Springer Exemplar

... Background MCT-1 oncoprotein accelerates	p53 Molecular Cancer The antagonism between MCT-1 and p53 affects the tumorigenic outcomes Kasiappan, Ravi; Shih, Hung-Ju; Wu, Meng-Hsun; Choy, ChikOn; Lin, Tai-Du; Chen, Linyi; Hsu, Hsin-Ling	protein degradation via a proteosome pathway. ...
... The	p53 Signaling Pathways in Liver Diseases p53 Tsai, Wen-Wei; Barton, Michelle Craig	tumor suppressor is well known as the major ...
... Mutations in the TP53 gene or the	p53 CNS Cancer p53 Pathway Alterations in Brain Tumors Yin, Shaoman; Van Meir, Erwin G.	pathway are required for the formation of many ...
... Understanding the mechanism underlying	p53 Journal of Neuro-Oncology Simultaneous phosphorylation of p53 at serine 15 and 20 induces apoptosis in human glioma cells by increasing expression of pro-apoptotic genes Amano, Toshiyuki; Nakamizo, Akira; Mishra, Sandip K.; Gumin, Joy; Shinojima, Naoki; Sawaya, Raymond; Lang, Frederick F.	’s ability to induce cell cycle arrest versus ...
...	p53 Signal Transduction: Pathways, Mechanisms and Diseases Activation of the p53 Tumor Suppressor and its Multiple Roles in Cell Cycle and Apoptosis Giono, Luciana E.; Manfredi, James J.	is a widely conserved tumor suppressor protein ...
...	p53 Apoptosis Targeting p53 for enhanced radio- and chemo-sensitivity Lu, Chao; El-Deiry, Wafik S.	acts as a central mediator of the cellular ...
... Background The tumor suppressor gene	p53 Molecular Cancer Expression of full-length p53 and its isoform Δp53 in breast carcinomas in relation to mutation status and clinical parameters Baumbusch, Lars; Myhre, Simen; Langerød, Anita; Bergamaschi, Anna; Geisler, Stephanie; Lønning, Per; Deppert, Wolfgang; Dornreiter, Irene; Børresen-Dale, Anne-Lise	(TP53) controls numerous signaling pathways and ...
...	p53 25 Years of p53 Research Regulation of p53 DNA Binding McKinney, Kristine; Prives, Carol	is one of the most frequently mutated genes in ...
... The	p53 Lung Cancer Clinical Implications of p53 Mutations in Lung Cancer Campling, Barbara G.; El-Deiry, Wafik S.	tumor-suppressor gene plays a crucial role in the ...
... No summary available 1 The	p53 Sensitization of Cancer Cells for Chemo/Immuno/Radio-therapy p53 Inhibitors as Cancer Sensitizing Agents Maina, Flavio; Dono, Rosanna	Player: A Stage Director for the Fate of Stressed ...
... Introduction Normal function of the	p53 Breast Cancer Research p53 mutant breast cancer patients expressing p53γ have as good a prognosis as wild-type p53 breast cancer patients Bourdon, Jean-Christophe; Khoury, Marie P; Diot, Alexandra; Baker, Lee; Fernandes, Kenneth; Aoubala, Mustapha; Quinlan, Philip; Purdie, Colin A; Jordan, Lee B; Prats, Anne-Catherine; Lane, David P; Thompson, Alastair M	network is lost in most cancers, often through ...
... Background The	p53 Biology Direct Impact of Alu repeats on the evolution of human p53 binding sites Cui, Feng; Sirotin, Michael V; Zhurkin, Victor B	tumor suppressor protein is involved in a ...
... In this work we present evidence that the	p53 BMC Immunology Modulation of p53 activity by IκBα: Evidence suggesting a common phylogeny between NF-κB and p53 transcription factors Dreyfus, David; Nagasawa, Masayuki; Gelfand, Erwin; Ghoda, Lucy	tumor suppressor protein and NF-κB transcription ...
... Happy 25th Anniversary	p53 25 Years of p53 Research Gatekeepers of the Guardian: p53 Regulation by Post-Translational Modification, MDM2 and MDMX Wahl, Geoffrey M.; Stommel, Jayne M.; Krummel, Kurt; Wade, Mark	! Since this is such a special occasion, I (GW) ...
... Single mutations in the DNA binding domain of	p53 The p53 Tumor Suppressor Pathway and Cancer The Oncogenic Activity of p53 Mutants Sigal, Alex; Rotter, Varda	cause a radical shift in function from tumor ...
... The	p53 The p53 Tumor Suppressor Pathway and Cancer p53 in Human Cancer — Somatic and Inherited Mutations and Mutation-independent Mechanisms Moll, Ute M.; Concin, Nicole	tumor suppressor protein plays a central role in ...
... The best-characterized function of	p53 The p53 Tumor Suppressor Pathway and Cancer Transcriptional Activation by p53: Mechanisms and Targeted Genes MacLachlan, Timothy; El-Deiry, Wafik	, the most renowned tumor suppressor, is that of ...
... The	p53 Cancer and Metastasis Reviews The p53 protein family and radiation sensitivity: Yes or no? Cuddihy, Andrew R.; Bristow, Robert G.	tumor suppressor protein is a key mediator of an ...
...	p53 Journal of Molecular Medicine Exonucleolytic degradation of RNA by p53 protein in cytoplasm Bakhanashvili, Mary; Gedelovich, Rachel; Grinberg, Shai; Rahav, Galia	in cytoplasm displays an intrinsic 3′→5′ ...
... The human mutant	p53 Transgenic Research Lung specific expression of a human mutant p53 affects cell proliferation in transgenic mice Duan, Wenrui; Gao, Li; Jin, David; Otterson, Gregory A.; Villalona-Calero, Miguel A.	(273H) has been shown in vitro to have both ...
... been shown to inactivate tumor suppressor protein	p53 Mortalin Biology: Life, Stress and Death Mortalin-p53 Interaction as a Target for Liver Cancer Therapy Lu, Wen-Jing; Lee, Nikki P.; Wadhwa, Renu; Luk, John M.	. ...
...	p53 Transgenic Research Mice defective in p53 nuclear localization signal 1 exhibit exencephaly Regeling, Anouk; Armata, Heather L.; Gallant, Judy; Jones, Stephen N.; Sluss, Hayla K.	is a major suppressor of human malignancy. ...
... Background The tumor suppressor protein	p53 BMC Genomics p53 induces distinct epigenetic states at its direct target promoters Vrba, Lukas; Junk, Damian; Novak, Petr; Futscher, Bernard	is a transcription factor that is mutated in many ...
... the best-characterized DNA repair function of	p53 Nucleic Acids Research Dissecting the role of p53 phosphorylation in homologous recombination provides new clues for gain-of-function mutants Restle, Anja; Färber, Martin; Baumann, Cindy; Böhringer, Michael; Scheidtmann, Karl Heinz; Müller-Tidow, Carsten; Wiesmüller, Lisa	. ...
... Background	p53 Molecular Cancer P53 and p73 differ in their ability to inhibit glucocorticoid receptor (GR) transcriptional activity Zhang, Lili; Nie, Linghu; Maki, Carl	is a tumor suppressor and potent inhibitor of ...

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