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... synthesized a phospholipid–gemcitabine  conjugate 
A novel phospholipid gemcitabine conjugate is able to bypass three drug-resistance mechanisms
A novel phospholipid gemcitabine conjugate is able to bypass three drug-resistance mechanisms
Alexander, Richard L.; Greene, Bryan T.; Torti, Suzy V.; Kucera, Gregory L.
and a phospholipid–cytosine arabinoside ...
... to evaluate feasibility of sunitinib–CLIO  conjugate 
Sunitinib–CLIO Conjugate: A VEGFR/PDGFR-Targeting Active MR Probe
Sunitinib–CLIO Conjugate: A VEGFR/PDGFR-Targeting Active MR Probe
Noh, Gwang Tae; Kim, Mi-hyun; Suh, Ji-Yeon; Song, Youngkyu; Lee, Chang Kyung; Baek, Jin Hee; Lee, Yong Seok; Cho, Gyunggoo; Kim, EunJu; Kim, Young Ro; Cho, Hyung Joon; Lim, Dongyeol; Kim, Jeong Kon
as a vascular endothelial growth factor ...
... position (near or far), the dark  conjugate 
The horizontal dark oculomotor rest position
The horizontal dark oculomotor rest position
Kim, Eun H.; Alvarez, Tara L.
position (left to right), and the near ...
... experiments no adverse effect of either  conjugate 
Using the neurotransmitter serotonin to target imaging agents to glioblastoma cells
Using the neurotransmitter serotonin to target imaging agents to glioblastoma cells
Sturzu, Alexander; Sheikh, Sumbla; Klose, Uwe; Echner, Hartmut; Kalbacher, Hubert; Deeg, Martin; Nägele, Thomas; Horger, Marius; Ernemann, Ulrike; Heckl, Stefan
on the cells was observed. ...
... previous experiments we successfully used a  conjugate 
Novel bourgeonal fragrance conjugates for the detection of prostate cancer
Novel bourgeonal fragrance conjugates for the detection of prostate cancer
Sturzu, Alexander; Sheikh, Sumbla; Echner, Hartmut; Nägele, Thomas; Deeg, Martin; Schwentner, Christian; Horger, Marius; Ernemann, Ulrike; Heckl, Stefan
targeting the OR1D2 receptor via the ...
... Two alendronate-EP4 agonist (ALN-EP4a)  conjugate 
In vivo effects of two novel ALN-EP4a conjugate drugs on bone in the ovariectomized rat model for reversing postmenopausal bone loss
In vivo effects of two novel ALN-EP4a conjugate drugs on bone in the ovariectomized rat model for reversing postmenopausal bone loss
Hu, S.; Liu, C. C.; Chen, G.; Willett, T.; Young, R. N.; Grynpas, M. D.
drugs, C1 and C2, which differ in structure ...
... have been taken to introduce meningococcal  conjugate 
An evaluation of emerging vaccines for childhood meningococcal disease
An evaluation of emerging vaccines for childhood meningococcal disease
Choudhuri, Debajeet; Huda, Tanvir; Theodoratou, Evropi; Nair, Harish; Zgaga, Lina; Falconer, Rachel; Luksic, Ivana; Johnson, Hope L; Zhang, Jian Shayne F; El Arifeen, Shams; Nelson, Christopher B; Borrow, Ray; Campbell, Harry; Rudan, Igor
vaccine in these African countries. ...
... in an antigen-specific effector–target cell  conjugate 
Increased effector–target cell conjugate formation due to HLA restricted specific antigen recognition
Increased effector–target cell conjugate formation due to HLA restricted specific antigen recognition
Voss, Ching Y.; Deola, Sara; Fleisher, Thomas A.; Marincola, Francesco M.
formation. ...
... astatinated chimeric MAb (cMAb) U36 as a  conjugate 
In vitro evaluation of the astatinated chimeric monoclonal antibody U36, a potential candidate for treatment of head and neck squamous cell carcinoma
In vitro evaluation of the astatinated chimeric monoclonal antibody U36, a potential candidate for treatment of head and neck squamous cell carcinoma
Nestor, M.; Persson, M.; Dongen, G. A. M. S.; Jensen, H. J.; Lundqvist, H.; Anniko, M.; Tolmachev, V.
to selectively target and eradicate head ...
... human B-cell lymphomas (BCLs) in vitro. The  conjugate 
Antibody-targeted chemotherapy of B-cell lymphoma using calicheamicin conjugated to murine or humanized antibody against CD22
Antibody-targeted chemotherapy of B-cell lymphoma using calicheamicin conjugated to murine or humanized antibody against CD22
DiJoseph, John F.; Popplewell, Andrew; Tickle, Simon; Ladyman, Heather; Lawson, Alastair; Kunz, Arthur; Khandke, Kiran; Armellino, Douglas C.; Boghaert, Erwin R.; Hamann, Philip R.; Zinkewich-Peotti, Karen; Stephens, Sue; Weir, Neil; Damle, Nitin K.
of m5/44 with an acid-labile linker was ...
... carriage. In 1999, the first meningococcal  conjugate 
Meningococcal Vaccinations
Meningococcal Vaccinations
Crum-Cianflone, Nancy; Sullivan, Eva
vaccines were introduced and have been ...
... system (Fig. 1A) uses an antibody—enzyme  conjugate 
Nonradioactive Labeling and lmmunodetection of Recombinant Proteins
Nonradioactive Labeling and lmmunodetection of Recombinant Proteins
Oberfelder, Robert
, whereas both the secondary antibody-based ...
... certain medical conditions. Pneumococcal  conjugate 
Changing Epidemiology of Pneumococcal Disease in the Era of Conjugate Vaccines
Changing Epidemiology of Pneumococcal Disease in the Era of Conjugate Vaccines
Whitney, Cynthia G.
vaccines are changing both the epidemiology ...
... Results We found that the anti-bovine  conjugate 
The modification and evaluation of an ELISA test for the surveillance of Mycobacterium avium subsp. paratuberculosisinfection in wild ruminants
The modification and evaluation of an ELISA test for the surveillance of Mycobacterium avium subsp. paratuberculosisinfection in wild ruminants
Pruvot, Mathieu; Forde, Taya L; Steele, Jillian; Kutz, Susan J; Buck, Jeroen De; Meer, Frank van der; Orsel, Karin
included in the IDEXX ELISA kit has limited ...
... were estimated by amino acid analysis  Conjugate 
Cytotoxic properties of immunoconjugates containing melittin-like peptide 101 against prostate cancer: in vitro and in vivo studies
Cytotoxic properties of immunoconjugates containing melittin-like peptide 101 against prostate cancer: in vitro and in vivo studies
Russell, Pamela J.; Hewish, Dean; Carter, Teresa; Sterling-Levis, Katy; Ow, Kim; Hattarki, Meghan; Doughty, Larissa; Guthrie, Robin; Shapira, Deborah; Molloy, Peter L; Werkmeister, Jerome A.; Kortt, Alexander A.
batch Activation ratio Thiolation ratio ...
... response to polysaccharide antigens.  Conjugate 
Bacterial Meningitis
Bacterial Meningitis
Makwana, Nick; Riordan, F. Andrew I.
vaccines, which induce T cell memory, can ...
... of the cABD-IRDye800 peptide  conjugate 
Albumin-Binding Domain Conjugate for Near-Infrared Fluorescence Lymphatic Imaging
Albumin-Binding Domain Conjugate for Near-Infrared Fluorescence Lymphatic Imaging
Davies-Venn, Cynthia A.; Angermiller, Bonnie; Wilganowski, Nathaniel; Ghosh, Pradip; Harvey, Barrett R.; Wu, Grace; Kwon, Sunkuk; Aldrich, Melissa B.; Sevick-Muraca, Eva M.
was performed using fluorescence ...
... the minimum amount of protein needed to  conjugate 
Preparation of Colloidal Gold Particles and Conjugation to Protein A/G/L, IgG, F(ab′)2, and Streptavidin
Preparation of Colloidal Gold Particles and Conjugation to Protein A/G/L, IgG, F(ab′)2, and Streptavidin
Yokota, Sadaki
colloidal gold preparations and for ...
... The first meningococcal serogroup C (MenC)  conjugate 
Is a single dose of meningococcal serogroup C conjugate vaccine sufficient for protection? experience from the Netherlands
Is a single dose of meningococcal serogroup C conjugate vaccine sufficient for protection? experience from the Netherlands
Kaaijk, Patricia; van der Ende, Arie; Berbers, Guy; van den Dobbelsteen, Germie PJM; Rots, Nynke Y
vaccine was licensed in 1999 and introduced ...
... Prior to the introduction of pneumococcal  conjugate 
Pneumococcal Infections
Pneumococcal Infections
Klugman, Keith P.; Feldman, Charles
vaccine, the pneumococcus was also the most ...
... emtansine (T-DM1) is an antibody–drug  conjugate 
An Integrated Multiple-Analyte Pharmacokinetic Model to Characterize Trastuzumab Emtansine (T-DM1) Clearance Pathways and to Evaluate Reduced Pharmacokinetic Sampling in Patients with HER2-Positive Metastatic Breast Cancer
An Integrated Multiple-Analyte Pharmacokinetic Model to Characterize Trastuzumab Emtansine (T-DM1) Clearance Pathways and to Evaluate Reduced Pharmacokinetic Sampling in Patients with HER2-Positive Metastatic Breast Cancer
Lu, Dan; Joshi, Amita; Wang, Bei; Olsen, Steve; Yi, Joo-Hee; Krop, Ian E.; Burris, Howard A.; Girish, Sandhya
recently approved by the US Food and Drug ...
... and obinutuzumab. After purification, the  conjugate 
Near-Infrared Fluorescence Imaging of Non-Hodgkin’s Lymphoma CD20 Expression Using Cy7-Conjugated Obinutuzumab
Near-Infrared Fluorescence Imaging of Non-Hodgkin’s Lymphoma CD20 Expression Using Cy7-Conjugated Obinutuzumab
Lin, Xinfeng; Zhu, Hua; Luo, Zheng; Hong, Ye; Zhang, Hong; Liu, Xijuan; Ding, Huirong; Tian, Huifang; Yang, Zhi
was fully characterized by a series of ...
... quantifying free dye molecules in antibody  conjugate 
Assessment of Free Dye in Solutions of Dual-Labeled Antibody Conjugates for In Vivo Molecular Imaging
Assessment of Free Dye in Solutions of Dual-Labeled Antibody Conjugates for In Vivo Molecular Imaging
Aldrich, Melissa B.; Wang, XueJuan; Hart, Amy; Kwon, Sunkuk; Sampath, Lakshmi; Marshall, Milton V.; Sevick-Muraca, Eva M.
preparations is required for agent batch ...
... its target, the GRPR. A rhodamine bombesin  conjugate 
Rhodamine-marked bombesin: a novel means for prostate cancer fluorescence imaging
Rhodamine-marked bombesin: a novel means for prostate cancer fluorescence imaging
Sturzu, Alexander; Sheikh, Sumbla; Echner, Hartmut; Nägele, Thomas; Deeg, Martin; Amin, Bushra; Schwentner, Christian; Horger, Marius; Ernemann, Ulrike; Heckl, Stefan
can be used as marker to differentiate ...
... Background: The introduction of the  conjugate 
Cost Effectiveness of Pneumococcal Vaccination for Infants and Children with the Conjugate Vaccine PnC-7 in Germany
Cost Effectiveness of Pneumococcal Vaccination for Infants and Children with the Conjugate Vaccine PnC-7 in Germany
Claes, Christa; Schulenburg, Johann-Matthias Graf
vaccine PnC-7 implies that a pneumococcal ...