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... complex matrices. As the mixture  complexity 
Use of an informed search space maximizes confidence of site-specific assignment of glycoprotein glycosylation
Use of an informed search space maximizes confidence of site-specific assignment of glycoprotein glycosylation
Khatri, Kshitij; Klein, Joshua A.; Zaia, Joseph
increases, the naïve search space balloons ...
... to come to grips with the volume and  complexity 
Quantitative mass spectrometry in proteomics: critical review update from 2007 to the present
Quantitative mass spectrometry in proteomics: critical review update from 2007 to the present
Bantscheff, Marcus; Lemeer, Simone; Savitski, Mikhail M.; Kuster, Bernhard
of the data generated. ...
... of interest by reducing the sequence  complexity 
Targeted next-generation sequencing by specific capture of multiple genomic loci using low-volume microfluidic DNA arrays
Targeted next-generation sequencing by specific capture of multiple genomic loci using low-volume microfluidic DNA arrays
Bau, Stephan; Schracke, Nadine; Kränzle, Marcel; Wu, Haiguo; Stähler, Peer F.; Hoheisel, Jörg D.; Beier, Markus; Summerer, Daniel
of the sample. ...
... model, and the criteria used to define the  complexity 
Selection of useful predictors in multivariate calibration
Selection of useful predictors in multivariate calibration
Forina, M.; Lanteri, S.; Oliveros, M. C. Cerrato; Millan, C. Pizarro
of PLS models. ...
... sample before PCR, increasing microfluidic  complexity 
Emerging optofluidic technologies for point-of-care genetic analysis systems: a review
Emerging optofluidic technologies for point-of-care genetic analysis systems: a review
Brennan, Desmond; Justice, John; Corbett, Brian; McCarthy, Tommie; Galvin, Paul
. ...
... The preferred Tucker model of definite  complexity 
Chemometric analysis of soil pollution data using the Tucker N-way method
Chemometric analysis of soil pollution data using the Tucker N-way method
Stanimirova, I.; Zehl, K.; Massart, D. L.; Heyden, Y.; Einax, J. W.
showed that there was no significant ...
... to address two fundamental issues:  complexity 
The need for external validation in machine olfaction: emphasis on health-related applications
The need for external validation in machine olfaction: emphasis on health-related applications
Marco, Santiago
control (also known as model selection) ...
... computations, these systems have limited  complexity 
Enzyme-based logic gates and circuits—analytical applications and interfacing with electronics
Enzyme-based logic gates and circuits—analytical applications and interfacing with electronics
Katz, Evgeny; Poghossian, Arshak; Schöning, Michael J.
and further increase of their ...
... of variables, level of noise, and expected  complexity 
Identification of heparin samples that contain impurities or contaminants by chemometric pattern recognition analysis of proton NMR spectral data
Identification of heparin samples that contain impurities or contaminants by chemometric pattern recognition analysis of proton NMR spectral data
Zang, Qingda; Keire, David A.; Buhse, Lucinda F.; Wood, Richard D.; Mital, Dinesh P.; Haque, Syed; Srinivasan, Shankar; Moore, Christine M. V.; Nasr, Moheb; Al-Hakim, Ali; Trehy, Michael L.; Welsh, William J.
required for class separation. ...
... nanometrological applications. Given the  complexity 
Biomacromolecules as tools and objects in nanometrology—current challenges and perspectives
Biomacromolecules as tools and objects in nanometrology—current challenges and perspectives
Hashemi, Payam; Luckau, Luise; Mischnick, Petra; Schmidt, Sarah; Stosch, Rainer; Wünsch, Bettina
of biomacromolecules, quantitative ...
... leading to a method whose computational  complexity 
Improved quantification of important beer quality parameters based on nonlinear calibration methods applied to FT-MIR spectra
Improved quantification of important beer quality parameters based on nonlinear calibration methods applied to FT-MIR spectra
Cernuda, Carlos; Lughofer, Edwin; Klein, Helmut; Forster, Clemens; Pawliczek, Marcin; Brandstetter, Markus
and virtual memory requirement is linear ...
... chemical information, has achieved higher  complexity 
Digital biosensors with built-in logic for biomedical applications—biosensors based on a biocomputing concept
Digital biosensors with built-in logic for biomedical applications—biosensors based on a biocomputing concept
Wang, Joseph; Katz, Evgeny
of information processing compared with ...
... efficiency was checked by visualizing the  complexity 
Development of an analytical procedure for quantifying the underivatized neurotoxin β-N-methylamino-l-alanine in brain tissues
Development of an analytical procedure for quantifying the underivatized neurotoxin β-N-methylamino-l-alanine in brain tissues
Combes, Audrey; Abdellaoui, Saïda; Vial, Jérome; Lagrange, Emmeline; Pichon, Valérie; BMAALS group
of the resulting chromatograms in LC/MS ...
... Chemical peptide labeling (MS) Medium  complexity 
Quantitative mass spectrometry in proteomics: a critical review
Quantitative mass spectrometry in proteomics: a critical review
Bantscheff, Marcus; Schirle, Markus; Sweetman, Gavain; Rick, Jens; Kuster, Bernhard
biochemical workflows ++ ++ 2 logs ...
... are the methods of choice to assess the  complexity 
Intraspecific variations in Conus purpurascens injected venom using LC/MALDI-TOF-MS and LC-ESI-TripleTOF-MS
Intraspecific variations in Conus purpurascens injected venom using LC/MALDI-TOF-MS and LC-ESI-TripleTOF-MS
Rodriguez, Alena M.; Dutertre, Sebastien; Lewis, Richard J.; Marí, Frank
and variability of animal venom. ...
... and at the same time of unraveling the  complexity 
High-throughput, multiparameter analysis of single cells
High-throughput, multiparameter analysis of single cells
Haselgrübler, Thomas; Haider, Michaela; Ji, Bozhi; Juhasz, Kata; Sonnleitner, Alois; Balogi, Zsolt; Hesse, Jan
and interdependence of cellular processes ...
... the electrode activity. The increasing  complexity 
Electrode interfaces switchable by physical and chemical signals for biosensing, biofuel, and biocomputing applications
Electrode interfaces switchable by physical and chemical signals for biosensing, biofuel, and biocomputing applications
Katz, Evgeny; Minko, Segiy; Halámek, Jan; MacVittie, Kevin; Yancey, Kenneth
in the signal processing was achieved by ...
... plates. These strategies often introduce  complexity 
Mitigation of microtiter plate positioning effects using a block randomization scheme
Mitigation of microtiter plate positioning effects using a block randomization scheme
Roselle, Christopher; Verch, Thorsten; Shank-Retzlaff, Mary
while only partially mitigating positional ...
... and tissue samples. However, sample  complexity 
Offline pentafluorophenyl (PFP)-RP prefractionation as an alternative to high-pH RP for comprehensive LC-MS/MS proteomics and phosphoproteomics
Offline pentafluorophenyl (PFP)-RP prefractionation as an alternative to high-pH RP for comprehensive LC-MS/MS proteomics and phosphoproteomics
Grassetti, Andrew V.; Hards, Rufus; Gerber, Scott A.
necessitates offline prefractionation via ...
... is a challenging task, due to the chemical  complexity 
Chromatographic profiles of Phyllanthus aqueous extracts samples: a proposition of classification using chemometric models
Chromatographic profiles of Phyllanthus aqueous extracts samples: a proposition of classification using chemometric models
Martins, Lucia Regina Rocha; Pereira-Filho, Edenir Rodrigues; Cass, Quezia Bezerra
of the vegetal and to the fact that ...
... implement classifiers of an adjustable  complexity 
Application of support vector machines to 1H NMR data of fish oils: methodology for the confirmation of wild and farmed salmon and their origins
Application of support vector machines to 1H NMR data of fish oils: methodology for the confirmation of wild and farmed salmon and their origins
Masoum, Saeed; Malabat, Christophe; Jalali-Heravi, Mehdi; Guillou, Claude; Rezzi, Serge; Rutledge, Douglas Neil
, controlling the latter for optimal ...
... order to construct the PLS-DA model, its  complexity 
Detection of discoloration in diesel fuel based on gas chromatographic fingerprints
Detection of discoloration in diesel fuel based on gas chromatographic fingerprints
Krakowska, Barbara; Stanimirova, Ivana; Orzel, Joanna; Daszykowski, Michal; Grabowski, Ireneusz; Zaleszczyk, Grzegorz; Sznajder, Miroslaw
is optimized so that the covariance ...
... [71, 79–81]. Basis for the spectral  complexity 
Single-molecule spectroscopy of fluorescent proteins
Single-molecule spectroscopy of fluorescent proteins
Blum, Christian; Subramaniam, Vinod
of VFPs Clearly, chromophore formation in ...
... winemakers and scientists researching the  complexity 
Beyond the characterization of wine aroma compounds: looking for analytical approaches in trying to understand aroma perception during wine consumption
Beyond the characterization of wine aroma compounds: looking for analytical approaches in trying to understand aroma perception during wine consumption
Muñoz-González, Carolina; Rodríguez-Bencomo, Juan J.; Moreno-Arribas, M. Victoria; Pozo-Bayón, M. Ángeles
of wine aroma. ...
... treated either individually (low  complexity 
An insight into iTRAQ: where do we stand now?
An insight into iTRAQ: where do we stand now?
Evans, Caroline; Noirel, Josselin; Ow, Saw Yen; Salim, Malinda; Pereira-Medrano, Ana G.; Couto, Narciso; Pandhal, Jagroop; Smith, Duncan; Pham, Trong Khoa; Karunakaran, Esther; Zou, Xin; Biggs, Catherine A.; Wright, Phillip C.
sample) or spiked into a high- ...

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