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... catalyzing cADPR formation, ADP-ribosyl  cyclase 
Selective inhibitors of cardiac ADPR cyclase as novel anti-arrhythmic compounds
Selective inhibitors of cardiac ADPR cyclase as novel anti-arrhythmic compounds
Kannt, Aimo; Sicka, Kerstin; Kroll, Katja; Kadereit, Dieter; Gögelein, Heinz
(ADPRC), was first purified from Aplysia ...
... been cloned and characterized: the adenylate  cyclase 
cAMP signaling in Aspergillus fumigatus is involved in the regulation of the virulence gene pksP and in defense against killing by macrophages
cAMP signaling in Aspergillus fumigatus is involved in the regulation of the virulence gene pksP and in defense against killing by macrophages
Liebmann, B.; Gattung, S.; Jahn, B.; Brakhage, A. A.
gene acyA, and gpaA and gpaB, both of which ...
... enzymes are required, ε- and β-lycopene  cyclase 
A novel type of lycopene ε-cyclase in the marine cyanobacterium Prochlorococcus marinus MED4
A novel type of lycopene ε-cyclase in the marine cyanobacterium Prochlorococcus marinus MED4
Stickforth, Per; Steiger, Sabine; Hess, Wolfgang R.; Sandmann, Gerhard
. ...
... the GAF domain in the cyanobacterial adenylyl  cyclase 
The GAF-Tandem Domain of Phosphodiesterase 5 as a Potential Drug Target
The GAF-Tandem Domain of Phosphodiesterase 5 as a Potential Drug Target
Schultz, Joachim E.; Dunkern, Torsten; Gawlitta-Gorka, Elvira; Sorg, Gabriele
CyaB1. ...
... extent than in wild type cells. Adenylyl  cyclase 
A novel Dictyostelium RasGEF required for chemotaxis and development
A novel Dictyostelium RasGEF required for chemotaxis and development
Arigoni, Maddalena; Bracco, Enrico; Lusche, Daniel F; Kae, Helmut; Weeks, Gerald; Bozzaro, Salvatore
activation in response to cAMP pulses is ...
... works through activation of soluble guanylyl  cyclase 
Soluble Guanylyl Cyclase: The Nitric Oxide Receptor
Soluble Guanylyl Cyclase: The Nitric Oxide Receptor
Koesling, Doris; Sitaramayya, Ari
and elevation of cyclic GMP concentration. ...
... we analyzed the β-receptor-mediated adenylyl  cyclase 
Comparative pharmacology of human β-adrenergic receptor subtypes—characterization of stably transfected receptors in CHO cells
Comparative pharmacology of human β-adrenergic receptor subtypes—characterization of stably transfected receptors in CHO cells
Hoffmann, C.; Leitz, M. R.; Oberdorf-Maass, S.; Lohse, M. J.; Klotz, K.-N.
activity in isolated membranes from these ...
... with activation-independent monoterpenoid  cyclase 
Prokaryotic squalene-hopene cyclases can be converted to citronellal cyclases by single amino acid exchange
Prokaryotic squalene-hopene cyclases can be converted to citronellal cyclases by single amino acid exchange
Siedenburg, Gabriele; Breuer, Michael; Jendrossek, Dieter
activity. ...
... Adenosine-induced vasorelaxation via adenylyl  cyclase 
Clopidogrel improves endothelial function and NO bioavailability by sensitizing adenylyl cyclase in rats with congestive heart failure
Clopidogrel improves endothelial function and NO bioavailability by sensitizing adenylyl cyclase in rats with congestive heart failure
Schäfer, Andreas; Fraccarollo, Daniela; Pförtsch, Stephanie; Loch, Elena; Neuser, Jonas; Vogt, Christian; Bauersachs, Johann
stimulation was attenuated in CHF and ...
... β2-adrenergic receptor activates adenylate  cyclase 
Cardiovascular activity1
Cardiovascular activity1
Vogel, H. Gerhard; Vogel, Wolfgang H.; Schölkens, Bernward A.; Sandow, Jürgen; Müller, Günter; Vogel, Wolfgang F.
resulting in an increase in the cyclic AMP ...
... natriuretic peptide (ANP) sensitive guanylyl  cyclase 
Particulate ANP-sensitive guanylyl cyclase: induction in cultured human peripheral CD3+ mononuclear blood cells
Particulate ANP-sensitive guanylyl cyclase: induction in cultured human peripheral CD3+ mononuclear blood cells
Heim, J.-M.; Knau, B.; Sturm, C.; Fricke, H.; Hartmann, J.; Pachmann, K.; Schmidt, K.-N.; Vollmar, A.; Gerzer, R.
in the immune system. ...
... the bacterium Beggiatoa sp. and shows low  cyclase 
A Fluorometric Activity Assay for Light-Regulated Cyclic-Nucleotide-Monophosphate Actuators
A Fluorometric Activity Assay for Light-Regulated Cyclic-Nucleotide-Monophosphate Actuators
Schumacher, Charlotte Helene; Körschen, Heinz G.; Nicol, Christopher; Gasser, Carlos; Seifert, Reinhard; Schwärzel, Martin; Möglich, Andreas
activity in darkness that can be enhanced by ...
... neuronal function of one receptor guanylyl  cyclase 
Receptor guanylyl cyclases in mammalian olfactory function
Receptor guanylyl cyclases in mammalian olfactory function
Zufall, Frank; Munger, Steven D.
, GC-D. ...
... of these compounds, whereas adenylyl  cyclase 
Cytotoxic purine nucleoside analogues bind to A1, A2A, and A3 adenosine receptors
Cytotoxic purine nucleoside analogues bind to A1, A2A, and A3 adenosine receptors
Jensen, Kyle; Johnson, L’Aurelle A.; Jacobson, Pamala A.; Kachler, Sonja; Kirstein, Mark N.; Lamba, Jatinder; Klotz, Karl-Norbert
activity was used to assess the binding to ...
... war log-normal verteilt. Nur die Adenylat-  Cyclase 
Adenylate cyclase in human gastric mucosa: its activation by histamine in morphologically different biopsy specimens
Adenylate cyclase in human gastric mucosa: its activation by histamine in morphologically different biopsy specimens
Ruoff, H. -J.; Painz, B.; Becker, M.; Rack, M.; Sewing, K. -Fr; Malchow, H.
der Fundusschleimhaut, nicht dagegen die der ...
... G-protein linked adenylyl  cyclase 
Ectopic expression of cyclase associated protein CAP restores the streaming and aggregation defects of adenylyl cyclase a deficient Dictyostelium discoideumcells
Ectopic expression of cyclase associated protein CAP restores the streaming and aggregation defects of adenylyl cyclase a deficient Dictyostelium discoideumcells
Sultana, Hameeda; Neelakanta, Girish; Rivero, Francisco; Blau-Wasser, Rosemarie; Schleicher, Michael; Noegel, Angelika A
pathways are crucially involved and a mutant ...
... of a photoreceptor with that of an adenylyl  cyclase 
Photoactivatable Adenylyl Cyclases (PACs) as a Tool to Study cAMP Signaling In Vivo: An Overview
Photoactivatable Adenylyl Cyclases (PACs) as a Tool to Study cAMP Signaling In Vivo: An Overview
Efetova, Marina; Schwärzel, Martin
. ...
... of the β-adrenergic-receptor-linked adenylyl  cyclase 
Receptor-independent sensitization of the adenylyl cylase after chronic treatment with cyclosporine A
Receptor-independent sensitization of the adenylyl cylase after chronic treatment with cyclosporine A
Simonis, G.; Christ, T.; Bährle, S. K.; Pena, M.; Schoen, S. P.; Marquetant, R.; Ravens, U.; Strasser, R. H.
(AC) system contributes to hypertension is ...
... the platelet, subsequently inhibits adenylyl  cyclase 
Time-resolved in silico modeling of fine-tuned cAMP signaling in platelets: feedback loops, titrated phosphorylations and pharmacological modulation
Time-resolved in silico modeling of fine-tuned cAMP signaling in platelets: feedback loops, titrated phosphorylations and pharmacological modulation
Wangorsch, Gaby; Butt, Elke; Mark, Regina; Hubertus, Katharina; Geiger, Jörg; Dandekar, Thomas; Dittrich, Marcus
(AC) but as well activates PDE3. ...
... from 96 subjects were assayed for adenylate  cyclase 
Human gastric mucosal adenylate cyclase: Activation by histamine-H2-receptor stimulation and inhibition by cimetidine in vitro and in peptic ulcer patients
Human gastric mucosal adenylate cyclase: Activation by histamine-H2-receptor stimulation and inhibition by cimetidine in vitro and in peptic ulcer patients
Ruoff, H. -J.; Becker, M.; Painz, B.; Rack, M.; Sewing, K. -Fr.; Malchow, H.
activity to characterize specificity of the ...
... fluoride- and isoproterenol-stimulated adenyl  cyclase 
Occurrence of adenyl cyclase activity in human erythrocytes
Occurrence of adenyl cyclase activity in human erythrocytes
Kaiser, Götz; Quiring, Klaus; Gauger, Dietrich; Palm, Dieter; Becker, Hansjörg; Schoeppe, Wilhelm
activities; it was investigated whether ...
... EAL domain of STM1703, solely, diguanylate  cyclase 
Detailed analysis of c-di-GMP mediated regulation of csgD expression in Salmonella typhimurium
Detailed analysis of c-di-GMP mediated regulation of csgD expression in Salmonella typhimurium
Ahmad, Irfan; Cimdins, Annika; Beske, Timo; Römling, Ute
and phosphodiesterase activities are required ...
... Since the effect of VILIP-1 on adenylyl  cyclase 
Visinin-like proteins (VSNLs): interaction partners and emerging functions in signal transduction of a subfamily of neuronal Ca2+-sensor proteins
Visinin-like proteins (VSNLs): interaction partners and emerging functions in signal transduction of a subfamily of neuronal Ca2+-sensor proteins
Braunewell, Karl-Heinz; Szanto, Andres J. Klein
was not observed in other neural cell lines ...
... activation’, consisting of four adenylate  cyclase 
High throughput synthetic lethality screen reveals a tumorigenic role of adenylate cyclase in fumarate hydratase-deficient cancer cells
High throughput synthetic lethality screen reveals a tumorigenic role of adenylate cyclase in fumarate hydratase-deficient cancer cells
Boettcher, Michael; Lawson, Andrew; Ladenburger, Viola; Fredebohm, Johannes; Wolf, Jonas; Hoheisel, Jörg D; Frezza, Christian; Shlomi, Tomer
genes ADCY3, ADCY6, ADCY7 and ADCY9 (out of a ...
... phosphodiesterases or changes in adenylate  cyclase 
Iloprost-induced desensitization of the prostacyclin receptor in isolated rabbit lungs
Iloprost-induced desensitization of the prostacyclin receptor in isolated rabbit lungs
Schermuly, Ralph T; Pullamsetti, Soni S; Breitenbach, Susanne C; Weissmann, Norbert; Ghofrani, Hossein A; Grimminger, Friedrich; Nilius, Sigrid M; Schrör, Karsten; Meger-Kirchrath, Jutta; Seeger, Werner; Rose, Frank
activity, as suggested by unaltered ...