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... the molecular genotype is known. Patients  homozygous 
Disorders of Leucine, Isoleucine, and Valine Metabolism
Disorders of Leucine, Isoleucine, and Valine Metabolism
Knerr, Ina; Vockley, Jerry; Gibson, K. Michael
for the Y393N Mennonite mutation are not ...
... experiments were conducted using stable,  homozygous 
Overexpression of AtFRO6 in transgenic tobacco enhances ferric chelate reductase activity in leaves and increases tolerance to iron-deficiency chlorosis
Overexpression of AtFRO6 in transgenic tobacco enhances ferric chelate reductase activity in leaves and increases tolerance to iron-deficiency chlorosis
Li, Li-Ya; Cai, Qiu-Yi; Yu, Dian-Si; Guo, Chang-Hong
T3 generation transformants, and wild-type ...
... all of which were carried either in a  homozygous 
Thiamine transporter-2 deficiency: outcome and treatment monitoring
Thiamine transporter-2 deficiency: outcome and treatment monitoring
Ortigoza-Escobar, Juan Darío; Serrano, Mercedes; Molero, Marta; Oyarzabal, Alfonso; Rebollo, Mónica; Muchart, Jordi; Artuch, Rafael; Rodríguez-Pombo, Pilar; Pérez-Dueñas, Belén
or heterozygous fashion [11, 19]. ...
... The individuals were found to be  homozygous 
Many LINE1 elements contribute to the transcriptome of human somatic cells
Many LINE1 elements contribute to the transcriptome of human somatic cells
Rangwala, Sanjida H; Zhang, Lili; Kazazian, Haig H, Jr
for the insertion unless otherwise noted ...
... RT PCR analyses of RNA extracted from  homozygous 
Mutation in Wilted Dwarf and Lethal 1 (WDL1) causes abnormal cuticle formation and rapid water loss in rice
Mutation in Wilted Dwarf and Lethal 1 (WDL1) causes abnormal cuticle formation and rapid water loss in rice
Park, Jong-Jin; Jin, Ping; Yoon, Jinmi; Yang, Jung-Il; Jeong, Hee Joong; Ranathunge, Kosala; Schreiber, Lukas; Franke, Rochus; Lee, In-Jung; An, Gynheung
mutant plants indicated that those three ...
... the combination of P{w + ; east + }/+ with  homozygous 
EAST affects the activity of Su(Hw) insulators by two different mechanisms in Drosophila melanogaster
EAST affects the activity of Su(Hw) insulators by two different mechanisms in Drosophila melanogaster
Melnikova, Larisa; Shapovalov, Igor; Kostyuchenko, Margarita; Georgiev, Pavel; Golovnin, Anton
mod(mdg4) u1 or mod(mdg4) T6 mutation ...
... mutations, focal amplifications and  homozygous 
Pathobiology of Hepatitis B Virus-Induced Carcinogenesis
Pathobiology of Hepatitis B Virus-Induced Carcinogenesis
Guerrieri, Francesca; Belloni, Laura; Pediconi, Natalia; Levrero, Massimo
deletions, 161 putative driver genes ...
... to many generations before they appear in  homozygous 
Sterile Insect Technique
Sterile Insect Technique
Klassen, Waldemar
form required for expression. ...
... (heterozygous mutation) and recessive (  homozygous 
Diagnostic Procedures
Diagnostic Procedures
Touati, Guy; Mochel, Fanny; Rabier, Daniel
or compound heterozygous mutations) ...
... β-thalassemia[25] Generation of iPSCs from  homozygous 
Progress and Promise Towards Safe Induced Pluripotent Stem Cells for Therapy
Progress and Promise Towards Safe Induced Pluripotent Stem Cells for Therapy
Seifinejad, Ali; Tabebordbar, Mohammadsharif; Baharvand, Hossein; Boyer, Laurie A.; Hosseini Salekdeh, Ghasem
β-thalassemia and differentiating of them ...
... Nf1 loxP/loxP; p53 –/–) mice with  homozygous 
Pten-Deficient Mouse Models for High-Grade Astrocytomas
Pten-Deficient Mouse Models for High-Grade Astrocytomas
Kwon, Chang Hyuk
deletion and Mut3 (hGFAP-cre; Nf1 loxP/+; ...
... as putatively X-linked because they were  homozygous 
Transcriptome of the dead: characterisation of immune genes and marker development from necropsy samples in a free-ranging marine mammal
Transcriptome of the dead: characterisation of immune genes and marker development from necropsy samples in a free-ranging marine mammal
Hoffman, Joseph I; Thorne, Michael AS; Trathan, Philip N; Forcada, Jaume
in 84 males but carried the expected ...
... Now, to advance F2 generation plants to  homozygous 
Quantitative Traits in Breeding
Quantitative Traits in Breeding
Silva, Felipe Lopes; Resende, Marcos Deon Vilela; Ludke, Willian Hytalo; Bueno, Thays Vieira
lines, one can perform early selection via ...
... allele/wild-type allele). Women with the  homozygous 
Cigarette smoking, cytochrome P4501A1 polymorphisms, and breast cancer among African-American and white women
Cigarette smoking, cytochrome P4501A1 polymorphisms, and breast cancer among African-American and white women
Li, Yu; Millikan, Robert C; Bell, Douglas A; Cui, Lisa; Tse, Chiu-Kit J; Newman, Beth; Conway, Kathleen
wild-type allele genotypes (wild-type ...
... a more recent analysis found that patients  homozygous 
Drug metabolism-related genes as potential biomarkers: analysis of expression in normal and tumour breast tissue
Drug metabolism-related genes as potential biomarkers: analysis of expression in normal and tumour breast tissue
Martinez, Vanesa; Kennedy, Susan; Doolan, Padraig; Gammell, Patrick; Joyce, Helena; Kenny, Elaine; Prakash Mehta, Jai; Ryan, Eoin; O’Connor, Robert; Crown, John; Clynes, Martin; O’Driscoll, Lorraine
for a GST A1 polymorphism that results in ...
... 36]. Approximately 50% of these Hox11L1/  homozygous 
Advances in understanding functional variations in the Hirschsprung disease spectrum (variant Hirschsprung disease)
Advances in understanding functional variations in the Hirschsprung disease spectrum (variant Hirschsprung disease)
Moore, S. W.
experimental animals developed functional ...
... (Becraft and Asuncion-Crabb 2000). In  homozygous 
The cereal starch endosperm development and its relationship with other endosperm tissues and embryo
The cereal starch endosperm development and its relationship with other endosperm tissues and embryo
Zheng, Yankun; Wang, Zhong
loss-of-function sal1 endosperm, several ...
... with increased ACE activity. The  homozygous 
Pathophysiology of Progressive Renal Disease
Pathophysiology of Progressive Renal Disease
Eddy, Allison
ACE D/D genotype has been associated with ...
... abnormalities in individuals with  homozygous 
Defective WNT signaling associates with bone marrow fibrosis—a cross-sectional cohort study in a family with WNT1 osteoporosis
Defective WNT signaling associates with bone marrow fibrosis—a cross-sectional cohort study in a family with WNT1 osteoporosis
Mäkitie, R. E.; Niinimäki, R.; Kakko, S.; Honkanen, T.; Kovanen, P. E.; Mäkitie, O.
WNT1 mutations. ...
... genotypes and at least three times for  homozygous 
Non-invasive conservation genetics of the critically endangered golden-crowned sifaka (Propithecus tattersalli): high diversity and significant genetic differentiation over a small range
Non-invasive conservation genetics of the critically endangered golden-crowned sifaka (Propithecus tattersalli): high diversity and significant genetic differentiation over a small range
Quéméré, Erwan; Louis, Edward E., Jr.; Ribéron, Alexandre; Chikhi, Lounès; Crouau-Roy, Brigitte
genotypes. ...
... (Leyva et al. 2007) in order to generate  homozygous 
Tobacco seeds as efficient production platform for a biologically active anti-HBsAg monoclonal antibody
Tobacco seeds as efficient production platform for a biologically active anti-HBsAg monoclonal antibody
Hernández-Velázquez, Abel; López-Quesada, Alina; Ceballo-Cámara, Yanaysi; Cabrera-Herrera, Gleysin; Tiel-González, Kenia; Mirabal-Ortega, Liliana; Pérez-Martínez, Marlene; Pérez-Castillo, Rosabel; Rosabal-Ayán, Yamilka; Ramos-González, Osmani; Enríquez-Obregón, Gil; Depicker, Ann; Pujol-Ferrer, Merardo
lines from the plants exhibiting the ...
... mild hypercalcaemia, NSHPT is caused by  homozygous 
Hereditary hyperparathyroidism—a consensus report of the European Society of Endocrine Surgeons (ESES)
Hereditary hyperparathyroidism—a consensus report of the European Society of Endocrine Surgeons (ESES)
Iacobone, Maurizio; Carnaille, Bruno; Palazzo, F. Fausto; Vriens, Menno
mutations. ...
... vector successfully and then several  homozygous 
Overexpression of Tomato Homolog of Glycolate/Glycerate Transporter Gene PLGG1/AtLrgB Leads to Reduced Chlorophyll Biosynthesis
Overexpression of Tomato Homolog of Glycolate/Glycerate Transporter Gene PLGG1/AtLrgB Leads to Reduced Chlorophyll Biosynthesis
Kang, Xia; Huang, Wei; Tang, Ning; Li, Zhengguo
tomato lines from independent ...
... +/− /pmel-1 F1 mice produced by crossing  homozygous 
Poly-ICLC promotes the infiltration of effector T cells into intracranial gliomas via induction of CXCL10 in IFN-α and IFN-γ dependent manners
Poly-ICLC promotes the infiltration of effector T cells into intracranial gliomas via induction of CXCL10 in IFN-α and IFN-γ dependent manners
Zhu, Xinmei; Fallert-Junecko, Beth A.; Fujita, Mitsugu; Ueda, Ryo; Kohanbash, Gary; Kastenhuber, Edward R.; McDonald, Heather A.; Liu, Yan; Kalinski, Pawel; Reinhart, Todd A.; Salazar, Andres M.; Okada, Hideho
female Pmel-1 and male IFN-γ −/− mice were ...
... methods Materials and DNA extraction The  homozygous 
Correction of the lack of commutability between plasmid DNA and genomic DNA for quantification of genetically modified organisms using pBSTopas as a model
Correction of the lack of commutability between plasmid DNA and genomic DNA for quantification of genetically modified organisms using pBSTopas as a model
Zhang, Li; Wu, Yuhua; Wu, Gang; Cao, Yinglong; Lu, Changming
CRM GM Topas 19/2 (AOCS 0711-D) and ...