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... haemolytic effects in the G6PD-deficient  homozygous 
Dapsone Therapy for Malaria During Pregnancy
Dapsone Therapy for Malaria During Pregnancy
Brabin, Bernard J.; Eggelte, Teunis A.; Parise, Monica; Verhoeff, Francine
female or hemizygous male fetus. ...
... Animals Male wild-type (PPARα+/+) and  homozygous 
PPARα downregulates airway inflammation induced by lipopolysaccharide in the mouse
PPARα downregulates airway inflammation induced by lipopolysaccharide in the mouse
Delayre-Orthez, Carine; Becker, Julien; Guenon, Isabelle; Lagente, Vincent; Auwerx, Johan; Frossard, Nelly; Pons, Françoise
knockout (PPARα-/-) mice (SV/129/C57BL/6) ...
... of two independent PCR replicates, and  homozygous 
Paternity alone does not predict long-term investment in juveniles by male baboons
Paternity alone does not predict long-term investment in juveniles by male baboons
Moscovice, Liza R.; Heesen, Marlies; Fiore, Anthony; Seyfarth, Robert M.; Cheney, Dorothy L.
allele calls were confirmed with a minimum ...
... (SANDO) SANDO is frequently caused by  homozygous 
Genetics of Recessive Ataxias
Genetics of Recessive Ataxias
Klebe, Stephan; Anheim, Mathieu
or compound heterozygous mutation in the ...
... repressive complex 2(PRC2)) [91]. Targeted  homozygous 
Sensing and Remembering Cellular States Through Chromatin
Sensing and Remembering Cellular States Through Chromatin
Jiang, Shanxi; Vondriska, Thomas M.
deletion of Fendrr in mouse, another ...
... 11q13 [8], and affected individuals carry  homozygous 
CFEOM1, the classic familial form of congenital fibrosis of the extraocular muscles, is genetically heterogeneous but does not result from mutations in ARIX
CFEOM1, the classic familial form of congenital fibrosis of the extraocular muscles, is genetically heterogeneous but does not result from mutations in ARIX
Engle, Elizabeth C; McIntosh, Nathalie; Yamada, Koki; Lee, Bjorn A; Johnson, Roger; O'Keefe, Michael; Letson, Robert; London, Arnold; Ballard, Evan; Ruttum, Mark; Matsumoto, Naomichi; Saito, Nakamichi; Collins, Mary; Morris, Lisa; Monte, Del Monte; Magli, Adriano; de Berardinis, Teresa
mutations in ARIX[5]. ...
... more appealing since all subjects were  homozygous 
Association of IREB2 and CHRNA3polymorphisms with airflow obstruction in severe alpha-1 antitrypsin deficiency
Association of IREB2 and CHRNA3polymorphisms with airflow obstruction in severe alpha-1 antitrypsin deficiency
Kim, Woo Jin; Wood, Alice M; Barker, Alan F; Brantly, Mark L; Campbell, Edward J; Eden, Edward; McElvaney, Gerard; Rennard, Stephen I; Sandhaus, Robert A; Stocks, James M; Stoller, James K; Strange, Charlie; Turino, Gerard; Silverman, Edwin K; Stockley, Robert A; DeMeo, Dawn L
recessive for the AAT risk locus (PI ZZ). ...
... gene knockout techniques in the mouse. A  homozygous 
Signaling through Galpha12/13 and RGS-RhoGEFs
Signaling through Galpha12/13 and RGS-RhoGEFs
Hajicek, Nicole; Kreutz, Barry; Kozasa, Tohru
deficiency of Gα13 in mice impairs the ...
... loss of SMAD4, with nearly 30 % having  homozygous 
Transforming Growth Factor β
Transforming Growth Factor β
Principe, Daniel R.; Mangan, Riley J.; Grippo, Paul J.
deletion and the remaining 25 % having ...
... developing breast cancer as women who are  homozygous 
A comprehensive analysis of the androgen receptor gene and risk of breast cancer: results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3)
A comprehensive analysis of the androgen receptor gene and risk of breast cancer: results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3)
Cox, David G; Blanché, Hélène; Pearce, Celeste L; Calle, Eugenia E; Colditz, Graham A; Pike, Malcolm C; Albanes, Demetrius; Allen, Naomi E; Amiano, Pilar; Berglund, Goran; Boeing, Heiner; Buring, Julie; Burtt, Noel; Canzian, Federico; Chanock, Stephen; Clavel-Chapelon, Françoise; Feigelson, Heather Spencer; Freedman, Matthew; Haiman, Christopher A; Hankinson, Susan E; Henderson, Brian E; Hoover, Robert; Hunter, David J; Kaaks, Rudolf; Kolonel, Laurence; Kraft, Peter; LeMarchand, Loic; Lund, Eiliv; Palli, Domenico; Peeters, Petra HM; Riboli, Elio; Stram, Daniel O; Thun, Michael; Tjonneland, Anne; Trichopoulos, Dimitrios; Yeager, Meredith; the Breast and Prostate Cancer Cohort Consortium
for the same allele, as approximately half ...
... and lung fibrosis in mice [76]. Mice with  homozygous 
Advances in mechanisms of repair and remodelling in acute lung injury
Advances in mechanisms of repair and remodelling in acute lung injury
Dos Santos, Claudia C.
deletion of the plasminogen activator ...
... foxP2 gene (Groszer et al. 2008). Because  homozygous 
Why the Caged Mouse Sings: Studies of the Mouse Ultrasonic Song System and Vocal Behavior
Why the Caged Mouse Sings: Studies of the Mouse Ultrasonic Song System and Vocal Behavior
Arriaga, Gustavo
inactivations of foxP2 are typically ...
... than that seen in patients who are  homozygous 
Clinical Pharmacokinetics and Pharmacodynamics of Clopidogrel
Clinical Pharmacokinetics and Pharmacodynamics of Clopidogrel
Jiang, Xi-Ling; Samant, Snehal; Lesko, Lawrence J.; Schmidt, Stephan
for CES1 143G (wild-type) [68]. ...
... For this purpose heterozygous and  homozygous 
Apolipoprotein A1 −75 G/A and +83 C/T polymorphisms: susceptibility and prognostic implications in breast cancer
Apolipoprotein A1 −75 G/A and +83 C/T polymorphisms: susceptibility and prognostic implications in breast cancer
Hamrita, Bechr; Nasr, Hela Ben; Gabbouj, Sallouha; Bouaouina, Noureddine; Chouchane, Lotfi; Chahed, Karim
variant genotypes were combined for the ...
... photosynthesis effects. We used both  homozygous 
Mahalanobis distance screening of Arabidopsis mutants with chlorophyll fluorescence
Mahalanobis distance screening of Arabidopsis mutants with chlorophyll fluorescence
Codrea, Marius C.; Hakala-Yatkin, Marja; Kårlund-Marttila, Anna; Nedbal, Ladislav; Aittokallio, Tero; Nevalainen, Olli S.; Tyystjärvi, Esa
lines with regard to the mutation, and ...
... of cardiac contractile properties [55].  Homozygous 
The sodium/calcium exchanger family—SLC8
The sodium/calcium exchanger family—SLC8
Quednau, Beate D.; Nicoll, Debora A.; Philipson, Kenneth D.
NCX1 knockout mice are embryonic lethal at ...
... C1311T G6PD polymorphism; her mother was  homozygous 
Clonality Studies in Cancer Based on X Chromosome Inactivation Phenomenon
Clonality Studies in Cancer Based on X Chromosome Inactivation Phenomenon
Phelan, John T., II; Prchal, Josef T.
for the C allele and her father was ...
... of northern European ancestry) are  homozygous 
Developmental genetics of the COPD lung
Developmental genetics of the COPD lung
Probert, Kelly; Miller, Suzanne; Kheirallah, Abdul Kader; Hall, Ian P.
for a deleterious mutation in SERPINA1 ...
... α1 chain further, we made use of α1LG4-5  homozygous 
Laminin α1 domains LG4-5 are essential for the complete differentiation of visceral endoderm
Laminin α1 domains LG4-5 are essential for the complete differentiation of visceral endoderm
Åkerlund, Mikael; Carmignac, Virginie; Schéele, Susanne; Durbeej, Madeleine
null (α1LG4-5-/-) ES cells previously ...
... phenotype was observed in embryos with a  homozygous 
Dissecting microRNA-mediated regulation of stemness, reprogramming, and pluripotency
Dissecting microRNA-mediated regulation of stemness, reprogramming, and pluripotency
Lee, Young Jin; Ramakrishna, Suresh; Chauhan, Himanshu; Park, Won Sun; Hong, Seok-Ho; Kim, Kye-Seong
loss of the miR-290–295 locus that also ...
... PCR genotyping was used to identify  homozygous 
A mitochondrial alkaline/neutral invertase isoform (A/N-InvC) functions in developmental energy-demanding processes in Arabidopsis
A mitochondrial alkaline/neutral invertase isoform (A/N-InvC) functions in developmental energy-demanding processes in Arabidopsis
Martín, Mariana L.; Lechner, Leandra; Zabaleta, Eduardo J.; Salerno, Graciela L.
plants for the T-DNA insertion in ...
... plants can be self-fertilized to produce  homozygous 
Production of Recombinant Antibodies in Plant Suspension Cultures
Production of Recombinant Antibodies in Plant Suspension Cultures
Drossard, Jürgen; Liao, Yu-Cai; Fischer, Rainer
offspring in order to increase production ...
... function than in individuals who are  homozygous 
Risk for rheumatic disease in relation to ethnicity and admixture
Risk for rheumatic disease in relation to ethnicity and admixture
Molokhia, Mariam; McKeigue, Paul
at these loci, the risk will be higher in ...
... has been studied in patients with  homozygous 
Body iron metabolism and pathophysiology of iron overload
Body iron metabolism and pathophysiology of iron overload
Kohgo, Yutaka; Ikuta, Katsuya; Ohtake, Takaaki; Torimoto, Yoshihiro; Kato, Junji
β-thalassemia. ...
... until plants formed seeds. To select  homozygous 
Ectopic expression of a LEA protein gene TsLEA1 from Thellungiella salsuginea confers salt-tolerance in yeast and Arabidopsis
Ectopic expression of a LEA protein gene TsLEA1 from Thellungiella salsuginea confers salt-tolerance in yeast and Arabidopsis
Zhang, Yiyue; Li, Yin; Lai, Jianbin; Zhang, Huawei; Liu, Yuanyuan; Liang, Liming; Xie, Qi
lines, T2 generation seeds were analyzed ...