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... been cloned and characterized: the adenylate  cyclase 
cAMP signaling in Aspergillus fumigatus is involved in the regulation of the virulence gene pksP and in defense against killing by macrophages
cAMP signaling in Aspergillus fumigatus is involved in the regulation of the virulence gene pksP and in defense against killing by macrophages
Liebmann, B.; Gattung, S.; Jahn, B.; Brakhage, A. A.
gene acyA, and gpaA and gpaB, both of which ...
... enzymes are required, ε- and β-lycopene  cyclase 
A novel type of lycopene ε-cyclase in the marine cyanobacterium Prochlorococcus marinus MED4
A novel type of lycopene ε-cyclase in the marine cyanobacterium Prochlorococcus marinus MED4
Stickforth, Per; Steiger, Sabine; Hess, Wolfgang R.; Sandmann, Gerhard
. ...
... We have isolated the pseudopterosin diterpene  cyclase 
Pseudopterosin biosynthesis—pathway elucidation, enzymology, and a proposed production method for anti-inflammatory metabolites from Pseudopterogorgia elisabethae
Pseudopterosin biosynthesis—pathway elucidation, enzymology, and a proposed production method for anti-inflammatory metabolites from Pseudopterogorgia elisabethae
Kohl, Amber C.; Ata, Athar; Kerr, Russell G.
product, elisabethatriene, using a ...
... this step is performed by a lycopene  cyclase 
Genetic basis of microbial carotenogenesis
Genetic basis of microbial carotenogenesis
Sieiro, C.; Poza, M.; Miguel, T.; Villa, T. G.
encoded by the crtL genes. ...
... Modulation of adenylyl  cyclase 
Assessing Opioid Regulation of Adenylyl Cyclase Activity in Intact Cells
Assessing Opioid Regulation of Adenylyl Cyclase Activity in Intact Cells
Thakker, Deepak R.; Ozsoy, Hatice Z.; Standifer, Kelly M.
activity constitutes one of the important ...
... protein, nitric oxide synthase, and adenylyl  cyclase 
Biochemical evidence for a P2Y-like receptor in Tetrahymena thermophila
Biochemical evidence for a P2Y-like receptor in Tetrahymena thermophila
Rosner, B. N.; Bartholomew, J. N.; Gaines, C. D.; Riddle, M. L.; Everett, H. A.; Rulapaugh, K. G.; Nickerson, L. E.; Marshall, M. R.; Kuruvilla, H. G.
, all of which are characteristic of some P2Y ...
... Inhibition of the soluble guanylyl  cyclase 
Mechanism of the positive contractile effect of nitric oxide on rat ventricular cardiomyocytes with positive force/frequency relationship
Mechanism of the positive contractile effect of nitric oxide on rat ventricular cardiomyocytes with positive force/frequency relationship
Langer, Markus; Lüttecke, Dirk; Schlüter, Klaus-Dieter
(sGC) by ...
... inhibition of nitric oxide synthase, guanylyl  cyclase 
Androgen receptor independent cardiovascular action of the antiandrogen flutamide
Androgen receptor independent cardiovascular action of the antiandrogen flutamide
Iliescu, Radu; Campos, Luciana A.; Schlegel, Wolfgang-Peter; Morano, Ingo; Baltatu, Ovidiu; Bader, Michael
, and tyrosine kinase but not by calmodulin ...
... in S. pombe, and cells lacking adenylate  cyclase 
The phospholipase B homolog Plb1 is a mediator of osmotic stress response and of nutrient-dependent repression of sexual differentiation in the fission yeast Schizosaccharomyces pombe
The phospholipase B homolog Plb1 is a mediator of osmotic stress response and of nutrient-dependent repression of sexual differentiation in the fission yeast Schizosaccharomyces pombe
Yang, P.; Du, H.; Hoffman, C. S.; Marcus, S.
activity mate promiscuously on rich media ...
... inhibition of forskolin-stimulated adenylate  cyclase 
β23-di- and α/β3-tetrapeptide derivatives as potent agonists at somatostatin sst4 receptors
β23-di- and α/β3-tetrapeptide derivatives as potent agonists at somatostatin sst4 receptors
Nunn, Caroline; Rueping, Magnus; Langenegger, Daniel; Schuepbach, Edi; Kimmerlin, Thierry; Micuch, Peter; Hurth, Konstanze; Seebach, Dieter; Hoyer, Daniel
activity, and stimulation of luciferase ...
... were also evaluated: we measured adenylyl  cyclase 
The effects of hydrocortisone on rat heart muscarinic and adrenergic α1, β1 and β2 receptors, propranolol-resistant binding sites and on some subsequent steps in intracellular signalling
The effects of hydrocortisone on rat heart muscarinic and adrenergic α1, β1 and β2 receptors, propranolol-resistant binding sites and on some subsequent steps in intracellular signalling
Mysliveček, Jaromír; Říčný, Jan; Kolář, František; Tuček†, Stanislav
activity (basal, isoprenaline- and ...
... that direct activators of adenylyl  cyclase 
Evidence for a significant role of a Gs-triggered mechanism unrelated to the activation of adenylyl cyclase in the cyclic AMP-independent relaxant response of guinea-pig tracheal smooth muscle
Evidence for a significant role of a Gs-triggered mechanism unrelated to the activation of adenylyl cyclase in the cyclic AMP-independent relaxant response of guinea-pig tracheal smooth muscle
Tanaka, Yoshio; Yamashita, Yoko; Yamaki, Fumiko; Horinouchi, Takahiro; Shigenobu, Koki; Koike, Katsuo
, such as forskolin and membrane-permeable ...
... through a mechanism involving adenylate-  cyclase 
Angiotensin-(1–7) stimulates water transport in rat inner medullary collecting duct: evidence for involvement of vasopressin V2 receptors
Angiotensin-(1–7) stimulates water transport in rat inner medullary collecting duct: evidence for involvement of vasopressin V2 receptors
Magaldi, Antonio J.; Cesar, Katia R.; Araújo, Magali; Simões e Silva, Ana C.; Santos, Robson A. S.
activation. ...
... domain occurs between the HNOB and the  cyclase 
Ancient conserved domains shared by animal soluble guanylyl cyclases and bacterial signaling proteins
Ancient conserved domains shared by animal soluble guanylyl cyclases and bacterial signaling proteins
Iyer, Lakshminarayan M; Anantharaman, Vivek; Aravind, L
domains in the animal SGCs. ...
... with respect to inhibition of adenyly  cyclase 
Activity of opioid ligands in cells expressing cloned mu opioid receptors
Activity of opioid ligands in cells expressing cloned mu opioid receptors
Gharagozlou, Parham; Demirci, Hasan; David Clark, J; Lameh, Jelveh
. ...
... at the expense of V by overexpression of ε-  cyclase 
Occurrence of the lutein-epoxide cycle in mistletoes of the Loranthaceae and Viscaceae
Occurrence of the lutein-epoxide cycle in mistletoes of the Loranthaceae and Viscaceae
Matsubara, Shizue; Morosinotto, Tomas; Bassi, Roberto; Christian, Anna-Luise; Fischer-Schliebs, Elke; Lüttge, Ulrich; Orthen, Birgit; Franco, Augusto C.; Scarano, Fabio R.; Förster, Britta; Pogson, Barry J.; Osmond, C. Barry
, a key enzyme for lutein synthesis. ...
... were abolished in the presence of guanylyl-  cyclase 
Role of constitutively expressed heme oxygenase-2 in the regulation of guinea pig coronary artery tone
Role of constitutively expressed heme oxygenase-2 in the regulation of guinea pig coronary artery tone
Gagov, Hristo; Kadinov, Boris; Hristov, Kiril; Boev, Kiril; Itzev, Dimiter; Bolton, Thomas; Duridanova, Dessislava
or protein kinase G antagonists. ...
... (ANPC) mediated-inhibition of adenylyl  cyclase 
Modulation of Atrial Natriuretic Peptide (ANP)-C Receptor and Associated Signaling by Vasoactive Peptides
Modulation of Atrial Natriuretic Peptide (ANP)-C Receptor and Associated Signaling by Vasoactive Peptides
Anand-Srivastava, Madhu B.; Boumati, Malika
without altering [125I]-ANP binding. ...
... of effector molecules, including adenylate  cyclase 
The G protein β subunit FGB1 regulates development and pathogenicity in Fusarium oxysporum
The G protein β subunit FGB1 regulates development and pathogenicity in Fusarium oxysporum
Jain, Sona; Akiyama, Kouichi; Kan, Takuya; Ohguchi, Tomizo; Takata, Renkichi
, ion channels and phospholipases (Clapham ...
... subject to debate. Protein kinase C, adenylyl  cyclase 
Ischemic preconditioning promotes a transient, but not sustained translocation of protein kinase C and sensitization of adenylyl cyclase
Ischemic preconditioning promotes a transient, but not sustained translocation of protein kinase C and sensitization of adenylyl cyclase
Simonis, Gregor; Weinbrenner, Christof; Strasser, Ruth H.
and β-adrenergic receptors are candidates for ...
... These hormones are known to activate adenylyl  cyclase 
Type VIII adenylyl cyclase in rat beta cells: coincidence signal detector/generator for glucose and GLP-1
Type VIII adenylyl cyclase in rat beta cells: coincidence signal detector/generator for glucose and GLP-1
Delmeire, D.; Flamez, D.; Hinke, S. A.; Cali, J. J.; Pipeleers, D.; Schuit, F.
in beta cells. ...
... stimulated by β-adrenoceptors and adenylyl  cyclase 
Nitric oxide generation mediated by β-adrenoceptors is impaired in platelets from patients with Type 2 diabetes mellitus
Nitric oxide generation mediated by β-adrenoceptors is impaired in platelets from patients with Type 2 diabetes mellitus
Queen, L. R.; Ji, Y.; Goubareva, I.; Ferro, A.
in Type 2 diabetic patients and control ...
... exhibited the property of inhibiting adenylyl  cyclase 
The Cox-2-Specific Inhibitor Celecoxib Inhibits Adenylyl Cyclase
The Cox-2-Specific Inhibitor Celecoxib Inhibits Adenylyl Cyclase
Saini, Shamsher S.; Gessell-Lee, Deborah L.; Peterson, Johnny W.
, an important enzyme forming the ...
... cAMP. cGMP is generated by soluble guanylyl  cyclase 
cAMP-independent relaxation of smooth muscle cells via Gs-coupled receptors
cAMP-independent relaxation of smooth muscle cells via Gs-coupled receptors
Peters, Stephan L. M.; Michel, Martin C.
in response to NO (generated by the ...
... and inhibition of NECA-stimulated adenylyl  cyclase 
9-Ethyladenine derivatives as adenosine receptor antagonists: 2- and 8-substitution results in distinct selectivities
9-Ethyladenine derivatives as adenosine receptor antagonists: 2- and 8-substitution results in distinct selectivities
Klotz, Karl-Norbert; Kachler, Sonja; Lambertucci, Catia; Vittori, Sauro; Volpini, Rosaria; Cristalli, Gloria
activity (A2B) in membranes prepared from CHO ...