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... Several studies have proved that DNA  methylation 
DNA methylation-based variation between human populations
DNA methylation-based variation between human populations
Kader, Farzeen; Ghai, Meenu
affects regulation of gene expression and ...
... Background Gene body  methylation 
Proximal methylation features associated with nonrandom changes in gene body methylation
Proximal methylation features associated with nonrandom changes in gene body methylation
Picard, Colette L.; Gehring, Mary
at CG dinucleotides is a widely conserved ...
... altering the genetic sequence itself. DNA  methylation 
The DNA Methylome: An Interface Between the Environment, Immunity, and Ageing
The DNA Methylome: An Interface Between the Environment, Immunity, and Ageing
McEwen, Lisa M.; Goodman, Sarah J.; Kobor, Michael S.; Jones, Meaghan J.
is arguably the most well-characterized ...
... rates of T2D and metabolic syndrome, with  methylation 
Tissue-specific methylation profile in obese patients with type 2 diabetes before and after Roux-en-Y gastric bypass
Tissue-specific methylation profile in obese patients with type 2 diabetes before and after Roux-en-Y gastric bypass
Sala, Priscila; Miranda Torrinhas, Raquel Susana Matos; Fonseca, Danielle Cristina; Ravacci, Graziela Rosa; Waitzberg, Dan Linetzky; Giannella-Neto, Daniel
profiles in promoter regions of genes in ...
... genetic changes to gene expression, DNA  methylation 
Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome
Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome
Cheung, Warren A.; Shao, Xiaojian; Morin, Andréanne; Siroux, Valérie; Kwan, Tony; Ge, Bing; Aïssi, Dylan; Chen, Lu; Vasquez, Louella; Allum, Fiona; Guénard, Frédéric; Bouzigon, Emmanuelle; Simon, Marie-Michelle; Boulier, Elodie; Redensek, Adriana; Watt, Stephen; Datta, Avik; Clarke, Laura; Flicek, Paul; Mead, Daniel; Paul, Dirk S.; Beck, Stephan; Bourque, Guillaume; Lathrop, Mark; Tchernof, André; Vohl, Marie-Claude; Demenais, Florence; Pin, Isabelle; Downes, Kate; Stunnenberg, Hendrick G.; Soranzo, Nicole; Pastinen, Tomi; Grundberg, Elin
, and histone marks but these ...
... Background DNA  methylation 
Single-base resolution methylomes of upland cotton (Gossypium hirsutum L.) reveal epigenome modifications in response to drought stress
Single-base resolution methylomes of upland cotton (Gossypium hirsutum L.) reveal epigenome modifications in response to drought stress
Lu, Xuke; Wang, Xiaoge; Chen, Xiugui; Shu, Na; Wang, Junjuan; Wang, Delong; Wang, Shuai; Fan, Weili; Guo, Lixue; Guo, Xiaoning; Ye, Wuwei
, with a cryptic role in genome ...
... global DNA hypomethylation. Aberrant DNA  methylation 
Hypermethylation of CDKN2A exon 2 in tumor, tumor-adjacent and tumor-distant tissues from breast cancer patients
Hypermethylation of CDKN2A exon 2 in tumor, tumor-adjacent and tumor-distant tissues from breast cancer patients
Spitzwieser, Melanie; Entfellner, Elisabeth; Werner, Bettina; Pulverer, Walter; Pfeiler, Georg; Hacker, Stefan; Cichna-Markl, Margit
levels have, however, not only been found ...
... Aberrant DNA  methylation 
Aberrant DNA methylation in melanoma: biomarker and therapeutic opportunities
Aberrant DNA methylation in melanoma: biomarker and therapeutic opportunities
Micevic, Goran; Theodosakis, Nicholas; Bosenberg, Marcus
is an epigenetic hallmark of melanoma, ...
... in CF-affected tissues and (ii) DNA  methylation 
DNA methylation at modifier genes of lung disease severity is altered in cystic fibrosis
DNA methylation at modifier genes of lung disease severity is altered in cystic fibrosis
Magalhães, Milena; Rivals, Isabelle; Claustres, Mireille; Varilh, Jessica; Thomasset, Mélodie; Bergougnoux, Anne; Mely, Laurent; Leroy, Sylvie; Corvol, Harriet; Guillot, Loïc; Murris, Marlène; Beyne, Emmanuelle; Caimmi, Davide; Vachier, Isabelle; Chiron, Raphaël; De Sario, Albertina
variations at disease modifier genes ...
... DNA methylationEpigenetic therapy DNA  methylation 
Epigenetic Basis of Human Cancer
Epigenetic Basis of Human Cancer
Mikeska, Thomas; Dobrovic, Alexander
, histone modificationsEpigenetic therapy ...
... DNA  methylation 
Tools and Strategies for Analysis of Genome-Wide and Gene-Specific DNA Methylation Patterns
Tools and Strategies for Analysis of Genome-Wide and Gene-Specific DNA Methylation Patterns
Chatterjee, Aniruddha; Rodger, Euan J.; Morison, Ian M.; Eccles, Michael R.; Stockwell, Peter A.
is a stable epigenetic mechanism that has ...
... Background DNA  methylation 
Widespread promoter methylation of synaptic plasticity genes in long-term potentiation in the adult brain in vivo
Widespread promoter methylation of synaptic plasticity genes in long-term potentiation in the adult brain in vivo
Maag, Jesper L. V.; Kaczorowski, Dominik C.; Panja, Debabrata; Peters, Timothy J.; Bramham, Clive R.; Wibrand, Karin; Dinger, Marcel E.
is a key modulator of gene expression in ...
... of various subtypes by genome-wide DNA  methylation 
Genome-wide methylation profiles in primary intracranial germ cell tumors indicate a primordial germ cell origin for germinomas
Genome-wide methylation profiles in primary intracranial germ cell tumors indicate a primordial germ cell origin for germinomas
Fukushima, Shintaro; Yamashita, Satoshi; Kobayashi, Hisato; Takami, Hirokazu; Fukuoka, Kohei; Nakamura, Taishi; Yamasaki, Kai; Matsushita, Yuko; Nakamura, Hiromi; Totoki, Yasushi; Kato, Mamoru; Suzuki, Tomonari; Mishima, Kazuhiko; Yanagisawa, Takaaki; Mukasa, Akitake; Saito, Nobuhito; Kanamori, Masayuki; Kumabe, Toshihiro; Tominaga, Teiji; Nagane, Motoo; Iuchi, Toshihiko; Yoshimoto, Koji; Mizoguchi, Masahiro; Tamura, Kaoru; Sakai, Keiichi; Sugiyama, Kazuhiko; Nakada, Mitsutoshi; Yokogami, Kiyotaka; Takeshima, Hideo; Kanemura, Yonehiro; Matsuda, Masahide; Matsumura, Akira; Kurozumi, Kazuhiko; Ueki, Keisuke; Nonaka, Masahiro; Asai, Akio; Kawahara, Nobutaka; Hirose, Yuichi; Takayama, Tatusya; Nakazato, Yoichi; Narita, Yoshitaka; Shibata, Tatsuhiro; Matsutani, Masao; Ushijima, Toshikazu; Nishikawa, Ryo; Ichimura, Koichi; On behalf of The Intracranial Germ Cell Tumor Genome Analysis Consortium (The iGCTConsortium)
profiling. ...
... folate, methionine) on infant DNA  methylation 
Maternal intake of methyl-group donors affects DNA methylation of metabolic genes in infants
Maternal intake of methyl-group donors affects DNA methylation of metabolic genes in infants
Pauwels, Sara; Ghosh, Manosij; Duca, Radu Corneliu; Bekaert, Bram; Freson, Kathleen; Huybrechts, Inge; Langie, Sabine A. S.; Koppen, Gudrun; Devlieger, Roland; Godderis, Lode
. ...
... Different studies validated that cytosine  methylation 
Epigenetics in Alzheimer’s Disease: Perspective of DNA Methylation
Epigenetics in Alzheimer’s Disease: Perspective of DNA Methylation
Qazi, Talal Jamil; Quan, Zhenzhen; Mir, Asif; Qing, Hong
of genomic DNA decreases with age in ...
... Background DNA  methylation 
Links between DNA methylation and nucleosome occupancy in the human genome
Links between DNA methylation and nucleosome occupancy in the human genome
Collings, Clayton K.; Anderson, John N.
is an epigenetic modification that is ...
... to mutation or, more commonly, due to DNA  methylation 
The dynamic DNA methylation landscape of the mutL homolog 1 shore is altered by MLH1-93G>A polymorphism in normal tissues and colorectal cancer
The dynamic DNA methylation landscape of the mutL homolog 1 shore is altered by MLH1-93G>A polymorphism in normal tissues and colorectal cancer
Savio, Andrea J.; Mrkonjic, Miralem; Lemire, Mathieu; Gallinger, Steven; Knight, Julia A.; Bapat, Bharat
of its promoter CpG island. ...
... Background To examine  methylation 
CpG Methylation across the adipogenic PPARγ gene and its relationship with birthweight and child BMI at 9 years
CpG Methylation across the adipogenic PPARγ gene and its relationship with birthweight and child BMI at 9 years
Volberg, Vitaly; Yousefi, Paul; Huen, Karen; Harley, Kim; Eskenazi, Brenda; Holland, Nina
of the peroxisome proliferator-activated ...
... in aging. Notably, age-associated DNA  methylation 
Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions
Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions
Cole, John J.; Robertson, Neil A.; Rather, Mohammed Iqbal; Thomson, John P.; McBryan, Tony; Sproul, Duncan; Wang, Tina; Brock, Claire; Clark, William; Ideker, Trey; Meehan, Richard R.; Miller, Richard A.; Brown-Borg, Holly M.; Adams, Peter D.
changes comprise a so-called aging ...
... Background DNA  methylation 
Pan-cancer analysis of frequent DNA co-methylation patterns reveals consistent epigenetic landscape changes in multiple cancers
Pan-cancer analysis of frequent DNA co-methylation patterns reveals consistent epigenetic landscape changes in multiple cancers
Zhang, Jie; Huang, Kun
is the major form of epigenetic ...
... two decades. In particular, aberrant DNA  methylation 
Mechanisms for the induction of gastric cancer by Helicobacter pylori infection: aberrant DNA methylation pathway
Mechanisms for the induction of gastric cancer by Helicobacter pylori infection: aberrant DNA methylation pathway
Maeda, Masahiro; Moro, Hiroshi; Ushijima, Toshikazu
is induced in multiple driver genes, ...
... in old age are poorly understood. DNA  methylation 
Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism
Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism
Hahn, Oliver; Grönke, Sebastian; Stubbs, Thomas M.; Ficz, Gabriella; Hendrich, Oliver; Krueger, Felix; Andrews, Simon; Zhang, Qifeng; Wakelam, Michael J.; Beyer, Andreas; Reik, Wolf; Partridge, Linda
could play an important role in mediating ...
... technological advances have enabled DNA  methylation 
DeepCpG: accurate prediction of single-cell DNA methylation states using deep learning
DeepCpG: accurate prediction of single-cell DNA methylation states using deep learning
Angermueller, Christof; Lee, Heather J.; Reik, Wolf; Stegle, Oliver
to be assayed at single-cell resolution. ...
... Background We present a new  methylation 
A relative quantitative Methylation-Sensitive Amplified Polymorphism (MSAP) method for the analysis of abiotic stress
A relative quantitative Methylation-Sensitive Amplified Polymorphism (MSAP) method for the analysis of abiotic stress
Bednarek, Piotr T.; Orłowska, Renata; Niedziela, Agnieszka
-sensitive amplified polymorphism (MSAP) ...
... Cigarette smoke (CS)-mediated DNA  methylation 
DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD
DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD
Sundar, Isaac K.; Yin, Qiangzong; Baier, Brian S.; Yan, Li; Mazur, Witold; Li, Dongmei; Susiarjo, Martha; Rahman, Irfan
can potentially affect several cellular ...