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... new pair of degenerate primers targeting the  cyclase 
A method to type the potential angucycline producers in actinomycetes isolated from marine sponges
A method to type the potential angucycline producers in actinomycetes isolated from marine sponges
Ouyang, Yongchang; Wu, Houbo; Xie, Lianwu; Wang, Guanghua; Dai, Shikun; Chen, Minjie; Yang, Keqian; Li, Xiang
genes that are involved in the aromatization ...
... effectors, such as inhibition of adenylyl  cyclase 
Opioid Receptor Signal Transduction Mechanisms
Opioid Receptor Signal Transduction Mechanisms
Law, Ping-Yee
[21, 37] and calcium channels activities ...
... the GAF domain in the cyanobacterial adenylyl  cyclase 
The GAF-Tandem Domain of Phosphodiesterase 5 as a Potential Drug Target
The GAF-Tandem Domain of Phosphodiesterase 5 as a Potential Drug Target
Schultz, Joachim E.; Dunkern, Torsten; Gawlitta-Gorka, Elvira; Sorg, Gabriele
CyaB1. ...
... identified, namely, regulation of guanylyl  cyclase 
Adaptation of Mammalian Photoreceptors to Background Light: Putative Role for Direct Modulation of Phosphodiesterase
Adaptation of Mammalian Photoreceptors to Background Light: Putative Role for Direct Modulation of Phosphodiesterase
Fain, Gordon L
, modulation of activated rhodopsin lifetime, ...
... transduction systems including adenylyl  cyclase 
Modulation of Gi Protein Expression in Hypertension: Molecular Mechanisms
Modulation of Gi Protein Expression in Hypertension: Molecular Mechanisms
Anand-Srivastava, Madhu B.
–cAMP and phospholipase C ...
... GPCRs that function by inhibiting adenylate  cyclase 
Nitric oxide/cGMP pathway signaling actively down-regulates α4β1-integrin affinity: an unexpected mechanism for inducing cell de-adhesion
Nitric oxide/cGMP pathway signaling actively down-regulates α4β1-integrin affinity: an unexpected mechanism for inducing cell de-adhesion
Chigaev, Alexandre; Smagley, Yelena; Sklar, Larry A
and inducing calcium mobilization. ...
... Adenosine-induced vasorelaxation via adenylyl  cyclase 
Clopidogrel improves endothelial function and NO bioavailability by sensitizing adenylyl cyclase in rats with congestive heart failure
Clopidogrel improves endothelial function and NO bioavailability by sensitizing adenylyl cyclase in rats with congestive heart failure
Schäfer, Andreas; Fraccarollo, Daniela; Pförtsch, Stephanie; Loch, Elena; Neuser, Jonas; Vogt, Christian; Bauersachs, Johann
stimulation was attenuated in CHF and ...
... inhibition of adenylate cyclaseAdenylate  cyclase 
Neurochemistry of Endogenous Antinociception
Neurochemistry of Endogenous Antinociception
Horvath, Gyongyi
(AC) (Jones and Dunlop, 2007). ...
... blue (10 μM), a non-specific guanylate  cyclase 
Urodilatin increases renal dopamine uptake: intracellular network involved
Urodilatin increases renal dopamine uptake: intracellular network involved
Choi, Marcelo R.; Citarella, Marisa R.; Lee, Brenda M.; Lucano, Florencia; Fernández, Belisario E.
inhibitor, and by ...
... and enhances forskolin-stimulated adenylyl  cyclase 
9-Tetrahydrocannabinol-dependent mice undergoing withdrawal display impaired spatial memory
9-Tetrahydrocannabinol-dependent mice undergoing withdrawal display impaired spatial memory
Wise, Laura E.; Varvel, Stephen A.; Selley, Dana E.; Wiebelhaus, Jason M.; Long, Kelly A.; Middleton, Lisa S.; Sim-Selley, Laura J.; Lichtman, Aron H.
activity in cerebellum, an effect opposite ...
... (IbTX), blockers of soluble guanylyl  cyclase 
Mechanisms involved in the nitric oxide-induced vasorelaxation in porcine prostatic small arteries
Mechanisms involved in the nitric oxide-induced vasorelaxation in porcine prostatic small arteries
Fernandes, Vítor S.; Martínez-Sáenz, Ana; Recio, Paz; Ribeiro, Ana S. F.; Sánchez, Ana; Martínez, María Pilar; Martínez, Ana Cristina; García-Sacristán, Albino; Orensanz, Luis M.; Prieto, Dolores; Hernández, Medardo
and large conductance Ca2+-activated K+ ...
... lycopene is catalyzed by the enzyme lycopene  cyclase 
Molecular Evolution of Lycopene Cyclases Involved in the Formation of Carotenoids in Eukaryotic Algae
Molecular Evolution of Lycopene Cyclases Involved in the Formation of Carotenoids in Eukaryotic Algae
Cui, Hongli; Wang, Yinchu; Qin, Song
(LCY), which is structurally and functionally ...
... Lycopene beta-  cyclase 
cDNA cloning of a novel gene codifying for the enzyme lycopene β-cyclase from Ficus carica and its expression in Escherichia coli
cDNA cloning of a novel gene codifying for the enzyme lycopene β-cyclase from Ficus carica and its expression in Escherichia coli
Araya-Garay, José Miguel; Feijoo-Siota, Lucía; Veiga-Crespo, Patricia; Villa, Tomás González
(β-LCY) is the key enzyme that modifies the ...
... autoradiography and inhibition of adenylyl  cyclase 
Desensitization of δ-opioid receptors in nucleus accumbens during nicotine withdrawal
Desensitization of δ-opioid receptors in nucleus accumbens during nicotine withdrawal
McCarthy, Michael J.; Zhang, Hailing; Neff, Norton H.; Hadjiconstantinou, Maria
activity. ...
... the abundance of a calcium-sensitive adenylyl  cyclase 
Adenylyl cyclase 8 is central to glucagon-like peptide 1 signalling and effects of chronically elevated glucose in rat and human pancreatic beta cells
Adenylyl cyclase 8 is central to glucagon-like peptide 1 signalling and effects of chronically elevated glucose in rat and human pancreatic beta cells
Roger, B.; Papin, J.; Vacher, P.; Raoux, M.; Mulot, A.; Dubois, M.; Kerr-Conte, J.; Voy, B. H.; Pattou, F.; Charpentier, G.; Jonas, J.-C.; Moustaïd-Moussa, N.; Lang, J.
(ADCY8) and GLP-1 receptor (GLP1R). ...
... cell function(s), such as guanylyl  cyclase 
Signaling in the Endothelium
Signaling in the Endothelium
Marín-García, José
, mitochondrial iron–sulfur cluster enzymes, ...
... CD38 gene expression and CD38 ADP-ribosyl  cyclase 
HIV-1 and IL-1β regulate astrocytic CD38 through mitogen-activated protein kinases and nuclear factor-κB signaling mechanisms
HIV-1 and IL-1β regulate astrocytic CD38 through mitogen-activated protein kinases and nuclear factor-κB signaling mechanisms
Mamik, Manmeet K; Banerjee, Sugato; Walseth, Timothy F; Hirte, Renee; Tang, Lin; Borgmann, Kathleen; Ghorpade, Anuja
activity assays were performed to analyze ...
... filtration, scintillation counting Adenylyl  cyclase 
Characterizing the Pharmacology of G Protein-Coupled Receptors in Transfected Cell Lines
Characterizing the Pharmacology of G Protein-Coupled Receptors in Transfected Cell Lines
Seely, Kathryn A.; Prather, Paul L.
assay Seed cells – 80% confluence; ...
... to forskolin, an activator of the adenylate  cyclase 
Chronic sympathetic activation promotes downregulation of β-adrenoceptor-mediated effects in the guinea pig heart independently of structural remodeling and systolic dysfunction
Chronic sympathetic activation promotes downregulation of β-adrenoceptor-mediated effects in the guinea pig heart independently of structural remodeling and systolic dysfunction
Soltysinska, Ewa; Thiele, Stefanie; Olesen, Søren Peter; Osadchii, Oleg E.
catalytic subunit, were well preserved in ...
... increase in cAMP levels is due to adenylyl  cyclase 
A Fission Yeast-Based Platform for Phosphodiesterase Inhibitor HTSs and Analyses of Phosphodiesterase Activity
A Fission Yeast-Based Platform for Phosphodiesterase Inhibitor HTSs and Analyses of Phosphodiesterase Activity
Demirbas, Didem; Ceyhan, Ozge; Wyman, Arlene R.; Hoffman, Charles S.
activation, while feedback regulation to ...
... second messenger molecules: adenylate  cyclase 
Rapid Signaling Pathways
Rapid Signaling Pathways
Marín-García, José
(AC; produces cAMP) and phospholipase C [PLC; ...
... agents, inhibition of platelet adenylyl  cyclase 
Historical perspective on ADP-induced platelet activation
Historical perspective on ADP-induced platelet activation
Packham, Marian A.; Rand, Margaret L.
, increase in cytosolic free calcium, and ...
... the platelet, subsequently inhibits adenylyl  cyclase 
Time-resolved in silico modeling of fine-tuned cAMP signaling in platelets: feedback loops, titrated phosphorylations and pharmacological modulation
Time-resolved in silico modeling of fine-tuned cAMP signaling in platelets: feedback loops, titrated phosphorylations and pharmacological modulation
Wangorsch, Gaby; Butt, Elke; Mark, Regina; Hubertus, Katharina; Geiger, Jörg; Dandekar, Thomas; Dittrich, Marcus
(AC) but as well activates PDE3. ...
... toxin targets and activates the adenylate  cyclase 
Toxins of Vibrio cholerae and Their Role in Inflammation, Pathogenesis, and Immunomodulation
Toxins of Vibrio cholerae and Their Role in Inflammation, Pathogenesis, and Immunomodulation
Walia, Kamini; Ganguly, Nirmal Kumar
within host epithelial cells, provoking the ...
... main signaling pathways such as AC (adenylate  cyclase 
Biological and Pharmacological Aspects of Histamine Receptors and Their Ligands
Biological and Pharmacological Aspects of Histamine Receptors and Their Ligands
Shahid, Mohammed; Tripathi, Trivendra; Khan, Rahat Ali; Khardori, Nancy; Al-Sultan, Ali Ibrahim; AL-Mohammed, Hamdan Ibrahim; Alsultan, Abdulrahman A.; Huq, Anwar; Khan, Aijaz Ahmed; Siddiqui, Mashiatullah
), PKC (protein kinase C), PKA (protein ...