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... Background  Methylation 
Changes in correlation between promoter methylation and gene expression in cancer
Changes in correlation between promoter methylation and gene expression in cancer
Moarii, Matahi; Boeva, Valentina; Vert, Jean-Philippe; Reyal, Fabien
of high-density CpG regions known as CpG ...
... for eukaryotic gene expression. DNA  methylation 
Genome-Wide Analysis of DNA Methylation Patterns by High-Throughput Sequencing
Genome-Wide Analysis of DNA Methylation Patterns by High-Throughput Sequencing
Baubec, Tuncay; Akalin, Altuna
is the paradigm epigenetic modification ...
... similarities with humans. Aberrant DNA  methylation 
Adult porcine genome-wide DNA methylation patterns support pigs as a biomedical model
Adult porcine genome-wide DNA methylation patterns support pigs as a biomedical model
Schachtschneider, Kyle M.; Madsen, Ole; Park, Chankyu; Rund, Laurie A.; Groenen, Martien A. M.; Schook, Lawrence B.
has been linked to many of these diseases ...
... The computational prediction of DNA  methylation 
Profile analysis and prediction of tissue-specific CpG island methylation classes
Profile analysis and prediction of tissue-specific CpG island methylation classes
Previti, Christopher; Harari, Oscar; Zwir, Igor; del Val, Coral
has become an important topic in the ...
... evidence on the prognostic utility of DNA  methylation 
Methylation markers for prostate cancer prognosis: a systematic review
Methylation markers for prostate cancer prognosis: a systematic review
Chao, Chun; Chi, Margaret; Preciado, Melissa; Black, Mary Helen
markers in prostate cancer and ascertain ...
... Background DNA  methylation 
Tissue-specific variation in DNA methylation levels along human chromosome 1
Tissue-specific variation in DNA methylation levels along human chromosome 1
De Bustos, Cecilia; Ramos, Edward; Young, Janet M; Tran, Robert K; Menzel, Uwe; Langford, Cordelia F; Eichler, Evan E; Hsu, Li; Henikoff, Steve; Dumanski, Jan P; Trask, Barbara J
is a major epigenetic modification ...
... mechanistic underpinnings of differential  methylation 
Integrative epigenomic analysis of differential DNA methylation in urothelial carcinoma
Integrative epigenomic analysis of differential DNA methylation in urothelial carcinoma
Aine, Mattias; Sjödahl, Gottfrid; Eriksson, Pontus; Veerla, Srinivas; Lindgren, David; Ringnér, Markus; Höglund, Mattias
remain poorly understood. ...
... As a major epigenetic component, DNA  methylation 
Reduced representation bisulphite sequencing of ten bovine somatic tissues reveals DNA methylation patterns and their impacts on gene expression
Reduced representation bisulphite sequencing of ten bovine somatic tissues reveals DNA methylation patterns and their impacts on gene expression
Zhou, Yang; Xu, Lingyang; Bickhart, Derek M.; abdel Hay, El Hamidi; Schroeder, Steven G.; Connor, Erin E.; Alexander, Leeson J.; Sonstegard, Tad S.; Van Tassell, Curtis P.; Chen, Hong; Liu, George E.
plays important functions in individual ...
... those encoded in DNA sequence. Cytosine  methylation 
Introduction to Epigenomics and Epigenome-Wide Analysis
Introduction to Epigenomics and Epigenome-Wide Analysis
Fazzari, Melissa J.; Greally, John M.
of DNA at CpG dinucleotides is the most ...
... since the 1990s, promoter CpG island  methylation 
Analysis of RET promoter CpG island methylation using methylation-specific PCR (MSP), pyrosequencing, and methylation-sensitive high-resolution melting (MS-HRM): impact on stage II colon cancer patient outcome
Analysis of RET promoter CpG island methylation using methylation-specific PCR (MSP), pyrosequencing, and methylation-sensitive high-resolution melting (MS-HRM): impact on stage II colon cancer patient outcome
Draht, Muriel X. G.; Smits, Kim M.; Jooste, Valérie; Tournier, Benjamin; Vervoort, Martijn; Ramaekers, Chantal; Chapusot, Caroline; Weijenberg, Matty P.; van Engeland, Manon; Melotte, Veerle
markers have been considered promising ...
... genome-wide studies found that DNA  methylation 
Whole DNA methylome profiling in lung cancer cells before and after epithelial-to-mesenchymal transition
Whole DNA methylome profiling in lung cancer cells before and after epithelial-to-mesenchymal transition
Liu, Fatao; Zhou, Yi; Zhou, Daizhan; Kan, Mengyuan; Niu, Xiaomin; Zhang, Zhou; Zhang, Di; Tao, Liming; He, Lin; Zhan, Lixing; Liu, Yun
was unchanged during EMT induced by TGF-β ...
... Background  Methylation 
Hypomethylation coordinates antagonistically with hypermethylation in cancer development: a case study of leukemia
Hypomethylation coordinates antagonistically with hypermethylation in cancer development: a case study of leukemia
Kushwaha, Garima; Dozmorov, Mikhail; Wren, Jonathan D.; Qiu, Jing; Shi, Huidong; Xu, Dong
changes are frequent in cancers, but ...
... where the epigenetic marks of DNA  methylation 
Placental methylome analysis from a prospective autism study
Placental methylome analysis from a prospective autism study
Schroeder, Diane I.; Schmidt, Rebecca J.; Crary-Dooley, Florence K.; Walker, Cheryl K.; Ozonoff, Sally; Tancredi, Daniel J.; Hertz-Picciotto, Irva; LaSalle, Janine M.
may be useful as risk biomarkers. ...
... potential for the development of new DNA  methylation 
A panel of genes methylated with high frequency in colorectal cancer
A panel of genes methylated with high frequency in colorectal cancer
Mitchell, Susan M; Ross, Jason P; Drew, Horace R; Ho, Thu; Brown, Glenn S; Saunders, Neil FW; Duesing, Konsta R; Buckley, Michael J; Dunne, Rob; Beetson, Iain; Rand, Keith N; McEvoy, Aidan; Thomas, Melissa L; Baker, Rohan T; Wattchow, David A; Young, Graeme P; Lockett, Trevor J; Pedersen, Susanne K; LaPointe, Lawrence C; Molloy, Peter L
biomarkers or panels to improve the ...
... Epigenetic modifications, among these DNA  methylation 
Dynamic DNA Methylation Patterns in Stress Response
Dynamic DNA Methylation Patterns in Stress Response
Viggiano, Luigi; Pinto, Maria Concetta
, represent potentially robust mechanisms ...
... Previous studies have indicated that DNA  methylation 
Widespread recovery of methylation at gametic imprints in hypomethylated mouse stem cells following rescue with DNMT3A2
Widespread recovery of methylation at gametic imprints in hypomethylated mouse stem cells following rescue with DNMT3A2
Thakur, Avinash; Mackin, Sarah-Jayne; Irwin, Rachelle E.; O’Neill, Karla M.; Pollin, Gareth; Walsh, Colum
lost from gDMRs could not be restored by ...
... cytosine ring (referred to as cytosine  methylation 
Chromatin Modifications in Plants
Chromatin Modifications in Plants
Zhang, Xiaoyu
or DNA ...
... array-based analysis of genome-wide DNA  methylation 
Global, cancer-specific microRNA cluster hypomethylation was functionally associated with the development of non-B non-C hepatocellular carcinoma
Global, cancer-specific microRNA cluster hypomethylation was functionally associated with the development of non-B non-C hepatocellular carcinoma
Nojima, Masanori; Matsui, Takeshi; Tamori, Akihiro; Kubo, Shoji; Shirabe, Ken; Kimura, Koichi; Shimada, Mitsuo; Utsunomiya, Tohru; Kondo, Yasuteru; Iio, Etsuko; Naito, Yutaka; Ochiya, Takahiro; Tanaka, Yasuhito
(N = 43 pairs) and mRNA/miRNA expression ...
... and persistence of sex differences in DNA  methylation 
The effects of perinatal testosterone exposure on the DNA methylome of the mouse brain are late-emerging
The effects of perinatal testosterone exposure on the DNA methylome of the mouse brain are late-emerging
Ghahramani, Negar M; Ngun, Tuck C; Chen, Pao-Yang; Tian, Yuan; Krishnan, Sangitha; Muir, Stephanie; Rubbi, Liudmilla; Arnold, Arthur P; de Vries, Geert J; Forger, Nancy G; Pellegrini, Matteo; Vilain, Eric
, we performed genome-wide surveys in ...
... the 5th position of cytosine bases. DNA  methylation 
Establishment and Maintenance of DNA Methylation
Establishment and Maintenance of DNA Methylation
Tajima, Shoji; Kimura, Hironobu; Suetake, Isao
acts as a regulator of gene expression ...
... DNA  methylation 
DNA METHYLTRANSFERASE 1 is involved in mCG and mCCG DNA methylation and is essential for sporophyte development in Physcomitrella patens
DNA METHYLTRANSFERASE 1 is involved in mCG and mCCG DNA methylation and is essential for sporophyte development in Physcomitrella patens
Yaari, Rafael; Noy-Malka, Chen; Wiedemann, Gertrud; Auerbach Gershovitz, Nitzan; Reski, Ralf; Katz, Aviva; Ohad, Nir
has a crucial role in plant development ...
... that individual differences in SLC6A4 DNA  methylation 
Influence of life stress, 5-HTTLPR genotype, and SLC6A4 methylation on gene expression and stress response in healthy Caucasian males
Influence of life stress, 5-HTTLPR genotype, and SLC6A4 methylation on gene expression and stress response in healthy Caucasian males
Duman, Elif A; Canli, Turhan
could be one underlying mechanism by ...
... DNA  methylation 
Lung cancer: From single-gene methylation to methylome profiling
Lung cancer: From single-gene methylation to methylome profiling
Heller, Gerwin; Zielinski, Christoph C.; Zöchbauer-Müller, Sabine
as part of the epigenetic gene-silencing ...
... performed a systematic analysis of DNA  methylation 
DNA methylation of distal regulatory sites characterizes dysregulation of cancer genes
DNA methylation of distal regulatory sites characterizes dysregulation of cancer genes
Aran, Dvir; Sabato, Sivan; Hellman, Asaf
sites connected with gene expression ...
... Background DNA  methylation 
The relationship between DNA methylation, genetic and expression inter-individual variation in untransformed human fibroblasts
The relationship between DNA methylation, genetic and expression inter-individual variation in untransformed human fibroblasts
Wagner, James R; Busche, Stephan; Ge, Bing; Kwan, Tony; Pastinen, Tomi; Blanchette, Mathieu
plays an essential role in the regulation ...