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... hope for improved therapy. Aberrant  methylation 
Frequent but borderline methylation of p16INK4a and TIMP3 in medulloblastoma and sPNET revealed by quantitative analyses
Frequent but borderline methylation of p16INK4a and TIMP3 in medulloblastoma and sPNET revealed by quantitative analyses
Mühlisch, J.; Bajanowski, T.; Rickert, C. H.; Roggendorf, W.; Würthwein, G.; Jürgens, H.; Frühwald, M. C.
is common in malignant brain tumors of ...
... has been shown to occur in cancer; DNA  methylation 
IGF-II promoter methylation and ovarian cancer prognosis
IGF-II promoter methylation and ovarian cancer prognosis
Beeghly, A. C.; Katsaros, D.; Wiley, A. L.; Rigault de la Longrais, I. A.; Prescott, A. T.; Chen, H.; Puopolo, M.; Rutherford, T. J.; Yu, H.
regulates promoter use. ...
... histone modifications and DNA  methylation 
Involvement of DNA methylation in tree development and micropropagation
Involvement of DNA methylation in tree development and micropropagation
Valledor, Luis; Hasbún, Rodrigo; Meijón, Mónica; Rodríguez, Jose Luis; Santamaría, Estrella; Viejo, Marcos; Berdasco, Maria; Feito, Isabel; Fraga, Mario F.; Cañal, Maria Jesús; Rodríguez, Roberto
are some of the epigenetic mechanisms ...
... dynamics and inheritance of DNA  methylation 
Endosperm-specific hypomethylation, and meiotic inheritance and variation of DNA methylation level and pattern in sorghum (Sorghum bicolor L.) inter-strain hybrids
Endosperm-specific hypomethylation, and meiotic inheritance and variation of DNA methylation level and pattern in sorghum (Sorghum bicolor L.) inter-strain hybrids
Zhang, M. S.; Yan, H. Y.; Zhao, N.; Lin, X. Y.; Pang, J. S.; Xu, K. Z.; Liu, L. X.; Liu, B.
represents important facets for ...
... activity, contributes to DNA  methylation 
Loss of spermatogonia and wide-spread DNA methylation defects in newborn male mice deficient in DNMT3L
Loss of spermatogonia and wide-spread DNA methylation defects in newborn male mice deficient in DNMT3L
La Salle, Sophie; Oakes, Christopher C; Neaga, Oana R; Bourc'his, Déborah; Bestor, Timothy H; Trasler, Jacquetta M
pattern acquisition during gametogenesis ...
... Methods Age-related increases in DNA  methylation 
Lack of increases in methylation at three CpG-rich genomic loci in non-mitotic adult tissues during aging
Lack of increases in methylation at three CpG-rich genomic loci in non-mitotic adult tissues during aging
Chu, Michelle W; Siegmund, Kimberly D; Eckstam, Carrie L; Kim, Jung Yeon; Yang, Allen S; Kanel, Gary C; Tavaré, Simon; Shibata, Darryl
at specific CpG sites (termed "epigenetic ...
... Introduction Aberrant DNA  methylation 
Correlation between CpG methylation profiles and hormone receptor status in breast cancers
Correlation between CpG methylation profiles and hormone receptor status in breast cancers
Feng, Weiwei; Shen, Lanlan; Wen, Sijin; Rosen, Daniel G; Jelinek, Jaroslav; Hu, Xin; Huan, Shaoyi; Huang, Miao; Liu, Jinsong; Sahin, Aysegul A; Hunt, Kelly K; Bast, Robert C, Jr; Shen, Yu; Issa, Jean-Pierre J; Yu, Yinhua
has been found frequently in human breast ...
... DNA  methylation 
First evidence of methylation in the genome of Drosophila willistoni
First evidence of methylation in the genome of Drosophila willistoni
Garcia, Rosane Nunes; D’Ávila, Marícia Fantinel; Robe, Lizandra Jaqueline; Loreto, Elgion Lúcio da Silva; Panzera, Yanina; Heredia, Fabiana Oliveira; Valente, Vera Lúcia da Silva
has been studied abundantly in ...
... of the offspring. Differences in the DNA  methylation 
Maternal Programming of Glucocorticoid Receptor Expression and HPA Responses to Stress Through DNA Methylation in the Rat
Maternal Programming of Glucocorticoid Receptor Expression and HPA Responses to Stress Through DNA Methylation in the Rat
Meaney, M. J.; Weaver, I. C. G.; Wu, T.; Hellstrom, I.; Diorio, J.; Szyf, Moshe
pattern between the offspring of high- ...
... of this study were (a) to compare the  methylation 
Methylation profile in benign, borderline and malignant ovarian tumors
Methylation profile in benign, borderline and malignant ovarian tumors
Tam, K. F.; Liu, V. W. S.; Liu, S. S.; Tsang, P. C. K.; Cheung, A. N. Y.; Yip, A. M. W.; Ngan, H. Y. S.
profiles in different types of ovarian ...
... Identification of patterns of DNA  methylation 
Monitoring Methylation and Gene Expression in Cancer
Monitoring Methylation and Gene Expression in Cancer
Carraway, Hetty; Herman, James
in higher order eukaryotes has become ...
... Background In higher eukaryotes DNA  methylation 
Growth of the protozoan parasite Entamoeba histolytica in 5-azacytidine has limited effects on parasite gene expression
Growth of the protozoan parasite Entamoeba histolytica in 5-azacytidine has limited effects on parasite gene expression
Ali, Ibne Karim M; Ehrenkaufer, Gretchen M; Hackney, Jason A; Singh, Upinder
regulates important biological functions ...
... that regulates gene expression throughout  methylation 
DNA Methylation and Histone Modifications in Patients With Cancer
DNA Methylation and Histone Modifications in Patients With Cancer
Herranz, Michel; Esteller, Manel
, acetylation, and chromatin remodeling. ...
... 3 lysine 9 (dimethyl-H3K9) and DNA  methylation 
Diverse histone modifications on histone 3 lysine 9 and their relation to DNA methylation in specifying gene silencing
Diverse histone modifications on histone 3 lysine 9 and their relation to DNA methylation in specifying gene silencing
Wu, Jiejun; Wang, Shu-Huei; Potter, Dustin; Liu, Joseph C; Smith, Laura T; Wu, Yue-Zhong; Huang, Tim H-M; Plass, Christoph
cooperate to maintain a repressive mode ...
... (TEs) are a comprehensive target for DNA  methylation 
Rice transposable elements are characterized by various methylation environments in the genome
Rice transposable elements are characterized by various methylation environments in the genome
Takata, Miwako; Kiyohara, Akihiro; Takasu, Atsuko; Kishima, Yuji; Ohtsubo, Hisako; Sano, Yoshio
. ...
... Abnormal patterns of DNA  methylation 
Gender specific differences in levels of DNA methylation at selected loci from human total blood: a tendency toward higher methylation levels in males
Gender specific differences in levels of DNA methylation at selected loci from human total blood: a tendency toward higher methylation levels in males
El-Maarri, Osman; Becker, Tim; Junen, Judith; Manzoor, Syed Saadi; Diaz-Lacava, Amalia; Schwaab, Rainer; Wienker, Thomas; Oldenburg, Johannes
are observed in many diseases such as ...
... the establishment and maintenance of DNA  methylation 
Coordinate regulation of DNA methyltransferase expression during oogenesis
Coordinate regulation of DNA methyltransferase expression during oogenesis
Lucifero, Diana; La Salle, Sophie; Bourc'his, Déborah; Martel, Josée; Bestor, Timothy H; Trasler, Jacquetta M
within repeat elements and imprinted ...
... results have been reported for RASSF1A  methylation 
RASSF1A promoter methylation and expression analysis in normal and neoplastic kidney indicates a role in early tumorigenesis
RASSF1A promoter methylation and expression analysis in normal and neoplastic kidney indicates a role in early tumorigenesis
Peters, Inga; Rehmet, Kristina; Wilke, Nadine; Kuczyk, Markus A; Hennenlotter, Jörg; Eilers, Tyark; Machtens, Stefan; Jonas, Udo; Serth, Jürgen
in normal kidney, thus it is not clear ...
... abundance and susceptibility to DNA  methylation 
Germline methylation patterns inferred from local nucleotide frequency of repetitive sequences in the human genome
Germline methylation patterns inferred from local nucleotide frequency of repetitive sequences in the human genome
Kim, Tae-Min; Chung, Yeun-Jun; Rhyu, Mun-Gan; Jung, Myeong Ho
, interspersed repetitive sequences in ...
... with changes in adipogenic promoter DNA  methylation 
Dynamics of adipogenic promoter DNA methylation during clonal culture of human adipose stem cells to senescence
Dynamics of adipogenic promoter DNA methylation during clonal culture of human adipose stem cells to senescence
Noer, Agate; Boquest, Andrew C; Collas, Philippe
. ...
... from those of smokers. Aberrant promoter  methylation 
Promoter methylation of RASSF1A and DAPK and mutations of K-ras, p53, and EGFR in lung tumors from smokers and never-smokers
Promoter methylation of RASSF1A and DAPK and mutations of K-ras, p53, and EGFR in lung tumors from smokers and never-smokers
Liu, Yang; Gao, Weimin; Siegfried, Jill M; Weissfeld, Joel L; Luketich, James D; Keohavong, Phouthone
and mutations in some oncogenes and tumor ...
... cancer cell lines using RT-PCR and (2)  methylation 
Methylation and Gene Silencing of the Ras-Related GTPase Gene in Lung and Breast Cancers
Methylation and Gene Silencing of the Ras-Related GTPase Gene in Lung and Breast Cancers
Suzuki, Makoto; Shigematsu, Hisayuki; Shames, David S.; Sunaga, Noriaki; Takahashi, Takao; Shivapurkar, Narayan; Iizasa, Toshihiko; Minna, John D.; Fujisawa, Takehiko; Gazdar, Adi F.
status of lung and breast cancers. ...
... of mutations because cytosine base  methylation 
Stem Cell Chronicles: Autobiographies Within Genomes
Stem Cell Chronicles: Autobiographies Within Genomes
Shibata, Darryl; Tavaré, Simon
[6] in certain CpG rich regions ...
... Loss of XAF1 expression through promoter  methylation 
Silencing of the XAF1 gene by promoter hypermethylation in cancer cells and reactivation to TRAIL-sensitization by IFN-β
Silencing of the XAF1 gene by promoter hypermethylation in cancer cells and reactivation to TRAIL-sensitization by IFN-β
Micali, O Cristina; Cheung, Herman H; Plenchette, Stéphanie; Hurley, Sandra L; Liston, Peter; LaCasse, Eric C; Korneluk, Robert G
has been implicated in the process of ...
... and sputum. To date the penetrance of DNA  methylation 
Identification of a panel of sensitive and specific DNA methylation markers for lung adenocarcinoma
Identification of a panel of sensitive and specific DNA methylation markers for lung adenocarcinoma
Tsou, Jeffrey A; Galler, Janice S; Siegmund, Kimberly D; Laird, Peter W; Turla, Sally; Cozen, Wendy; Hagen, Jeffrey A; Koss, Michael N; Laird-Offringa, Ite A
at any single locus has been too low to ...