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... or derivatized intermediates and the  conjugate 
Glycoconjugate Vaccines
Glycoconjugate Vaccines
Ravenscroft, Neil; Costantino, Paolo; Talaga, Philippe; Rodriguez, Roberto; Egan, William
vaccine produced. ...
... Fig. 3.1 (a) Scheme of the polymer–drug  conjugate 
HPMA-Anticancer Drug Conjugates
HPMA-Anticancer Drug Conjugates
Rihova, B.; Hovorka, O.; Kovar, L.; Kovar, M.; Mrkvan, T.; Sirova, M.; Subr, V.; Ulbrich, K.
composed of water-soluble polymer chain ...
... pathway employing molecular  conjugate 
Methods for Gene Transfer Using DNA-Adenovirus Conjugates
Methods for Gene Transfer Using DNA-Adenovirus Conjugates
Curiel, David T.
vectors (1-13). ...
... (Brauch et al. 2004). The cysteine S-  conjugate 
Role of Cysteine S-Conjugate β-Lyases in the Bioactivation of Renal Toxicants
Role of Cysteine S-Conjugate β-Lyases in the Bioactivation of Renal Toxicants
Cooper, Arthur J. L.; Pinto, John T.
formed from trichloroethylene, namely ...
... of the practical steps are similar. The  conjugates 
Practical Exercises
Practical Exercises
Crowther, John R.
used are all horseradish peroxidase (HRP) ...
... B (AmB), the polyene antibiotic when  conjugated 
Amphotericin B-Gum Arabic Conjugates: Synthesis, Toxicity, Bioavailability, and Activities Against Leishmania and Fungi
Amphotericin B-Gum Arabic Conjugates: Synthesis, Toxicity, Bioavailability, and Activities Against Leishmania and Fungi
Nishi, K. K.; Antony, M.; Mohanan, P. V.; Anilkumar, T. V.; Loiseau, P. M.; Jayakrishnan, A.
to periodate oxidized gum arabic still ...
... of synthetic protocols have been set up to  conjugate 
Polysaccharide-Based Anticancer Prodrugs
Polysaccharide-Based Anticancer Prodrugs
Caliceti, Paolo; Salmaso, Stefano; Bersani, Sara
anticancer drugs to the polysaccharide ...
... Number titrated Direct Antigen; antibody  conjugated 
Titration of Reagents
Titration of Reagents
Crowther, John R.
to enzyme 2 Indirect Antigen; antibody; ...
... Polymer-drug  conjugates 
Polymer-Drug Conjugates
Polymer-Drug Conjugates
Fante, Cristina; Greco, Francesca
are nanosized drug delivery systems, which ...
... Intracellular targeted  conjugates 
Intracellular Delivery of Mitomycin C with Targeted Polysaccharide Conjugates Against Multidrug Resistance
Intracellular Delivery of Mitomycin C with Targeted Polysaccharide Conjugates Against Multidrug Resistance
Cao, Yu; Chen, Didi; Zhao, Peiguang; Liu, Lina; Huang, Xueying; Qi, Chao; Liu, Yanli; He, Hongxuan; Wang, Qian; Liu, Yang; Chen, Sha
of xyloglucan and mitomycin C (MMC) were ...
... fluorescein isothiocyanate (FITC) and the  conjugate 
Synthesis and Identification of FITC-Insulin Conjugates Produced Using Human Insulin and Insulin Analogues for Biomedical Applications
Synthesis and Identification of FITC-Insulin Conjugates Produced Using Human Insulin and Insulin Analogues for Biomedical Applications
Jacob, Dolly; Joan Taylor, M.; Tomlins, Paul; Sahota, Tarsem S.
species produced were identified using high ...
... The concept of polymer–anticancer  conjugates 
PEG–Anticancer Drugs
PEG–Anticancer Drugs
Cateni, Francesca; Zacchigna, Marina
was first proposed in 1975 by Ringsdorf, ...
... PEGylated  conjugate 
Synthesis of MCC–PEG Conjugate and Its Evaluation as a Superdisintegrant
Synthesis of MCC–PEG Conjugate and Its Evaluation as a Superdisintegrant
Bhalekar, Mangesh R.; Desale, Swapnil S.; Madgulkar, Ashwini R.
of microcrystalline cellulose (MCC) was ...
... of this study is to develop a drug-polymer  conjugate 
A Novel Rapamycin-Polymer Conjugate Based on a New Poly(Ethylene Glycol) Multiblock Copolymer
A Novel Rapamycin-Polymer Conjugate Based on a New Poly(Ethylene Glycol) Multiblock Copolymer
Tai, Wanyi; Chen, Zhijin; Barve, Ashutosh; Peng, Zhonghua; Cheng, Kun
to increase the solubility and cellular ...
... of mAbs as capture reagent; examination of  conjugates 
Monoclonal Antibodies
Monoclonal Antibodies
Crowther, John R.
5. ...
... function of a linker in an antibody–drug  conjugate 
Linker Technology and Impact of Linker Design on ADC Properties
Linker Technology and Impact of Linker Design on ADC Properties
Goldmacher, Victor S.; Singh, Rajeeva; Chittenden, Thomas; Kovtun, Yelena
is to covalently connect its effector ...
... were treated with a single dose of the  conjugate 
Preclinical Evaluation of Linear HPMA-Doxorubicin Conjugates with pH-Sensitive Drug Release: Efficacy, Safety, and Immunomodulating Activity in Murine Model
Preclinical Evaluation of Linear HPMA-Doxorubicin Conjugates with pH-Sensitive Drug Release: Efficacy, Safety, and Immunomodulating Activity in Murine Model
Sirova, Milada; Mrkvan, Tomas; Etrych, Tomas; Chytil, Petr; Rossmann, Pavel; Ibrahimova, Marketa; Kovar, Lubomir; Ulbrich, Karel; Rihova, Blanka
(15, 25, and 75 mg Dox eq./kg i.v.) in a ...
... and structurally well-defined  conjugates 
Synthesis and Εvaluation of Αnticancer Αctivity in Cells of Novel Stoichiometric Pegylated Fullerene-Doxorubicin Conjugates
Synthesis and Εvaluation of Αnticancer Αctivity in Cells of Novel Stoichiometric Pegylated Fullerene-Doxorubicin Conjugates
Magoulas, George E.; Bantzi, Marina; Messari, Danai; Voulgari, Efstathia; Gialeli, Chrisostomi; Barbouri, Despoina; Giannis, Athanassios; Karamanos, Nikos K.; Papaioannou, Dionissios; Avgoustakis, Konstantinos
of fullerene (C60) with doxorubicin (DOX) ...
... α, ω bis carboxyl PEG was covalently  conjugated 
Targeted Sialic Acid–Doxorubicin Prodrugs for Intracellular Delivery and Cancer Treatment
Targeted Sialic Acid–Doxorubicin Prodrugs for Intracellular Delivery and Cancer Treatment
Jayant, Sreeja; Khandare, Jayant J.; Wang, Yang; Singh, Ajay P.; Vorsa, Nicholi; Minko, Tamara
with multiple copies of SA and DOX through ...
... Purpose Gelatin–methotrexate  conjugates 
The Effect of Molecular Weight, Drug Load, and Charge of Gelatin–MTX Conjugates on Growth Inhibition of HL-60 Leukemia Cells
The Effect of Molecular Weight, Drug Load, and Charge of Gelatin–MTX Conjugates on Growth Inhibition of HL-60 Leukemia Cells
Chen, Chao-Sheng; Ofner, Clyde M., III
(G-MTX) with known molecular weight (MW), ...
... achieved upon treatment with Dox–PHPMA–HuIg  conjugate 
Treatment with HPMA copolymer-based doxorubicin conjugate containing human immunoglobulin induces long-lasting systemic anti-tumour immunity in mice
Treatment with HPMA copolymer-based doxorubicin conjugate containing human immunoglobulin induces long-lasting systemic anti-tumour immunity in mice
Sirova, Milada; Strohalm, Jiri; Subr, Vladimir; Plocova, Daniela; Rossmann, Pavel; Mrkvan, Tomas; Ulbrich, Karel; Rihova, Blanka
. ...
... of tricationic porphyrin–imidazophenazine  conjugate 
Binding of Metallated Porphyrin-Imidazophenazine Conjugate to Tetramolecular Quadruplex Formed by Poly(G): a Spectroscopic Investigation
Binding of Metallated Porphyrin-Imidazophenazine Conjugate to Tetramolecular Quadruplex Formed by Poly(G): a Spectroscopic Investigation
Ryazanova, Olga; Zozulya, Victor; Voloshin, Igor; Dubey, Larysa; Dubey, Igor; Karachevtsev, Victor
, to tetramolecular quadruplex structure ...
... an acute CCl4 model in mice. Results Y27-  conjugate 
Increased Liver Uptake and Reduced Hepatic Stellate Cell Activation with a Cell-Specific Conjugate of the Rho-kinase Inhibitor Y27632
Increased Liver Uptake and Reduced Hepatic Stellate Cell Activation with a Cell-Specific Conjugate of the Rho-kinase Inhibitor Y27632
Beuge, Marike Marjolijn; Prakash, Jai; Lacombe, Marie; Post, Eduard; Reker-Smit, Catharina; Beljaars, Leonie; Poelstra, Klaas
remained stable in serum, while drug was ...
... of allicin. Alliinase was chemically  conjugated 
In situ allicin generation using targeted alliinase delivery for inhibition of MIA PaCa-2 cells via epigenetic changes, oxidative stress and cyclin-dependent kinase inhibitor (CDKI) expression
In situ allicin generation using targeted alliinase delivery for inhibition of MIA PaCa-2 cells via epigenetic changes, oxidative stress and cyclin-dependent kinase inhibitor (CDKI) expression
Chhabria, Sagar V.; Akbarsha, Mohammad A.; Li, Albert P.; Kharkar, Prashant S.; Desai, Krutika B.
to a monoclonal antibody (mAb) which was ...
... newly synthesized dextrin–zidovudine (AZT)  conjugate 
A Novel Anti-HIV Dextrin–Zidovudine Conjugate Improving the Pharmacokinetics of Zidovudine in Rats
A Novel Anti-HIV Dextrin–Zidovudine Conjugate Improving the Pharmacokinetics of Zidovudine in Rats
Wannachaiyasit, Sumalee; Chanvorachote, Pithi; Nimmannit, Ubonthip
designed as a sustained release prodrug of ...