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... polymers synthesized in this program, were  conjugated 
Macromolecular Conjugates of Methotrexate, Ferrocene and Platinum in Cancer Chemotherapy
Macromolecular Conjugates of Methotrexate, Ferrocene and Platinum in Cancer Chemotherapy
Mufula, Alain I.; Neuse, Eberhard W.
with methotrexate (MTX) and with organoiron ...
... The concept of polymer–anticancer  conjugates 
PEG–Anticancer Drugs
PEG–Anticancer Drugs
Cateni, Francesca; Zacchigna, Marina
was first proposed in 1975 by Ringsdorf, ...
... of mAbs as capture reagent; examination of  conjugates 
Monoclonal Antibodies
Monoclonal Antibodies
Crowther, John R.
5. ...
... of this study is to develop a drug-polymer  conjugate 
A Novel Rapamycin-Polymer Conjugate Based on a New Poly(Ethylene Glycol) Multiblock Copolymer
A Novel Rapamycin-Polymer Conjugate Based on a New Poly(Ethylene Glycol) Multiblock Copolymer
Tai, Wanyi; Chen, Zhijin; Barve, Ashutosh; Peng, Zhonghua; Cheng, Kun
to increase the solubility and cellular ...
... of mAbs as capture reagent; examination of  conjugates 
Monoclonal Antibodies
Monoclonal Antibodies
Crowther, John R.
5. ...
... function of a linker in an antibody–drug  conjugate 
Linker Technology and Impact of Linker Design on ADC Properties
Linker Technology and Impact of Linker Design on ADC Properties
Goldmacher, Victor S.; Singh, Rajeeva; Chittenden, Thomas; Kovtun, Yelena
is to covalently connect its effector ...
... and specificity of the nanomaterial  conjugates 
Exploring cancer metastasis prevention strategy: interrupting adhesion of cancer cells to vascular endothelia of potential metastatic tissues by antibody-coated nanomaterial
Exploring cancer metastasis prevention strategy: interrupting adhesion of cancer cells to vascular endothelia of potential metastatic tissues by antibody-coated nanomaterial
Xie, Jingjing; Dong, Haiyan; Chen, Hongning; Zhao, Rongli; Sinko, Patrick J; Shen, Weiyu; Wang, Jichuang; Lu, Yusheng; Yang, Xiang; Xie, Fangwei; Jia, Lee
for capturing and down-regulating ...
... were treated with a single dose of the  conjugate 
Preclinical Evaluation of Linear HPMA-Doxorubicin Conjugates with pH-Sensitive Drug Release: Efficacy, Safety, and Immunomodulating Activity in Murine Model
Preclinical Evaluation of Linear HPMA-Doxorubicin Conjugates with pH-Sensitive Drug Release: Efficacy, Safety, and Immunomodulating Activity in Murine Model
Sirova, Milada; Mrkvan, Tomas; Etrych, Tomas; Chytil, Petr; Rossmann, Pavel; Ibrahimova, Marketa; Kovar, Lubomir; Ulbrich, Karel; Rihova, Blanka
(15, 25, and 75 mg Dox eq./kg i.v.) in a ...
... and structurally well-defined  conjugates 
Synthesis and Εvaluation of Αnticancer Αctivity in Cells of Novel Stoichiometric Pegylated Fullerene-Doxorubicin Conjugates
Synthesis and Εvaluation of Αnticancer Αctivity in Cells of Novel Stoichiometric Pegylated Fullerene-Doxorubicin Conjugates
Magoulas, George E.; Bantzi, Marina; Messari, Danai; Voulgari, Efstathia; Gialeli, Chrisostomi; Barbouri, Despoina; Giannis, Athanassios; Karamanos, Nikos K.; Papaioannou, Dionissios; Avgoustakis, Konstantinos
of fullerene (C60) with doxorubicin (DOX) ...
... α, ω bis carboxyl PEG was covalently  conjugated 
Targeted Sialic Acid–Doxorubicin Prodrugs for Intracellular Delivery and Cancer Treatment
Targeted Sialic Acid–Doxorubicin Prodrugs for Intracellular Delivery and Cancer Treatment
Jayant, Sreeja; Khandare, Jayant J.; Wang, Yang; Singh, Ajay P.; Vorsa, Nicholi; Minko, Tamara
with multiple copies of SA and DOX through ...
... Purpose Gelatin–methotrexate  conjugates 
The Effect of Molecular Weight, Drug Load, and Charge of Gelatin–MTX Conjugates on Growth Inhibition of HL-60 Leukemia Cells
The Effect of Molecular Weight, Drug Load, and Charge of Gelatin–MTX Conjugates on Growth Inhibition of HL-60 Leukemia Cells
Chen, Chao-Sheng; Ofner, Clyde M., III
(G-MTX) with known molecular weight (MW), ...
... we have: i). an element x ≠ 1 cannot be  conjugate 
Nilpotent Groups and Solvable Groups
Nilpotent Groups and Solvable Groups
Machì, Antonio
to its inverse; ii). if x n = y n then x = ...
... achieved upon treatment with Dox–PHPMA–HuIg  conjugate 
Treatment with HPMA copolymer-based doxorubicin conjugate containing human immunoglobulin induces long-lasting systemic anti-tumour immunity in mice
Treatment with HPMA copolymer-based doxorubicin conjugate containing human immunoglobulin induces long-lasting systemic anti-tumour immunity in mice
Sirova, Milada; Strohalm, Jiri; Subr, Vladimir; Plocova, Daniela; Rossmann, Pavel; Mrkvan, Tomas; Ulbrich, Karel; Rihova, Blanka
. ...
... of tricationic porphyrin–imidazophenazine  conjugate 
Binding of Metallated Porphyrin-Imidazophenazine Conjugate to Tetramolecular Quadruplex Formed by Poly(G): a Spectroscopic Investigation
Binding of Metallated Porphyrin-Imidazophenazine Conjugate to Tetramolecular Quadruplex Formed by Poly(G): a Spectroscopic Investigation
Ryazanova, Olga; Zozulya, Victor; Voloshin, Igor; Dubey, Larysa; Dubey, Igor; Karachevtsev, Victor
, to tetramolecular quadruplex structure ...
... an acute CCl4 model in mice. Results Y27-  conjugate 
Increased Liver Uptake and Reduced Hepatic Stellate Cell Activation with a Cell-Specific Conjugate of the Rho-kinase Inhibitor Y27632
Increased Liver Uptake and Reduced Hepatic Stellate Cell Activation with a Cell-Specific Conjugate of the Rho-kinase Inhibitor Y27632
Beuge, Marike Marjolijn; Prakash, Jai; Lacombe, Marie; Post, Eduard; Reker-Smit, Catharina; Beljaars, Leonie; Poelstra, Klaas
remained stable in serum, while drug was ...
... of catalytic asymmetric cycloaddition and  conjugate 
Secondary and Primary Amine Catalysts for Iminium Catalysis
Secondary and Primary Amine Catalysts for Iminium Catalysis
Brazier, John B.; Tomkinson, Nicholas C. O.
addition reactions. ...
... Three  conjugate 
Some nonlinear conjugate gradient methods based on spectral scaling secant equations
Some nonlinear conjugate gradient methods based on spectral scaling secant equations
Liu, Hao; Yao, Yi; Qian, Xiaoyan; Wang, Haijun
gradient methods based on the spectral ...
... the lower and upper bounds on the first  conjugate 
Maxwell Strata and Conjugate Points in the Sub-Riemannian Problem on the Lie Group SH(2)
Maxwell Strata and Conjugate Points in the Sub-Riemannian Problem on the Lie Group SH(2)
Butt, Yasir Awais; Sachkov, Yuri L.; Bhatti, Aamer Iqbal
times. ...
... Site-selectivity in  conjugate 
Site-Selective Conjugate Addition Through Catalytic Generation of Ion-Pairing Intermediates
Site-Selective Conjugate Addition Through Catalytic Generation of Ion-Pairing Intermediates
Uraguchi, Daisuke; Ooi, Takashi
addition reactions is tightly associated ...
... to develop new methodologies to expand the  conjugate 
Conjugate Addition of Organoaluminum Species to Michael Acceptors and Related Processes
Conjugate Addition of Organoaluminum Species to Michael Acceptors and Related Processes
Pàmies, Oscar; Diéguez, Montserrat
addition and related processes to the use ...
... position (near or far), the dark  conjugate 
The horizontal dark oculomotor rest position
The horizontal dark oculomotor rest position
Kim, Eun H.; Alvarez, Tara L.
position (left to right), and the near ...
... we need to know the distribution of the  conjugate 
The adjacency graphs of some feedback shift registers
The adjacency graphs of some feedback shift registers
Li, Ming; Jiang, Yupeng; Lin, Dongdai
pairs in the cycles of the FSR, which is ...
... We compute the  conjugate 
Central conjugate locus of 2-step nilpotent Lie groups
Central conjugate locus of 2-step nilpotent Lie groups
Eberlein, Patrick
locus with multiplicities of a geodesic ...
... of allicin. Alliinase was chemically  conjugated 
In situ allicin generation using targeted alliinase delivery for inhibition of MIA PaCa-2 cells via epigenetic changes, oxidative stress and cyclin-dependent kinase inhibitor (CDKI) expression
In situ allicin generation using targeted alliinase delivery for inhibition of MIA PaCa-2 cells via epigenetic changes, oxidative stress and cyclin-dependent kinase inhibitor (CDKI) expression
Chhabria, Sagar V.; Akbarsha, Mohammad A.; Li, Albert P.; Kharkar, Prashant S.; Desai, Krutika B.
to a monoclonal antibody (mAb) which was ...
... newly synthesized dextrin–zidovudine (AZT)  conjugate 
A Novel Anti-HIV Dextrin–Zidovudine Conjugate Improving the Pharmacokinetics of Zidovudine in Rats
A Novel Anti-HIV Dextrin–Zidovudine Conjugate Improving the Pharmacokinetics of Zidovudine in Rats
Wannachaiyasit, Sumalee; Chanvorachote, Pithi; Nimmannit, Ubonthip
designed as a sustained release prodrug of ...