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... converted into 5′AMP by PDE. AC: Adenylate  cyclase 
The Molecules That Transmit Information into the Cell: The Intracellular Signaling Pathways
The Molecules That Transmit Information into the Cell: The Intracellular Signaling Pathways
Chedrese, Pedro J.; Bertorello, Alejandro M.
; 5′AMP: 5′ adenosine monophosphate; ATP: ...
... 1,2 DAG - 1,2 diacylglycerol, AC - adenylate  cyclase 
Cardiovascular Drug Therapy
Cardiovascular Drug Therapy
Maffei, Frank A.
, cAMP – cyclic adenosine monophosphate ...
... couple to Gαs, which activates adenylate  cyclase 
Dopamine Receptor Signaling: Intracellular Pathways to Behavior
Dopamine Receptor Signaling: Intracellular Pathways to Behavior
Romanelli, Robert J.; Williams, John T.; Neve, Kim A.
[16, 17]; however, recent evidence suggests ...
... downstream effec tors, namely, adenylyl  cyclase 
Methods for the Detection of Altered β-Adrenergic Receptor Signaling Pathways in Hypertrophied Hearts
Methods for the Detection of Altered β-Adrenergic Receptor Signaling Pathways in Hypertrophied Hearts
J. Wolf, Matthew; Tachibana, Hideo; A. Rockman, Howard
. ...
... transduction systems including adenylyl  cyclase 
Modulation of Gi Protein Expression in Hypertension: Molecular Mechanisms
Modulation of Gi Protein Expression in Hypertension: Molecular Mechanisms
Anand-Srivastava, Madhu B.
–cAMP and phospholipase C ...
... receptor systems, such as guanylyl  cyclase 
Cardiac and Vascular Receptors and Signal Transduction
Cardiac and Vascular Receptors and Signal Transduction
Sigg, Daniel C.; Hezi-Yamit, Ayala
-related receptors (e.g., receptors for ...
... (cGMP), via activation of soluble guanylate  cyclase 
Platelet Hyperaggregability: Impaired Responsiveness to Nitric Oxide (“Platelet NO Resistance”) as a Therapeutic Target
Platelet Hyperaggregability: Impaired Responsiveness to Nitric Oxide (“Platelet NO Resistance”) as a Therapeutic Target
Rajendran, Sharmalar; Chirkov, Yuliy Y.
, is the principal mechanism of negative ...
... transduction systems including adenylyl  cyclase 
Role of Gi Proteins in Hypertension
Role of Gi Proteins in Hypertension
Li, Yuan; Anand-Srivastava, Madhu B.
/cAMP and phospholipase C ...
... Adenosine-induced vasorelaxation via adenylyl  cyclase 
Clopidogrel improves endothelial function and NO bioavailability by sensitizing adenylyl cyclase in rats with congestive heart failure
Clopidogrel improves endothelial function and NO bioavailability by sensitizing adenylyl cyclase in rats with congestive heart failure
Schäfer, Andreas; Fraccarollo, Daniela; Pförtsch, Stephanie; Loch, Elena; Neuser, Jonas; Vogt, Christian; Bauersachs, Johann
stimulation was attenuated in CHF and ...
... both D1- and D2-like receptors. ADP-ribosyl  cyclase 
Cyclic ADP-ribose as an endogenous inhibitor of the mTOR pathway downstream of dopamine receptors in the mouse striatum
Cyclic ADP-ribose as an endogenous inhibitor of the mTOR pathway downstream of dopamine receptors in the mouse striatum
Higashida, Haruhiro; Kamimura, Shin-ya; Inoue, Takeshi; Hori, Osamu; Islam, Mohammad Saharul; Lopatina, Olga; Tsuji, Chiharu
activity increased significantly during ...
... that intrathecal injection of an adenylate  cyclase 
Adenylate cyclase inhibition attenuates neuropathic pain but lacks pre-emptive effects in rats
Adenylate cyclase inhibition attenuates neuropathic pain but lacks pre-emptive effects in rats
Liou, Jiin-Tarng; Liu, Fu-Chao; Mao, Chih-Chieh; Hsin, Shi-Tai; Lui, Ping-Wing
inhibitor attenuated tactile allodynia caused ...
... of TSH receptors, levels of adenylate  cyclase 
Biological characteristics of adenomatous nodules, adenomas, and hyperfunctioning nodules as defined by adenylate cyclase activity and TSH receptors
Biological characteristics of adenomatous nodules, adenomas, and hyperfunctioning nodules as defined by adenylate cyclase activity and TSH receptors
Thomas, C. G., Jr.; Combest, W.; McQuade, R.; Jordan, H.; Reddick, R.; Nayfeh, S. N.
, and the responsiveness of adenylate ...
... from endothelium. NO· activates guanylate  cyclase 
Oxyradicals as a Mechanism of Acetylcholine-induced Vascular Relaxation
Oxyradicals as a Mechanism of Acetylcholine-induced Vascular Relaxation
Prasad, Kailash
which converts guanosine triphosphate to ...
... Methods Cyclic AMP production, adenylyl  cyclase 
Altered collecting duct adenylyl cyclase content in collecting duct endothelin-1 knockout mice
Altered collecting duct adenylyl cyclase content in collecting duct endothelin-1 knockout mice
Strait, Kevin A; Stricklett, Peter K; Kohan, Donald E
(AC) mRNA, and AC protein were measured in ...
... thyroid neoplasms have a greater adenylate  cyclase 
Adenylate cyclase activity as a predictor of thyroid tumor aggressiveness
Adenylate cyclase activity as a predictor of thyroid tumor aggressiveness
Siperstein, Allan E.; Zeng, Qui -Hua; Gum, Elizabeth T.; Levin, Kenneth E.; Clark, Orlo H.
activity in response to thyroid stimulating ...
... O(ms) [Ca2+]i, NO O(s) IP3 O(10 s) Adenylate  cyclase 
Mechanotransduction and Vascular Resistance
Mechanotransduction and Vascular Resistance
Thiriet, Marc
, PGi2, PGf2 O(mn) PDGF, endothelin, tPA, ...
... monooxygenase (PAM) PAM 5. the glutaminyl  cyclase 
Vertebrate Protein and Peptide Hormones
Vertebrate Protein and Peptide Hormones
Kleine, Bernhard; Rossmanith, Winfried G.
glutaminyl ...
... the abundance of a calcium-sensitive adenylyl  cyclase 
Adenylyl cyclase 8 is central to glucagon-like peptide 1 signalling and effects of chronically elevated glucose in rat and human pancreatic beta cells
Adenylyl cyclase 8 is central to glucagon-like peptide 1 signalling and effects of chronically elevated glucose in rat and human pancreatic beta cells
Roger, B.; Papin, J.; Vacher, P.; Raoux, M.; Mulot, A.; Dubois, M.; Kerr-Conte, J.; Voy, B. H.; Pattou, F.; Charpentier, G.; Jonas, J.-C.; Moustaïd-Moussa, N.; Lang, J.
(ADCY8) and GLP-1 receptor (GLP1R). ...
... cell function(s), such as guanylyl  cyclase 
Signaling in the Endothelium
Signaling in the Endothelium
Marín-García, José
, mitochondrial iron–sulfur cluster enzymes, ...
... phosphodiesterases or changes in adenylate  cyclase 
Iloprost-induced desensitization of the prostacyclin receptor in isolated rabbit lungs
Iloprost-induced desensitization of the prostacyclin receptor in isolated rabbit lungs
Schermuly, Ralph T; Pullamsetti, Soni S; Breitenbach, Susanne C; Weissmann, Norbert; Ghofrani, Hossein A; Grimminger, Friedrich; Nilius, Sigrid M; Schrör, Karsten; Meger-Kirchrath, Jutta; Seeger, Werner; Rose, Frank
activity, as suggested by unaltered ...
... morphine acts via inhibition of adenylate  cyclase 
The μ opioid agonist morphine modulates potentiation of capsaicin-evoked TRPV1 responses through a cyclic AMP-dependent protein kinase A pathway
The μ opioid agonist morphine modulates potentiation of capsaicin-evoked TRPV1 responses through a cyclic AMP-dependent protein kinase A pathway
Vetter, Irina; Wyse, Bruce D; Monteith, Gregory R; Roberts-Thomson, Sarah J; Cabot, Peter J
to inhibit PKA-potentiated TRPV1 responses. ...
... O(ms) [Ca2+]i, NO O(s) IP3 O(10 s) Adenylate  cyclase 
Mechanotransduction and Vascular Resistance
Mechanotransduction and Vascular Resistance
Thiriet, Marc
, PGi2, PGf2 O(mn) PDGF, endothelin, tPA, ...
... cAMP synthesis due to uncoupling of adenylyl  cyclase 
Myocardial Phosphodiesterases and Regulation of Cardiac Contractility in Health and Cardiac Disease
Myocardial Phosphodiesterases and Regulation of Cardiac Contractility in Health and Cardiac Disease
Osadchii, Oleg E.
from β-adrenoreceptor. ...
... O(ms) [Ca2+]i, NO O(s) IP3 O(10 s) Adenylate  cyclase 
Mechanotransduction and Vascular Resistance
Mechanotransduction and Vascular Resistance
Thiriet, Marc
, PGi2, PGf2 O(mn) PDGF, endithelin, tPA, ...
... through activation of soluble guanylate  cyclase 
Selective Pulmonary Vasodilators
Selective Pulmonary Vasodilators
Beghetti, Maurice; Steinhorn, Robin H.
, which promotes conversion of GTP to cGMP ...