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... Several studies have proved that DNA  methylation 
DNA methylation-based variation between human populations
DNA methylation-based variation between human populations
Kader, Farzeen; Ghai, Meenu
affects regulation of gene expression and ...
... altering the genetic sequence itself. DNA  methylation 
The DNA Methylome: An Interface Between the Environment, Immunity, and Ageing
The DNA Methylome: An Interface Between the Environment, Immunity, and Ageing
McEwen, Lisa M.; Goodman, Sarah J.; Kobor, Michael S.; Jones, Meaghan J.
is arguably the most well-characterized ...
... rates of T2D and metabolic syndrome, with  methylation 
Tissue-specific methylation profile in obese patients with type 2 diabetes before and after Roux-en-Y gastric bypass
Tissue-specific methylation profile in obese patients with type 2 diabetes before and after Roux-en-Y gastric bypass
Sala, Priscila; Miranda Torrinhas, Raquel Susana Matos; Fonseca, Danielle Cristina; Ravacci, Graziela Rosa; Waitzberg, Dan Linetzky; Giannella-Neto, Daniel
profiles in promoter regions of genes in ...
... genetic changes to gene expression, DNA  methylation 
Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome
Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome
Cheung, Warren A.; Shao, Xiaojian; Morin, Andréanne; Siroux, Valérie; Kwan, Tony; Ge, Bing; Aïssi, Dylan; Chen, Lu; Vasquez, Louella; Allum, Fiona; Guénard, Frédéric; Bouzigon, Emmanuelle; Simon, Marie-Michelle; Boulier, Elodie; Redensek, Adriana; Watt, Stephen; Datta, Avik; Clarke, Laura; Flicek, Paul; Mead, Daniel; Paul, Dirk S.; Beck, Stephan; Bourque, Guillaume; Lathrop, Mark; Tchernof, André; Vohl, Marie-Claude; Demenais, Florence; Pin, Isabelle; Downes, Kate; Stunnenberg, Hendrick G.; Soranzo, Nicole; Pastinen, Tomi; Grundberg, Elin
, and histone marks but these ...
... in CF-affected tissues and (ii) DNA  methylation 
DNA methylation at modifier genes of lung disease severity is altered in cystic fibrosis
DNA methylation at modifier genes of lung disease severity is altered in cystic fibrosis
Magalhães, Milena; Rivals, Isabelle; Claustres, Mireille; Varilh, Jessica; Thomasset, Mélodie; Bergougnoux, Anne; Mely, Laurent; Leroy, Sylvie; Corvol, Harriet; Guillot, Loïc; Murris, Marlène; Beyne, Emmanuelle; Caimmi, Davide; Vachier, Isabelle; Chiron, Raphaël; De Sario, Albertina
variations at disease modifier genes ...
... DNA methylationEpigenetic therapy DNA  methylation 
Epigenetic Basis of Human Cancer
Epigenetic Basis of Human Cancer
Mikeska, Thomas; Dobrovic, Alexander
, histone modificationsEpigenetic therapy ...
... DNA  methylation 
Tools and Strategies for Analysis of Genome-Wide and Gene-Specific DNA Methylation Patterns
Tools and Strategies for Analysis of Genome-Wide and Gene-Specific DNA Methylation Patterns
Chatterjee, Aniruddha; Rodger, Euan J.; Morison, Ian M.; Eccles, Michael R.; Stockwell, Peter A.
is a stable epigenetic mechanism that has ...
... Background DNA  methylation 
Widespread promoter methylation of synaptic plasticity genes in long-term potentiation in the adult brain in vivo
Widespread promoter methylation of synaptic plasticity genes in long-term potentiation in the adult brain in vivo
Maag, Jesper L. V.; Kaczorowski, Dominik C.; Panja, Debabrata; Peters, Timothy J.; Bramham, Clive R.; Wibrand, Karin; Dinger, Marcel E.
is a key modulator of gene expression in ...
... of various subtypes by genome-wide DNA  methylation 
Genome-wide methylation profiles in primary intracranial germ cell tumors indicate a primordial germ cell origin for germinomas
Genome-wide methylation profiles in primary intracranial germ cell tumors indicate a primordial germ cell origin for germinomas
Fukushima, Shintaro; Yamashita, Satoshi; Kobayashi, Hisato; Takami, Hirokazu; Fukuoka, Kohei; Nakamura, Taishi; Yamasaki, Kai; Matsushita, Yuko; Nakamura, Hiromi; Totoki, Yasushi; Kato, Mamoru; Suzuki, Tomonari; Mishima, Kazuhiko; Yanagisawa, Takaaki; Mukasa, Akitake; Saito, Nobuhito; Kanamori, Masayuki; Kumabe, Toshihiro; Tominaga, Teiji; Nagane, Motoo; Iuchi, Toshihiko; Yoshimoto, Koji; Mizoguchi, Masahiro; Tamura, Kaoru; Sakai, Keiichi; Sugiyama, Kazuhiko; Nakada, Mitsutoshi; Yokogami, Kiyotaka; Takeshima, Hideo; Kanemura, Yonehiro; Matsuda, Masahide; Matsumura, Akira; Kurozumi, Kazuhiko; Ueki, Keisuke; Nonaka, Masahiro; Asai, Akio; Kawahara, Nobutaka; Hirose, Yuichi; Takayama, Tatusya; Nakazato, Yoichi; Narita, Yoshitaka; Shibata, Tatsuhiro; Matsutani, Masao; Ushijima, Toshikazu; Nishikawa, Ryo; Ichimura, Koichi; On behalf of The Intracranial Germ Cell Tumor Genome Analysis Consortium (The iGCTConsortium)
profiling. ...
... folate, methionine) on infant DNA  methylation 
Maternal intake of methyl-group donors affects DNA methylation of metabolic genes in infants
Maternal intake of methyl-group donors affects DNA methylation of metabolic genes in infants
Pauwels, Sara; Ghosh, Manosij; Duca, Radu Corneliu; Bekaert, Bram; Freson, Kathleen; Huybrechts, Inge; Langie, Sabine A. S.; Koppen, Gudrun; Devlieger, Roland; Godderis, Lode
. ...
... Different studies validated that cytosine  methylation 
Epigenetics in Alzheimer’s Disease: Perspective of DNA Methylation
Epigenetics in Alzheimer’s Disease: Perspective of DNA Methylation
Qazi, Talal Jamil; Quan, Zhenzhen; Mir, Asif; Qing, Hong
of genomic DNA decreases with age in ...
... to mutation or, more commonly, due to DNA  methylation 
The dynamic DNA methylation landscape of the mutL homolog 1 shore is altered by MLH1-93G>A polymorphism in normal tissues and colorectal cancer
The dynamic DNA methylation landscape of the mutL homolog 1 shore is altered by MLH1-93G>A polymorphism in normal tissues and colorectal cancer
Savio, Andrea J.; Mrkonjic, Miralem; Lemire, Mathieu; Gallinger, Steven; Knight, Julia A.; Bapat, Bharat
of its promoter CpG island. ...
... Background To examine  methylation 
CpG Methylation across the adipogenic PPARγ gene and its relationship with birthweight and child BMI at 9 years
CpG Methylation across the adipogenic PPARγ gene and its relationship with birthweight and child BMI at 9 years
Volberg, Vitaly; Yousefi, Paul; Huen, Karen; Harley, Kim; Eskenazi, Brenda; Holland, Nina
of the peroxisome proliferator-activated ...
... Background DNA  methylation 
Pan-cancer analysis of frequent DNA co-methylation patterns reveals consistent epigenetic landscape changes in multiple cancers
Pan-cancer analysis of frequent DNA co-methylation patterns reveals consistent epigenetic landscape changes in multiple cancers
Zhang, Jie; Huang, Kun
is the major form of epigenetic ...
... two decades. In particular, aberrant DNA  methylation 
Mechanisms for the induction of gastric cancer by Helicobacter pylori infection: aberrant DNA methylation pathway
Mechanisms for the induction of gastric cancer by Helicobacter pylori infection: aberrant DNA methylation pathway
Maeda, Masahiro; Moro, Hiroshi; Ushijima, Toshikazu
is induced in multiple driver genes, ...
... in technology, changes in DNA  methylation 
Analysis of the interplay between methylation and expression reveals its potential role in cancer aetiology
Analysis of the interplay between methylation and expression reveals its potential role in cancer aetiology
Ozer, Bugra; Sezerman, Ugur
levels have become prevalent to study ...
... DNA  methylation 
Analysis of Global Genome Methylation Using the Cytosine-Extension Assay
Analysis of Global Genome Methylation Using the Cytosine-Extension Assay
Bilichak, Andriy; Kovalchuk, Igor
is a reversible covalent chemical ...
... abnormalities. Recent genome-wide DNA  methylation 
Clinical implications of genome-wide DNA methylation studies in acute myeloid leukemia
Clinical implications of genome-wide DNA methylation studies in acute myeloid leukemia
Li, Yan; Xu, Qingyu; Lv, Na; Wang, Lili; Zhao, Hongmei; Wang, Xiuli; Guo, Jing; Chen, Chongjian; Li, Yonghui; Yu, Li
studies have highlighted an important ...
... However, the combined genome-wide DNA  methylation 
Abnormal epigenetic changes during differentiation of human skeletal muscle stem cells from obese subjects
Abnormal epigenetic changes during differentiation of human skeletal muscle stem cells from obese subjects
Davegårdh, Cajsa; Broholm, Christa; Perfilyev, Alexander; Henriksen, Tora; García-Calzón, Sonia; Peijs, Lone; Hansen, Ninna Schiøler; Volkov, Petr; Kjøbsted, Rasmus; Wojtaszewski, Jørgen F. P.; Pedersen, Maria; Pedersen, Bente Klarlund; Ballak, Dov B.; Dinarello, Charles A.; Heinhuis, Bas; Joosten, Leo A. B.; Nilsson, Emma; Vaag, Allan; Scheele, Camilla; Ling, Charlotte
and expression changes taking place ...
... Background Variation in DNA  methylation 
Inter-individual variation in DNA methylation is largely restricted to tissue-specific differentially methylated regions in maize
Inter-individual variation in DNA methylation is largely restricted to tissue-specific differentially methylated regions in maize
Lauria, Massimiliano; Echegoyen-Nava, Rodrigo Antonio; Rodríguez-Ríos, Dalia; Zaina, Silvio; Lund, Gertrud
across distinct genetic populations, or ...
... Purpose DNA  methylation 
Methylation analysis in fatty-acid-related genes reveals their plasticity associated with conjugated linoleic acid and calcium supplementation in adult mice
Methylation analysis in fatty-acid-related genes reveals their plasticity associated with conjugated linoleic acid and calcium supplementation in adult mice
Chaplin, Alice; Palou, Andreu; Serra, Francisca
is one of the most extensively studied ...
... study was to investigate the promoter  methylation 
Aberrant methylation of DACT1 and DACT2 are associated with tumor progression and poor prognosis in esophageal squamous cell carcinoma
Aberrant methylation of DACT1 and DACT2 are associated with tumor progression and poor prognosis in esophageal squamous cell carcinoma
Guo, Yan-li; Shan, Bao-En; Guo, Wei; Dong, Zhi-Ming; Zhou, Zhen; Shen, Su-Peng; Guo, Xin; Liang, Jia; Kuang, Gang
and expression of DACT family, in order ...
... are important resources for profiling DNA  methylation 
Improved results of LINE-1 methylation analysis in formalin-fixed, paraffin-embedded tissues with the application of a heating step during the DNA extraction process
Improved results of LINE-1 methylation analysis in formalin-fixed, paraffin-embedded tissues with the application of a heating step during the DNA extraction process
Wen, Xianyu; Jeong, Seorin; Kim, Younghoon; Bae, Jeong Mo; Cho, Nam Yun; Kim, Jung Ho; Kang, Gyeong Hoon
changes and for studying a variety of ...
... (GC) is highly influenced by aberrant  methylation 
Epigenetic inactivation of FAT4 contributes to gastric field cancerization
Epigenetic inactivation of FAT4 contributes to gastric field cancerization
Yoshida, Satoshi; Yamashita, Satoshi; Niwa, Tohru; Mori, Akiko; Ito, Seiji; Ichinose, Masao; Ushijima, Toshikazu
, and accumulation of aberrant ...
... between epigenetics, especially DNA  methylation 
DNA methylation patterns of behavior-related gene promoter regions dissect the gray wolf from domestic dog breeds
DNA methylation patterns of behavior-related gene promoter regions dissect the gray wolf from domestic dog breeds
Banlaki, Zsofia; Cimarelli, Giulia; Viranyi, Zsofia; Kubinyi, Eniko; Sasvari-Szekely, Maria; Ronai, Zsolt
, and population divergence as well as ...