen, Panpan; Jenson, Erik G.; Marotti, Jonathan D.; Onega, Tracy; Kristensen, Vessela N.; Christensen, Brock C.
|alterations are early events in the ...