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... is lethal [34, 35]. Mouse embryos carrying  homozygous 
Role of DNA Methylation and Epigenetics in Stem Cells
Role of DNA Methylation and Epigenetics in Stem Cells
Thyagarajan, Bhaskar; Rao, Mahendra
deletions for Dnmt1 and Dnmt3b die before ...
... by TGFβ1 Panc-1 + (WT) + BxPC-3 - (  homozygous 
TGFβ1 signaling via αVβ6 integrin
TGFβ1 signaling via αVβ6 integrin
Kracklauer, Martin P; Schmidt, Christian; Sclabas, Guido M
deleted) + Capan-1 - (frame shift ...
... common non-expressers (carriers of the  homozygous 
CYP3A genotypes of donors but not those of the patients increase the risk of acute rejection in renal transplant recipients on calcineurin inhibitors: a pilot study
CYP3A genotypes of donors but not those of the patients increase the risk of acute rejection in renal transplant recipients on calcineurin inhibitors: a pilot study
Gervasini, Guillermo; García-Pino, Guadalupe; Vergara, Esther; Mota-Zamorano, Sonia; García-Cerrada, Montserrat; Luna, Enrique
CYP3A5*3/*3 genotype) [6, 7]. ...
... were subsequently intercrossed to generate  homozygous 
The Role of MASP-1/3 in Complement Activation
The Role of MASP-1/3 in Complement Activation
Sekine, Hideharu; Takahashi, Minoru; Iwaki, Daisuke; Fujita, Teizo
mice (M1/3 KO) and furthermore backcrossed ...
... in breast cancer [142], and frequent  homozygous 
The Role of MicroRNA in Head and Neck Cancer
The Role of MicroRNA in Head and Neck Cancer
Mahjabeen, Ishrat; Jin, Yi; Chen, Dan; Wang, Anxun; Kolokythas, Antonia; Zhou, Xiaofeng
deletion of miR-31 gene was reported in ...
... F1 hybrid animals, due to the lessening of  homozygous 
A High Omega-3 Fatty Acid Diet has Different Effects on Early and Late Stage Myeloid Progenitors
A High Omega-3 Fatty Acid Diet has Different Effects on Early and Late Stage Myeloid Progenitors
Varney, Melinda E.; Buchanan, James T.; Dementieva, Yulia; Elaine Hardman, W.; Sollars, Vincent E.
recessive mutations in hybrid animals. ...
... present in the population studied. The  homozygous 
Protamine Alterations in Human Spermatozoa
Protamine Alterations in Human Spermatozoa
Jodar, Meritxell; Oliva, Rafael
subjects with the most abundant haplotype ...
... with a high risk of recurrence (65 %);  homozygous 
Assessment of the Potential Transplant Recipient
Assessment of the Potential Transplant Recipient
Power, Albert; Dupont, Peter J.
or complex heterozygous have much lesser ...
... should have lower parasite loads than  homozygous 
The functional importance of sequence versus expression variability of MHC alleles in parasite resistance
The functional importance of sequence versus expression variability of MHC alleles in parasite resistance
Axtner, Jan; Sommer, Simone
ones or should show differences in their ...
... drop outs and short allele dominance), and  homozygous 
Population genetics of Glossina palpalis palpalis from central African sleeping sickness foci
Population genetics of Glossina palpalis palpalis from central African sleeping sickness foci
Melachio, Trésor Tito Tanekou/TT; Simo, Gustave; Ravel, Sophie; De Meeûs, Thierry; Causse, Sandrine; Solano, Philippe; Lutumba, Pascal; Asonganyi, Tazoacha; Njiokou, Flobert
for the allele present for other analyses ...
... a lack of polymorphic markers in a highly  homozygous 
An integrated SSR map of grapevine based on five mapping populations
An integrated SSR map of grapevine based on five mapping populations
Doligez, A.; Adam-Blondon, A. F.; Cipriani, G.; Di Gaspero, G.; Laucou, V.; Merdinoglu, D.; Meredith, C. P.; Riaz, S.; Roux, C.; This, P.
region or alternatively a local increase ...
... formation in 1–2 % of stone formers. The  homozygous 
Biochemical Risk Evaluation in Patients with Urolithiasis
Biochemical Risk Evaluation in Patients with Urolithiasis
Tiselius, Hans-Göran
form is necessary for cystine ...
... in which Notch signaling is disrupted (  homozygous 
Notch Signaling in Pancreatic Morphogenesis and Pancreatic Cancer Pathogenesis
Notch Signaling in Pancreatic Morphogenesis and Pancreatic Cancer Pathogenesis
Lomberk, Gwen; Urrutia, Raul
mindbomb mutations) [36]. ...
... but are highly deleterious or lethal when  homozygous 
Male reproductive development: gene expression profiling of maize anther and pollen ontogeny
Male reproductive development: gene expression profiling of maize anther and pollen ontogeny
Ma, Jiong; Skibbe, David S; Fernandes, John; Walbot, Virginia
. ...
... with single bands were assumed to be  homozygous 
Evaluation of Genetic Diversity in Chinese Wild Apple Species Along with Apple Cultivars Using SSR Markers
Evaluation of Genetic Diversity in Chinese Wild Apple Species Along with Apple Cultivars Using SSR Markers
Zhang, Qiong; Li, Jing; Zhao, Yongbo; Korban, Schuyler S.; Han, Yuepeng
. ...
... III trials in patients with either heFH or  homozygous 
Current Treatment of Dyslipidemia: Evolving Roles of Non-Statin and Newer Drugs
Current Treatment of Dyslipidemia: Evolving Roles of Non-Statin and Newer Drugs
Kones, Richard; Rumana, Umme
FH (hoFH) produced comparable changes in ...
... for COPD compared with carriers with each  homozygous 
SLC11A1 Polymorphisms Are Associated with the Risk of Chronic Obstructive Pulmonary Disease in a Korean Population
SLC11A1 Polymorphisms Are Associated with the Risk of Chronic Obstructive Pulmonary Disease in a Korean Population
Kim, Eun Jin; Kim, Kyung Mee; Park, Sun Ha; Kim, Jong Sik; Lee, Won Kee; Cha, Sung Ick; Kim, Chang Ho; Kang, Young Mo; Han, Sung Beom; Jung, Tae Hoon; Park, Jae Yong
wild-type allele [adjusted odds ratio ...
... shaped teeth. This condition is caused by  homozygous 
Fibroblast growth factor signaling in mammalian tooth development
Fibroblast growth factor signaling in mammalian tooth development
Li, Chun-Ying; Prochazka, Jan; Goodwin, Alice F.; Klein, Ophir D.
or compound heterozygous mutations in FGF3 ...
... process. Materials and methods Mice  Homozygous 
Bone marrow-derived mesenchymal cells and MMP13 contribute to experimental choroidal neovascularization
Bone marrow-derived mesenchymal cells and MMP13 contribute to experimental choroidal neovascularization
Lecomte, Julie; Louis, Krystel; Detry, Benoit; Blacher, Silvia; Lambert, Vincent; Bekaert, Sandrine; Munaut, Carine; Paupert, Jenny; Blaise, Pierre; Foidart, Jean-Michel; Rakic, Jean-Marie; Krane, Stephen M.; Noel, Agnès
Mmp13-deficient mice (Mmp13 −/−) and the ...
... PI(3)P, PI(3,4)P2 and PI(3,4,5)P3 [21].  Homozygous 
Protein Profiling of the Dimorphic Pathogenic Fungus, Sporothrix schenckii
Protein Profiling of the Dimorphic Pathogenic Fungus, Sporothrix schenckii
Zhang, Zhenying; Hou, Binbin; Xin, Yi; Liu, Xiaoming
deletion of CaVps34p, a PI 3-kinase gene ...
... 2000). Thus, individuals who have a  homozygous 
Influence of glutathione-related genes on symptoms and immunologic markers among vulcanization workers in the southern Sweden rubber industries
Influence of glutathione-related genes on symptoms and immunologic markers among vulcanization workers in the southern Sweden rubber industries
Jönsson, Lena S.; Jönsson, Bo A. G.; Axmon, Anna; Littorin, Margareta; Broberg, Karin
deletion have no enzymatic activity. ...
... transgenic mice were unable to generate  homozygous 
Reproductive abnormalities in mice expressing omega-3 fatty acid desaturase in their mammary glands
Reproductive abnormalities in mice expressing omega-3 fatty acid desaturase in their mammary glands
Pohlmeier, William E.; Hovey, Russell C.; Eenennaam, Alison L.
offspring. ...
... makes it possible to identify specific  homozygous 
SNP Genotyping Technologies
SNP Genotyping Technologies
Studer, Bruno; Kölliker, Roland
and heterozygous alleles (Nazar and Robb ...
... used in Brassica species to produce  homozygous 
Microspore culture preferentially selects unreduced (2n) gametes from an interspecific hybrid of Brassica napus L. × Brassica carinata Braun
Microspore culture preferentially selects unreduced (2n) gametes from an interspecific hybrid of Brassica napus L. × Brassica carinata Braun
Nelson, Matthew N.; Mason, Annaliese S.; Castello, Marie-Claire; Thomson, Linda; Yan, Guijun; Cowling, Wallace A.
doubled haploid lines for breeding and ...
... (FEC) value with higher values observed in  homozygous 
The importance of immune gene variability (MHC) in evolutionary ecology and conservation
The importance of immune gene variability (MHC) in evolutionary ecology and conservation
Sommer, Simone
individuals. ...