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... for exon 26 alone. We also considered the  homozygous 
Modelling the influence of MDR1 polymorphism on digoxin pharmacokinetic parameters
Modelling the influence of MDR1 polymorphism on digoxin pharmacokinetic parameters
Comets, Emmanuelle; Verstuyft, Céline; Lavielle, Marc; Jaillon, Patrice; Becquemont, Laurent; Mentré, France
wild-type diplotype (combined genotype) ...
... et al. 2008). zatoichi (zat) mutants are  homozygous 
The Genetics of Outer Segment Morphogenesis in Zebrafish
The Genetics of Outer Segment Morphogenesis in Zebrafish
Reynolds, Alison L.; Blacque, Oliver E.; Kennedy, Breandán N.
for a null mutation in the gene encoding ...
... of the STAT5B gene revealed a novel  homozygous 
Translational Highlights
Translational Highlights
missense mutation, p.Phe646Ser, located ...
... system, as described previously [40]. A  homozygous 
Genome-wide gene responses in a transgenic rice line carrying the maize resistance gene Rxo1 to the rice bacterial streak pathogen, Xanthomonas oryzae pv. oryzicola
Genome-wide gene responses in a transgenic rice line carrying the maize resistance gene Rxo1 to the rice bacterial streak pathogen, Xanthomonas oryzae pv. oryzicola
Zhou, Yong-Li; Xu, Mei-Rong; Zhao, Ming-Fu; Xie, Xue-Wen; Zhu, Ling-Hua; Fu, Bin-Ying; Li, Zhi-Kang
T4 line containing a single copy of Rxo1 ...
... PCR-based screening was used to identify  homozygous 
Peroxisomal hydroxypyruvate reductase is not essential for photorespiration in Arabidopsis but its absence causes an increase in the stoichiometry of photorespiratory CO2 release
Peroxisomal hydroxypyruvate reductase is not essential for photorespiration in Arabidopsis but its absence causes an increase in the stoichiometry of photorespiratory CO2 release
Cousins, Asaph B.; Walker, Berkley J.; Pracharoenwattana, Itsara; Smith, Steven M.; Badger, Murray R.
plants for T-DNA insertions, and mutants ...
... cleidocranial dysplasia [10], while  homozygous 
Overexpression of Runx2 and MKP-1 Stimulates Transdifferentiation of 3T3-L1 Preadipocytes into Bone-Forming Osteoblasts In Vitro
Overexpression of Runx2 and MKP-1 Stimulates Transdifferentiation of 3T3-L1 Preadipocytes into Bone-Forming Osteoblasts In Vitro
Takahashi, Tomihisa
mutation in mice results in a complete ...
... from a cross of cals5-3 to wild-type; 15  homozygous 
Callose (β-1,3 glucan) is essential for Arabidopsispollen wall patterning, but not tube growth
Callose (β-1,3 glucan) is essential for Arabidopsispollen wall patterning, but not tube growth
Nishikawa, Shuh-ichi; Zinkl, Gregory M; Swanson, Robert J; Maruyama, Daisuke; Preuss, Daphne
mutant lines (verified by PCR) lacked ...
... with Myc to promote mammary tumorigenesis.  Homozygous 
Cell Polarity in Mammary Gland Morphogenesis and Breast Cancer
Cell Polarity in Mammary Gland Morphogenesis and Breast Cancer
Rejon, Carlis; McCaffrey, Luke
deletion of Lkb1 (also called Par4) from ...
... It has also been reported that subjects  homozygous 
Bisretinoids of RPE Lipofuscin: Trigger for Complement Activation in Age-Related Macular Degeneration
Bisretinoids of RPE Lipofuscin: Trigger for Complement Activation in Age-Related Macular Degeneration
Sparrow, Janet R.
for the risk allele of CFH (CC) and who ...
... [134]. GBA is a lysosomal enzyme whose  homozygous 
Exploring the Role of Autophagy in the Pathogenesis of Rotenone-induced Toxicity
Exploring the Role of Autophagy in the Pathogenesis of Rotenone-induced Toxicity
Sala, Gessica; Stefanoni, Giovanni; Marinig, Daniele; Ferrarese, Carlo
mutations are responsible for Gaucher ...
... accessions were diploid, multigerm, and  homozygous 
Molecular markers for improving control of soil-borne pathogen Fusarium oxysporum in sugar beet
Molecular markers for improving control of soil-borne pathogen Fusarium oxysporum in sugar beet
De Lucchi, Chiara; Stevanato, Piergiorgio; Hanson, Linda; McGrath, Mitch; Panella, Lee; De Biaggi, Marco; Broccanello, Chiara; Bertaggia, Marco; Sella, Luca; Concheri, Giuseppe
for resistance to rhizomania (Rz1). ...
... of low circulating hepcidin. Mice with  homozygous 
Iron and the immune system
Iron and the immune system
Ward, Roberta J.; Crichton, Robert R.; Taylor, Deanna L.; Corte, Laura Della; Srai, Surjit K.; Dexter, David T.
disruption of the hfe gene show low ...
... Zucker fatty fa/fa rats have a genetically  homozygous 
Deficient hippocampal insulin signaling and augmented Tau phosphorylation is related to obesity- and age-induced peripheral insulin resistance: a study in Zucker rats
Deficient hippocampal insulin signaling and augmented Tau phosphorylation is related to obesity- and age-induced peripheral insulin resistance: a study in Zucker rats
Špolcová, Andrea; Mikulášková, Barbora; Kršková, Katarína; Gajdošechová, Lucia; Zórad, Štefan; Olszanecki, Rafał; Suski, Maciej; Bujak-Giżycka, Beata; Železná, Blanka; Maletínská, Lenka
leptin receptor mutation that results in ...
... of one Ae. tauschii chromosome in the  homozygous 
Molecular mapping of quantitative trait loci (QTLs) controlling aluminium tolerance in bread wheat
Molecular mapping of quantitative trait loci (QTLs) controlling aluminium tolerance in bread wheat
Navakode, S.; Weidner, A.; Lohwasser, U.; Röder, M. S.; Börner, A.
state in a cv. ...
... in parentheses: (11) and (22) are  homozygous 
Simulating Linkage Disequilibrium Structures in a Human Population for SNP Association Studies
Simulating Linkage Disequilibrium Structures in a Human Population for SNP Association Studies
Yuan, Xiguo; Zhang, Junying; Wang, Yue
genotypes; (12) is the heterozygous ...
... (PWV) and augmentation index compared to  homozygous 
Salt controls endothelial and vascular phenotype
Salt controls endothelial and vascular phenotype
Kusche-Vihrog, Kristina; Schmitz, Boris; Brand, Eva
C allele carriers [81]. ...
... time, and space in the production of  homozygous 
Beads and Special Applications of Polymers for Agricultural Uses
Beads and Special Applications of Polymers for Agricultural Uses
Nussinovitch, Amos
lines of each genotype. ...
... of prothrombin. We found no patients  homozygous 
Thrombotic gene polymorphisms and postoperative outcome after coronary artery bypass graft surgery
Thrombotic gene polymorphisms and postoperative outcome after coronary artery bypass graft surgery
Emiroglu, Ozan; Durdu, Serkan; Egin, Yonca; Akar, Ahmet R.; Alakoc, Yesim D.; Zaim, Cagin; Ozyurda, Umit; Akar, Nejat
for FVL and PT G20210A. ...
... resources facilitate the generation of  homozygous 
The mammalian gene function resource: the international knockout mouse consortium
The mammalian gene function resource: the international knockout mouse consortium
Bradley, Allan; Anastassiadis, Konstantinos; Ayadi, Abdelkader; Battey, James F.; Bell, Cindy; Birling, Marie-Christine; Bottomley, Joanna; Brown, Steve D.; Bürger, Antje; Bult, Carol J.; Bushell, Wendy; Collins, Francis S.; Desaintes, Christian; Doe, Brendan; Economides, Aris; Eppig, Janan T.; Finnell, Richard H.; Fletcher, Colin; Fray, Martin; Frendewey, David; Friedel, Roland H.; Grosveld, Frank G.; Hansen, Jens; Hérault, Yann; Hicks, Geoffrey; Hörlein, Andreas; Houghton, Richard; Hrabé de Angelis, Martin; Huylebroeck, Danny; Iyer, Vivek; Jong, Pieter J.; Kadin, James A.; Kaloff, Cornelia; Kennedy, Karen; Koutsourakis, Manousos; Kent Lloyd, K. C.; Marschall, Susan; Mason, Jeremy; McKerlie, Colin; McLeod, Michael P.; Melchner, Harald; Moore, Mark; Mujica, Alejandro O.; Nagy, Andras; Nefedov, Mikhail; Nutter, Lauryl M.; Pavlovic, Guillaume; Peterson, Jane L.; Pollock, Jonathan; Ramirez-Solis, Ramiro; Rancourt, Derrick E.; Raspa, Marcello; Remacle, Jacques E.; Ringwald, Martin; Rosen, Barry; Rosenthal, Nadia; Rossant, Janet; Ruiz Noppinger, Patricia; Ryder, Ed; Schick, Joel Zupicich; Schnütgen, Frank; Schofield, Paul; Seisenberger, Claudia; Selloum, Mohammed; Simpson, Elizabeth M.; Skarnes, William C.; Smedley, Damian; Stanford, William L.; Francis Stewart, A.; Stone, Kevin; Swan, Kate; Tadepally, Hamsa; Teboul, Lydia; Tocchini-Valentini, Glauco P.; Valenzuela, David; West, Anthony P.; Yamamura, Ken-ichi; Yoshinaga, Yuko; Wurst, Wolfgang
mutant ES cells by retargeting the second ...
... development and male fertility, but a  homozygous 
Gene trap mutation of murine Outer dense fiber protein-2 gene can result in sperm tail abnormalities in mice with high percentage chimaerism
Gene trap mutation of murine Outer dense fiber protein-2 gene can result in sperm tail abnormalities in mice with high percentage chimaerism
Tarnasky, Heide; Cheng, Min; Ou, Young; Thundathil, Jacob C; Oko, Richard; van der Hoorn, Frans A
interruption of the Odf2 gene is ...
... colonies and from all other colonies were  homozygous 
High mating frequency and variation with lineage ratio in dependent-lineage harvester ants
High mating frequency and variation with lineage ratio in dependent-lineage harvester ants
Suni, S. S.; Eldakar, O. T.
for loci diagnostic for lineage. ...
... appeared to be conditioned by a  homozygous 
Breeding for Insect Resistance in Mung Bean and Urd Bean
Breeding for Insect Resistance in Mung Bean and Urd Bean
Cheema, Harpreet Kaur; Pratap, Aditya; Sujayanand, G. K.
recessive gene (Fernandez and Talekar ...
... insertions led to male sterility, with  homozygous 
LAP3, a novel plant protein required for pollen development, is essential for proper exine formation
LAP3, a novel plant protein required for pollen development, is essential for proper exine formation
Dobritsa, Anna A.; Nishikawa, Shuh-Ichi; Preuss, Daphne; Urbanczyk-Wochniak, Ewa; Sumner, Lloyd W.; Hammond, Adam; Carlson, Ann L.; Swanson, Robert J.
plants having brown, shriveled anthers and ...
... activity in wild-type mice but not mice  homozygous 
Delayed Timing of Eating: Impact on Weight and Metabolism
Delayed Timing of Eating: Impact on Weight and Metabolism
Allison, Kelly C.; Goel, Namni; Ahima, Rexford S.
for a null mutation of gamma isotype of ...
... with hypomorphic mutations of STAT3. As  homozygous 
Janus Kinases (JAKs)/STAT Pathway
Janus Kinases (JAKs)/STAT Pathway
Afzali, Behdad; John, Susan
mutations of STAT3 would be predicted to ...