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... of male Zucker diabetic fatty (ZDF) rats  homozygous 
The equivocal metabolic response to endotoxaemia in type 2 diabetic and obese ZDF rats
The equivocal metabolic response to endotoxaemia in type 2 diabetic and obese ZDF rats
Belabed, L.; Senon, G.; Blanc, M.-C.; Paillard, A.; Cynober, L.; Darquy, S.
for non-functional leptin receptors ...
... an autosomal recessive disorder caused by  homozygous 
Autoimmune Liver Disease
Autoimmune Liver Disease
Mieli-Vergani, Giorgina; Vergani, Diego
mutations in the AIRE1 gene and ...
... homologue was identified in mammals and  homozygous 
The Copper Metallome in Eukaryotic Cells
The Copper Metallome in Eukaryotic Cells
Vest, Katherine E.; Hashemi, Hayaa F.; Cobine, Paul A.
deletion of COX17 in mice is embryonically ...
... has been carried out in a patient  homozygous 
Liver Transplantation for Transthyretin Amyloidosis
Liver Transplantation for Transthyretin Amyloidosis
Ericzon, Bo-Göran; Lundgren, Erik; Suhr, Ole B.
for the ATTR Val122Ile mutation without ...
... data above revealing that patients with  homozygous 
Sepsis
Sepsis
Mello, Patricia; Gusmao-Flores, Dimitri; Dellinger, R. Phillip
for minor frequency G allele at ...
... known for 28 patients. Of these 16 were  homozygous 
Efficacy and outcome of expanded newborn screening for metabolic diseases - Report of 10 years from South-West Germany *
Efficacy and outcome of expanded newborn screening for metabolic diseases - Report of 10 years from South-West Germany *
Lindner, Martin; Gramer, Gwendolyn; Haege, Gisela; Fang-Hoffmann, Junmin; Schwab, Karl O; Tacke, Uta; Trefz, Friedrich K; Mengel, Eugen; Wendel, Udo; Leichsenring, Michael; Burgard, Peter; Hoffmann, Georg F
for the common mutation c.985A >G ...
... investigated. Material and methods Animals  Homozygous 
Nitric oxide-releasing agent, LA419, reduces atherogenesis in apolipoprotein E-deficient mice
Nitric oxide-releasing agent, LA419, reduces atherogenesis in apolipoprotein E-deficient mice
Carnicer, Ricardo; Guillén, Natalia; Arbonés-Mainar, José M.; Navarro, María A.; Guzmán, Mario A.; Barranquero, Cristina; Arnal, Carmen; Gascón, Sonia; Acín, Sergio; Mourelle, Marisabel; Osada, Jesús
apoE-deficient mice, hybrids of C57BL/6J ...
... diseases [15]. For example, the germline  homozygous 
Epigenetic regulation of lncRNA connects ubiquitin-proteasome system with infection-inflammation in preterm births and preterm premature rupture of membranes
Epigenetic regulation of lncRNA connects ubiquitin-proteasome system with infection-inflammation in preterm births and preterm premature rupture of membranes
Luo, Xiucui; Pan, Jing; Wang, Leilei; Wang, Peirong; Zhang, Meijiao; Liu, Meilin; Dong, Ziqing; Meng, Qian; Tao, Xuguang; Zhao, Xinliang; Zhong, Julia; Ju, Weina; Gu, Yang; Jenkins, Edmund C; Brown, W Ted; Shi, Qingxi; Zhong, Nanbert
2 bp (TT) deletion of the snoRNA U50 is ...
... the R3 allele, were generated by crossing  homozygous 
Progressive ganglion cell loss and optic nerve degeneration in DBA/2J mice is variable and asymmetric
Progressive ganglion cell loss and optic nerve degeneration in DBA/2J mice is variable and asymmetric
Schlamp, Cassandra L; Li, Yan; Dietz, Joel A; Janssen, Katherine T; Nickells, Robert W
animals (Fem1cR3/R3) with wild-type D2 ...
... have loss of SMAD4, with nearly 30% having  homozygous 
Transforming Growth Factor β
Transforming Growth Factor β
Principe, Daniel R.; Mangan, Riley J.; Grippo, Paul J.
deletion and the remaining 25% having loss ...
... s.str. was equal or close to zero (  homozygous 
Allozyme Variation in Diploid, Polyploid and Mixed-Ploidy Populations of the Pilosella alpicola Group (Asteraceae): Relation to Morphology, Origin of Polyploids and Breeding System
Allozyme Variation in Diploid, Polyploid and Mixed-Ploidy Populations of the Pilosella alpicola Group (Asteraceae): Relation to Morphology, Origin of Polyploids and Breeding System
Šingliarová, Barbora; Chrtek, Jindřich; Plačková, Ivana; Mráz, Patrik
) or one (heterozygous, see Table  4 ). ...
... Cleopatra mandarin (29%) due to the high  homozygous 
Transferability of the EST-SSRs developed on Nules clementine (Citrus clementina Hort ex Tan) to other Citrus species and their effectiveness for genetic mapping
Transferability of the EST-SSRs developed on Nules clementine (Citrus clementina Hort ex Tan) to other Citrus species and their effectiveness for genetic mapping
Luro, François L; Costantino, Gilles; Terol, Javier; Argout, Xavier; Allario, Thierry; Wincker, Patrick; Talon, Manuel; Ollitrault, Patrick; Morillon, Raphael
level of these genotypes. ...
... host, or when the donor is  homozygous 
Graft-Versus-Host Disease
Graft-Versus-Host Disease
Pompei, David; Russell, Kathryn J.; Pereira, Frederick A.
for an HLA class 1 haplotype of the ...
... to those with CC. In addition, the  homozygous 
Association of MTHFR C677T polymorphism and risk of cerebrovascular disease in Chinese population: an updated meta-analysis
Association of MTHFR C677T polymorphism and risk of cerebrovascular disease in Chinese population: an updated meta-analysis
Zhang, Ming-Jie; Li, Jing-Cheng; Yin, Yan-Wei; Li, Bing-Hu; Liu, Yun; Liao, Shao-Qiong; Gao, Chang-Yue; Zhang, Li-Li
TT genotype has a higher risk than the ...
... strain shhshh -tm6Amc-/J (heterozygous and  homozygous 
Reconstitution of a Patterned Neural Tube from Single Mouse Embryonic Stem Cells
Reconstitution of a Patterned Neural Tube from Single Mouse Embryonic Stem Cells
Ishihara, Keisuke; Ranga, Adrian; Lutolf, Matthias P.; Tanaka, Elly M.; Meinhardt, Andrea
cells tested). 2. Trypsin/EDTA may also be ...
... Mutants exhibit a lower cold tolerance  Homozygous 
Brown adipose tissue specific lack of uncoupling protein 3 is associated with impaired cold tolerance and reduced transcript levels of metabolic genes
Brown adipose tissue specific lack of uncoupling protein 3 is associated with impaired cold tolerance and reduced transcript levels of metabolic genes
Nau, Kerstin; Fromme, Tobias; Meyer, Carola W.; Praun, Christa; Heldmaier, Gerhard; Klingenspor, Martin
wildtype and mutant hamsters (n = 6 each) ...
... tract (Beck et al. 1999). Cdx2  homozygous 
Cellular Reprogramming During Mouse Development
Cellular Reprogramming During Mouse Development
Burke, Zoë D.; Miron-Buchacra, Gabriela; Tosh, David
-null mice die due to a failure to undergo ...
... without any other genetic disruptions,  homozygous 
CRISPR: a versatile tool for both forward and reverse genetics research
CRISPR: a versatile tool for both forward and reverse genetics research
Gurumurthy, Channabasavaiah B.; Grati, M’hamed; Ohtsuka, Masato; Schilit, Samantha L. P.; Quadros, Rolen M.; Liu, Xue Zhong
mutant mice in the G0 generation, multiple ...
... with one microsatellite band are  homozygous 
Population genetic structure of the sea bass (Lateolabrax japonicus) in Korea based on multiplex PCR assays with 12 polymorphic microsatellite markers
Population genetic structure of the sea bass (Lateolabrax japonicus) in Korea based on multiplex PCR assays with 12 polymorphic microsatellite markers
An, Hye Suck; Lee, Jang Wook; Kim, Hee Yong; Kim, Jong Bin; Chang, Dae Soo; Park, Jung Youn; Myeong, Jeong In; An, Chul Min
for the allele F ST Single-locus, No ...
... plants possibly with the bip gene in the  homozygous 
Morphological characterisation and genetic analysis of a bi-pistil mutant (bip) in Medicago truncatula Gaertn.
Morphological characterisation and genetic analysis of a bi-pistil mutant (bip) in Medicago truncatula Gaertn.
Nair, Ramakrishnan M.; Peck, David M.; Dundas, Ian S.; Samac, Deborah A.; Moore, Adam; Randles, John W.
condition could be due to the effect of ...
... activates STAT3 in the pancreas and  homozygous 
Could Signal Transducer and Activator of Transcription 3 be a Therapeutic Target in Obesity-Related Gastrointestinal Malignancy?
Could Signal Transducer and Activator of Transcription 3 be a Therapeutic Target in Obesity-Related Gastrointestinal Malignancy?
O’Sullivan, Katie E.; Reynolds, John V.; O’Hanlon, Ciara; O’Sullivan, Jacintha N.; Lysaght, Joanne
deletion of SOCS3 in the pancreas results ...
... A9, A25, A26, and A32 to generate the T3  homozygous 
Modest calcium increase in tomatoes expressing a variant of Arabidopsis cation/H+ antiporter
Modest calcium increase in tomatoes expressing a variant of Arabidopsis cation/H+ antiporter
Chung, Mi Young; Han, Jeung-Sul; Giovannoni, James; Liu, Yang; Kim, Chang Kil; Lim, Ki Byung; Chung, Jae Dong
progenies along with T1 and T2 ...
... it has been shown that individuals  homozygous 
Central Nervous System Inflammation and Cholesterol Metabolism Alterations in the Pathogenesis of Alzheimer’s Disease and Their Diagnostic and Therapeutic Implications
Central Nervous System Inflammation and Cholesterol Metabolism Alterations in the Pathogenesis of Alzheimer’s Disease and Their Diagnostic and Therapeutic Implications
Rojo, Leonel E.; Fernández, Jorge; Jiménez, José; Maccioni, Andrea A.; Sekler, Alejandra; Kuljis, Rodrigo O.; Maccioni, Ricardo B.
for the IL-1α –889*1 allele decline more ...
... and interbred each genotype to produce  homozygous 
Characterization of the nociceptin receptor (ORL-1) agonist, Ro64-6198, in tests of anxiety across multiple species
Characterization of the nociceptin receptor (ORL-1) agonist, Ro64-6198, in tests of anxiety across multiple species
Varty, G. B.; Hyde, L. A.; Hodgson, R. A.; Lu, S. X.; McCool, M. F.; Kazdoba, T. M.; Vecchio, R. A.; Guthrie, D. H.; Pond, A. J.; Grzelak, M. E.; Xu, X.; Korfmacher, W. A.; Tulshian, D.; Parker, E. M.; Higgins, G. A.
WT and ORL-1 KO lines. ...
... determined. At each locus a single peak (  homozygous 
Chimerism Analysis Following Hematopoietic Stem Cell Transplantation
Chimerism Analysis Following Hematopoietic Stem Cell Transplantation
Murphy, Kathleen M.
) or two peaks (heterozygous) are ...