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... In the mouse, the patterns of DNA  methylation 
Ontogeny of CpG island methylation and specificity of DNMT3 methyltransferases during embryonic development in the mouse
Ontogeny of CpG island methylation and specificity of DNMT3 methyltransferases during embryonic development in the mouse
Auclair, Ghislain; Guibert, Sylvain; Bender, Ambre; Weber, Michael
are established during early embryonic ...
... with a particular focus on DNA  methylation 
One-Carbon Metabolism Nutrients and Epigenetics: A Mechanistic Link Between Aberrant One-Carbon Metabolism and Cancer Risk?
One-Carbon Metabolism Nutrients and Epigenetics: A Mechanistic Link Between Aberrant One-Carbon Metabolism and Cancer Risk?
Masih, Shannon; Plumptre, Lesley A.; Kim, Young-In
. ...
... the impact of sex on the genome-wide DNA  methylation 
Sex differences in the genome-wide DNA methylation pattern and impact on gene expression, microRNA levels and insulin secretion in human pancreatic islets
Sex differences in the genome-wide DNA methylation pattern and impact on gene expression, microRNA levels and insulin secretion in human pancreatic islets
Hall, Elin; Volkov, Petr; Dayeh, Tasnim; Esguerra, Jonathan Lou S; Salö, Sofia; Eliasson, Lena; Rönn, Tina; Bacos, Karl; Ling, Charlotte
pattern in human pancreatic islets from ...
... Background DNA  methylation 
Whole-genome bisulfite sequencing of multiple individuals reveals complementary roles of promoter and gene body methylation in transcriptional regulation
Whole-genome bisulfite sequencing of multiple individuals reveals complementary roles of promoter and gene body methylation in transcriptional regulation
Lou, Shaoke; Lee, Heung-Man; Qin, Hao; Li, Jing-Woei; Gao, Zhibo; Liu, Xin; Chan, Landon L; KL Lam, Vincent; So, Wing-Yee; Wang, Ying; Lok, Si; Wang, Jun; Ma, Ronald CW; Tsui, Stephen Kwok-Wing; Chan, Juliana CN; Chan, Ting-Fung; Yip, Kevin Y
is an important type of epigenetic ...
... the effects of 5-azacytidine on DNA  methylation 
DNMT inhibitors reverse a specific signature of aberrant promoter DNA methylation and associated gene silencing in AML
DNMT inhibitors reverse a specific signature of aberrant promoter DNA methylation and associated gene silencing in AML
Lund, Kirstin; Cole, John J; VanderKraats, Nathan D; McBryan, Tony; Pchelintsev, Nikolay A; Clark, William; Copland, Mhairi; Edwards, John R; Adams, Peter D
and gene expression using whole-genome ...
... neck squamous cell carcinomas (HNSCC).  Methylation 
Quantitative methodology is critical for assessing DNA methylation and impacts on correlation with patient outcome
Quantitative methodology is critical for assessing DNA methylation and impacts on correlation with patient outcome
Lim, Annette M; Candiloro, Ida LM; Wong, Nicholas; Collins, Marnie; Do, Hongdo; Takano, Elena A; Angel, Christopher; Young, Richard J; Corry, June; Wiesenfeld, David; Kleid, Stephen; Sigston, Elizabeth; Lyons, Bernard; Rischin, Danny; Solomon, Benjamin; Dobrovic, Alexander
has been commonly assessed with ...
... truffle Tuber melanosporum exploits DNA  methylation 
Non-exhaustive DNA methylation-mediated transposon silencing in the black truffle genome, a complex fungal genome with massive repeat element content
Non-exhaustive DNA methylation-mediated transposon silencing in the black truffle genome, a complex fungal genome with massive repeat element content
Montanini, Barbara; Chen, Pao-Yang; Morselli, Marco; Jaroszewicz, Artur; Lopez, David; Martin, Francis; Ottonello, Simone; Pellegrini, Matteo
to cope with the more than 45,000 ...
... The comparison of DNA  methylation 
Pan-cancer patterns of DNA methylation
Pan-cancer patterns of DNA methylation
Witte, Tania; Plass, Christoph; Gerhauser, Clarissa
patterns across cancer types (pan-cancer ...
... genome-wide studies found that DNA  methylation 
Whole DNA methylome profiling in lung cancer cells before and after epithelial-to-mesenchymal transition
Whole DNA methylome profiling in lung cancer cells before and after epithelial-to-mesenchymal transition
Liu, Fatao; Zhou, Yi; Zhou, Daizhan; Kan, Mengyuan; Niu, Xiaomin; Zhang, Zhou; Zhang, Di; Tao, Liming; He, Lin; Zhan, Lixing; Liu, Yun
was unchanged during EMT induced by TGF-β ...
... potential for the development of new DNA  methylation 
A panel of genes methylated with high frequency in colorectal cancer
A panel of genes methylated with high frequency in colorectal cancer
Mitchell, Susan M; Ross, Jason P; Drew, Horace R; Ho, Thu; Brown, Glenn S; Saunders, Neil FW; Duesing, Konsta R; Buckley, Michael J; Dunne, Rob; Beetson, Iain; Rand, Keith N; McEvoy, Aidan; Thomas, Melissa L; Baker, Rohan T; Wattchow, David A; Young, Graeme P; Lockett, Trevor J; Pedersen, Susanne K; LaPointe, Lawrence C; Molloy, Peter L
biomarkers or panels to improve the ...
... and persistence of sex differences in DNA  methylation 
The effects of perinatal testosterone exposure on the DNA methylome of the mouse brain are late-emerging
The effects of perinatal testosterone exposure on the DNA methylome of the mouse brain are late-emerging
Ghahramani, Negar M; Ngun, Tuck C; Chen, Pao-Yang; Tian, Yuan; Krishnan, Sangitha; Muir, Stephanie; Rubbi, Liudmilla; Arnold, Arthur P; de Vries, Geert J; Forger, Nancy G; Pellegrini, Matteo; Vilain, Eric
, we performed genome-wide surveys in ...
... Background DNA  methylation 
The relationship between DNA methylation, genetic and expression inter-individual variation in untransformed human fibroblasts
The relationship between DNA methylation, genetic and expression inter-individual variation in untransformed human fibroblasts
Wagner, James R; Busche, Stephan; Ge, Bing; Kwan, Tony; Pastinen, Tomi; Blanchette, Mathieu
plays an essential role in the regulation ...
... instable iPSCs with aberrant DNA  methylation 
Deciphering the heterogeneity in DNA methylation patterns during stem cell differentiation and reprogramming
Deciphering the heterogeneity in DNA methylation patterns during stem cell differentiation and reprogramming
Shao, Xiaojian; Zhang, Cuiyun; Sun, Ming-An; Lu, Xuemei; Xie, Hehuang
may divide and differentiate into cancer ...
... that form the foundation of the histone  methylation 
Histone Methylation in Chromatin Signaling
Histone Methylation in Chromatin Signaling
Gozani, Or; Shi, Yang
field. ...
... microarrays to compare genomewide  methylation 
Identification and characterization of locus-specific methylation patterns within novel loci undergoing hypermethylation during breast cancer pathogenesis
Identification and characterization of locus-specific methylation patterns within novel loci undergoing hypermethylation during breast cancer pathogenesis
Wojdacz, Tomasz K; Windeløv, Johanne A; Thestrup, Britta B; Damsgaard, Tine E; Overgaard, Jens; Hansen, Lise Lotte
patterns of breast carcinomas (n = 20) ...
... Differential distribution of DNA  methylation 
Analysis of DNA methylation acquisition at the imprinted Dlk1 locus reveals asymmetry at CpG dyads
Analysis of DNA methylation acquisition at the imprinted Dlk1 locus reveals asymmetry at CpG dyads
Gagne, Alyssa; Hochman, Abigail; Qureshi, Mahvish; Tong, Celia; Arbon, Jessica; McDaniel, Kayla; Davis, Tamara L
on the parental alleles of imprinted ...
... Background  Methylation 
Haplotype defined by the MLH1-93G/A polymorphism is associated with MLH1 promoter hypermethylation in sporadic colorectal cancers
Haplotype defined by the MLH1-93G/A polymorphism is associated with MLH1 promoter hypermethylation in sporadic colorectal cancers
Miyakura, Yasuyuki; Tahara, Makiko; Lefor, Alan T; Yasuda, Yoshikazu; Sugano, Kokichi
of the MLH1 promoter region has been ...
... will be increasingly important. DNA  methylation 
Acquisition of aberrant DNA methylation is associated with frailty in the very old: findings from the Newcastle 85+ Study
Acquisition of aberrant DNA methylation is associated with frailty in the very old: findings from the Newcastle 85+ Study
Collerton, Joanna; Gautrey, Hannah E.; Otterdijk, Sanne D.; Davies, Karen; Martin-Ruiz, Carmen; Zglinicki, Thomas; Kirkwood, Thomas B. L.; Jagger, Carol; Mathers, John C.; Strathdee, Gordon
patterns within genomic DNA change during ...
... C-5 DNA  methylation 
A single CMT methyltransferase homolog is involved in CHG DNA methylation and development of Physcomitrella patens
A single CMT methyltransferase homolog is involved in CHG DNA methylation and development of Physcomitrella patens
Noy-Malka, Chen; Yaari, Rafael; Itzhaki, Rachel; Mosquna, Assaf; Auerbach Gershovitz, Nitzan; Katz, Aviva; Ohad, Nir
is an essential mechanism controlling ...
... involves epigenetic remodeling. DNA  methylation 
Aberrant DNA methylation reprogramming during induced pluripotent stem cell generation is dependent on the choice of reprogramming factors
Aberrant DNA methylation reprogramming during induced pluripotent stem cell generation is dependent on the choice of reprogramming factors
Planello, Aline C; Ji, Junfeng; Sharma, Vivek; Singhania, Rajat; Mbabaali, Faridah; Müller, Fabian; Alfaro, Javier A; Bock, Christoph; De Carvalho, Daniel D; Batada, Nizar N
at a significant proportion of CpG sites ...
... and divergent characteristics of DNA  methylation 
Genome-wide and single-base resolution DNA methylomes of the Pacific oyster Crassostrea gigas provide insight into the evolution of invertebrate CpG methylation
Genome-wide and single-base resolution DNA methylomes of the Pacific oyster Crassostrea gigas provide insight into the evolution of invertebrate CpG methylation
Wang, Xiaotong; Li, Qiye; Lian, Jinmin; Li, Li; Jin, Lijun; Cai, Huimin; Xu, Fei; Qi, Haigang; Zhang, Linlin; Wu, Fucun; Meng, Jie; Que, Huayong; Fang, Xiaodong; Guo, Ximing; Zhang, Guofan
among phylogenetic groups. ...
... DNA  methylation 
Characteristics of cytosine methylation status and methyltransferase genes in the early development stage of cauliflower (Brassica oleracea L. var. botrytis)
Characteristics of cytosine methylation status and methyltransferase genes in the early development stage of cauliflower (Brassica oleracea L. var. botrytis)
Li, Hui; Geng, Meijuan; Liu, Qian; Jin, Chuan; Zhang, Qingli; Chen, Chengbin; Song, Wenqin; Wang, Chunguo
is one of the most important epigenetic ...
... of invasive breast carcinoma. DNA  methylation 
Genome-wide DNA methylation profiles in progression to in situand invasive carcinoma of the breast with impact on gene transcription and prognosis
Genome-wide DNA methylation profiles in progression to in situand invasive carcinoma of the breast with impact on gene transcription and prognosis
Fleischer, Thomas; Frigessi, Arnoldo; Johnson, Kevin C; Edvardsen, Hege; Touleimat, Nizar; Klajic, Jovana; Riis, Margit LH; Haakensen, Vilde D; Wärnberg, Fredrik; Naume, Bjørn; Helland, Åslaug; Børresen-Dale, Anne-Lise; Tost, Jörg; Christensen, Brock C; Kristensen, Vessela N
alterations are thought to be an early ...
... Background The  methylation 
Gene expression and nucleotide composition are associated with genic methylation level in Oryza sativa
Gene expression and nucleotide composition are associated with genic methylation level in Oryza sativa
Elhaik, Eran; Pellegrini, Matteo; Tatarinova, Tatiana V
of cytosines at CpG dinucleotides, which ...
... that the GDF5 locus is subject to DNA  methylation 
CpG methylation regulates allelic expression of GDF5 by modulating binding of SP1 and SP3 repressor proteins to the osteoarthritis susceptibility SNP rs143383
CpG methylation regulates allelic expression of GDF5 by modulating binding of SP1 and SP3 repressor proteins to the osteoarthritis susceptibility SNP rs143383
Reynard, Louise N.; Bui, Catherine; Syddall, Catherine M.; Loughlin, John
and that allelic imbalance of rs143383 is ...