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... USA The nitric oxide (NO)-soluble guanylate  cyclase 
Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications
Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications
Todd Milne, G.; Sandner, Peter; Lincoln, Kathleen A.; Harrison, Paul C.; Chen, Hongxing; Wang, Hong; Clifford, Holly; Qian, Hu Sheng; Wong, Diane; Sarko, Chris; Fryer, Ryan; Richman, Jeremy; Reinhart, Glenn A.; Boustany, Carine M.; Pullen, Steven S.; Andresen, Henriette; Moltzau, Lise Román; Cataliotti, Alessandro; Levy, Finn Olav; Lukowski, Robert; Frankenreiter, Sandra; Friebe, Andreas; Calamaras, Timothy; Baumgartner, Robert; McLaughlin, Angela; Aronovitz, Mark; Baur, Wendy; Wang, Guang-Rong; Kapur, Navin; Karas, Richard; Blanton, Robert; Hell, Stefan; Waldman, Scott A.; Lin, Jieru E.; Colon-Gonzalez, Francheska; Kim, Gilbert W.; Blomain, Erik S.; Merlino, Dante; Snook, Adam; Erdmann, Jeanette; Wobst, Jana; Kessler, Thorsten; Schunkert, Heribert; Walter, Ulrich; Pagel, Oliver; Walter, Elena; Gambaryan, Stepan; Smolenski, Albert; Jurk, Kerstin; Zahedi, Rene; Klinger, James R.; Benza, Raymond L.; Corris, Paul A.; Langleben, David; Naeije, Robert; Simonneau, Gérald; Meier, Christian; Colorado, Pablo; Chang, Mi Kyung; Busse, Dennis; Hoeper, Marius M.; Masferrer, Jaime L.; Jacobson, Sarah; Liu, Guang; Sarno, Renee; Bernier, Sylvie; Zhang, Ping; Todd Milne, G.; Flores-Costa, Roger; Currie, Mark; Hall, Katherine; Möhrle, Dorit; Reimann, Katrin; Wolter, Steffen; Wolters, Markus; Mergia, Evanthia; Eichert, Nicole; Geisler, Hyun-Soon; Ruth, Peter; Friebe, Andreas; Feil, Robert; Zimmermann, Ulrike; Koesling, Doris; Knipper, Marlies; Rüttiger, Lukas; Tanaka, Yasutake; Okamoto, Atsuko; Nojiri, Takashi; Kumazoe, Motofumi; Tokudome, Takeshi; Miura, Koichi; Hino, Jun; Hosoda, Hiroshi; Miyazato, Mikiya; Kangawa, Kenji; Kapil, Vikas; Ahluwalia, Amrita; Paolocci, Nazareno; Eaton, Philip; Campbell, James C.; Henning, Philipp; Franz, Eugen; Sankaran, Banumathi; Herberg, Friedrich W.; Kim, Choel; Wittwer, M.; Luo, Q.; Kaila, V.; Dames, S. A.; Tobin, Andrew; Alam, Mahmood; Rudyk, Olena; Krasemann, Susanne; Hartmann, Kristin; Prysyazhna, Oleksandra; Zhang, Min; Zhao, Lan; Weiss, Astrid; Schermuly, Ralph; Eaton, Philip; Moyes, Amie J.; Chu, Sandy M.; Baliga, Reshma S.; Hobbs, Adrian J.; Michalakis, Stylianos; Mühlfriedel, Regine; Schön, Christian; Fischer, Dominik M.; Wilhelm, Barbara; Zobor, Ditta; Kohl, Susanne; Peters, Tobias; Zrenner, Eberhart; Bartz-Schmidt, Karl Ulrich; Ueffing, Marius; Wissinger, Bernd; Seeliger, Mathias; Biel, Martin; Ranek, Mark J.; Kokkonen, Kristen M.; Lee, Dong I.; Holewinski, Ronald J.; Agrawal, Vineet; Virus, Cornelia; Stevens, Donté A.; Sasaki, Masayuki; Zhang, Huaqun; Mannion, Mathew M.; Rainer, Peter P.; Page, Richard C.; Schisler, Jonathan C.; Van Eyk, Jennifer E.; Willis, Monte S.; Kass, David A.; Zaccolo, Manuela; Russwurm, Michael; Giesen, Jan; Russwurm, Corina; Füchtbauer, Ernst-Martin; Koesling, Doris; Bork, Nadja I.; Nikolaev, Viacheslav O.; Agulló, Luis; Floor, Martin; Villà-Freixa, Jordi; Manfra, Ornella; Calamera, Gaia; Surdo, Nicoletta C.; Meier, Silja; Froese, Alexander; Nikolaev, Viacheslav O.; Zaccolo, Manuela; Levy, Finn Olav; Andressen, Kjetil Wessel; Aue, Annemarie; Schwiering, Fabian; Groneberg, Dieter; Friebe, Andreas; Bajraktari, Gzona; Burhenne, Jürgen; Haefeli, Walter E.; Weiss, Johanna; Beck, Katharina; Voussen, Barbara; Vincent, Alexander; Parsons, Sean P.; Huizinga, Jan D.; Friebe, Andreas; Mónica, Fabiola Zakia; Seto, Edward; Murad, Ferid; Bian, Ka; Burgoyne, Joseph R.; Prysyazhna, Oleksandra; Richards, Daniel; Eaton, Philip; Calamera, Gaia; Bjørnerem, Marianne; Ulsund, Andrea Hembre; Kim, Jeong Joo; Kim, Choel; Levy, Finn Olav; Andressen, Kjetil Wessel; Donzelli, Sonia; Goetz, Mara; Schmidt, Kjestine; Wolters, Markus; Stathopoulou, Konstantina; Prysyazhna, Oleksandra; Scotcher, Jenna; Dees, Christian; Subramanian, Hariharan; Butt, Elke; Kamynina, Alisa; Bruce King, S.; Nikolaev, Viacheslav O.; de Witt, Cor; Leichert, Lars I.; Feil, Robert; Eaton, Philip; Cuello, Friederike; Dobrowinski, Hyazinth; Lehners, Moritz; Schmidt, Michael Paolillo Hannes; Feil, Robert; Feil, Susanne; Wen, Lai; Wolters, Markus; Thunemann, Martin; Schmidt, Kjestine; Olbrich, Marcus; Langer, Harald; Gawaz, Meinrad; Friebe, Andreas; de Wit, Cor; Feil, Robert; Franz, Eugen; Kim, Jeong Joo; Bertinetti, Daniela; Kim, Choel; Herberg, Friedrich W.; Ghofrani, Hossein-Ardeschir; Grimminger, Friedrich; Grünig, Ekkehard; Huang, Yigao; Jansa, Pavel; Jing, Zhi Cheng; Kilpatrick, David; Langleben, David; Rosenkranz, Stephan; Menezes, Flavia; Fritsch, Arno; Nikkho, Sylvia; Frey, Reiner; Humbert, Marc; Groneberg, Dieter; Aue, Annemarie; Schwiering, Fabian; Friebe, Andreas; Harloff, Manuela; Reinders, Joerg; Schlossmann, Jens; Jung, Joon; Wales, Jessica A.; Chen, Cheng-Yu; Breci, Linda; Weichsel, Andrzej; Bernier, Sylvie G.; Solinga, Robert; Sheppeck, James E., II; Renhowe, Paul A.; Montfort, William R.; Qin, Liying; Sung, Ying-Ju; Casteel, Darren; Kim, Choel; Kollau, Alexander; Neubauer, Andrea; Schrammel, Astrid; Russwurm, Michael; Koesling, Doris; Mayer, Bernd; Kumazoe, Motofumi; Takai, Mika; Takeuchi, Chieri; Kadomatsu, Mai; Hiroi, Shun; Takamatsu, Kanako; Nojiri, Takashi; Kangawa, Kenji; Tachibana, Hirofumi; Opelt, Marissa; Eroglu, Emrah; Waldeck-Weiermair, Markus; Russwurm, Michael; Koesling, Doris; Malli, Roland; Graier, Wolfgang F.; Fassett, John T.; Schrammel, Astrid; Mayer, Bernd; Sollie, Selene J.; Moltzau, Lise Román; Hernandez-Valladares, Maria; Berven, Frode; Levy, Finn Olav; Andressen, Kjetil W.; Nojiri, Takashi; Tokudome, Takeshi; Kumazoe, Motofumi; Arai, Miki; Suzuki, Yutaka; Miura, Koichi; Hino, Jun; Hosoda, Hiroshi; Miyazato, Mikiya; Okumura, Meinoshin; Kawaoka, Shinpei; Kangawa, Kenji; Peters, Stefanie; Schmidt, Hannes; Selin Kenet, B.; Nies, Sarah Helena; Frank, Katharina; Wen, Lai; Rathjen, Fritz G.; Feil, Robert; Petrova, Olga N.; Lamarre, Isabelle; Négrerie, Michel; Robinson, Jerid W.; Egbert, Jeremy R.; Davydova, Julia; Jaffe, Laurinda A.; Potter, Lincoln R.; Robinson, Jerid W.; Blixt, Nicholas; Shuhaibar, Leia C.; Warren, Gordon L.; Mansky, Kim C.; Jaffe, Laurinda A.; Potter, Lincoln R.; Romoli, Simone; Bauch, Tobias; Dröbner, Karoline; Eitner, Frank; Ruppert, Mihály; Radovits, Tamás; Korkmaz-Icöz, Sevil; Li, Shiliang; Hegedűs, Péter; Loganathan, Sivakanan; Németh, Balázs Tamás; Oláh, Attila; Mátyás, Csaba; Benke, Kálmán; Merkely, Béla; Karck, Matthias; Szabó, Gábor; Scheib, Ulrike; Broser, Matthias; Mukherjee, Shatanik; Stehfest, Katja; Gee, Christine E.; Körschen, Heinz G.; Oertner, Thomas G.; Hegemann, Peter; Schmidt, Hannes; Dickey, Deborah M.; Dumoulin, Alexandre; Kühn, Ralf; Jaffe, Laurinda; Potter, Lincoln R.; Rathjen, Fritz G.; Schobesberger, Sophie; Wright, Peter; Poulet, Claire; Mansfield, Catherine; Friebe, Andreas; Harding, Sian E.; Nikolaev, Viacheslav O.; Gorelik, Julia; Kollau, Alexander; Opelt, Marissa; Wölkart, Gerald; Gorren, Antonius C. F.; Russwurm, Michael; Koesling, Doris; Schrammel, Astrid; Mayer, Bernd; Schwaerzer, Gerburg K.; Casteel, Darren E.; Dalton, Nancy D.; Gu, Yusu; Zhuang, Shunhui; Milewicz, Dianna M.; Peterson, Kirk L.; Pilz, Renate; Schwiering, Fabian; Aue, Annemarie; Groneberg, Dieter; Friebe, Andreas; Argyriou, Aikaterini I.; Makrynitsa, Garyfalia; Alexandropoulos, Ioannis I.; Stamopoulou, Andriana; Bantzi, Marina; Giannis, Athanassios; Topouzis, Stavros; Papapetropoulos, Andreas; Spyroulias, Georgios A.; Stuehr, Dennis J.; Ghosh, Arnab; Dai, Yue; Misra, Saurav; Tchernychev, Boris; Jung, Joon; Liu, Guang; Silos-Santiago, Inmaculada; Hannig, Gerhard; Dao, Vu Thao-Vi; Deile, Martin; Nedvetsky, Pavel I.; Güldner, Andreas; Ibarra-Alvarado, César; Gödecke, Axel; Schmidt, Harald H. H. W.; Vachaviolos, Angelos; Gerling, Andrea; Thunemann, Martin; Lutz, Stefan Z.; Häring, Hans-Ulrich; Krüger, Marcel A.; Pichler, Bernd J.; Shipston, Michael J.; Feil, Susanne; Feil, Robert; Vandenwijngaert, Sara; Ledsky, Clara D.; Agha, Obiajulu; Hu, Dongjian; Domian, Ibrahim J.; Buys, Emmanuel S.; Newton-Cheh, Christopher; Bloch, Donald B.; Voussen, Barbara; Beck, Katharina; Mauro, Nadine; Keppler, Jonas; Friebe, Andreas; Ferreira, Wilson A., Jr; Chweih, Hanan; Brito, Pamela L.; Almeida, Camila B.; Penteado, Carla F. F.; Saad, Sara S. O.; Costa, Fernando F.; Frenette, Paul S.; Brockschnieder, Damian; Stasch, Johannes-Peter; Sandner, Peter; Conran, Nicola; Zimmer, Daniel P.; Tobin, Jenny; Shea, Courtney; Sarno, Renee; Long, Kimberly; Jacobson, Sarah; Tang, Kim; Germano, Peter; Wakefield, James; Banijamali, Ali; Im, G-Yoon Jamie; Sheppeck, James E., II; Profy, Albert T.; Todd Milne, G.; Currie, Mark G.; Masferrer, Jaime L.; on behalf of the Ironwood team; RD-CURE consortium
(sGC)-cyclic guanosine monophosphate (cGMP) ...
... of Pseudomonas isolates. ExoY has adenylyl  cyclase 
The Pseudomonas aeruginosa Exoenzyme Y: A Promiscuous Nucleotidyl Cyclase Edema Factor and Virulence Determinant
The Pseudomonas aeruginosa Exoenzyme Y: A Promiscuous Nucleotidyl Cyclase Edema Factor and Virulence Determinant
Morrow, K. Adam; Frank, Dara W.; Balczon, Ron; Stevens, Troy
activity that is dependent upon its ...
... transduction systems including adenylyl  cyclase 
G-Proteins in Vascular Complications of Diabetes
G-Proteins in Vascular Complications of Diabetes
Anand-Srivastava, Madhu B.
/cAMP and phospholipase C (PLC)/phosphatidyl ...
... ends, known as ionone rings, resulting from a  cyclase 
Carotenoid Production by Filamentous Fungi and Yeasts
Carotenoid Production by Filamentous Fungi and Yeasts
Avalos, Javier; Nordzieke, Steffen; Parra, Obdulia; Pardo-Medina, Javier; Carmen Limón, M.
enzymatic activity. ...
... data establish that CruA6803 is a lycopene  cyclase 
Synechocystis sp. PCC 6803 CruA (sll0147) encodes lycopene cyclase and requires bound chlorophyll a for activity
Synechocystis sp. PCC 6803 CruA (sll0147) encodes lycopene cyclase and requires bound chlorophyll a for activity
Xiong, Wei; Shen, Gaozhong; Bryant, Donald A.
and that it requires a bound Chl a molecule ...
... adenosine and guanosine (produced by adenylyl  cyclase 
3′,5′-cIMP as Potential Second Messenger in the Vascular Wall
3′,5′-cIMP as Potential Second Messenger in the Vascular Wall
Leung, Susan W. S.; Gao, Yuansheng; Vanhoutte, Paul M.
and guanylyl ...
... into the catalytic mechanism of lycopene  cyclase 
Generation of lycopene-overproducing strains of the fungus Mucor circinelloides reveals important aspects of lycopene formation and accumulation
Generation of lycopene-overproducing strains of the fungus Mucor circinelloides reveals important aspects of lycopene formation and accumulation
Zhang, Yingtong; Chen, Haiqin; Navarro, Eusebio; López-García, Sergio; Chen, Yong Q.; Zhang, Hao; Chen, Wei; Garre, Victoriano
and regulatory process during lycopene ...
... to their cognate G protein and to adenylyl  cyclase 
Allosterism Within GPCR Oligomers: Back to Symmetry
Allosterism Within GPCR Oligomers: Back to Symmetry
Ferré, Sergi
seems to constitute a common structure of a ...
... EAL domain of STM1703, solely, diguanylate  cyclase 
Detailed analysis of c-di-GMP mediated regulation of csgD expression in Salmonella typhimurium
Detailed analysis of c-di-GMP mediated regulation of csgD expression in Salmonella typhimurium
Ahmad, Irfan; Cimdins, Annika; Beske, Timo; Römling, Ute
and phosphodiesterase activities are required ...
... 16 Mg-protoporphyrin IX monomethyl ester  cyclase 
Biochemistry of Chlorophyll Biosynthesis in Photosynthetic Prokaryotes
Biochemistry of Chlorophyll Biosynthesis in Photosynthetic Prokaryotes
Fujita, Yuichi; Yamakawa, Hisanori
(oxygen independent) 4.–.–.– bchE chlE ...
... high structure-based homology between the  cyclase 
Mammalian Nucleotidyl Cyclases and Their Nucleotide Binding Sites
Mammalian Nucleotidyl Cyclases and Their Nucleotide Binding Sites
Dove, Stefan
species. ...
... two-hybrid (BACTH, for “Bacterial Adenylate  Cyclase 
Protein–Protein Interaction: Bacterial Two-Hybrid
Protein–Protein Interaction: Bacterial Two-Hybrid
Karimova, Gouzel; Gauliard, Emilie; Davi, Marilyne; Ouellette, Scot P.; Ladant, Daniel
-Based Two-Hybrid”) system is a simple and ...
... a bacterial two-hybrid system where adenylate  cyclase 
Evidence for the formation of ScbR/ScbR2 heterodimers and identification of one of the regulatory targets in Streptomyces coelicolor
Evidence for the formation of ScbR/ScbR2 heterodimers and identification of one of the regulatory targets in Streptomyces coelicolor
Li, Xiao; Wang, Juan; Shi, Mingxin; Wang, Weishan; Corre, Christophe; Yang, Keqian
activity was reconstituted in Escherichia ...
... is then metabolized by lycopene epsilon-  cyclase 
Genetic diversity of genes involved in the carotenoid pathway of Carica papaya L. and their expression during fruit ripening
Genetic diversity of genes involved in the carotenoid pathway of Carica papaya L. and their expression during fruit ripening
Saengmanee, Pimpilai; Burns, Parichart; Chaisan, Tanapon; Thaipong, Kriengsak; Siriphanich, Jingtair
(LYCE) and lycopene beta- ...
... activation of adenylyl cyclaseAdenylyl  cyclase 
GI Peptides, Energy Balance, and Cancer
GI Peptides, Energy Balance, and Cancer
Bruno, Debora S.; Wolfe, M. Michael
[95]. ...
... a single GGDEF domainGGDEF domain diguanylate  cyclase 
Enzymatic Production of c-di-GMP Using a Thermophilic Diguanylate Cyclase
Enzymatic Production of c-di-GMP Using a Thermophilic Diguanylate Cyclase
Venkataramani, Prabhadevi; Liang, Zhao-Xun
(DGC) GGDEF domain diguanylate ...
... cytochrome P450 monooxygenases and a putative  cyclase 
Comparative transcriptomics of mountain pine beetle pheromone-biosynthetic tissues and functional analysis of CYP6DE3
Comparative transcriptomics of mountain pine beetle pheromone-biosynthetic tissues and functional analysis of CYP6DE3
Nadeau, J. A.; Petereit, J.; Tillett, R. L.; Jung, K.; Fotoohi, M.; MacLean, M.; Young, S.; Schlauch, K.; Blomquist, G. J.; Tittiger, C.
for further studies. ...
... emphasis on the involvement of the guanylate  cyclase 
The triterpenoid alpha, beta-amyrin prevents the impaired aortic vascular reactivity in high-fat diet-induced obese mice
The triterpenoid alpha, beta-amyrin prevents the impaired aortic vascular reactivity in high-fat diet-induced obese mice
Santos, Flávia Almeida; Carvalho, Karine Maria Martins Bezerra; Batista-Lima, Francisco José; Nunes, Paulo Iury Gomes; Viana, Ana Flávia Seraine Custódio; Carvalho Almeida da Silva, Armenio André; Cruz Fonseca, Said Gonçalves; Chaves, Mariana Helena; Rao, Vietla Satyanarayana; Magalhães, Pedro Jorge Caldas; Brito, Teresinha Silva
-K+ channel pathway in the vascular ...
... (A2ARs) and the A2AR-triggered adenylate  cyclase 
Adenosine produced from adenine nucleotides through an interaction between apoptotic cells and engulfing macrophages contributes to the appearance of transglutaminase 2 in dying thymocytes
Adenosine produced from adenine nucleotides through an interaction between apoptotic cells and engulfing macrophages contributes to the appearance of transglutaminase 2 in dying thymocytes
Sándor, Katalin; Pallai, Anna; Duró, Edina; Legendre, Pascal; Couillin, Isabelle; Sághy, Tibor; Szondy, Zsuzsa
signaling pathway. ...
... (CaM.2) which in turn activates an adenylyl  cyclase 
Gravitaxis in Euglena
Gravitaxis in Euglena
Häder, Donat-P.; Hemmersbach, Ruth
producing cAMP from ATP. ...
... screeningscreening for diguanylate  cyclase 
Live Flow Cytometry Analysis of c-di-GMP Levels in Single Cell Populations
Live Flow Cytometry Analysis of c-di-GMP Levels in Single Cell Populations
Yeo, Jongchan; Wang, Xin C.; Hammond, Ming C.
activity, (2) analyzing c-di-GMP levels under ...
... which leads to inhibition of adenylate  cyclase 
Partial Adenosine A1 Agonist in Heart Failure
Partial Adenosine A1 Agonist in Heart Failure
Dinh, Wilfried; Albrecht-Küpper, Barbara; Gheorghiade, Mihai; Voors, Adriaan A.; Laan, Michael; Sabbah, Hani N.
activity, modulation of protein kinase C, and ...
... OLA is formed by olivetolic acid  cyclase 
Cannabinoids: Biosynthesis and Biotechnological Applications
Cannabinoids: Biosynthesis and Biotechnological Applications
Sirikantaramas, Supaart; Taura, Futoshi
(Gange et al. 2012), the first plant ...
... endogenous S1P receptors mediate adenylyl  cyclase 
Sphingosine-1-Phosphate (S1P) Signaling in Neural Progenitors
Sphingosine-1-Phosphate (S1P) Signaling in Neural Progenitors
Callihan, Phillip; Alqinyah, Mohammed; Hooks, Shelley B.
inhibition, phospholipase C activation, ...
... is a 400 kDa photoactivated adenylyl  cyclase 
Photomovement in Euglena
Photomovement in Euglena
Häder, Donat-P.; Iseki, Mineo
(PAC) which consists of two α- and two ...