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... extent than in wild type cells. Adenylyl  cyclase 
A novel Dictyostelium RasGEF required for chemotaxis and development
A novel Dictyostelium RasGEF required for chemotaxis and development
Arigoni, Maddalena; Bracco, Enrico; Lusche, Daniel F; Kae, Helmut; Weeks, Gerald; Bozzaro, Salvatore
activation in response to cAMP pulses is ...
... downstream effec tors, namely, adenylyl  cyclase 
Methods for the Detection of Altered β-Adrenergic Receptor Signaling Pathways in Hypertrophied Hearts
Methods for the Detection of Altered β-Adrenergic Receptor Signaling Pathways in Hypertrophied Hearts
J. Wolf, Matthew; Tachibana, Hideo; A. Rockman, Howard
. ...
... β-adrenergic receptors and brain adenylate  cyclase 
β-adrenergic receptor density and adenylate cyclase activity in lead-exposed rat brain after cessation of lead exposure
β-adrenergic receptor density and adenylate cyclase activity in lead-exposed rat brain after cessation of lead exposure
Chang, Huoy-Rou; Tsao, Der-An; Yu, Hsin-Su; Ho, Chi-Kung
activity after lead exposure was withdrawn. ...
... with the exception of the lycopene  cyclase 
Carotenoid biosynthesis in Gloeobacter violaceus PCC4721 involves a single crtI-type phytoene desaturase instead of typical cyanobacterial enzymes
Carotenoid biosynthesis in Gloeobacter violaceus PCC4721 involves a single crtI-type phytoene desaturase instead of typical cyanobacterial enzymes
Steiger, Sabine; Jackisch, Yvonne; Sandmann, Gerhard
gene. ...
... used a homology modeling approach of the GTP  cyclase 
Linking enzyme sequence to function using conserved property difference locator to identify and annotate positions likely to control specific functionality
Linking enzyme sequence to function using conserved property difference locator to identify and annotate positions likely to control specific functionality
Mayer, Kimberly M; McCorkle, Sean R; Shanklin, John
on the crystallographically-determined ATP ...
... cyclic AMP due to an activation of adenylyl  cyclase 
Insect octopamine receptors: a new classification scheme based on studies of cloned Drosophila G-protein coupled receptors
Insect octopamine receptors: a new classification scheme based on studies of cloned Drosophila G-protein coupled receptors
Evans, Peter D.; Maqueira, Braudel
activity (Evans 1984b, c, 1987). ...
... cascades such as Gαolf[Gγ7], adenylyl  cyclase 
Phenotypic studies on dopamine receptor subtype and associated signal transduction mutants: insights and challenges from 10 years at the psychopharmacology–molecular biology interface
Phenotypic studies on dopamine receptor subtype and associated signal transduction mutants: insights and challenges from 10 years at the psychopharmacology–molecular biology interface
Waddington, John L.; O'Tuathaigh, Colm; O'Sullivan, Gerard; Tomiyama, Katsunori; Koshikawa, Noriaki; Croke, David T.
type 5, PKA [RIIβ] and DARPP-32. ...
... human A2B receptor was determined in adenylyl  cyclase 
2- and 8-alkynyl-9-ethyladenines: Synthesis and biological activity at human and rat adenosine receptors
2- and 8-alkynyl-9-ethyladenines: Synthesis and biological activity at human and rat adenosine receptors
Volpini, Rosaria; Costanzi, Stefano; Lambertucci, Catia; Vittori, Sauro; Martini, Claudia; Trincavelli, M. Letizia; Klotz, Karl-Norbert; Cristalli, Gloria
experiments. ...
... signal via the hormone-sensitive adenylyl  cyclase 
Effects of the C-terminal Peptide of the αs subunit of the G protein on the regulation of Adenylyl Cyclase and Protein Kinase A activities by Biogenic Amines and Glucagon in Mollusk and Rat Muscles
Effects of the C-terminal Peptide of the αs subunit of the G protein on the regulation of Adenylyl Cyclase and Protein Kinase A activities by Biogenic Amines and Glucagon in Mollusk and Rat Muscles
Shpakov, A. O.; Korol’kov, V. I.; Plesneva, S. A.; Kuznetsova, L. A.; Pertseva, M. N.
signal system, whose major components are ...
... phospholipase C (PLC) and adenylate  cyclase 
Alpha1-and beta2-adrenoceptors in the human liver with mass-forming intrahepatic cholangiocarcinoma: density and coupling to adenylate cyclase and phospholipase C
Alpha1-and beta2-adrenoceptors in the human liver with mass-forming intrahepatic cholangiocarcinoma: density and coupling to adenylate cyclase and phospholipase C
Kassahun, W. T.; Günl, B.; Tannapfel, A.; Ungemach, F. R.; Hauss, J.; Abraham, G.
(AC) was also studied. ...
... molecule NO. Activation of guanylyl  cyclase 
Gene inactivation of the β1 subunit of NO-sensitive guanylyl cyclase in mice
Gene inactivation of the β1 subunit of NO-sensitive guanylyl cyclase in mice
Friebe, Andreas; Mergia, Evanthia; Dangel, Oliver; Lange, Alexander; Koesling, Doris
by NO leads to the formation of the ...
... or LY83583 (an inhibitor of soluble guanylate  cyclase 
Endothelin-1 in osteoarthritic chondrocytes triggers nitric oxide production and upregulates collagenase production
Endothelin-1 in osteoarthritic chondrocytes triggers nitric oxide production and upregulates collagenase production
Manacu, Christina Alexandra; Martel-Pelletier, Johanne; Roy-Beaudry, Marjolaine; Pelletier, Jean-Pierre; Fernandes, Julio C; Shipkolye, Fazool S; Mitrovic, Dragoslav R; Moldovan, Florina
and of cGMP). ...
... nucleotides was determined. The adenylyl  cyclase 
In vitro functional responses of isolated human vaginal tissue to selective phosphodiesterase inhibitors
In vitro functional responses of isolated human vaginal tissue to selective phosphodiesterase inhibitors
Ückert, Stefan; Ehlers, Vicky; Nüser, Vivian; Oelke, Matthias; Kauffels, Wolfgang; Scheller, Friedemann; Jonas, Udo
stimulating agents forskolin and nitric oxide ...
... are given in bold italics: LCY-B, lycopene-β-  cyclase 
Regulation and Manipulation of the Biosynthesis of Abscisic Acid, Including the Supply of Xanthophyll Precursors
Regulation and Manipulation of the Biosynthesis of Abscisic Acid, Including the Supply of Xanthophyll Precursors
Taylor, Ian B.; Sonneveld, Tineke; Bugg, Timothy D. H.; Thompson, Andrew J.
; BCH, β-carotene hydroxylase; ZEP, ...
... signal via the hormone-sensitive adenylyl  cyclase 
Effects of the C-terminal peptide of the αs subunit of the G protein on the regulation of adenylyl cyclase and protein kinase A activities by biogenic amines and glucagon in mollusk and rat muscles
Effects of the C-terminal peptide of the αs subunit of the G protein on the regulation of adenylyl cyclase and protein kinase A activities by biogenic amines and glucagon in mollusk and rat muscles
Shpakov, A. O.; Korol’kov, V. I.; Plesneva, S. A.; Kuznetsova, L. A.; Pertseva, M. N.
signal system, whose major components are ...
... of histamine H1 receptors activates adenylyl  cyclase 
Involvement of the βγ subunits of G proteins in the cAMP response induced by stimulation of the histamine H1 receptor
Involvement of the βγ subunits of G proteins in the cAMP response induced by stimulation of the histamine H1 receptor
Maruko, Takeshi; Nakahara, Tsutomu; Sakamoto, Kenji; Saito, Maki; Sugimoto, Naotoshi; Takuwa, Yoh; Ishii, Kunio
through the release of Gβγ subunits from ...
... which are negatively coupled to adenylate  cyclase 
Cerebellar astrocytes co-express several ADP receptors. Presence of functional P2Y13-like receptors
Cerebellar astrocytes co-express several ADP receptors. Presence of functional P2Y13-like receptors
Carrasquero, Luz María G.; Delicado, Esmerilda G.; Jiménez, Ana I.; Pérez-Sen, Raquel; Miras-Portugal, M. Teresa
, in cerebellar astrocytes. ...
... 24 h whereas addition of soluble guanylate  cyclase 
Guanosine stimulates neurite outgrowth in PC12 cells via activation of heme oxygenase and cyclic GMP
Guanosine stimulates neurite outgrowth in PC12 cells via activation of heme oxygenase and cyclic GMP
Bau, Christian; Middlemiss, Pamela J.; Hindley, Shaun; Jiang, Shucui; Ciccarelli, Renata; Caciagli, Francesco; DiIorio, Patrizia; Werstiuk, Eva S.; Rathbone, Michel P.
(sGC) inhibitors abolished guanosine-induced ...
... (JAK/STAT), and adenylate/guanylate  cyclase 
VeloceGenomics: An Accelerated in Vivo Drug Discovery Approach to Rapidly Predict the Biologic, Drug-Like Activity of Compounds, Proteins, or Genes
VeloceGenomics: An Accelerated in Vivo Drug Discovery Approach to Rapidly Predict the Biologic, Drug-Like Activity of Compounds, Proteins, or Genes
Papoian, Ruben; Scherer, Andreas; Saulnier, Muriel; Staedtler, Frank; Cordier, André; Legay, Francois; Maurer, Gerard; Staeheli, Joerg; Vonderscher, Jacky; Chibout, Salah-Dine
pathways (Tables I and II). ...
... this is not due to inhibition of guanylate  cyclase 
Prior vasorelaxation enhances diadenosine polyphosphate-induced contractility of rat mesenteric resistance arteries
Prior vasorelaxation enhances diadenosine polyphosphate-induced contractility of rat mesenteric resistance arteries
Steinmetz, Martin; Le, Truc; Bierer, Stefan; Mey, Jozef Gabriel Rita; Schlatter, Eberhard
, which has been previously described to be ...
... sustained opioid signaling cause adenylyl  cyclase 
Look before leaping: combined opioids may not be the rave
Look before leaping: combined opioids may not be the rave
Davis, Mellar P.; LeGrand, Susan B.; Lagman, Ruth
superactivation and counteropioid responses ...
... They activate enterocytes via guanylate  cyclase 
Mechanisms of actions of guanylin peptides in the kidney
Mechanisms of actions of guanylin peptides in the kidney
Sindić, Aleksandra; Schlatter, Eberhard
C (GC-C) and increase the cellular ...
... the β1 sub-unit of soluble guanylate  cyclase 
Expression of neuronal nitric oxide synthase (nNOS) and nitric-oxide-induced changes in cGMP in the urothelial layer of the guinea pig bladder
Expression of neuronal nitric oxide synthase (nNOS) and nitric-oxide-induced changes in cGMP in the urothelial layer of the guinea pig bladder
Gillespie, J. I.; Markerink-van Ittersum, M.; Vente, J.
, protein kinase I or protein kinase II. ...
... Prucalopride stimulated adenylyl  cyclase 
Prucalopride is a partial agonist through human and porcine atrial 5-HT4 receptors: comparison with recombinant human 5-HT4 splice variants
Prucalopride is a partial agonist through human and porcine atrial 5-HT4 receptors: comparison with recombinant human 5-HT4 splice variants
Krobert, Kurt A.; Brattelid, Trond; Levy, Finn Olav; Kaumann, Alberto J.
as a partial agonist on 5-HT4(a), 5-HT4(b), ...
... oxide synthase (eNOS)/soluble guanylate  cyclase 
Endothelial nitric oxide synthase/soluble guanylate cyclase system in human nasal polyps
Endothelial nitric oxide synthase/soluble guanylate cyclase system in human nasal polyps
Escobar, Paloma; Márquez, Francisco J; Carrasco, Carolina; Alonso-Orgaz, Sergio; Fortes, José; Cenjor, Carlos; López-Farré, Antonio
(sGC) system in nasal polyps and control ...