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... Background DNA  methylation 
DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines
DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines
Bell, Jordana T; Pai, Athma A; Pickrell, Joseph K; Gaffney, Daniel J; Pique-Regi, Roger; Degner, Jacob F; Gilad, Yoav; Pritchard, Jonathan K
is an essential epigenetic mechanism ...
... (DMR) which has allele specific DNA  methylation 
Quantitative analysis of DNA methylation at all human imprinted regions reveals preservation of epigenetic stability in adult somatic tissue
Quantitative analysis of DNA methylation at all human imprinted regions reveals preservation of epigenetic stability in adult somatic tissue
Woodfine, Kathryn; Huddleston, Joanna E; Murrell, Adele
and contributes to imprinted gene ...
... Background Changes in DNA  methylation 
Genome-wide survey reveals dynamic widespread tissue-specific changes in DNA methylation during development
Genome-wide survey reveals dynamic widespread tissue-specific changes in DNA methylation during development
Liang, Ping; Song, Fei; Ghosh, Srimoyee; Morien, Evan; Qin, Maochun; Mahmood, Saleh; Fujiwara, Kyoko; Igarashi, Jun; Nagase, Hiroki; Held, William A
in the mammalian genome during ...
... analysis of the genome-wide DNA  methylation 
A comparative analysis of DNA methylation across human embryonic stem cell lines
A comparative analysis of DNA methylation across human embryonic stem cell lines
Chen, Pao-Yang; Feng, Suhua; Joo, Jong Wha Joanne; Jacobsen, Steve E; Pellegrini, Matteo
profiles from three human embryonic stem ...
... our own, have proposed the use of DNA  methylation 
An integrative analysis of DNA methylation and RNA-Seq data for human heart, kidney and liver
An integrative analysis of DNA methylation and RNA-Seq data for human heart, kidney and liver
Xie, Linglin; Weichel, Brent; Ohm, Joyce Ellen; Zhang, Ke
profiles as biomarkers for various ...
... epigenetic modifications including DNA  methylation 
Chromosome-wide DNA methylation analysis predicts human tissue-specific X inactivation
Chromosome-wide DNA methylation analysis predicts human tissue-specific X inactivation
Cotton, Allison M.; Lam, Lucia; Affleck, Joslynn G.; Wilson, Ian M.; Peñaherrera, Maria S.; McFadden, Deborah E.; Kobor, Michael S.; Lam, Wan L.; Robinson, Wendy P.; Brown, Carolyn J.
. ...
... et al. 2009; Cui et al. 2010). DNA  methylation 
Epigenetics and its implications for ecotoxicology
Epigenetics and its implications for ecotoxicology
Vandegehuchte, Michiel B.; Janssen, Colin R.
DNA ...
... data support the hypothesis that DNA  methylation 
DNA methylation, the early-life social environment and behavioral disorders
DNA methylation, the early-life social environment and behavioral disorders
Szyf, Moshe
, a covalent modification of the DNA ...
... DMRs. Results By comparing the promoter  methylation 
Genome-wide mapping of imprinted differentially methylated regions by DNA methylation profiling of human placentas from triploidies
Genome-wide mapping of imprinted differentially methylated regions by DNA methylation profiling of human placentas from triploidies
Yuen, Ryan KC; Jiang, Ruby; Peñaherrera, Maria S; McFadden, Deborah E; Robinson, Wendy P
status of over 14,000 genes in human ...
... and neck carcinogenesis. In cancer, DNA  methylation 
Role of DNA methylation in head and neck cancer
Role of DNA methylation in head and neck cancer
Demokan, Semra; Dalay, Nejat
patterns display specific aberrations ...
... shared gene expression and a lack of  methylation 
Variable methylation of the imprinted gene, SNRPN, supports a relationship between intracranial germ cell tumours and neural stem cells
Variable methylation of the imprinted gene, SNRPN, supports a relationship between intracranial germ cell tumours and neural stem cells
Lee, Shih-Han; Appleby, Vanessa; Jeyapalan, Jennie N.; Palmer, Roger D.; Nicholson, James C.; Sottile, Virginie; Gao, Erning; Coleman, Nicholas; Scotting, Paul J.
of imprinted genes, including SNRPN. ...
... Background DNA  methylation 
Functional complementation between transcriptional methylation regulation and post-transcriptional microRNA regulation in the human genome
Functional complementation between transcriptional methylation regulation and post-transcriptional microRNA regulation in the human genome
Su, Zhixi; Xia, Junfeng; Zhao, Zhongming
in the 5' promoter regions of genes and ...
... study was to investigate MGMT promoter  methylation 
MGMT promoter methylation and immunoexpression in aggressive pituitary adenomas and carcinomas
MGMT promoter methylation and immunoexpression in aggressive pituitary adenomas and carcinomas
Salehi, Fateme; Scheithauer, Bernd W.; Kros, Johann M.; Lau, Queenie; Fealey, Michael; Erickson, Dana; Kovacs, Kalman; Horvath, Eva; Lloyd, Ricardo V.
and immunoexpression in an aggressive ...
... Background The  methylation 
A refined, rapid and reproducible high resolution melt (HRM)-based method suitable for quantification of global LINE-1 repetitive element methylation
A refined, rapid and reproducible high resolution melt (HRM)-based method suitable for quantification of global LINE-1 repetitive element methylation
Tse, M Yat; Ashbury, Janet E; Zwingerman, Nora; King, Will D; Taylor, Sherry AM; Pang, Stephen C
of DNA is recognized as a key mechanism ...
... We performed MethyLight analysis for the  methylation 
Promoter CpG island hypermethylation during breast cancer progression
Promoter CpG island hypermethylation during breast cancer progression
Park, So Yeon; Kwon, Hyeong Ju; Lee, Hee Eun; Ryu, Han Suk; Kim, Sung-Won; Kim, Jee Hyun; Kim, In Ah; Jung, Namhee; Cho, Nam-Yun; Kang, Gyeong Hoon
status of 57 promoter CpG island loci in ...
... by epigenetic regulation, including DNA  methylation 
Extensive epigenetic reprogramming in human somatic tissues between fetus and adult
Extensive epigenetic reprogramming in human somatic tissues between fetus and adult
Yuen, Ryan KC; Neumann, Sarah MA; Fok, Alexandra K; Peñaherrera, Maria S; McFadden, Deborah E; Robinson, Wendy P; Kobor, Michael S
. ...
... Background DNA  methylation 
DNA Methylation in the Rectal Mucosa Is Associated with Crypt Proliferation and Fecal Short-Chain Fatty Acids
DNA Methylation in the Rectal Mucosa Is Associated with Crypt Proliferation and Fecal Short-Chain Fatty Acids
Worthley, Daniel L.; Whitehall, Vicki L. J.; Leu, Richard K.; Irahara, Natsumi; Buttenshaw, Ronald L.; Mallitt, Kylie-Ann; Greco, Sonia A.; Ramsnes, Ingunn; Winter, Jean; Hu, Ying; Ogino, Shuji; Young, Graeme P.; Leggett, Barbara A.
varies throughout the normal colorectal ...
... EFS (embryonal Fyn-associated substrate)  methylation 
EFS shows biallelic methylation in uveal melanoma with poor prognosis as well as tissue-specific methylation
EFS shows biallelic methylation in uveal melanoma with poor prognosis as well as tissue-specific methylation
Neumann, Lisa C; Weinhäusel, Andreas; Thomas, Stefanie; Horsthemke, Bernhard; Lohmann, Dietmar R; Zeschnigk, Michael
analyses in UM, cultured uveal ...
... study, we performed a genome-wide DNA  methylation 
Evidence for widespread changes in promoter methylation profile in human placenta in response to increasing gestational age and environmental/stochastic factors
Evidence for widespread changes in promoter methylation profile in human placenta in response to increasing gestational age and environmental/stochastic factors
Novakovic, Boris; Yuen, Ryan K; Gordon, Lavinia; Penaherrera, Maria S; Sharkey, Andrew; Moffett, Ashley; Craig, Jeffrey M; Robinson, Wendy P; Saffery, Richard
analysis of gene promoters in placenta ...
... Background RASSF1A gene silencing by DNA  methylation 
Methylation-associated down-regulation of RASSF1A and up-regulation of RASSF1Cin pancreatic endocrine tumors
Methylation-associated down-regulation of RASSF1A and up-regulation of RASSF1Cin pancreatic endocrine tumors
Malpeli, Giorgio; Amato, Eliana; Dandrea, Mario; Fumagalli, Caterina; Debattisti, Valentina; Boninsegna, Letizia; Pelosi, Giuseppe; Falconi, Massimo; Scarpa, Aldo
has been suggested as a major event in ...
... Background Changes in DNA  methylation 
Parental ages and levels of DNA methylation in the newborn are correlated
Parental ages and levels of DNA methylation in the newborn are correlated
Adkins, Ronald M; Thomas, Fridtjof; Tylavsky, Frances A; Krushkal, Julia
patterns with age frequently have been ...
... in bladder cancer; however the DNA  methylation 
Distinct DNA methylation epigenotypes in bladder cancer from different Chinese sub-populations and its implication in cancer detection using voided urine
Distinct DNA methylation epigenotypes in bladder cancer from different Chinese sub-populations and its implication in cancer detection using voided urine
Chen, Pi-Che; Tsai, Ming-Hsuan; Yip, Sidney KH; Jou, Yeong-Chin; Ng, Chi-Fai; Chen, Yanning; Wang, Xiaoling; Huang, Wei; Tung, Chun-Liang; Chen, Gary CW; Huang, Martin MS; Tong, Joanna HM; Song, Eing-Ju; Chang, De-Ching; Hsu, Cheng-Da; To, Ka-Fai; Shen, Cheng-Huang; Chan, Michael WY
profile of bladder cancer in Taiwan is ...
... Background DNA  methylation 
Chromosome-wide mapping of DNA methylation patterns in normal and malignant prostate cells reveals pervasive methylation of gene-associated and conserved intergenic sequences
Chromosome-wide mapping of DNA methylation patterns in normal and malignant prostate cells reveals pervasive methylation of gene-associated and conserved intergenic sequences
Yegnasubramanian, Srinivasan; Wu, Zhijin; Haffner, Michael C; Esopi, David; Aryee, Martin J; Badrinath, Raghav; He, Tony L; Morgan, James D; Carvalho, Benilton; Zheng, Qizhi; De Marzo, Angelo M; Irizarry, Rafael A; Nelson, William G
has been linked to genome regulation and ...
... in mammalian chromatin, the 5′-  methylation 
DNA Repair and the Control of DNA Methylation
DNA Repair and the Control of DNA Methylation
Schär, Primo; Fritsch, Olivier
of cytosine in CpG dinucleotides is ...
... by a variety of molecular mechanisms: DNA  methylation 
Techniques to Study DNA Methylation and Histone Modification
Techniques to Study DNA Methylation and Histone Modification
Lara, Ester; Calvanese, Vincenzo; Fernandez, Agustin F.; Fraga, Mario F.
, post-translational histone ...