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... phenotypes and can be maintained via  homozygous 
Mouse Models of Receptor Tyrosine Kinases
Mouse Models of Receptor Tyrosine Kinases
Holcmann, Martin; Amberg, Nicole; Drobits, Barbara; Glitzner, Elisabeth; Komposch, Karin; Robson, Jonathan; Savarese, Fabio; Srivatsa, Sriram; Stulnig, Gabriel; Sibilia, Maria
breeding. ...
... vs. CC), recessive model (CC + CT vs. TT),  homozygous 
Association between the MTHFR C677T polymorphism and risk of cancer: evidence from 446 case–control studies
Association between the MTHFR C677T polymorphism and risk of cancer: evidence from 446 case–control studies
Xie, Shu-Zhe; Liu, Zhi-Zhong; Yu, Jun-hua; Liu, Li; Wang, Wei; Xie, Dao-Lin; Qin, Jiang-Bo
model (TT vs. ...
... CI = 1.03–1.12, P h < 0.001, I 2 = 54.2 %;  homozygous 
Association between the CYP1B1 polymorphisms and risk of cancer: a meta-analysis
Association between the CYP1B1 polymorphisms and risk of cancer: a meta-analysis
Liu, Jie-Ying; Yang, Yu; Liu, Zhi-Zhong; Xie, Jian-Jun; Du, Ya-Ping; Wang, Wei
model: OR = 1.09, 95 % CI = 1.02–1.17, P ...
... of homozygotes. Results A scan for  homozygous 
Homozygous haplotype deficiency reveals deleterious mutations compromising reproductive and rearing success in cattle
Homozygous haplotype deficiency reveals deleterious mutations compromising reproductive and rearing success in cattle
Pausch, Hubert; Schwarzenbacher, Hermann; Burgstaller, Johann; Flisikowski, Krzysztof; Wurmser, Christine; Jansen, Sandra; Jung, Simone; Schnieke, Angelika; Wittek, Thomas; Fries, Ruedi
haplotype deficiency in 25,544 Fleckvieh ...
... its unique cerebellar phenotype.  Homozygous 
The Spontaneous Ataxic Mouse Mutant Tippy is Characterized by a Novel Purkinje Cell Morphogenesis and Degeneration Phenotype
The Spontaneous Ataxic Mouse Mutant Tippy is Characterized by a Novel Purkinje Cell Morphogenesis and Degeneration Phenotype
Shih, Evelyn K.; Sekerková, Gabriella; Ohtsuki, Gen; Aldinger, Kimberly A.; Chizhikov, Victor V.; Hansel, Christian; Mugnaini, Enrico; Millen, Kathleen J.
tippy mutant mice are small, ataxic, and ...
...  Homozygous 
Recovery and characterization of homozygous lines from two sweet orange cultivars via anther culture
Recovery and characterization of homozygous lines from two sweet orange cultivars via anther culture
Wang, Shu-Ming; Lan, Hong; Cao, Hong-Bo; Xu, Qiang; Chen, Chun-Li; Deng, Xiu-Xin; Guo, Wen-Wu
genotypes are valuable for breeding and ...
... BB genotype composition (high β-carotene  homozygous 
Interaction of the mutant genes B, ogc, hp and t in the coloring of tomato fruit
Interaction of the mutant genes B, ogc, hp and t in the coloring of tomato fruit
Andrade, Thiago Matos; Maluf, Wilson Roberto; Oliveira, Celso Mattes; Gomes, Luiz Antônio Augusto; Santos, Daniela Costa; Carvalho, Regis de Castro; Gonçalves, Ranoel José de Sousa; Gonçalves Neto, Álvaro Carlos
) were used in hybrid combinations with 7 ...
... pain was reported more often in patients  homozygous 
Relationship between clinical findings and genetic mutations in patients with familial Mediterranean fever
Relationship between clinical findings and genetic mutations in patients with familial Mediterranean fever
Kilic, Ayse; Varkal, Muhammet Ali; Durmus, Mehmet Sait; Yildiz, Ismail; Yıldırım, Zeynep Nagihan Yürük; Turunc, Gorkem; Oguz, Fatma; Sidal, Mujgan; Omeroglu, Rukiye Eker; Emre, Sevinc; Yilmaz, Yasin; Kelesoglu, Fatih Mehmet; Gencay, Genco Ali; Temurhan, Sonay; Aydin, Filiz; Unuvar, Emin
for M694V (61.4 %). ...
... single individual/tissue/organ with cells  homozygous 
Mosaic Analysis in the Drosophila melanogaster Ovary
Mosaic Analysis in the Drosophila melanogaster Ovary
Rubin, Thomas; Huynh, Jean-René
and cells heterozygous for this mutation, ...
... a panel of cell lines partially or fully  homozygous 
Very long haplotype tracts characterized at high resolution from HLA homozygous cell lines
Very long haplotype tracts characterized at high resolution from HLA homozygous cell lines
Norman, Paul J.; Norberg, Steve J.; Nemat-Gorgani, Neda; Royce, Thomas; Hollenbach, Jill A.; Shults Won, Melissa; Guethlein, Lisbeth A.; Gunderson, Kevin L.; Ronaghi, Mostafa; Parham, Peter
for HLA class I and II was assembled over ...
... GCD2-heterozygous (n = 1), and GCD2-  homozygous 
Histone methylation levels correlate with TGFBIp and extracellular matrix gene expression in normal and granular corneal dystrophy type 2 corneal fibroblasts
Histone methylation levels correlate with TGFBIp and extracellular matrix gene expression in normal and granular corneal dystrophy type 2 corneal fibroblasts
Maeng, Yong-Sun; Lee, Ga-Hyun; Choi, Seung-Il; Kim, Kyu Seo; Kim, Eung Kweon
(n = 3) primary human corneal fibroblasts ...
... The selection of  homozygous 
Fast-Tracking Determination of Homozygous Transgenic Lines and Transgene Stacking Using a Reliable Quantitative Real-Time PCR Assay
Fast-Tracking Determination of Homozygous Transgenic Lines and Transgene Stacking Using a Reliable Quantitative Real-Time PCR Assay
Wang, Xianghong; Jiang, Daiming; Yang, Daichang
lines is a crucial step in the ...
... standard type, heterozygous columnar and  homozygous 
Columnar apple primary roots share some features of the columnar-specific gene expression profile of aerial plant parts as evidenced by RNA-Seq analysis
Columnar apple primary roots share some features of the columnar-specific gene expression profile of aerial plant parts as evidenced by RNA-Seq analysis
Petersen, Romina; Djozgic, Haris; Rieger, Benjamin; Rapp, Steffen; Schmidt, Erwin Robert
columnar apple (Malus x domestica) by ...
... for three times. Identification of  homozygous 
Accumulation of the azelaic acid-induced protein AZI1 affects lignin synthesis and deposition in Arabidopsis thaliana
Accumulation of the azelaic acid-induced protein AZI1 affects lignin synthesis and deposition in Arabidopsis thaliana
Gao, Hang; Wang, Xiao-Yan; Han, Yao-Yao; Du, Gai-Liang; Feng, Huan; Xu, Zi-Qin
T-DNA knockout, overexpressing and RNAi ...
... of the lung. Some studies suggest that  homozygous 
Prevalence of Variants in Methylenetetrahydrofolate Reductase and the Severity of Pulmonary Vascular Disease
Prevalence of Variants in Methylenetetrahydrofolate Reductase and the Severity of Pulmonary Vascular Disease
Day, R. W.; Mack, G. K.; Barker, A. M.; Rees, T. Q.; Jorgensen, L. O.; Botto, L. D.
677TT variants and compound heterozygous ...
... this method is efficiency independent.  Homozygous 
High-Resolution Melting Analysis of Single Nucleotide Polymorphisms
High-Resolution Melting Analysis of Single Nucleotide Polymorphisms
Bruzzone, Carol M.; Steer, Clifford J.
MJA and ...
... Key message New gametic  homozygous 
Generation of a homozygous fertilization-defective gcs1 mutant by heat-inducible removal of a rescue gene
Generation of a homozygous fertilization-defective gcs1 mutant by heat-inducible removal of a rescue gene
Nagahara, Shiori; Takeuchi, Hidenori; Higashiyama, Tetsuya
mutants. ...
... a mean read depth of 12. Stretches with  homozygous 
Runs of homozygosity reveal signatures of positive selection for reproduction traits in breed and non-breed horses
Runs of homozygosity reveal signatures of positive selection for reproduction traits in breed and non-breed horses
Metzger, Julia; Karwath, Matthias; Tonda, Raul; Beltran, Sergi; Águeda, Lídia; Gut, Marta; Gut, Ivo Glynne; Distl, Ottmar
genotypes of >40 kb as well as >400 kb ...
... and the corresponding size and number of  homozygous 
Unraveling the genetic landscape of autosomal recessive Charcot-Marie-Tooth neuropathies using a homozygosity mapping approach
Unraveling the genetic landscape of autosomal recessive Charcot-Marie-Tooth neuropathies using a homozygosity mapping approach
Zimoń, Magdalena; Battaloğlu, Esra; Parman, Yesim; Erdem, Sevim; Baets, Jonathan; Vriendt, Els; Atkinson, Derek; Almeida-Souza, Leonardo; Deconinck, Tine; Ozes, Burcak; Goossens, Dirk; Cirak, Sebahattin; Damme, Philip; Shboul, Mohammad; Voit, Thomas; Maldergem, Lionel; Dan, Bernard; El-Khateeb, Mohammed S.; Guergueltcheva, Velina; Lopez-Laso, Eduardo; Goemans, Nathalie; Masri, Amira; Züchner, Stephan; Timmerman, Vincent; Topaloğlu, Haluk; Jonghe, Peter; Jordanova, Albena
regions in each patient or family, which ...
... apple cultivars can be developed carrying  homozygous 
Breeding Elite Lines of Apple Carrying Pyramided Homozygous Resistance Genes Against Apple Scab and Resistance Against Powdery Mildew and Fire Blight
Breeding Elite Lines of Apple Carrying Pyramided Homozygous Resistance Genes Against Apple Scab and Resistance Against Powdery Mildew and Fire Blight
Baumgartner, Isabelle O.; Patocchi, Andrea; Frey, Jürg E.; Peil, Andreas; Kellerhals, Markus
allele sets of specific resistance genes, ...
... or a resistant breeding line known to be  homozygous 
A transposable element insertion in the susceptibility gene CsaMLO8 results in hypocotyl resistance to powdery mildew in cucumber
A transposable element insertion in the susceptibility gene CsaMLO8 results in hypocotyl resistance to powdery mildew in cucumber
Berg, Jeroen A.; Appiano, Michela; Santillán Martínez, Miguel; Hermans, Freddy WK; Vriezen, Wim H.; Visser, Richard GF; Bai, Yuling; Schouten, Henk J.
for the hypocotyl resistance QTL as a ...
... an extra genotyping step to identify  homozygous 
Egg cell-specific promoter-controlled CRISPR/Cas9 efficiently generates homozygous mutants for multiple target genes in Arabidopsis in a single generation
Egg cell-specific promoter-controlled CRISPR/Cas9 efficiently generates homozygous mutants for multiple target genes in Arabidopsis in a single generation
Wang, Zhi-Ping; Xing, Hui-Li; Dong, Li; Zhang, Hai-Yan; Han, Chun-Yan; Wang, Xue-Chen; Chen, Qi-Jun
plants for phenotyping. ...
... are created by hybridization between two  homozygous 
Mapping Populations
Mapping Populations
Singh, B. D.; Singh, A. K.
lines usually having contrasting forms for ...
... a concordance rate of 99.6–99.8 % for  homozygous 
Deep sequencing of Danish Holstein dairy cattle for variant detection and insight into potential loss-of-function variants in protein coding genes
Deep sequencing of Danish Holstein dairy cattle for variant detection and insight into potential loss-of-function variants in protein coding genes
Das, Ashutosh; Panitz, Frank; Gregersen, Vivi Raundahl; Bendixen, Christian; Holm, Lars-Erik
SNPs and 93.3–96.5 % for heterozygous ...
... linked to Female (F) locus to distinguish  homozygous 
Development and characterization of a co-dominant molecular marker via sequence analysis of a genomic region containing the Female (F) locus in cucumber (Cucumis sativus L.)
Development and characterization of a co-dominant molecular marker via sequence analysis of a genomic region containing the Female (F) locus in cucumber (Cucumis sativus L.)
Win, Khin Thanda; Zhang, Chunying; Song, Kihwan; Lee, Jeong Hwan; Lee, Sanghyeob
and heterozygous gynoecious lines for ...