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... Several studies have proved that DNA  methylation 
DNA methylation-based variation between human populations
DNA methylation-based variation between human populations
Kader, Farzeen; Ghai, Meenu
affects regulation of gene expression and ...
... Background Gene body  methylation 
Proximal methylation features associated with nonrandom changes in gene body methylation
Proximal methylation features associated with nonrandom changes in gene body methylation
Picard, Colette L.; Gehring, Mary
at CG dinucleotides is a widely conserved ...
... epigenome. In the female germline, DNA  methylation 
Transcription and chromatin determinants of de novo DNA methylation timing in oocytes
Transcription and chromatin determinants of de novo DNA methylation timing in oocytes
Gahurova, Lenka; Tomizawa, Shin-ichi; Smallwood, Sébastien A.; Stewart-Morgan, Kathleen R.; Saadeh, Heba; Kim, Jeesun; Andrews, Simon R.; Chen, Taiping; Kelsey, Gavin
is acquired late in oogenesis from an ...
... altering the genetic sequence itself. DNA  methylation 
The DNA Methylome: An Interface Between the Environment, Immunity, and Ageing
The DNA Methylome: An Interface Between the Environment, Immunity, and Ageing
McEwen, Lisa M.; Goodman, Sarah J.; Kobor, Michael S.; Jones, Meaghan J.
is arguably the most well-characterized ...
... rates of T2D and metabolic syndrome, with  methylation 
Tissue-specific methylation profile in obese patients with type 2 diabetes before and after Roux-en-Y gastric bypass
Tissue-specific methylation profile in obese patients with type 2 diabetes before and after Roux-en-Y gastric bypass
Sala, Priscila; Miranda Torrinhas, Raquel Susana Matos; Fonseca, Danielle Cristina; Ravacci, Graziela Rosa; Waitzberg, Dan Linetzky; Giannella-Neto, Daniel
profiles in promoter regions of genes in ...
... child development. We focus on DNA  methylation 
DNA Methylation: A Mediator Between Parenting Stress and Adverse Child Development?
DNA Methylation: A Mediator Between Parenting Stress and Adverse Child Development?
Mulder, Rosa H.; Rijlaarsdam, Jolien; IJzendoorn, Marinus H.
, as this epigenetic mechanism is most ...
... In contrast to mammals where DNA  methylation 
Locus-Specific DNA Methylation Analysis and Applications to Plants
Locus-Specific DNA Methylation Analysis and Applications to Plants
How-Kit, Alexandre; Teyssier, Emeline; Deleuze, Jean-François; Gallusci, Philippe
occurs near exclusively at CG ...
... genetic changes to gene expression, DNA  methylation 
Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome
Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome
Cheung, Warren A.; Shao, Xiaojian; Morin, Andréanne; Siroux, Valérie; Kwan, Tony; Ge, Bing; Aïssi, Dylan; Chen, Lu; Vasquez, Louella; Allum, Fiona; Guénard, Frédéric; Bouzigon, Emmanuelle; Simon, Marie-Michelle; Boulier, Elodie; Redensek, Adriana; Watt, Stephen; Datta, Avik; Clarke, Laura; Flicek, Paul; Mead, Daniel; Paul, Dirk S.; Beck, Stephan; Bourque, Guillaume; Lathrop, Mark; Tchernof, André; Vohl, Marie-Claude; Demenais, Florence; Pin, Isabelle; Downes, Kate; Stunnenberg, Hendrick G.; Soranzo, Nicole; Pastinen, Tomi; Grundberg, Elin
, and histone marks but these ...
... increasing evidence for inter-individual  methylation 
Regions of common inter-individual DNA methylation differences in human monocytes: genetic basis and potential function
Regions of common inter-individual DNA methylation differences in human monocytes: genetic basis and potential function
Schröder, Christopher; Leitão, Elsa; Wallner, Stefan; Schmitz, Gerd; Klein-Hitpass, Ludger; Sinha, Anupam; Jöckel, Karl-Heinz; Heilmann-Heimbach, Stefanie; Hoffmann, Per; Nöthen, Markus M.; Steffens, Michael; Ebert, Peter; Rahmann, Sven; Horsthemke, Bernhard
differences at CpG dinucleotides in the ...
... Background DNA  methylation 
Single-base resolution methylomes of upland cotton (Gossypium hirsutum L.) reveal epigenome modifications in response to drought stress
Single-base resolution methylomes of upland cotton (Gossypium hirsutum L.) reveal epigenome modifications in response to drought stress
Lu, Xuke; Wang, Xiaoge; Chen, Xiugui; Shu, Na; Wang, Junjuan; Wang, Delong; Wang, Shuai; Fan, Weili; Guo, Lixue; Guo, Xiaoning; Ye, Wuwei
, with a cryptic role in genome ...
... global DNA hypomethylation. Aberrant DNA  methylation 
Hypermethylation of CDKN2A exon 2 in tumor, tumor-adjacent and tumor-distant tissues from breast cancer patients
Hypermethylation of CDKN2A exon 2 in tumor, tumor-adjacent and tumor-distant tissues from breast cancer patients
Spitzwieser, Melanie; Entfellner, Elisabeth; Werner, Bettina; Pulverer, Walter; Pfeiler, Georg; Hacker, Stefan; Cichna-Markl, Margit
levels have, however, not only been found ...
... Aberrant DNA  methylation 
Aberrant DNA methylation in melanoma: biomarker and therapeutic opportunities
Aberrant DNA methylation in melanoma: biomarker and therapeutic opportunities
Micevic, Goran; Theodosakis, Nicholas; Bosenberg, Marcus
is an epigenetic hallmark of melanoma, ...
... Epigenetic events such as DNA-  methylation 
The Role of Epigenetics
The Role of Epigenetics
Kwabi-Addo, Bernard
changes have increasingly been found to ...
... Epigenetic modifications, among these DNA  methylation 
Dynamic DNA Methylation Patterns in Stress Response
Dynamic DNA Methylation Patterns in Stress Response
Viggiano, Luigi; Pinto, Maria Concetta
, represent potentially robust mechanisms ...
... in CF-affected tissues and (ii) DNA  methylation 
DNA methylation at modifier genes of lung disease severity is altered in cystic fibrosis
DNA methylation at modifier genes of lung disease severity is altered in cystic fibrosis
Magalhães, Milena; Rivals, Isabelle; Claustres, Mireille; Varilh, Jessica; Thomasset, Mélodie; Bergougnoux, Anne; Mely, Laurent; Leroy, Sylvie; Corvol, Harriet; Guillot, Loïc; Murris, Marlène; Beyne, Emmanuelle; Caimmi, Davide; Vachier, Isabelle; Chiron, Raphaël; De Sario, Albertina
variations at disease modifier genes ...
... DNA methylationEpigenetic therapy DNA  methylation 
Epigenetic Basis of Human Cancer
Epigenetic Basis of Human Cancer
Mikeska, Thomas; Dobrovic, Alexander
, histone modificationsEpigenetic therapy ...
... DNA  methylation 
Tools and Strategies for Analysis of Genome-Wide and Gene-Specific DNA Methylation Patterns
Tools and Strategies for Analysis of Genome-Wide and Gene-Specific DNA Methylation Patterns
Chatterjee, Aniruddha; Rodger, Euan J.; Morison, Ian M.; Eccles, Michael R.; Stockwell, Peter A.
is a stable epigenetic mechanism that has ...
... role in non-coding RNA-directed DNA  methylation 
The developmental regulator PKL is required to maintain correct DNA methylation patterns at RNA-directed DNA methylation loci
The developmental regulator PKL is required to maintain correct DNA methylation patterns at RNA-directed DNA methylation loci
Yang, Rong; Zheng, Zhimin; Chen, Qing; Yang, Lan; Huang, Huan; Miki, Daisuke; Wu, Wenwu; Zeng, Liang; Liu, Jun; Zhou, Jin-Xing; Ogas, Joe; Zhu, Jian-Kang; He, Xin-Jian; Zhang, Heng
in Arabidopsis thaliana. ...
... the diagnostic value of BRCA1/2  methylation 
BRCA promoter methylation in sporadic versus BRCA germline mutation-related breast cancers
BRCA promoter methylation in sporadic versus BRCA germline mutation-related breast cancers
Vos, Shoko; Moelans, Cathy Beatrice; van Diest, Paul Joannes
in distinguishing breast carcinomas of ...
... gene expression and morphology. DNA  methylation 
Epigenomic and functional analyses reveal roles of epialleles in the loss of photoperiod sensitivity during domestication of allotetraploid cottons
Epigenomic and functional analyses reveal roles of epialleles in the loss of photoperiod sensitivity during domestication of allotetraploid cottons
Song, Qingxin; Zhang, Tianzhen; Stelly, David M.; Chen, Z. Jeffrey
changes can produce meiotically stable ...
... Background DNA  methylation 
Widespread promoter methylation of synaptic plasticity genes in long-term potentiation in the adult brain in vivo
Widespread promoter methylation of synaptic plasticity genes in long-term potentiation in the adult brain in vivo
Maag, Jesper L. V.; Kaczorowski, Dominik C.; Panja, Debabrata; Peters, Timothy J.; Bramham, Clive R.; Wibrand, Karin; Dinger, Marcel E.
is a key modulator of gene expression in ...
... we investigated buccal cell DNA  methylation 
Physical activity, black carbon exposure, and DNA methylation in the FOXP3 promoter
Physical activity, black carbon exposure, and DNA methylation in the FOXP3 promoter
Lovinsky-Desir, Stephanie; Jung, Kyung Hwa; Jezioro, Jacqueline R.; Torrone, David Z.; de Planell-Saguer, Mariangels; Yan, Beizhan; Perera, Frederica P.; Rundle, Andrew G.; Perzanowski, Matthew S.; Chillrud, Steven N.; Miller, Rachel L.
of the forkhead box p3 (FOXP3) gene ...
... in histone modifications and DNA  methylation 
Comparative analysis of Histone modifications and DNA methylation at OsBZ8 locus under salinity stress in IR64 and Nonabokra rice varieties
Comparative analysis of Histone modifications and DNA methylation at OsBZ8 locus under salinity stress in IR64 and Nonabokra rice varieties
Paul, Amit; Dasgupta, Pratiti; Roy, Dipan; Chaudhuri, Shubho
at the locus between these varieties. ...
... of various subtypes by genome-wide DNA  methylation 
Genome-wide methylation profiles in primary intracranial germ cell tumors indicate a primordial germ cell origin for germinomas
Genome-wide methylation profiles in primary intracranial germ cell tumors indicate a primordial germ cell origin for germinomas
Fukushima, Shintaro; Yamashita, Satoshi; Kobayashi, Hisato; Takami, Hirokazu; Fukuoka, Kohei; Nakamura, Taishi; Yamasaki, Kai; Matsushita, Yuko; Nakamura, Hiromi; Totoki, Yasushi; Kato, Mamoru; Suzuki, Tomonari; Mishima, Kazuhiko; Yanagisawa, Takaaki; Mukasa, Akitake; Saito, Nobuhito; Kanamori, Masayuki; Kumabe, Toshihiro; Tominaga, Teiji; Nagane, Motoo; Iuchi, Toshihiko; Yoshimoto, Koji; Mizoguchi, Masahiro; Tamura, Kaoru; Sakai, Keiichi; Sugiyama, Kazuhiko; Nakada, Mitsutoshi; Yokogami, Kiyotaka; Takeshima, Hideo; Kanemura, Yonehiro; Matsuda, Masahide; Matsumura, Akira; Kurozumi, Kazuhiko; Ueki, Keisuke; Nonaka, Masahiro; Asai, Akio; Kawahara, Nobutaka; Hirose, Yuichi; Takayama, Tatusya; Nakazato, Yoichi; Narita, Yoshitaka; Shibata, Tatsuhiro; Matsutani, Masao; Ushijima, Toshikazu; Nishikawa, Ryo; Ichimura, Koichi; On behalf of The Intracranial Germ Cell Tumor Genome Analysis Consortium (The iGCTConsortium)
profiling. ...
... DNA  methylation 
The Role of DNA Methylation in Hypertension
The Role of DNA Methylation in Hypertension
Demura, Masashi; Saijoh, Kiyofumi
is the covalent modification of DNA that ...