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... and neurotransmission. The guanylate  cyclase 
The crystal structure of the catalytic domain of a eukaryotic guanylate cyclase
The crystal structure of the catalytic domain of a eukaryotic guanylate cyclase
Winger, Jonathan A; Derbyshire, Emily R; Lamers, Meindert H; Marletta, Michael A; Kuriyan, John
catalytic module, for which no structure has ...
... We show here that this bacterium possesses a  cyclase 
Conversion of the lycopene monocyclase of Myxococcus xanthus into a bicyclase
Conversion of the lycopene monocyclase of Myxococcus xanthus into a bicyclase
Iniesta, Antonio A.; Cervantes, María; Murillo, Francisco J.
belonging to the group of the heterodimeric ...
... abstract available Synonyms Synonyms Adenylyl  cyclase 
Adenylyl Cyclases
Adenylyl Cyclases
Johnson, Roger A.
(preferred); Adenylate ...
... cyclases. Mapping the whole set of  cyclase 
Lineage-Specific Domain Fusion in the Evolution of Purine Nucleotide Cyclases in Cyanobacteria
Lineage-Specific Domain Fusion in the Evolution of Purine Nucleotide Cyclases in Cyanobacteria
Wu, Jinyu; Bai, Jie; Bao, Qiyu; Zhao, Fangqing
domain architectures from diverse prokaryotic ...
... domain, kinase-like domain, and guanylate  cyclase 
Identification of Guanylate Cyclases and Related Signaling Proteins in Sperm Tail from Sea Stars by Mass Spectrometry
Identification of Guanylate Cyclases and Related Signaling Proteins in Sperm Tail from Sea Stars by Mass Spectrometry
Nakachi, Mia; Matsumoto, Midori; Terry, Philip M.; Cerny, Ronald L.; Moriyama, Hideaki
domain. ...
... to adrenaline, is produced by adenylyl  cyclase 
Guanylyl cyclase sees the light
Guanylyl cyclase sees the light
Tesmer, John JG
, an enzyme first characterized in 1958. ...
... receptors to effectors, e.g. adenylyl  cyclase 
Internalization and desensitization of adenosine receptors
Internalization and desensitization of adenosine receptors
Klaasse, Elisabeth C.; IJzerman, Adriaan P.; Grip, Willem J.; Beukers, Margot W.
. ...
... The pituitary adenylate  cyclase 
Identification of Intracellular Signaling Cascades Mediating the PACAP-induced Increase in Guinea Pig Cardiac Neuron Excitability
Identification of Intracellular Signaling Cascades Mediating the PACAP-induced Increase in Guinea Pig Cardiac Neuron Excitability
Tompkins, John D.; Parsons, Rodney L.
-activating polypeptide (PACAP) increases ...
... (cGMP), via activation of soluble guanylate  cyclase 
Platelet Hyperaggregability: Impaired Responsiveness to Nitric Oxide (“Platelet NO Resistance”) as a Therapeutic Target
Platelet Hyperaggregability: Impaired Responsiveness to Nitric Oxide (“Platelet NO Resistance”) as a Therapeutic Target
Rajendran, Sharmalar; Chirkov, Yuliy Y.
, is the principal mechanism of negative ...
... nitric oxide synthase (NOS) and guanylyl  cyclase 
GTP avoidance in Tetrahymena thermophila requires tyrosine kinase activity, intracellular calcium, NOS, and guanylyl cyclase
GTP avoidance in Tetrahymena thermophila requires tyrosine kinase activity, intracellular calcium, NOS, and guanylyl cyclase
Bartholomew, Janine; Reichart, Johnathan; Mundy, Romie; Recktenwald, Jacquelyn; Keyser, Shannon; Riddle, Mark; Kuruvilla, Heather
in GTP signaling. ...
... β 2-adrenergic receptor activates adenylate  cyclase 
Cardiovascular Activity
Cardiovascular Activity
Vogel, Hans Gerhard
resulting in an increase in the cyclic AMP ...
... receptors, namely the inhibition of adenylyl  cyclase 
Analgesic, Anti-inflammatory, and Anti-pyretic Activity
Analgesic, Anti-inflammatory, and Anti-pyretic Activity
Vogel, Hans Gerhard
, the activation of potassium channels and ...
... was abolished by SQ 22536 (adenylate  cyclase 
Genistein potentiates protein kinase A activity in porcine coronary artery
Genistein potentiates protein kinase A activity in porcine coronary artery
Ng, William W. H.; Keung, Wendy; Xu, Yan Chun; Ng, Kwok F. J.; Leung, George P. H.; Vanhoutte, Paul M.; Choy, Patrick C.; Man, Ricky Y. K.
blocker), but not by NF 449 (Gs protein ...
... reaction and CD38 function by ADP-ribosyl  cyclase 
CD38/Cyclic ADP-Ribose Regulates Astrocyte Calcium Signaling: Implications for Neuroinflammation and HIV-1-Associated Dementia
CD38/Cyclic ADP-Ribose Regulates Astrocyte Calcium Signaling: Implications for Neuroinflammation and HIV-1-Associated Dementia
Banerjee, Sugato; Walseth, Timothy F.; Borgmann, Kathleen; Wu, Li; Bidasee, Keshore R.; Kannan, Mathur S.; Ghorpade, Anuja
activity. ...
... binding studies (A1, A2A, and A3) or adenylyl  cyclase 
Purines 2008 Meeting 29 June – 2 July 2008, Copenhagen, Denmark
Purines 2008 Meeting 29 June – 2 July 2008, Copenhagen, Denmark
activity assay (A2B). ...
... showed that members of the polyketide  cyclase 
The Bet v 1 fold: an ancient, versatile scaffold for binding of large, hydrophobic ligands
The Bet v 1 fold: an ancient, versatile scaffold for binding of large, hydrophobic ligands
Radauer, Christian; Lackner, Peter; Breiteneder, Heimo
family and the activator of Hsp90 ATPase ...
... encodes a putative 267-amino acid guanylyl  cyclase 
A guanylyl cyclase-like gene is associated with Gibberella ear rot resistance in maize (Zea mays L.)
A guanylyl cyclase-like gene is associated with Gibberella ear rot resistance in maize (Zea mays L.)
Yuan, J.; Ali, M. Liakat; Taylor, J.; Liu, J.; Sun, G.; Liu, W.; Masilimany, P.; Gulati-Sakhuja, A.; Pauls, K. P.
-like protein (ZmGC1) was characterized and ...
... to Cα2+ and K+ channels as well as adenyl  cyclase 
Psychotropic and Neurotropic Activity
Psychotropic and Neurotropic Activity
Vogel, Hans Gerhard
in neurons and hence is classified as a ...
... 2,3-Oxidosqualene cyclase2,3-oxidosqualene  cyclase 
Anti-Atherosclerotic Activity
Anti-Atherosclerotic Activity
Vogel, Hans Gerhard
forming lanosterol lanosterol from ...
... with a role for cAMP during mating, adenylyl  cyclase 
Gametic Cell Adhesion and Fusion in the Unicellular Alga Chlamydomonas
Gametic Cell Adhesion and Fusion in the Unicellular Alga Chlamydomonas
Wilson, Nedra F.
activity was detected in both cell bodies and ...
... tested epidermal beta‐adrenergic adenylate  cyclase 
Endocrinology
Endocrinology
Vogel, Hans Gerhard
responses in pigs after topical application ...
... of Mg-protoporphyrin IX monomethyl ester  cyclase 
Recent overview of the Mg branch of the tetrapyrrole biosynthesis leading to chlorophylls
Recent overview of the Mg branch of the tetrapyrrole biosynthesis leading to chlorophylls
Masuda, Tatsuru
), and CAO (encoding chlorophyllide a ...
... expressing complementary domains of adenylate  cyclase 
Evidence for direct interactions between the mercuric ion transporter (MerT) and mercuric reductase (MerA) from the Tn501mer operon
Evidence for direct interactions between the mercuric ion transporter (MerT) and mercuric reductase (MerA) from the Tn501mer operon
Schue, Mathieu; Glendinning, Kerry J.; Hobman, Jon L.; Brown, Nigel L.
. ...
... of the β-adrenergic-receptor-linked adenylyl  cyclase 
Receptor-independent sensitization of the adenylyl cylase after chronic treatment with cyclosporine A
Receptor-independent sensitization of the adenylyl cylase after chronic treatment with cyclosporine A
Simonis, G.; Christ, T.; Bährle, S. K.; Pena, M.; Schoen, S. P.; Marquetant, R.; Ravens, U.; Strasser, R. H.
(AC) system contributes to hypertension is ...
... (non-receptor activation of the adenylate  cyclase 
Activity on the Gastrointestinal Tract
Activity on the Gastrointestinal Tract
Vogel, Hans Gerhard
). ...